• Journal of Scientific & Technological Knowledge Infrastructure
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• s.2
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• pp.100-101
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• 2000

최근 분자모델링을 이용한 신물질설계기술 (Computer Aided Material Design)이 재료과학이나 생명과학분야의 획기적인 성공사례를 통하여 신물질개발연구에 실제적인 도움을 줄 수 있는 매우 효율적인 방법이라는 인식이 보편화되었다. 최근 미국, 유럽 등 기술선진국에서는 신제품 개발시 기존의 실험적인 연구가 아닌 모델링 방법의 분자설계기술을 이용하여 신약이나 기능성 첨단소재 등의 개발로 엄청난 부가가치를 창출하고 있다. 과학적 기반이 열세이고, 사업기술의 수준이 상대적으로 중간적 지위에 있는 우리나라는 신물질 및 신제품 개발을 위한 첨단기반기술의 확보가 다가오는 21세기 국가산업경쟁력 제고에 필수적이라는 인식 아래 분자설계 개발연구센터는 산업자원부의 기술혁신센터(Technology Innovation Center)로 지정받아 컴퓨터 모델링을 이용한 화학신소재 분차설계기술 보급에 힘쓰고 있다. 산업체에 첨단기술 보급을 위하여 기술혁신센터를 운영하고 있으며 또한, 초고속정보망기술지원실에서 정보통신부의 지원으로 올해 '3차년도 초고속응용기술지원사업'을 수행하고 있는 숭실대학교 분자설계연구센터의 소장인 노경태 교수를 찾아보았다.

• International Journal of Computer Science & Network Security
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• v.22 no.11
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• pp.93-100
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• 2022

The use of innovative technologies is one of the promising areas of education development, so the article clarifies the content of the terms "innovation" "pedagogical technology". Our goal is to justify the need to use innovative technologies in education. Innovative technologies are divided into four groups, depending on the appropriate form of educational activity for their use. The development of innovative pedagogical technologies at the present stage of education development should be carried out in accordance with the criteria of technological efficiency, which are presented in the article: scientific; systematic; guaranteed; manageable; mass. Based on the analysis of the process of formation of pedagogical education, the main trends in the information support of teachers in the system of pedagogical education were revealed. Its theoretical and methodological foundations were determined, promising directions and main ways of improving the information support of teachers' education as an organic component of continuous pedagogical education in Ukraine were justified. The conducted study of the state of information support for teachers allowed us to establish that the main functions of scientific and pedagogical information - analytical and predictive, integrative, operational and purposeful informing of various categories of specialists - teachers-are not being implemented enough. This is due to the versatility and complexity of the pedagogical process, the low level and limited range of development of systems of operational differentiated scientific and methodological services for various categories of teachers. Ways to improve the information function of teacher education are determined.

• Journal of Information Management
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• v.36 no.3
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• pp.167-182
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• 2005

This study is to provide the customer's satisfaction and the economic evaluation model for the KISTI S&T Informaion Analysis Report with the results of the survey. Recently the important issue for the informaion analysis service is make policies that reflect the proper demand and satisfaction of customers. In this paper, we explain how the evaluate of information analysis service in the customer's satisfaction and the economic valuation model can be estimated using survey. In such a setting, the customer's satisfaction and the economic evaluation model are important methods for the reflection of monitored information in national scientific and technological policies.

• International Journal of Advanced Culture Technology
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• v.9 no.3
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• pp.34-45
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• 2021

On February 18, 2019, the Chinese government officially released the Outline of the Development Plan for the Guangdong-Hong Kong-Macao Greater Bay Area, which will lead the country in a new round of reform and opening-up. The Greater Bay Area will become a dynamic world-class city cluster, an international scientific and technological innovation center with global influence, an important support for the development of the "One Belt And One Road", a demonstration area for in-depth cooperation between the mainland and Hong Kong and Macao, and a high-quality living area for living, working and traveling. Non-Pearl River Delta(Non-PRD) cities in Guangdong Province are adjacent to the Guangdong-Hong Kong-Macao Greater Bay Area, so it is of practical significance to promote the high-quality development of urban tourism from an international perspective. Based on the panel data released in Guangdong Yearbook 2019, this paper uses the envelopment data analysis (DEA) method to explore ways to promote the high-quality tourism development of Non-PRD cities in Guangdong Province based on the perspective of international development.

• Journal of Technology Innovation
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• v.22 no.4
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• pp.89-116
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• 2014

Socially-oriented R&D programs aimed at solving societal problem rather than scientific and industrial fruits have started recently. Societal problem is recognized as dilemma since this problem related to various stakeholders. And this is not solved with single program and needed long-term process. So the perspective of socio-technical system transition including technological and institutional change is needed. This paper suggests policy implication of Socially-oriented R&D programs from socio-technical system transition perspective. 'Transitioning of Socially-oriented R&D program' is the key concept of restructuring the program for the system transition. The establishment of multi-layer transition governance and the transition vision-making and transition experiment planning are the key process of transitioning the R&D program. This paper suggests the ways and issues of implementing this process in Socially-oriented R&D program.

• Economic and Environmental Geology
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• v.53 no.1
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• pp.111-120
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• 2020

Remarkable scientific and technological achievements are mainly shown in the 'super-convergence' or 'convergence of convergence' among cross- disciplinary fields, and advanced countries are promoting the 'high-risk, high-return research' ecosystem. Google LLC is carrying out numerous new challenges in terms of a non-failure perspective. Innovative research by the US Defense Advanced Research Projects Agency (DARPA) has produced such breakthroughs as the Internet, GPS, semiconductors, the computer mouse, autonomous vehicles, and drones. China is pioneering a 'Moon Village' and planning the world's largest nuclear fusion energy and ultra-large particle accelerator project. Japan has also launched 'the moonshot technology development research system' to promote disruptive innovation. In Korea, the government is preparing a new research program to tackle the global scientific challenges. Therefore, it is necessary to determine the reasonable geoscientific challenges to be addressed and to conduct a preliminary study on these topics. For this purpose, it is necessary to conduct long-term creative research projects centered on young researchers, select outstanding principal investigators, extract innovative topics without prior research or reference, simplify research proposal procedures, innovate the selection solely based on key ideas, and evaluate results by collective intelligence in the form of conferences.

• Korea Science and Art Forum
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• v.16
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• pp.157-169
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• 2014

Lake Biwa Canal was a dream project that reminds us the passion and innovation of Kyoto Citizens more than water supply. It is a modernization project combining engineering knowledge and scientific technology, which started transportation by ship through big-scale civil construction as well as supplying electricity as the first waterpower plant in Japan, and it overcame the physiographic limit through adopting unique method of waterway transportation. Lake Biwa Canal, which has tangible and intangible culture heritage value as the traditional space of Kyoto, the Old Capital of 1200 years, conceives a cultural meaning that is connected through various mutual relation as well as scientific technologic factor. Lake Biwa Canal is not only the function for supplying water to gardens and temples of Kyoto region, but it is also a cultural fruit that is formed by complex causal relationship of various contents such as geographical and environmental background, the phases of the times, local development policy, political circumstances and religions. This study is aimed at interpreting the value of Lake Biwa Canal multilaterally by the convergence of cultural and technological aspects through the view of the world which the age tried to pursue, focusing on the construction of Lake Biwa Canal which was accomplished in the process of promoting the modernization of Kyoto.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.4
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• pp.1807-1810
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• 2014

Background: It is known that inducible nitric oxide synthase (iNOS)/nitric oxide (NO) plays an integral role during intestinal inflammation, an important factor for colon cancer development. Natural compounds from Curcuma longa L. (Zingiberaceae) have long been a potential source of bioactive materials with various beneficial biological functions. Among them, a major active curcuminoid, demethoxycurcumin (DMC) has been shown to possess anti-inflammatory properties in lipopolysaccharide (LPS)-activated macrophages or microglia cells. However, the role of DMC on iNOS expression and NO production in an in vitro inflamed human intestinal mucosa model has not yet been elucidated. This study concerned inhibitory effects on iNOS expression and NO production of DMC in inflamed human intestinal Caco-2 cells. An in vitro model was generated and inhibitory effects on NO production of DMC at 65 ${\mu}M$ for 24-96 h were assessed by monitoring nitrite levels. Expression of iNOS mRNA and protein was also investigated. DMC significantly decreased NO secretion by 35-41% in our inflamed cell model. Decrease in NO production by DMC was concomitant with down-regulation of iNOS at mRNA and protein levels compared to proinflammatory cytokine cocktail and LPS-treated controls. Mechanism of action of DMC may be partly due to its potent inhibition of the iNOS pathway. Our findings suggest that DMC may have potential as a therapeutic agent against inflammation-related diseases, especially in the gut.

• International Journal of Advanced Culture Technology
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• v.11 no.4
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• pp.310-316
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• 2023

This study aims to predict uncertain future scenarios that may unfold in South Korea in the near future, utilizing the theory of extreme events(X-events). A group of 32 experts, consisting of government emergency planning officers, was selected as the focus group to achieve this objective. Using the Focus Group Interview (FGI) technique, opinions were gathered from this focus group regarding potential X-events that may occur within the advanced science and technology domains over the next 10 years. The analysis of these opinions revealed that government emergency planning officers regarded the "Obsolescence of current technology and systems," particularly in the context of cyber network paralysis as the most plausible X-event within science and technology. They also put forth challenging and intricate opinions, including the emergence of new weapon systems and ethical concerns associated with artificial intelligence (AI). Given that X-events are more likely to emerge in unanticipated areas rather than those that are widely predicted, the results obtained from this study carry significant importance. However, it's important to note that this study is grounded in a limited group of experts, highlighting the necessity for subsequent research involving a more extensive group of experts. This research seeks to stimulate studies on extreme events at a national level and contribute to the preparation for future X-event predictions and strategies for addressing them.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.26 no.1
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• pp.64-69
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• 2022

Commercialization of public technology is the transfer of government-led scientific and technological innovation and R&D results to the private sector, and is recognized as a key achievement driving economic growth. Therefore, in order to activate technology transfer, various machine learning methods are being studied to identify success factors or to match public technology with high commercialization potential and demanding companies. However, public technology commercialization data is in the form of a table and has a problem that machine learning performance is not high because it is in an imbalanced state with a large difference in success-failure ratio. In this paper, we present a method of utilizing CTGAN to resolve imbalances in public technology data in tabular form. In addition, to verify the effectiveness of the proposed method, a comparative experiment with SMOTE, a statistical approach, was performed using actual public technology commercialization data. In many experimental cases, it was confirmed that CTGAN reliably predicts public technology commercialization success cases.