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A Single Nucleotide Polymorphism in LOC534614 as an Unknown Gene Associated with Body Weight and Cold Carcass Weight in Hanwoo (Korean Cattle)

  • Lee, Y.S.;Oh, D.Y.;Kim, J.J.;Lee, J.H.;Park, H.S.;Yeo, J.S.
    • Asian-Australasian Journal of Animal Sciences
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    • v.23 no.12
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    • pp.1543-1551
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    • 2010
  • A major aim of cattle genome research is to identify candidate genes associated with meat quantity and quality through QTL analysis for application in the livestock industry. Therefore, this study focused on discovery of useful SNPs within the LOC534614 gene, containing 12273_165 SNP which is located on the same site as the QTL on chromosome 6, and evaluation of the association between SNP and body weight and cold carcass weight in Hanwoo (Korean cattle) As a result of a BLAST search of the NCBI web site, we discovered that the mRNA sequence of the LOC534614 gene was similar to that of the coiled-coil domain containing 158 (CCDC158) for dog and human. According to the direct DNA sequence from the CCDC158 gene, we identified 19 polymorphic SNPs within exons and their flanking regions. Among them, 17 polymorphic SNPs were selected for genotyping in Hanwoo (n = 476) and seventeen marker haplotypes containing 12273_165 SNP (frequency >0.1) were identified. As a result of the association between 17 polymorphic SNPs and Hanwoo (n = 476), g.8778G>A SNP in exon 6 was found to be a non-synonymous SNP, and was significantly associated with body weight and cold carcass weight (p<0.05). We discovered 19 polymorphic SNPs in the CCDC158 gene on the QTL region of BTA 6 in Hanwoo and identified that the g.8778G>A SNP was significantly associated with body weight and cold carcass weight (p<0.05), which causes an amino acid variation from valine to methionine. Furthermore, statistical analysis demonstrated that the CCDC158 gene is strongly associated with body weight and cold carcass weight in Hanwoo. In this regard, the g.8778G>A SNP in the CCDC158 gene can be useful as a positional candidate for body weight and cold carcass weight for marker-assisted selection in Hanwoo.

An improved particle swarm optimizer for steel grillage systems

  • Erdal, Ferhat;Dogan, Erkan;Saka, Mehmet Polat
    • Structural Engineering and Mechanics
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    • v.47 no.4
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    • pp.513-530
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    • 2013
  • In this paper, an improved version of particle swarm optimization based optimum design algorithm (IPSO) is presented for the steel grillage systems. The optimum design problem is formulated considering the provisions of American Institute of Steel Construction concerning Load and Resistance Factor Design. The optimum design algorithm selects the appropriate W-sections for the beams of the grillage system such that the design constraints are satisfied and the grillage weight is the minimum. When an improved version of the technique is extended to be implemented, the related results and convergence performance prove to be better than the simple particle swarm optimization algorithm and some other metaheuristic optimization techniques. The efficiency of different inertia weight parameters of the proposed algorithm is also numerically investigated considering a number of numerical grillage system examples.

Robust Motion Compensated Frame Interpolation Using Weight-Overlapped Block Motion Compensation with Variable Block Sizes to Reduce LCD Motion Blurs

  • Lee, Jichan;Choi, Jin Hyuk;Lee, Daeho
    • Journal of the Optical Society of Korea
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    • v.19 no.5
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    • pp.537-543
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    • 2015
  • Liquid crystal displays (LCDs) have slow responses, so motion blurs are often perceived in fast moving scenes. To reduce this motion blur, we propose a novel method of robust motion compensated frame interpolation (MCFI) based on bidirectional motion estimation (BME) and weight-overlapped block motion compensation (WOBMC) with variable block sizes. In most MCFI methods, a static block size is used, so some block artefacts and motion blurs are observed. However, the proposed method adjusts motion block sizes and search ranges by comparing matching scores, so the precise motion vectors can be estimated in accordance with motions. In the MCFI, overlapping ranges for WOBMC are also determined by adjusted block sizes, so the accurate MCFI can be performed. In the experimental results, the proposed method strongly reduced motion blurs arisen from large motions, and yielded interpolated images with high visual performance and peak signal-to-noise ratio (PSNR).

Minimum Weight Design of Stiffened Laminated Composite Cylindrical Panel with R Type Stiffener (R형 보강재로 보강된 복합적층 원통형패널의 최소중량화설계)

  • 원종진;이종선;홍석주
    • Proceedings of the KAIS Fall Conference
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    • 2001.05a
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    • pp.103-107
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    • 2001
  • This study is simulation about buckling behavior under axial compression which is cylindrical panel laminated USN125 and USN150 made by various winding angle. And also this study compare with linear and nonlinear FDEM theory, and FEM theory. To solve the objective function and the design variables, this study use the linear and nonlinear buckling theories or FDEM and nonlinear search optimum design method of ADS for minimum weight design on which stiffened laminated composite cylindrical panel with stiffener that R-type section.

An XML Tag Indexing Method Using on Lexical Similarity (XML 태그를 분류에 따른 가중치 결정)

  • Jeong, Hye-Jin;Kim, Yong-Sung
    • The KIPS Transactions:PartB
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    • v.16B no.1
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    • pp.71-78
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    • 2009
  • For more effective index extraction and index weight determination, studies of extracting indices are carried out by using document content as well as structure. However, most of studies are concentrating in calculating the importance of context rather than that of XML tag. These conventional studies determine its importance from the aspect of common sense rather than verifying that through an objective experiment. This paper, for the automatic indexing by using the tag information of XML document that has taken its place as the standard for web document management, classifies major tags of constructing a paper according to its importance and calculates the term weight extracted from the tag of low weight. By using the weight obtained, this paper proposes a method of calculating the final weight while updating the term weight extracted from the tag of high weight. In order to determine more objective weight, this paper tests the tag that user considers as important and reflects it in calculating the weight by classifying its importance according to the result. Then by comparing with the search performance while using the index weight calculated by applying a method of determining existing tag importance, it verifies effectiveness of the index weight calculated by applying the method proposed in this paper.

A Study on the Comparative Method of Prescription Using Herb Weight Ratio (방제의 본초 중량비를 활용한 방제 비교 방안에 관한 연구)

  • Park, Daesik;Lee, Bookyun;Lee, Byung Wook
    • Herbal Formula Science
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    • v.21 no.2
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    • pp.121-132
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    • 2013
  • Objectives : The objectives of this study is to establish data-base to find out similar herbal formulas with a particular herbal formula by comparing composition ratio of configuring herbs. And this thesis is to analyze differences of prescriptions and find out similar prescriptions by utilizing galenical mass ratio, which is directly related to effectiveness of galenical. Methods : This study was proceeded by using Access 2007 with Window 7(MS) and 2,787 prescriptions of which herbal configuration could be indicated by weight unit were analysed from Donguibogam. We standardize all units of the prescription and input the mass ratio data when entered galenical data. Results : We could confirm a degree of similarity between compared prescriptions and a particular prescription according to the sum of differences of herb weight ratio and similarity ratio. Conclusions : A most similar herbal formula could be searched through comparing multi prescriptions by multi prescriptions of herbal configuration from established herbal formula data-base where herb weight ratio of prescriptions is to be input.

Method of Related Document Recommendation with Similarity and Weight of Keyword (키워드의 유사도와 가중치를 적용한 연관 문서 추천 방법)

  • Lim, Myung Jin;Kim, Jae Hyun;Shin, Ju Hyun
    • Journal of Korea Multimedia Society
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    • v.22 no.11
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    • pp.1313-1323
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    • 2019
  • With the development of the Internet and the increase of smart phones, various services considering user convenience are increasing, so that users can check news in real time anytime and anywhere. However, online news is categorized by media and category, and it provides only a few related search terms, making it difficult to find related news related to keywords. In order to solve this problem, we propose a method to recommend related documents more accurately by applying Doc2Vec similarity to the specific keywords of news articles and weighting the title and contents of news articles. We collect news articles from Naver politics category by web crawling in Java environment, preprocess them, extract topics using LDA modeling, and find similarities using Doc2Vec. To supplement Doc2Vec, we apply TF-IDF to obtain TC(Title Contents) weights for the title and contents of news articles. Then we combine Doc2Vec similarity and TC weight to generate TC weight-similarity and evaluate the similarity between words using PMI technique to confirm the keyword association.

A Fuzzy Evaluation Method of Traveler's Path Choice in Transportation Network (퍼지평가방법을 이용한 교통노선 결정)

  • 이상훈;김덕영;김성환
    • Journal of Korean Society of Transportation
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    • v.20 no.1
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    • pp.65-76
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    • 2002
  • This study is realized using fuzzy evaluation and AHP(the analytic hierarchy process) for the optimum search of traffic route and estimated by the quantitative analysis in the vague subjective judgement. It is different from classical route search and noticed thinking method of human. Appraisal element, weight, appraisal value of route is extracted from basic of the opinion gathering fur the driving expert and example of route model was used for the finding of practice utility. Model assessment was performed attribute membership function making of estimate element, estimate value setting, weight define by the AHP, non additive presentation of weight according to $\lambda$-fuzzy measure, Choquet fuzzy integral.

The Extended k-opt Algorithm for Traveling Salesman Problem (외판원 문제의 확장된 k-opt 알고리즘)

  • Lee, Sang-Un
    • Journal of the Korea Society of Computer and Information
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    • v.17 no.10
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    • pp.155-165
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    • 2012
  • This paper suggests traveling salesman problem algorithm that have been unsolved problem with NP-Hard. The proposed algorithm is a heuristic with edge-swap method. The classical method finds the initial solution starts with first node and visits to mostly adjacent nodes then decides the traveling path. This paper selects minimum weight edge for each nodes, then perform Min-Min method that start from minimum weight edge among the selected edges and Min-Max method that starts from maximum weight edges among it. Then we decide tie initial solution to minimum path length between Min-Min and Min-Max method. To get the final optimal solution, we apply previous two-opt to initial solution. Also, we suggest extended 3-opt and 4-opt additionally. For the 7 actual experimental data, this algorithm can be get the optimal solutions of state-of-the-art with fast and correct.

Literature Review of Herbal Medicines on Treatment of Obesity Since 2000;Mainly about Ephedra Herba (2000년 이후 비만치료에 사용되는 처방(處方) 및 본초(本草)에 대한 문헌연구;마황(麻黃)을 중심으로)

  • Hwang, Mi-Ja;Shin, Hyun-Da;Song, Mi-Yeon
    • Journal of Korean Medicine for Obesity Research
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    • v.7 no.1
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    • pp.39-54
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    • 2007
  • Objectives : This study has been done to know which herbs and herbal formulae are frequently used for the treatment of obesity in Korea and overseas since 2000. Methods : We conducted a computerized literature search in KISS (Korean studies Information Service System), Pubmed, Journal of Oriental Association for Study of Obesity ,and Journal of Oriental Rehabilitation Medicine(2000 -Apr. 2006) using search key words obesity, obese, weight loss, weight control combined with herb, herbal formula. Result and conclusion : Seventy-two studies have been identified(50 Korean papers and 22 pubmed papers) and 81 herbs have been found. In USA it was mainly used as single herb for food, but in Korea it was mainly used as herbal formula. For single herb, ephedra(麻黃) was the most studied single herb both in Korea and the USA. For herbal formulae, Sasang Constitutional Medicine(SCM, 19times) was the most frequently used herbal formula, in which the herbs for Tae-eum type person like Taeyeumjowui-tang(太陰調胃湯, 7times) and Choweseungcheng-tang(調胃升淸湯, 5times) were mainly prescribed. The next was Chegameuiin-tang(體減薏苡仁湯, 11times) and Bangpungtongsungsan( 防風通聖散, 3times). Calculating each herb consisted in each herbal formula, Coicis Semen(薏苡仁), Angelicae gigantis Radix(當歸), and Glycyrrhizae Radix(甘草), Raspberry Ketone, Cnidii Rhizoma(川芎), and Ephedra Herba(麻黃) turned out to be the most frequently used herb.

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