• Asian Pacific Journal of Cancer Prevention
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• v.16 no.1
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• pp.239-244
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• 2015

Background: One of the causes of acute leukemia can be exposure to certain chemicals such as pesticides. This study determined the relationship between exposure to pesticides and the occurrence of acute leukemia in Fars province, south of Iran. Materials and Methods: Between April 2011 and April 2013 in a case-control study conducted in Nemazee Hospital in Shiraz, Southern Iran; 314 subjects diagnosed with acute leukemia (94 pediatric cases and 220 adults) were enrolled to determine any correlation between exposure to pesticides and the occurrence. Controls (n=314) were matched by sex and age. Results: There was a history of exposure to pesticides among 85% of pediatric cases and 69% of their controls and 83% of adult cases and 75% of their controls while 87.5% of pediatric cases and 90% of adult cases reported exposure to intermediate and high doses of pesticides and among the controls, the exposure to low doses of pesticides was 70.5% and 65%, respectively. Exposure to indoor pesticides was seen among most of cases and controls. Being a farmer was at a significantly more increased risk of developing acute leukemia in comparison to other jobs, especially for their children. Conclusions: Exposure to pesticides was shown to be one of the most important causes of acute leukemia. It seems that there is a need to educate the people on public health importance of exposure to pesticides especially during school time to reduce the risk of malignancies during childhood.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.3
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• pp.941-944
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• 2012

Objective: The aim of current study was to evaluate the changes of health-related quality of life (HRQoL) and its clinical, demographic and socioeconomic determinants during chemotherapy and 4 months follow-up in women with breast cancer using a repeated measures framework. Methods and Materials: A double blind cohort study was performed in 100 breast cancer patients given fluorouracil, doxorubicin and cyclophosphamide (FAC) or docetaxel, doxorubicin, cyclophosphamide (TAC) in south of Iran. HRQoL was assessed at baseline, end of chemotherapy and four months thereafter using the QLQ-C30 questionnaire from European Organization for Research and Treatment of Cancer (EORTC). Generalized estimating equations (GEE) was applied for statistical analysis. Results: The mean of age at baseline was $48.5{\pm}10.6$. 70% and 14% of patients were married and smokers, respectively, and 20% suffered from another disease besides breast cancer. The results of GEE showed that after control for baseline scores, the HRQoL significantly improved over time. Although, the patients in FAC group had higher scores than the TAC group, the differences also diminished over time. Smoking, marital status and having child affected some scales of HRQoL. None of other variables were significantly related to HRQoL. Conclusion: Although patients in TAC groups had lower level of HRQoL over 8 months follow up, they experienced faster improvement than the FAC group. This implies that in long-term, improvements in TAC group are higher than FAC. Having children was positively correlated with HRQoL. Generally, there were no demographic and socio-economic differences in HRQoL in these patients between the chemotherapeutic regimens.

• Korean Journal of Human Ecology
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• v.18 no.2
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• pp.501-507
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• 2009

Atopic dermatitis is one of the most common skin disease in children and a characteristic chronically recurrent form of dermatitis with a hereditary tendency, affecting infants and may extend to the childhood or th the adult age. Environmental factors, stress, and foodstuffs such as milk, egg may cause atopic dermatitis. Nc/Nga mice were used as an animal model for human atopic dermatitis. The divided by 4group such as normal group, BMAC group, FK506 group, MR group for this study raised in conventional conditions. To investigate effect of Chamomile German on atopic dermatitis in NC/Nga mice, the serum IgE and IgG1 level were measured while the severity degree of the skin lesion was examined by the naked eyes of two volunteers who were unaware of the treatment status. The results were the followings. 1. The score on the severity degree of skin dermatitis in FK 506 and MR group was lower than that in control group. 2. The serum IgE level in control group was higher 25% than that in normal group. 3. The serum level of IgE in FK506 and MR group compares to control group was decreased. 4. The serum IgG1 level was decreased more than 3.5 times in FK506 compared to control group while MR group had significantly less the serum IgG1 than control group. From the above results, treatment of Chamomile German oil had the effect on atopic dermatitis in NC/Nga mice. If scientific researches on aroma oil are performed in various way, aroma oil will be used to cure skin dermatitis as a alternative therapy in the future.

• Korean Journal of Community Nutrition
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• v.3 no.1
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• pp.12-20
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• 1998

In this study, the food intake, feces and urine of 14 primary school age boys and girls were collected and intake and excretion of iron and zinc were measured. The boys and girls were 8-12 years old and measurement continued for four weeks during which they maintained their normal living pattern. Each boy's and girl's daily intake and excretion of iron and zinc were measured and apparent digestibility and balance were also calculated. The results are as follows. Mean daily intake of iron was $14.9\pm{0.6mg}$ for the boys and $12.4\pm{0.5mg}$ for the girls. Mean daily intake of zinc was $11.8\pm{1.2mg}$ for the boys and $11.5\pm{0.4mg}$ for the girls. Mean daily fecal loss and apparent digestibility of iron was $6.1\pm{0.3mg}$ and $58.8\pm{2.0%}$ for the boys and $6.8\pm{0.1mg}$ and $44.1\pm{2.0%}$ for the girls. Mean daily fecal loss and apparent digestibility of zinc was $9.3\pm{0.2mg}$ and $14.4\pm{5.1%}$ for the boys and $9.7\pm{0.4mg}$ and $14.3\pm{4.3%}$ for the girls. Mean daily urinary loss of iron was $1.1\pm{0.1mg}$ and showed the positive balance of $7.86\pm{0.6mg}$ for the boys and $0.5\pm{0.1mg}$ and showed the positive balance of $5.14\pm{0.4mg}$ for the girls. Mean daily urinary loss of zinc was $0.5\pm{0.1mg}$ and showed the positive balance of $1.03\pm{0.6mg}$ for the girls.

• Journal of Digital Convergence
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• v.15 no.5
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• pp.495-503
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• 2017

The purpose of this study was to investigate the effect of psychobiographical intensive interview(PII) on the parent's insight, parent-child relationship characteristics and counseling session. For this, the PII was conducted to 10 mothers with school age children. PII was semi-structured form that included the intensive interview for exploring psychobiographical information and interpretation counseling of it. The results showed that the level of insight into parent's child problem and relation to parent's own problem was significantly increased. On the other hand, parent-child relationship characteristics (parental efficacy, parenting attitude, and parenting stress) were found to be significant only in some of the parenting stresses. We investigated the possibility as a counseling tool for PII through counseling session impact assessments. As a result of that, we confirmed that there were positive results in task impacts, relationship impacts, and helpful impacts.

• Journal of the Korean Society of Clothing and Textiles
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• v.33 no.2
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• pp.230-243
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• 2009

The purpose of this study was to analyse the body sizes of $7{\sim}12$ years elementary school girls and also to categorize KS size dimensions by the detailed information of ages and body shapes. For the study, the data of SizeKorea(2004) was analysed. Height, bust, waist, hip, the ratio of waist to height and hip to height were significant between age groups, but the ratio of bust to height was not. Therefore, the increase of bust size was resulted in growth of bust circumference, instead of bust volume. In the same height group, over 11 year girls had smaller waist, while over 12 year girls had bigger hip. For Grouping girls by ages and body shapes, the ages were divided into 2 groups, under 10 years old and 11 to 12 years old. The body shapes classified into 3 groups 'Stout-shape', 'Middle-shape', and 'slim-shape', by the ratios of bust to height and hip to height. 'Stout-shape' was significantly big at the almost sizes, but 'Middle-shape' was significantly big at only circumferences, not lengths. In addition, drop(the difference between bust and hip) and lower-drop(the difference between waist and hip) were in inverse proportion to the ratios of bust to height and hip to height. It meant the increases of bust-ratio and hip-ratio of 'Stout-shape' were resulted in overweight, rather than female matureness. The distribution of sizes over 0.5% were grouped for grading system and the subtotal percentiles of each group were calculated for industrial data. The groups which covered more than 10% of consumers were 2 to 6 and the 1 or 2 groups for 'Stout-shape' were also observed, so that children's ready-to wear companies could use them efficiently for their own consumer target.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• v.23 no.3
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• pp.189-230
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• 2020

The metabolic syndrome, by definition, is not a disease but is a clustering of individual metabolic risk factors including abdominal obesity, hyperglycemia, hypertriglyceridemia, hypertension, and low high-density lipoprotein cholesterol levels. These risk factors could dramatically increase the prevalence of type 2 diabetes and cardiovascular disease. The reported prevalence of the metabolic syndrome varies, greatly depending on the definition used, gender, age, socioeconomic status, and the ethnic background of study cohorts. Clinical and epidemiological studies have clearly demonstrated that the metabolic syndrome starts with central obesity. Because the prevalence of obesity has doubly increased worldwide over the past 30 years, the prevalence of the metabolic syndrome has markedly boosted in parallel. Therefore, obesity has been recognized as the leading cause for the metabolic syndrome since it is strongly associated with all metabolic risk factors. High prevalence of the metabolic syndrome is not unique to the USA and Europe and it is also increasing in most Asian countries. Insulin resistance has elucidated most, if not all, of the pathophysiology of the metabolic syndrome because it contributes to hyperglycemia. Furthermore, a major contributor to the development of insulin resistance is an overabundance of circulating fatty acids. Plasma fatty acids are derived mainly from the triglycerides stored in adipose tissues, which are released through the action of the cyclic AMP-dependent enzyme, hormone sensitive lipase. This review summarizes the latest concepts in the definition, pathogenesis, pathophysiology, and diagnosis of the metabolic syndrome, as well as its preventive measures and therapeutic strategies in children and adolescents.

• Pediatric Infection and Vaccine
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• v.8 no.1
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• pp.107-113
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• 2001

Spinal epidural abscess(SEA) is a rare condition in children. Classic symptoms are spinal ache, root pain, weakness and paralysis. The earliest symptoms of SEA in the pediatric age group are nonspecific and variable. Early diagnosis may be almost impossible when local spinal pain is inconspicuous or absent, when toxic epiphenomena divert attention from subtle signs of neurologic dysfunction and when the patient is an acutely distressed and uncooperative child. Failure to diagnosis and treat condition on a timely basis may lead to permanent neurolgic dysfunction or even death. This infection, usually located in the dorsal epidural space of the mid thoracic or lower lumbar regions, is the result of hematogenous dissemination of bacteria, usually Staphylococci, from foci of infection in the skin, or respiratory or urinary tracts. MRI was the diagnostic method of choice. A combination of antibiotics and surgical drainage remains the treatment of choice. Prognosis is excellent if surgery is performed before the development of neurologic deficit. We report a case of SEA in a child whose first presenting symptom was abdominal pain rather than spinal pain. A case is diagnosed by MRI and successfully treated with laminectomy and drainage and antibiotics.

• Hwankyungkyoyuk
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• v.13 no.2
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• pp.63-73
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• 2000

The purpose of this study are two-fold; 1) to identify the differences in the view of environmental value between 6-years-olds and 12-years-old, 2) to identify the differences in the attitude towards animals and plants between male-and female students. To accomplish the purposes of this study, two researchers deeply interviewed ten 6-years-old and 12-years-old boys and girls, respectively. First, the interviewees are asked to rank six constituents in nature, human-being, tiger, ant, gingko tree, weed, and stone, from their views of environmental value. Then, the interviewees were asked to talk about their various interaction with animals and plants. The results of this study are as follows; 1) In evaluating the value of nature constituents, 12-years-olds tended to be affected by scientific knowledge. On the other hand, 6-years-olds tended to evaluate the value of nature constituents by their emotional feeling; 2) From the perspectives of environmental ethics, 12-years-olds showed attitudes in anthropocentric or holistic ethics. On the other hand, 6-years-olds showed attitudes in nonanthropocentric ethics; 3) In evaluating the value of nature constituents, 12-year-olds tended to consider the constituent′s instrumental values and 6-years-olds tended to consider their intrinsic values; 4) From the perspectives of "ethics of care", females, especially 12-years females tended to take care of plants. The results propose more emphasis of environmental "sensuous" in school environmental education. And male- and female students should be expected fairly in their environmental attitudes, especially in taking care of natural creatures.

• Journal of the East Asian Society of Dietary Life
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• v.25 no.4
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• pp.691-702
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• 2015

This study examined the levels of risk perception of food risk elements by adopting a psychometric paradigm and analyzed factors affecting concerns about food risk elements to obtain basic materials for food safety policy. The data were collected from 296 housewives in Daegu, Korea, by a self-administered questionnaire. Frequency distributions, Pearson's correlation coefficient analysis, factor analysis, Cronbach's ${alpha}$, and multiple regression analyses were conducted by SPSS 21.0. The mean level of concern for food safety was 3.75/5.00 points, and the mean percentage of correct answers about heavy metal contamination was highest among food risk elements. The respondents perceived radioactive contaminated foods, GM foods, and endocrine disruptors as a new, delayed, scientifically unknown, involuntary, serious, and uncontrollable risk in risk perception. According to the result of factor analysis for risk perception, two factors such as non-controllability and dread were categorized. In the risk perception map, radioactive contaminated foods and GM foods were considered as an uncontrollable and dreaded risk, heavy metal contamination, endocrine disruptors, and pesticide residues as a controllable and dreaded risk, and foodborne illness and food additives as a controllable and less dreaded risk. On the other hand, the levels of concerns about food risk elements were higher in order of radioactive contaminated foods, GM foods, and endocrine disruptors. The results of multiple regression analysis showed that age, concern for food safety, percentage of correct answers about food risk elements, non-controllability, and dread influenced the concerns about food risk elements. These results imply that food safety policies should consider differences in consumer's risk perception of food risk elements.