• 생약학회지
• /
• 제23권4호
• /
• pp.264-267
• /
• 1992

The cytotoxic activity of medicinal plants was screened using A549 human lung cancer cell line. Plant materials were extracted with 80% methanol and fractionated to chloroform and water layers. Each methanol, chloroform, and water extract of thirty-two medicinal plants was tested for cytotoxic activity in A549 cell culture system and the cell viability was measured by SRB assay.

• 한국경영과학회:학술대회논문집
• /
• 대한산업공학회/한국경영과학회 1994년도 춘계공동학술대회논문집; 창원대학교; 08월 09일 Apr. 1994
• /
• pp.467-477
• /
• 1994

The objective of this research is to develop a manufacturability measurement model for process and material screening. The process and material screening is the key requirement for implementing the Design for Manufacturability (Concurrent Engineering). A computerized system realizing this model then is developed to aid designers. Identification of the key factors which influence technical manufacturability, decision variables and their characteristics, conceptual framework for implementing the model are suggested. Manufacturability measure for quantifying the consistency of between the product requirements and the manufacturing capability is important contribution of this research. The focus is on net shape manufacturing process such as diecasting, forging, metal forming and injection molding.

• 산업경영시스템학회지
• /
• 제11권18호
• /
• pp.27-34
• /
• 1988

This study is concerned with the development of the economic sampling inspection plan when it is possible to carry out a nondestructive screening inspection for the rejected lots by substitutive characteristics closely related to the original quality characteristic. It is assumed that the probabilities of those errors depend linearly on the fraction defective of the process sampling inspection policy for isolated lot is studied where the probability of accepting the lot with bad quality from the results of sampling inspection is restricted to be small.

• Journal of Yeungnam Medical Science
• /
• 제8권2호
• /
• pp.150-157
• /
• 1991

보건연구개발 사업을 위한 지역사회 진단의 일환으로 도시 영세지역 주민을 대상으로 시행한 건강진단 조사의 결과를 요약하면 다음과 같다. 전체 대상주민 2,591명중 건강진단에 참여한 영세지역 주민은 437명(16.9%)였으며 남자는 9.9% 여자는 23.9%가 참여하였다. 연령별로는 60세 이상군이 42%로 가장 높은 참여율을 나타냈고 20-29세군이 5.9%로 가장 낮았다. 건강진단에서 이상소견율은 남자가 38.7%, 여자가 45.8%였으며 전체적으로 43.7%였고 연령별로는 60세 이상군이 69.8%로 가장 높고 10-19세군이 10.9%로 가장 낮았다. 국제질병분류(ICD 17 대분류)에 의한 질병분포는 소화기계 질병이 23.7%로 가장 높았고 순환기계 질병 19.7%, 신경계 및 감각기 질병 13.2% 순이었다. Screening test에서 헤마토크릿치가 낮은 경우가 14.6%, 고혈압이 10.1%, 청력손실 5.5%, 간기능이상 4.1%, 당뇨가 2.3%, 단백뇨가 1.4%, chest X-선상 이상소견이 0.9%였다.

• 핵의학기술
• /
• 제13권3호
• /
• pp.185-188
• /
• 2009

목적 : 건진센터 종양 검사가 정상범위 내에서 재검기준이 명확히 설정되어 있지 않아 검사자마다 각자의 재검기준에 따라 재검을 시행함에 따라 재검상의 편차가 크고 일괄적이지 못했다. 이를 개선하기 위해 정상치이하값에서의 재검기준을 마련하고 정상치이하인 값에서 trend 결과를 관리할 수 있는 본원 OCS QC (order communication system quality control)프로그램을 이용하여 건진 센터 종양 검사의 결과보고오류에 개선을 하고자 한다. 대상 및 방법 : 2009년 2월부터 3월까지 본원 건진 센터에서 종양 검사(AFP, CEA, CA19-9, CA125, PSA)를 실시한 환자들을 대상으로 하였다. 우선 각 검사의 정상범위에서 Inter assay CV%를 구하여 screening 기준 값을 설정하였다. OCS QC program에 진료과, 대상 검사종목, screening 기준 값을 입력하여 기준 값에 벗어난 결과는 색깔에 반전을 주었다. 1차로 5가지종양 검사를 전 결과대비 ${\pm}$ 30% 기준을 벗어난 screening 건수를 구하였고 2차로 각각의 종양 검사에 대해 전 결과 대비 AFP는 ${\pm}$ 60%, CEA와 CA19-9는 ${\pm}$50%, CA125와 PSA는 ${\pm}$40%로 기준 값을 상향조정하여 screening 건수를 구하였으며 정상치 이하에서의 재검기준도 설정하여 비교하였다. 결과 : 1차 screening 건수 백분율은 30~40%의 결과를 얻었고, 2차 screening 건수 백분율은 AFP 26.1%, CEA 18.9%, CA19-9 17.3%, CA-125 18.7%, PSA 21.0%로 평균 20%의 screening 백분율을 얻었다. 정상치 이하에서의 재검기준은 AFP 5.0이하$\leftrightarrow$10.0이상, CEA 1.0이하$\leftrightarrow$3.0이상, 2.0이하$\leftrightarrow$4.0이상, CA19-9와 CA-125 10.0이하$\leftrightarrow$30.0이상, PSA 1.0이하$\leftrightarrow$2.0이상으로 정하였으며 평균 20.4%의 screening 백분율에 재검기준을 적용시켜 실제 재검사 건수를 얻었다. 2달 동안 재검사 건수는 AFP 0건, CEA 15건, CA19-9 3건, CA-125 2건, PSA 5건이었다. 결론 : OCS QC 프로그램을 이용하여 시스템적인 재검기준을 마련함으로 검사자간 재검 실시 편차의 감소가 있었고 정상치 이하 값에서 결과보고오류에 대해 개선이 있을 것으로 사료된다.

• International Journal of Fluid Machinery and Systems
• /
• 제6권3호
• /
• pp.152-159
• /
• 2013

A two-dimensional Darrieus-type hydroturbine system, installed with a wear for flow streams such as small rivers and waterways, has been developed for hydropower utilization of extra-low head less than 2m. There are several problems such as flow rate change and flowing wastes to be solved for its practical use in natural flow streams. In the present study, at first, a design guideline in the case of overflow or bypass flow is shown by using simple flow model. Next, in order to avoid the unexpected obstacles flowing into the hydroturbine, an installation of waste screening system is examined. It is confirmed that the screen is effective with some amount of bypass flow rate, however the output power is remarkably deteriorated.

• 환경영향평가
• /
• 제10권3호
• /
• pp.195-209
• /
• 2001

The objective of this study is intended to propose plans for reforming environmental impact assessment(EIA) systems by reviewing the current legal systems of EIA related laws and their implementation status in Korea, and by comparing the Korean situation to EIA systems in several foreign countries. This study tried to integrate all EIA related systems scattered over several laws into one comprehensive EIA law, and also to develop legal procedures necessary to accomplish the legislative purpose of the integrated EIA law. Therefore, I propose four reforms (1) All EIA systems should be integrated into one comprehensive EIA act. (2) Administrative plans and policies, though environmentally harmful, which are not currently subject to any prior consultation system, should be covered by the prior consultation system. (3) A screening or scoping should be adopted. (4) Widen civil participation should be encouraged and the administrative control enforcement and introduction of group litigation or citizen suits would be considered.

• 센서학회지
• /
• 제13권6호
• /
• pp.454-461
• /
• 2004

We have designed a portable electronic nose (e-nose) system using an array of commercial gas sensors and personal digital assistants (PDA) for the recognition and analysis of volatile organic compounds (VOC) in the field. Field screening of pollutants has been a target of instrumental development during the past years. A portable e-nose system was advantageous to localize the special extent of a pollution or to find pollutants source. The employment of PDA improved the user-interface and data transfer by Internet from on-site to remote computer. We adapted the Lavenberg-Marquardt algorithm based on the back-propagation and proposed the method that could predict the concentration levels of VOC gases after classification by separating neural network into two parts.

• BMB Reports
• /
• 제54권1호
• /
• pp.59-69
• /
• 2021

The ability to read, write, and edit genomic information in living organisms can have a profound impact on research, health, economic, and environmental issues. The CRISPR/Cas system, recently discovered as an adaptive immune system in prokaryotes, has revolutionized the ease and throughput of genome editing in mammalian cells and has proved itself indispensable to the engineering of immune cells and identification of novel immune mechanisms. In this review, we summarize the CRISPR/Cas9 system and the history of its discovery and optimization. We then focus on engineering T cells and other types of immune cells, with emphasis on therapeutic applications. Last, we describe the different modifications of Cas9 and their recent applications in the genome-wide screening of immune cells.

• 전력전자학회논문지
• /
• 제27권3호
• /
• pp.265-274
• /
• 2022

This paper proposes a machine learning-based screening algorithm to build the retired battery pack of the energy storage system. The proposed algorithm creates the dataset of various performance parameters of the retired battery, and this dataset is preprocessed through a principal component analysis to reduce the overfitting problem. The retried batteries with a large deviation are excluded in the dataset through a density-based spatial clustering of applications with noise, and the K-means clustering method is formulated to select the group of the retired batteries to satisfy the deviation requirement conditions. The performance of the proposed algorithm is verified based on NASA and Oxford datasets.