• 제목/요약/키워드: School division

검색결과 12,329건 처리시간 0.036초

Usefulness of Photodynamic Therapy in the Management of Early Central Lung Cancer: A Report of Three Cases

  • Lee, Jong Hoo;Jeon, Kyeongman;Koh, Won-Jung;Suh, Gee Young;Chung, Man Pyo;Kim, Hojoong;Kwon, O Jung;Han, Joungho;Um, Sang-Won
    • Tuberculosis and Respiratory Diseases
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    • 제67권4호
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    • pp.338-344
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    • 2009
  • In photodynamic therapy, a chemical photosensitizer is activated by light of a specific wavelength., Photodynamic therapy has been combined with bronchoscopy in patients who are ineligible for surgical resection in order to treat patients with early central lung cancer. Here, we describe 3 patients with early central lung cancer who were treated effectively using photodynamic therapy. Our experience shows that this approach is a useful modality in the therapy of these types of tumors.

Late-Onset Distant Metastatic Upper Urinary Tract Urothelial Carcinoma Mimicking Lung Adenocarcinoma

  • Lim, Jun-Hyeok;Jeon, Sang Hoon;Lee, Jeong Min;Kim, Lucia;Cho, Jae Hwa;Ryu, Jeong-Seon;Kwak, Seung Min;Lee, Hong Lyeol;Nam, Hae-Seong
    • Tuberculosis and Respiratory Diseases
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    • 제75권1호
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    • pp.32-35
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    • 2013
  • Urothelial carcinomas (UCs) can occur in the upper urinary tract or lower urinary tract. Upper urinary tract urothelial carcinoma (UUT-UC) is relatively a rare disease and accounts for only about 5% of UC cases. Sporadic cases of late-onset metastasis, associated with UC of the bladder, have occasionally been reported. In contrast, no late-onset distant metastatic UUT-UC without local recurrence has, to the best of our knowledge, been reported in the English literature. We report an extremely rare case of distant metastatic UC, mimicking lung adenocarcinoma that originated from UUT-UC 12 years previously.

Evaluation of Renal Toxicity by Combination Exposure to Melamine and Cyanuric Acid in Male Sprague-Dawley Rats

  • Son, Ji Yeon;Kang, Yoon Jong;Kim, Kyeong Seok;Kim, Tae Hyung;Lim, Sung Kwang;Lim, Hyun Jung;Jeong, Tae Cheon;Choi, Dal Woong;Chung, Kyu Hyuck;Lee, Byung Mu;Kim, Hyung Sik
    • Toxicological Research
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    • 제30권2호
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    • pp.99-107
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    • 2014
  • Melamine-induced nephrotoxicity is closely associated with crystal formation in the kidney caused by combined exposure to melamine (Mel) and cyanuric acid (CA). However, there are few dosage-finding studies for toxicological evaluation of chronic co-exposure to Mel and CA. The objective of this study was to investigate the possible mechanism by which a Mel and CA mixture lead to renal toxicity in rats. Mel and CA were co-administered to rats via oral gavage for 50 days. Nephrotoxicity was determined by measuring blood urea nitrogen (BUN) and serum creatinine (sCr) levels. Relative kidney weights were significantly increased in rats after co-exposure to Mel+CA (63/6.3 or 630/6.3 mg/kg) mixtures. BUN and sCr levels were significantly increased after Mel and CA co-exposure. Taken together, significant increase in KIM-1, NGAL, and calbindin levels were observed in the urine of rats exposed to Mel+CA (63/6.3 or 630/6.3 mg/kg) compared with the corresponding control group. Histological analysis revealed epithelial degeneration and necrotic cell death in the proximal tubules of the kidney after co-exposure to Mel+CA (63/6.3 or 630/6.3 mg/kg). Our data suggest that Mel-mediated renal toxicity may be influenced by CA concentrations in Mel-contaminated milk or foods.