• 제목/요약/키워드: Science major

검색결과 18,794건 처리시간 0.042초

정상인과 요추 추간판 탈출증 환자에서 구두 뒷굽 높이에 따른 요추전만도의 변화 (Changes of Lumbar Lordosis According to Different Heel Heights in Normal Adults and Patients with HNP)

  • 문동철;권영실;송주영;남기원;송주민;김동현;백수정;구현모;최진호;김진상
    • The Journal of Korean Physical Therapy
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    • 제13권2호
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    • pp.467-475
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    • 2001
  • The purpose of this study was to evaluate changes of static lumbar lordosis by different heel heights in normal adults and patients with herniation of nucleus pulposus(HNP). The lumbar lordosis was examined while standing on barefoot, on heel support with 4cm heel, and with 8cm heel in 10 normal adults and 10patients with HNP. Standing lumbar lateral view was performed by 20 minutes adaptation with corresponding shoe types. The angle of lumbar lordosis was taken with Wiltse and Winter's method(angles between upper margin of 1 st lumbar body and upper margin of 5th lumbar body). The results of this study were as follow: 1. Significant statistical decrease in lumbar lordosis was observed as heel heights were increased from barefoot to 8cm high heel in normal adults(p<0.05). 2. There were no significant differences in lumbar lordosis according to three different heel heights in patients with HNP(p>0.05). 3. In comparison of barefoot, There were statistically significant decrease in HNP patients compared with normal adults in terms of lumbar lordosis(p<0.05).

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혈관내피세포에서 TNF-α로 유도되는 혈관염증에 대한 쏙(Upogebia major) 효소가수분해물의 억제 효과 (Inhibition Effect of Enzymatic Hydrolysate from Japanese Mud Shrimp Upogebia major on TNF-α-induced Vascular Inflammation in Human Umbilical Vein Endothelial Cells (HUVECs))

  • 김소연;양지은;송재희;맹상현;이지현;윤나영
    • 한국수산과학회지
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    • 제51권2호
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    • pp.127-134
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    • 2018
  • Arteriosclerosis is the major cause of coronary artery and cerebrovascular disease, which are leading causes of death. Pro-inflammatory cytokines induce injury to vascular endothelial cells by increasing cell adhesion molecules, leading to vascular inflammation, a major risk factor for the development of arteriosclerosis. In the current study, we investigated the inhibitory effect of enzymatic hydrolysate from Japanese mud shrimp Upogebia major on the inflammation of tumor necrosis $factor-{\alpha}$ ($TNF-{\alpha}$)-stimulated human umbilical vein endothelial cells (HUVECs). We first evaluated the antioxidant and angiotensin I-converting enzyme (ACE) inhibitory activities of eight U. major enzymatic hydrolysates: alcalase, papain, ${\alpha}$-chymotrypsin (${\alpha}-Chy$), trypsin, pepsin, neutrase, protamex and flavourzyme. Of these, ${\alpha}-Chy$ exhibited potent antioxidant and ACE inhibitory activities. The ${\alpha}-Chy$ hydrolysate was fractionated by two ultrafiltration membranes of 3 and 10 kDa. The ${\alpha}-Chy$ hydrolysate of U. major and its molecular weight cut-off fractions resulted in a significant reduction in NO production and a decrease in cell adhesion molecules [vascular cell adhesion molecule-1 (VCAM-1), intercellular adhesion molecule-1 (ICAM-1) and endothelial-selectin (E-selectin)] and pro-inflammatory cytokines [interleukin-6 (IL-6), interleukin-8 (IL-8) and monocyte chemoattractant protein-1 (MCP-1)] in $TNF-{\alpha}$-stimulated HUVECs. These results suggest that enzymatic hydrolysate from U. major can be used in the control and prevention of vascular inflammation and arteriosclerosis.

창의적 사고 계발을 위한 고등학교 학습 프로그램 개발: 태양계 축소 모형을 중심으로 (The Development of High School Instructional Program for Increasing Creative Thinking Abilities: Focused on Building a Scale Model of the Solar System)

  • 김은주;이효녕;윤일희;강천덕
    • 한국지구과학회지
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    • 제29권3호
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    • pp.290-304
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    • 2008
  • 이 연구의 목적은 고등학생들의 태양계 상대적인 크기를 쉽게 이해하고 창의적인 사고 능력을 키우기 위한 교육 프로그램 개발이다. 프로그램은 태양계의 상대적 크기 영역에서 4개 주제와 8차시 분량으로 개발되었다. 개발된 프로그램은 구미시에 소재한 G 고등학교 10학년 155명에게 투입하였다. 연구 결과를 살펴보면, 개발된 프로그램 학습을 통해 학생들이 태양계 행성들의 상대적인 크기를 쉽게 이해할 수 있었고, 발산적 사고로부터 수렴적 사고로 이어지는 창의적 사고력을 향상 시켰다. 개발된 프로그램의 주제별 활동을 통하여 학생들에게 창의적 사고 능력의 배양과 태양계내의 행성간 거리와 크기에 대해 쉽게 학습시킬 수 있을 것으로 기대된다.

슬링을 이용한 경부 안정화 운동이 만성 목통증환자의 넙다리뒤근 유연성에 미치는 영향 (Effects of Cervical Stabilization Exercise Using Sling on Hamstring Flexibility in Patients with Chronic Neck Pain)

  • 김승민;이재혁;김태영;정은동;윤범철
    • 정형스포츠물리치료학회지
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    • 제14권2호
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    • pp.33-44
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    • 2018
  • Purpose: The primary purpose of this study was to investigate the effects of cervical stabilization exercise (CSE) on hamstring flexibility in patients with neck pain. A secondary purpose of this study was to investigate the effects of cervical range of motion (CROM) and craniovertebral angle (CVA). Methods: This study was a single-blind, randomized, comparative trial. Twenty patients were allocated into either the cranio-cervical flexion exercise (CCFE) group or the CSE group. Before and after the intervention, we measured straight leg raise (SLR), popliteal angle (PA), CROM, and CVA in the sitting and standing positions. Fisher's exact test, the Mann-Whitney test, and Wilcoxon's signed-rank test were used to analyze our data. Results: Both groups showed significant improvements in the value of SLR, PA, cervical extension, cervical rotation, and CVA in the standing position (both, p<.05) after intervention. However, only the CSE group showed significant improvements in cervical right lateral flexion (z=-2.209; p<.01) and cervical left lateral flexion (z=-2.537; p<.05) after intervention. The CSF group showed more significant improvements in SLR, PA, both cervical lateral flexions, and both cervical rotations than the CCFE group. Conclusions: The results of this study will guide future research in identifying the effectiveness of CSE. In conclusion, it can be inferred that CSE has a positive effect on SLR, PA, CROM, and CVA in the standing position in patients with chronic neck pain.

Molecular characterization and expression of CD96 in red seabream (Pagrus major)

  • Won-Sik Woo;Kwang-Min Choi;Min-Soo Joo;Gyoungsik Kang;Kyung-Ho Kim;Ha-Jeong Son;Min-Young Sohn;Do-Hyung Kim;Chan-Il Park
    • Fisheries and Aquatic Sciences
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    • 제26권2호
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    • pp.97-104
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    • 2023
  • CD96 is a membrane-bound receptor discovered in humans in 1992 that is mainly present in natural killer cells and T cells derived from haematopoietic cells and performs immune functions. Based on the sequence of CD96 obtained from red seabream (Pagrus major), phylogenetic analysis with other species, infections of normal fish, Streptococcus iniae and red sea bream iridovirus (RSIV), and expression analysis was conducted using real-time polymerase chain reaction. Phylogenetic analysis showed the highest homology with Sparus aurata, and multiple sequence analysis confirmed the conservation of major domains between different fish species. Normal fish high expression results were confirmed in the head kidney, and spleen, which are the haematopoietic organs of the fish. High expression levels were confirmed in the gills, liver, spleen, and kidney on day three after RSIV infection. After S. iniae infection, high expression was confirmed in the gills and liver on day one, and high expression was confirmed in the spleen from 12 hours. These results show that PmCD96 functions as an immune gene in P. major and is considered a basic research case for CD96 in fish's hematopoietic organ immune system.

Allelic Distribution of OsPRR37, a Major Heading Date Gene in Korean Rice Cultivars

  • Hayeong Lee;Yurim Kim;Jiheon Han;Sieun Choi;Yeeun Jun;Hosun Chun;Soonhwa Kwak;Youngjun Mo
    • 한국작물학회:학술대회논문집
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    • 한국작물학회 2022년도 추계학술대회
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    • pp.225-225
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    • 2022
  • Rice is a major food crop consumed by approximately half of the world's population. Heading date is one of the major agronomic traits and has a wide impact on the productivity and quality of rice. Recently, shortening the growth period of rice through modulating heading date has been emphasized as one of the most effective strategies for reducing methane emissions from paddy fields. OsPRR37, a major heading date gene in rice, represses flowering under both short-day and long-day conditions. Plants carrying the loss-of-function alleles of OsPRR37 have been reported to flower approximately seven days and 20 days earlier than those carrying the functional alleles in short day and long day conditions, respectively. In this study, we investigated the nucleotide sequence variation existing in the exonic regions of OsPRR37 and catalogued the allelic distribution in 208 Korean rice cultivars. We used four sets of primers for amplifying and sequencing the eight exons of OsPRR37. As a result, two types of loss-of-function alleles and four types of functional alleles were found in 208 Korean rice cultivars. Interestingly, only three cultivars (Jinbuolbyeo, Jinseolchal, and Mimyeon) carried loss-of-function alleles while 205 carried functional alleles, indicating that OsPRR37 loss-of-function alleles have been used very rarely in Korean rice breeding programs. To generate useful information for the development of early-maturing rice cultivars, our future work will focus on analyzing the effect of different OsPRR37 alleles on heading date and other major agronomic traits.

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Acoustic Property and Hardness of Coatings for Musical Instruments with Various Coating Thicknesses

  • Hwang, Hyeon-Deuk;Lee, Byoung-Hoo;Choi, Jae-Hoon;Kim, Hyun-Joong;Chung, Woo-Yang
    • Journal of the Korean Wood Science and Technology
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    • 제34권2호
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    • pp.58-67
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    • 2006
  • The relationship between acoustic property and coating hardness of musical instruments was investigated using a sound level meter and a pendulum hardness tester. Urethane topcoat, oil stain, natural oil varnish, and UV-curable epoxy acrylate coatings were applied on four different substrates: Paulownia coreana, Pinus koraiensis, Castanea crenata var. dulcis and Pinus densiflora. The influence of the coating type on the acoustic properties was stronger than that of the substrate. In the case of an oil stain formed with tacky coating layer, the sound pressure level (SPL) and surface hardness decreased with increasing of coating thickness. In the other coatings, SPL decreased and hardness increased as the coating layer thickened. However, SPL began to increase again at coating thickness above $100{\mu}m$.