• Journal of Physiology & Pathology in Korean Medicine
• /
• v.24 no.3
• /
• pp.373-379
• /
• 2010

There has been a need for establishing operational curriculum for chinese characters and chinese writing used by traditional korean medicine (TKM), but it was not carefully recognized so far. We analysed the frequency of unicode chinese characters from five medical textbooks and showed prerequisite chinese characters for TKM beginners. It was found that 之, 者, 不, 也, 而, 氣, 陽, 陰, 下, 其, 病, 爲, 人, 以, 中, 則, 於, 脈, 上, 故 are the most frequently used 20 chinese characters. We also showed that adequate prerequisite chinese character should be designated for the more efficient education of TKM. This study was the first systematic approach to get essential and prerequisite chinese characters for the education of TKM. The prerequisite characters by this study will be used for the development of KEET (Korean Medicine Education Eligibility Test), entrance exam to the Colleges of Oriental Medicine and textbooks, and educational curriculum of premed students.

• Journal of Gastric Cancer
• /
• v.21 no.3
• /
• pp.246-257
• /
• 2021

Purpose: It is unclear whether high-definition (HD) imaging improves visibility and diagnostic ability in early gastric cancer (EGC) compared with standard-definition (SD) imaging. We aimed to compare the diagnostic performance and visibility scores of HD and SD ultraslim endoscopes in EGC. Materials and Methods: We used HD and SD ultraslim endoscopes to obtain 60 images with similar compositions of gastric environments. Of the 60 images, 30 showed EGC (15 images for each modality) and 30 showed no EGC (15 images for each modality). Seventeen endoscopists evaluated the presence and location of the lesions in each image. Diagnostic ability was compared between modalities. The color difference between a lesion and the surrounding mucosa (ΔE) was measured and compared between the modalities. Results: The ability of HD to detect EGC was significantly higher than that of SD (accuracy: 80.8% vs. 71.6%, P=0.017; sensitivity: 94.9% vs. 76.5%, P<0.001; positive predictive value, 76.2% vs. 55.3%, P<0.001; and negative predictive value (NPV), 94.1% vs. 73.5%, P<0.001). The ability of HD to determine the horizontal extent of EGC was significantly higher than that of SD (accuracy: 71.0% vs. 57.8%, P=0.004; sensitivity: 75.3% vs. 49.0%, P<0.001; NPV, 72.9% vs. 55.9%, P<0.001; and area under the curve: 0.891 vs. 0.631, P=0.038). The mean ΔE was significantly higher for HD than for SD (10.3 vs. 5.9, P=0.011). Conclusions: The HD ultraslim endoscope showed a higher diagnostic performance in EGC than the SD endoscope because it provided good color contrast.

• Journal of Microbiology and Biotechnology
• /
• v.33 no.9
• /
• pp.1179-1188
• /
• 2023

Escherichia coli, particularly multidrug-resistant (MDR) strains, is a serious cause of healthcare-associated infections. Development of novel antimicrobial agents or restoration of drug efficiency is required to treat MDR bacteria, and the use of natural products to solve this problem is promising. We investigated the antimicrobial activity of dried green coffee (DGC) beans, coffee pulp (CP), and arabica leaf (AL) crude extracts against 28 isolated MDR E. coli strains and restoration of ampicillin (AMP) efficiency with a combination test. DGC, CP, and AL extracts were effective against all 28 strains, with a minimum inhibitory concentration (MIC) of 12.5-50 mg/ml and minimum bactericidal concentration of 25-100 mg/ml. The CP-AMP combination was more effective than CP or AMP alone, with a fractional inhibitory concentration index value of 0.01. In the combination, the MIC of CP was 0.2 mg/ml (compared to 25 mg/ml of CP alone) and that of AMP was 0.1 mg/ml (compared to 50 mg/ml of AMP alone), or a 125-fold and 500-fold reduction, respectively, against 13-drug resistant MDR E. coli strains. Time-kill kinetics showed that the bactericidal effect of the CP-AMP combination occurred within 3 h through disruption of membrane permeability and biofilm eradication, as verified by scanning electron microscopy. This is the first report indicating that CP-AMP combination therapy could be employed to treat MDR E. coli by repurposing AMP.

• Education of Primary School Mathematics
• /
• v.27 no.2
• /
• pp.187-198
• /
• 2024

The addition and subtraction relationship and the multiplication and division relationship are explicitly dealt with in second and third grade mathematics textbooks. However, these relationships are not discussed anymore in the problem situations and activities in the 4th, 5th, and 6th grade mathematics textbooks. In this study, we investigate the calculation principles of subtraction and division in the elementary school mathematics textbooks. Based on our investigation, we justify the addition and subtraction relationship and the multiplication and division relationship at the level of children's understanding so that we discuss some problem situations and activities where the relationships can be applied to subtraction and division. In addition, we suggest educational implications that can be obtained from children's applying the relationships and the properties of equations to subtraction and division.

• Journal of Fisheries and Marine Sciences Education
• /
• v.27 no.6
• /
• pp.1556-1568
• /
• 2015

The objectives of this study were to inquiry of application types and use methodology of EBS-CSAT prep books of vocation education division in specialized vocational high schools. Research participants are 8 specialized vocational high school teachers in Seoul and Gyeonggi, and subjects are basic industry and basic drawing. The teachers had using EBS-CSAT prep books in class or after-school. The results are as follows: The teachers used items explanation of after-school rather than regular classes using EBS-CSAT prep books of vocation education division in specialized vocational high schools. Online lectures were used for self-directed learning of specialized vocational high school students rather than regular classes. Students and teachers of specialized vocational high school needed EBS-CSAT prep books of vocation education division by free gift instead of EBS-CSAT prep books of Korea language, english, math.

• Proceedings of the Korean Society of Life Science Conference
• /
• 2007.10a
• /
• pp.113.1-113.1
• /
• 2007

See Full Text

• Proceedings of the Korean Society of Life Science Conference
• /
• 2007.10a
• /
• pp.113.2-113.2
• /
• 2007

See Full Text

• Proceedings of the Korean Society of Life Science Conference
• /
• 2007.10a
• /
• pp.114.1-114.1
• /
• 2007

See Full Text

• Proceedings of the Korean Society of Life Science Conference
• /
• 2007.10a
• /
• pp.114.2-114.2
• /
• 2007

See Full Text

• Journal of Physiology & Pathology in Korean Medicine
• /
• v.24 no.5
• /
• pp.837-842
• /
• 2010

The purpose of this study is to develop bathing aids as a strategic products to promote the medical tourism in Sancheong Jirisan Oriental medicinal herbs special district using medicinal herbs produced in Sancheong province, and to verify the effect of the bathing aids in vitro. We investigated the cytotoxicity activity, antioxidant activity, antiaging and whitening effects of Sanchung-PNU 1 (SP1) and Sanchung-PNU 2 (SP2) made with traditional medicinal herbs. The cytotoxicity activity was measured by MTT (3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazolium bromide) assay. Antioxidant activities were determined by DPPH (1.1-diphenyl-2-picrylhydrazyl) radical scavenging capacity assay. We measured the inhibitory effect against tyrosinase activity to prove the whitening effect, and the inhibitory effect against elastase activity to prove the anti-aging effect. Two proposed prescriptions, SP1 and SP2, showed not significant cytotoxicity but significant (p<0.001) improvement in anti-oxidation, anti-wrinkle, and whitening effects compared to the control group. The result shows that these bathing aids have excellent DPPH radical scavenging effect and significant inhibitory effect against elastase and tyrosinase activity. These findings suggest that these bathing aids have a strong antioxidant, anti-aging, and whitening effect.