• 품질경영학회지
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• 제41권4호
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• pp.673-681
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• 2013

Purpose: The purpose of this study is to investigate the design optimization modeling of screening procedures based on the assessment of misclassification errors. Methods: Misclassification errors due to measurement variability are derived for normally distributed quality characteristics. Further, an optimization model for ensuring the level of outgoing quality is proposed and demonstrated through an illustrative example. Results: It is shown that two types of misclassification errors (i.e., false acceptance and false rejection) may be properly compromised through an analytical assessment of measurement errors and an optimization modeling. It is also discussed that a variety of optimization modeling may be enabled based on the derivation of measurement errors. Conclusion: It may be concluded that the design of screening inspection may further be facilitated by including the effect of measurement errors on the performance of screening inspection procedure.

• Nuclear Engineering and Technology
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• 제47권2호
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• pp.187-195
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• 2015

Human-induced initiating events, also called Category B actions in human reliability analysis, are operator actions that may lead directly to initiating events. Most conventional probabilistic safety analyses typically assume that the frequency of initiating events also includes the probability of human-induced initiating events. However, some regulatory documents require Category B actions to be specifically analyzed and quantified in probabilistic safety analysis. An explicit modeling of Category B actions could also potentially lead to important insights into human performance in terms of safety. However, there is no standard procedure to identify Category B actions. This paper describes a systematic procedure to identify Category B actions for low power and shutdown conditions. The procedure includes several steps to determine operator actions that may lead to initiating events in the low power and shutdown stages. These steps are the selection of initiating events, the selection of systems or components, the screening of unlikely operating actions, and the quantification of initiating events. The procedure also provides the detailed instruction for each step, such as operator's action, information required, screening rules, and the outputs. Finally, the applicability of the suggested approach is also investigated by application to a plant example.

• 환경정책연구
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• 제10권1호
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• pp.129-150
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• 2011

본 논문은 현행 환경평가 제도가 평가 대상을 규모 기준으로 규정함으로써 발생되는 비효율성을 개선하기 위해 스크리닝의 도입을 통한 환경평가 절차 효율화 방안을 제안하였다. 대상사업은 환경적 영향이 미미한 소영향 사업으로 한정하였다. 우선, 국내에서 추진되었던 절차 효율화 사례 등을 살펴보고 그 특징 및 한계점을 도출하였다. 또한 사업의 특성 및 환경적 영향을 고려하여 후속 환경평가 실시여부와 그 정도를 개별적으로 판단하는 평가 대상 선별과정인 스크리닝의 국내 도입 가능성을 검토하였다. 외국의 스크리닝 제도 및 그 시사점 분석을 통해 국내 적용 가능한 스크리닝 도입 시나리오 제시를 통해 절차 효율화를 도모하고자 하였다. 소영향 사업들에 대해 환경평가 현황 및 소영향 사업들의 특징을 분석하여 스크리닝의 도입 필요성과 가능성을 확인한 후 절차 효율화 방안을 제시하였다. 본 연구에서 제안하는 개선 방안은 소영향 사업에 대해 환경영향평가 실시를 면제하여 줄 수 있는 스크리닝 절차의 도입이다. 이는 규제완화의 효과 및 평가기간과 협의기간의 단축을 기대할 수 있다. 또한, 사업자들에게 스크리닝을 통한 평가절차 간소화 기회를 제공하여 계획 초기 단계에서부터 친환경적 계획 수립을 위해 노력하도록 유도하여 계획기간의 단축까지 기대할 수 있다. 즉, 사업자의 자율적인 노력을 도모하고 스크리닝으로 평가 절차를 생략하는 대신 저감대책 반영 여부에 대한 승인기관의 확인을 강조하여 사업자와 승인기관의 책임의식을 강화시킬 수 있는 방안이 될 수 있다.

• 농약과학회지
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• 제5권3호
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• pp.41-46
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• 2001

분지아미노산 생합성 과정에 관여하는 첫 번째 효소인 acetolactate synthase (ALS)를 대상으로 수행할 수 있도록 고효율 검색방법(High Throughput Screening, HTS)을 개발하였고, 이를 이용하여 식물특이적 효소 저해제로 알려진 107개의 기존 화합물 중에서 새로운 ALS 저해 화합물을 선발하였다. 기존의 방법과 비교할 경우 한사람이 1회 수행한다고 하면 8 배 효율이지만 연속적으로 수행한다고 할 경우 1/10 이하의 양, 동일한 재료의 적용, 측정 결과의 계산, enzyme kinetics 등을 감안하면 최소 100 배 이상의 효과를 얻을 수 있다. 새로운 ALS 저해제로 탐색된 화학물질은, ammooxyacetic acid, azelaic acid, citric acid, cyanuric fluoride, glyoxylic acid, itaconic acid, malonic acid, niclosamid, oxalic acid, 2-oxoglutaric acid, suramin 등이었다. 앞으로 이들을 기본 구조로 하여 신규 ALS 저해 제초제의 개발을 위한 유도체의 합성에 이용되었으면 한다.

• 대한산업공학회지
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• 제43권2호
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• pp.127-134
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• 2017

For product or process design and development, it is common to optimize multiple responses (characteristics) based on experimental data. To determine optimal conditions, we need to design the experiment, estimate a proper model for each response, and optimize the multiple responses simultaneously. There are several techniques and many research results on optimizing multiple responses simultaneously, when the experimental data are available. However, the experimental design issue for optimizing multiple responses has not been discussed yet. This paper proposes some idea on how to plan screening design when requirements for multiple performance characteristics are to be met in developing new products. A screening design procedure is developed for securing the requirements of multiple responses. Initial design factors are classified into three categories; specific, non-conflicting common, and conflicting common. After screening experiments, follow-up design region search method is suggested with respect to the most unsatisfied or important response, or overall desirability. A case study on a synthesis of melamine formaldehyde resin is presented to illustrate the procedure and to show the validity of the approach.

• 대한전기학회:학술대회논문집
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• 대한전기학회 1999년도 하계학술대회 논문집 B
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• pp.871-873
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• 1999

According to the reports about the failure mode analysis of modules and systems, It is said that there are many early failure of system. To remove latent defects which causes early failures like that, It is necessary that screening test is performed. ESS is often used fur screening electronic equipments, and is proposed by the most powerful tool for removing latent defects of electronic equipments. [1][2] In this report, the procedure of the environmental stress screening which uses the temperature cycling stress is proposed. It is considered about environmental conditions of distributed control system(DCS) to be tested, design specifications of the system, recommended conditions of relative IEC-STD and applied conditions of similar company. ESS test was applied at the DCS to be installed in power plant. As the results of analyzing discovered problems. It was found that almost latent defects of electronic control systems was discovered early.

• Earthquakes and Structures
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• 제16권1호
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• pp.29-39
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• 2019

A three-step screening process is presented in this article for selection of consistent earthquake records in which number of suitable ground motions is quickly screened and reduced to a handful number. Records that remain at the end of this screening process considerably reduce the dispersion of structural responses. Then, an effective method is presented for spectral matching and modification of the selected records. Dispersion of structural responses is explored using different statistical measures for each scaling procedure. It is shown that the Uniform Design Method, presented in this study for scaling of earthquake records, results in most cases in the least dispersion measure.

• 대한산업공학회지
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• 제26권3호
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• pp.200-205
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• 2000

An economic process monitoring procedure is presented using a surrogate variable for the case where performance variable is dichotomous. Every item is inspected with a surrogate variable and determined whether it should be accepted or rejected. When an item is rejected, the previous number of consecutively accepted items is compared with a predetermined number r to decide whether there is a shift in fraction nonconforming or not. The conditional distribution of the surrogate variable given the performance variable is assumed to be normal. A cost model is constructed which includes costs of inspection, misclassification, illegal signal, undetected out-of-control state, and correction. Methods of finding the optimum number r and screening limit are provided. Numerical studies on the effects of cost coefficients are also performed.

• Asian Pacific Journal of Cancer Prevention
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• 제15권2호
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• pp.589-594
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• 2014

Few studies have examined reasons why those with low socioeconomic status do not adequately receive cancer screening. We therefore conducted a qualitative study to assess the barriers to cancer screening in people with low socioeconomic status, and to examine the reasons why Medical Aid Program (MAP) recipients do not participate in the National Cancer Screening Program (NCSP). A focus group methodology was used. Participants included MAP recipients (men aged 45-79 years, women aged 35-79 years) who had been invited to cancer screening at least twice based on the NCSP protocol, but had not been screened for any cancer from 2009-2012. We recruited participants living in the cities of Goyang and Paju. A total of 23 MAP recipients participated in four focus group discussions, including 12 men and 11 women. In this qualitative study, we identified six barriers to screening: lack of trust in the NCSP and cancer screening units; fear of being diagnosed with cancer; discomfort or pain from the screening procedure; lack of time, lack of knowledge about cancer screening or lack of awareness of the existence of the NCSP; physical disability or underlying disease; and logistic barriers. Interventions such as individualized counseling, letters and reminders, or other individually-targeted strategies, especially for those with lower socioeconomic status are required to increase participation and reduce disparities in cancer screening.

• 한국작물학회지
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• 제46권4호
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• pp.284-288
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• 2001

Water deficit is a serious constraint to soybean [Glycine max L. (Merr.)] production in rainfed regions of Asia, Africa, and America. This study was conducted to develop a simple and effective screening method for drought tolerance in soybean. Fifteen soybean cultivars, eight identified to be drought-tolerant and seven drought-sensitive in previous studies, were used for the evaluation of drought tolerance under the new screening conditions. The seedling screening method was consisted of a treatment in a PEG solution and drought treatment in parafilm-layered pots. 5-day-old seedlings were treated in a 18% PEG solution for 4 days and their wilting and hypocotyl browning were recorded. Three seedlings grown in a parafilm-layered pot containing peat moss were drought-stressed by withholding water from the third day after seedling emergence, and root and seedling growth were examined. Degree of drought tolerance were rated based on seedling vigor in the PEG solution and drought-stressed parafilm-layered pots, and also on the penetration ability of roots through parafilm layer. Most of seedlings of the drought-tolerant cultivars showed higher vigour and root penetration than those of the drought-sensitive cultivars under the new screening conditions. Our results indicate that the new method can be used as a simple and effective screening procedure for drought tolerance in soybean breeding programs.