• 약학회지
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• 제53권5호
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• pp.293-297
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• 2009

The abuse of methamphetamine (MA) is one of the most serious drug abuses in Asia. And, the prevention of precursor production for abuse drug is one of the most effective drug control system. Isotope ratio analysis at natural abundance levels have been used to establish the environmental source or the geographic origin of various biological and nonbiological materials. Ephedrine, the precursor of MA, is produced by one of three methods; extraction from Ephedra plants, full chemical synthesis or via a semi-synthetic process involving the fermentation of sugar, followed by amination. We investigated the origin of ephedrine and pseudoephedrine based on the carbon and nitrogen values for nineteen pharmaceutical powder materials (PPMs) obtained from pharmaceutical company in Korea by stable isotope ratio mass spectrometry coupled to an elemental analyser (EA-IRMS). The carbon delta values for the ephedrine and pseudoephedrine were -24.21~-22.72 (mean=-23.72) $^{\cir}/_{\circ\circ}$ and -23.79~-22.71 (mean=-23.48) $^{\cir}/_{\circ\circ}$. The nitrogen delta values were 3.51~5.55 (4.43) $^{\cir}/_{\circ\circ}$ and 2.24~8.22 (5.42) $^{\cir}/_{\circ\circ}$. These results indicate that PPMs are semi-synthetic products. Therefore the origins of ephedrine(natural, semi-synthetic or synthetic) could be discriminated by using carbon and nitrogen stable isotope ratios. we are sure tat this stable isotope ratio analysis can discriminate the origins of precursors of methamphetamine.

• 한국측량학회:학술대회논문집
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• 한국측량학회 2007년도 춘계학술발표회 논문집
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• pp.317-321
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• 2007

"The project for production of medium classification landcover maps using satellite images" has been completed from 1998 until 2005 in Korea. As the 5th project was finished in 2005, medium classification landcover maps for all areas of South Korea have been produced. The products of project currently is used in lots of fields such as public governments, universities and research institutes for policy application and scientific research. But final results of the project have several problems which is insufficiency of reliability, discordance of classification codes and many others because each project was progressed year by year. In this study, problems of existing production methods about medium classification landcover maps are extracted and solution of problems is offered. Therefore, this study will make it possible to efficiently produce and update medium classification landcover maps.

• 한국환경농학회지
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• 제9권1호
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• pp.61-68
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• 1990

The pressure to develop new agricultural technologies will be roughly proportional to the rate of depletion of natural resources employed in agriculture. Of these resources, land, water and gentic resources are critical. The development of agriculture is associated with a scientific and technological establishment, of remarkable capability ; responding rapidly to many problems encountered by the agricultural production. These advantages are also coupled with constraints. Agricultural systems are concerned with the efficient conversion of resources into products that are wanted by the producer or someone else who is prepared to pay for them. They are based on biological processes, but they are operated by the people for a multiplicity of purposes. Study of agricultural systems is aimed at helping in the operation of systems, their repair or their improvement. The future concerns of agriculture will center on (1) increasing and safeguarding the supplies of productive inputs to agriculture, (2) improving the efficiency with which these inputs are used in food production, (3) developing new sources of basic food materials, and (4) coping with the external costs that tend to appear in intensive, mechanized agriculture.

• Genomics & Informatics
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• 제11권1호
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• pp.7-14
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• 2013

As the International Human Epigenome Consortium (IHEC) launched officially at the 2010 Washington meeting, a giant step toward the conquest of unexplored regions of the human genome has begun. IHEC aims at the production of 1,000 reference epigenomes to the international scientific community for next 7-10 years. Seven member institutions, including South Korea, Korea National Institute of Health (KNIH), will produce 25-200 reference epigenomes individually, and the produced data will be publically available by using a data center. Epigenome data will cover from whole genome bisulfite sequencing, histone modification, and chromatin access information to miRNA-seq. The final goal of IHEC is the production of reference maps of human epigenomes for key cellular status relevant to health and disease.

• 기술혁신학회지
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• 제7권1호
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• pp.42-63
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• 2004

Recent trend of rapid growth in the basic research activities in East-Asian newly industrialized countries bring about the change in the world knowledge production structure. Particularly, Korea showed the changing patterns not only in the number of publication, but also in the aspect of structural change of basic research activities. The stylized facts of basic research activities in Korea can be summarized in three aspects; first, selective development patterns, second, reverse pattern of evolution, and finally, the rapid growth of basic research activities in major firms. This paper analyse the evolutionary patterns of basic research activities in empirical base and propose the policy implication for supporting basic research activity in newly industrializing countries.

• Nuclear Engineering and Technology
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• 제53권8호
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• pp.2761-2766
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• 2021

A method for preparing "reagent" for radioactive methyliodide vapors production using an isotopic exchange reaction has been developed. Based on the obtained data of the isotopic exchange efficiency and hydraulic resistance, white fused alumina (700-840 ㎛) was selected as the carrying agent material for "reagent" production. The radioiodine isotopic exchange dependences on such parameters as temperature, gas flow velocity, and the methyliodide concentration in it were determined. Optimal conditions have been selected to achieve 85% of the isotopic exchange rate in 1 h of the experiment. The obtained data allowed to develop an approach to the test of iodine filters for nuclear power plants and to determine their efficiency.

• 한국정밀공학회지
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• 제11권1호
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• pp.211-218
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• 1994

Grinding is considered as a very effective machining technology to attain high production rates and a good surface quality of hard and brittle components. However, the grinding operations till needs the skill and the experience of an operator because of a lack of scientific knowledge and engineering principles. This is the reason why grinding operations are not completley intergrated in CIMS(Computer Intergrated Manufacturing System. Recent develop- ment focus on expert system which deals with domain specific knowledge in order to solve this problem. Firstly, in this study, a basic strategy to develop the grinding knowledge-base for grinding is discussed. Next, the architecture of knowledge-base and management of the grinding knowledge-base(GKB) is described.

• 수산해양기술연구
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• 제52권2호
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• pp.111-120
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• 2016

Acoustic surveys using a scientific echosounder and trawl surveys were concurrently carried out in between Geoje and Tongyeong of the South Sea by season. The anchovy schools were identified by trawling in each station and used for frequency response analysis. Frequency responses of anchovy schools by season and species composition ratio were examined using multi-frequencies (18, 38, 70, 120 and 200 kHz). The frequency response r(f), is one of the acoustic characteristics which means the volume back-scattering strength ratio between a reference frequency and other frequencies. In spring, the r(f) of anchovy schools decreased with increased frequency, with the exception of 120kHz. While, in winter, the r(f) continuously decreased inversely proportional to the increase in frequency. Frequency response of anchovy schools presented a distinctive difference between spring and winter, however it did not different in spife of different species composition ratios in schools.

• 대한지리학회지
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• 제50권6호
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• pp.641-657
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• 2015

오늘날 대학, 기업, 공공연구기관 사이의 연구협력은 과학 기반 기술 혁신과 연관되어 주요 정책 현안이 되고 있다. 본 연구는 지난 10년(2002~2012) 동안 7개의 과학 기반 기술에서의 한국인 과학자와 연구자들이 참여하여 세계의 주요 과학 저널에 발행된 공동저술 논문을 조사하여 연구협력의 공간적 패턴을 탐구한다. 공동 저자의 소속 기관과 그 위치 정보를 제공하는 공동저술 논문을 연구협력의 지표로 이용하여 국내와 국제적 스케일에서 여러 형태의 협력 패턴과 추세를 기술하였다. 지난 10년 동안 공저 논문의 수와 참여 공저자의 수가 크게 증가하면서 과학적 연구협력이 공간적으로 분산하는 증거가 뚜렷이 확인되었다. 국내 연구협력의 분산 추세에도 불구하고 지식 흐름이 혁신 중심 지역에 편향되며, 지역 내에서 과학적 지식 생산이 국지화하는 증거도 발견되었다.

• 대한본초학회지
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• 제28권5호
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• pp.13-19
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• 2013

Objectives : The purpose of this study is correct the scientific name of Aquilariae Lignum in Korean Herbal Pharmacoepia. Methods : The production areas of Aquilariae Lignum and its trading status with China in Chinese history, Sanscrit-Chinese Translation Sutra, Naming year and the discovered district in main Aquilaria spp., Several nation's Pharmacoepia, The Plant List(TPL), Convention on International Trade in Endangered Species of Wild fauna and flora(CITES) and The International Union for Conservation of Nature(IUCN) were cross-checked. Results : The records in the Jiaozhouyiwuzhi written in the early 2nd century said that Aquilariae Lignum was produced in Vietnam. NanfangCaomuZhuang written in 304 said that Agarwood in Vietnam had white flowers. Vietnam had led production and trading of Aquilariae Lignum until Qing Dynasty. Aquilariae Lignum from Malaysia and Indonesia was not traded with China. In Sanscrit-Chinese Translation Sutra, India Aquilariae Lignum was translated as Vietnam Aquilariae Lignum. Aquilaria malaccensis was discovered from Malay-Peninsular in 1783, and has green or dirty yellow flowers. A. agallocha from North-Eastern India in 1814, white flowers. A. crasssna from Vietnam in 1914, white flowers. A. crassna is different from A. malaccensis in several ways, such as flower, fruit, seed and disribution. In several Nation's Pharmacoepia, A. crassna was a synonym of A. agallocha. But in TPL, CITES and IUCN, A. malaccensis was an accepted name, and A. agallocha was a synonym of A. malaccensis. Conclusions : These results show that the original species of Aquilariae Lignum in Korea Herbal Pharmacoepia should be reversed from A. agallocha to A. crassna Pierre ex Lacomte.