• Journal of Korean Academy of Nursing
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• v.17 no.3
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• pp.177-183
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• 1987

This study investigated and evaluated a method effectively promote a communication function in families with a schizophrenic patient and the patients' interaction, by a family approach using reinforcement of functional communication between patients and their parents. The subjects of the study were patients receiving treatment in Won Gwang University Mental Hospital from July 1985 to July 1986, and their families. In the experimental group, a family approach using reinforcement of functional communication twice a week was taught. Each of the six sessions took sixty minutes, during which the interviews and questionaires were carried out. The total number of patients receiving treatment in the hospital at that time, 42, were divided by a systematic method into 20families in an experimental group and 22 in a control group. The results from testing the hypotheses established in this study, to analyse the effects of family approach through reinforcement of functional communication, are as follows; The results of the test of the first hypothesis are shown in Table 1. “patients and their parents in an experimental group receiving group training in reinforcement of functional communication will show a greater degree of interaction than those of the control group” was supported. Significant differences included Main Effects p＜.001, Interactions p＜.001 and Explained p＜.001 in the interactions of patients, and mothers. Scores were higher for the experimental group after the treatment as well as higher than the control group.

• Journal of Korean Academy of Nursing
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• v.29 no.6
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• pp.1314-1323
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• 1999

The purpose of the study was to determine the effects of the 8-week, 15-session group art therapy program on self-esteem and mental health status in chronic schizophrenic inpatients. The sample consisted of two groups of chronic schizophrenic inpatients: 10 patients with an average of total disease duration of 8.90 years who participated in a 8-week group art therapy program, and 8 comparison subjects with an average of total disease duration of 8.25 years who did not participate in the program. A pretest-posttest quasiexperimental design was used to assess self-esteem and mental health status at the beginning and at the end of the 8-week, 15-session group art therapy program. The time points for obtaining data were matched for both groups. The effectiveness of the 8-week group art therapy program was assessed by Rosenberg's Self-esteem Scale(Rosenberg, 1965) and SCL-90- R(Derogatis et al., 1973). SPSSWIN 8.0 was utilized for data entry and analysis employing Mann-Whitney U test. The findings of the study indicated the followings : (a) No significant differences were found between two groups in self-esteem and (b) The experimental group showed significantly lower scores in obsessive-compulsive symptom dimension and interpersonal sensitivity symptom dimension on the SCL-90-R than the comparison group after participating in the group art therapy program. In conclusion, the findings showed the possibility of applying group art therapy as an effective nursing intervention for patients with lack of verbal communication skills and social interaction to improve their interpersonal relationship.

• Korean Journal of Psychosomatic Medicine
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• v.4 no.2
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• pp.226-244
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• 1996

This study was designed to evaluate the social support network of schizophrenic patients. 64 schizophrenic patients being treated as out-door patient were compared with 30 neurotic control patients. Schizophrenics were divided into positive, subpositive, subnegative and negative subgroups by present symptom and social network of both schizophrenics and control group were evaluated. The results are as follows: 1) Social network of schizophrenics was smaller than that of control group. Size of social network of schizophrenics was 10.6 and that of control group was 23.5. 2) In both kin and nonkin, social network of schizophrenics was smaller than that of control group. Of the kin, schizophrenics were more supported by wife or husband, father, and mother, but were less supported by brother, son and other relatives. 3) There was no difference in the kin or nonkin or total supporters between the four subgroups of schizophrenics. But, subgroup of schizophrenics which was divided as having negative symptom had smaller network than control group in active formal and informal supporters. 4) When divided into 4 support areas, schizophrenics was remarkably less supported in emotional, instrumental and appraisal support area than control group, but there was no difference in the informational support areas. 5) Compared with control group, schizophrenics more often mentioned parent and ten often mentioned nonkin supporter as the one that is most important to him. 6) Schizophrenics had smaller cluster and less leisure activity than control group. Subgroup of schizophrenics who was divided as having negative symptom had less frequency of leisure activity than other subgroups.

• Korean Journal of Biological Psychiatry
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• v.24 no.1
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• pp.32-38
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• 2017

Objectives This study was aimed to investigate the association between amisulpride-induced hyperprolactinemia and the Taq1A polymorphism in the D2 dopamine receptor gene (DRD2) in schizophrenic patients. Methods The plasma concentrations of prolactin were measured before and after treatment with amisulpride in one hundred and twenty-five schizophrenic patients. The effect of the Taq1A variants of the DRD2 on the risk of amisulpride-induced hyperprolactinemia was the main the outcome measure. The genotyping for Taq1A (rs1800497) polymorphism was performed using TaqMan single nucleotide polymorphism (SNP) genotyping assay. Results There was a significant difference between the prolactin level at baseline and the 6th week after treatment with amisulpride in all the subjects. However, there were no significant correlations between ΔProlactin (the difference between prolactin level at baseline and the 6th week after treatment) and the Taq1A genotypes. Conclusions This is the first study to investigate the-correlations between the Taq1A polymorphism and the amisulpride-induced hyperprolactinemia in Korean schizophrenic patients. The current results suggested the further large-scale researches on various SNPs in the DRD2 gene will establish clear goals and provide answers to the unanswered questions described in this study.

• Journal of agricultural medicine and community health
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• v.24 no.2
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• pp.351-368
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• 1999

The objective and subjective burden was evaluated toward 115 main caregivers in the family with schizophrenic patient by interview with structured questionnaire and self-report using Family Burden Scale (FBS) of family with schizophrenic patient in Korea. The results were as follows : 1) The mean age of onset by schizophrenic patient were 23 years old in male and 26 in female. 2) The mean scales of objective and subjective burden were 1.5 and 1.6. 3) By Logistic regression objective burden was significantly affected by family support (P<0.001), religion (P<0.05), occupation (P<0.05). 4) Subjective burden was significantly affected by family support (P<0.01) and family total income (P<0.05). 5) Total objective and subjective burden was significantly affected by family support (P<0.001), religion (P<0.05). In conclusion, this study suggests that main caregivers need family support from other family members. For them religion and social support are also helpful to cope with the burden to take care of the schizophrenic patients.

• Korean Journal of Social Welfare
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• v.56 no.2
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• pp.261-283
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• 2004

This study verified the effectiveness of brief family education programs for schizophrenic outpatients and their families in a community social welfare center, using a pre - post test control group design. The results of this study verified that the program was effective to improve knowledge about schizophrenia, reduce feelings of rejection and anxiety about patients, and help the patients to recognize their family emotional support. Therefore, it was found in this study that the brief family education program in the community social welfare center had a positive impact on schizophrenic outpatients and their families' treatment and rehabilitation. From the results of this study, it can be seen that this program positively effects the treatment and rehabilitation of schizophrenic patients and the stability of their families. The program can also be easily utilized as a community resource. Furthermore, the results of this study can be utilized as fundamental support to suggest the need for mental health programs in community social welfare centers. This study suggested the importance of increasing the number of mental health professionals working in this arena. There is also a need to create additional supportive programs for schizophrenic outpatients and their families. Follow up care also needs to be provided to families after completing family education programs. Continuous study is needed in these areas.

• Journal of Korean Academy of Nursing
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• v.44 no.3
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• pp.339-349
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• 2014

Purpose: This study was done to develop a measurement for stress experienced by patients with schizophrenia during hospitalization. Methods: The preliminary tool was developed through in-depth interviews and a validity verification test of content. For data collection, 15 inpatients with schizophrenia were selected as participants for in-depth interviews and 195 patients admitted to one of eight psychiatric hospitals in four provinces were recruited as participants to test reliability and validity of the preliminary tool. Results: The questionnaire was developed as a four-point Likert-type scale in a self-report form with 28 items. Factor analysis showed 28 items in six factors. Factors were named 'Unjust human rights infringement', 'Futureless life', 'Alienation from other family members', 'Infringement of basic needs', 'Infringement of personal preference' and 'Inconvenience of shared living'. The six factors explained 63.5% of the total variance. Cronbach's alpha for the total items was .93 and for the factors ranged from .65 to .87. Conclusion: A tool to measure stress in patients hospitalized with schizophrenic was developed based on identified hospitalization stress experiences. Study results indicate that this tool can be used to evaluate hospitalization stress in these patients and will contribute to establishing nursing interventions for relief of hospitalization stress.

• Journal of Korean society of Dental Hygiene
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• v.14 no.3
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• pp.353-362
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• 2014

Objectives : The purpose of the study is to investigate the xerostomia in the chronic severe psychiatric patients in Korea because there were few reports on xerostomia in the psychiatric patients. Methods : The subjects were 61 psychiatric patients in the mental hospital by convenience cluster sampling. A self-reported symptom questionnaire was filled out by the three researchers on the basis of medical records by the informed consent. The stimulated salivary flow rate of the patients was measured by saliva sampling. Results : The subjects consisted of 45.9% of male and 54.1% of female. High school graduation accounted for 40.0% and 20.0% did not attend the school. The majority of the patients were medicaid recipients. Schizophrenia accounted for 86.9% and most patients were long term care recipients. A total of 68.9% of the patients suffered from salivary dysfunction. The medication in schizophrenia seemed to decrease the stimulated salivary flow rate and made the patients difficult in chewing and swallowing due to xerostomia and low saliva secretion(p<0.05). Conclusions : Medication in schizophrenic patients caused the salivary dysfunction. So the collaboration between the psychiatry doctors and dental hygienists is very important to improve the salivary secretion in the schizophrenic patients. The continuous and long term care of the xerostomia will help the patients maintain the good oral hygiene.

• Korean Journal of Biological Psychiatry
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• v.14 no.3
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• pp.184-193
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• 2007

Objectives:There is increasing evidence that the cerebellum plays an important role in cognition and psychiatric symptoms as well as motor coordination. The concept of cognitive dysmetria has been making cerebellar function in schizophrenia the focus of current studies. In other words, disruption in the corticocerebellum-thalamic -cortical circuit could lead to disordered cognition and clinical symptoms of schizophrenia. The purposes of this study were to determine cerebellar dysfunction in male schizophrenic patients semiquantitatively with ICARS and to investigate the clinical and cognitive correlates of ICARS in patients. Methods:We compared the scores of cerebellar neurologic sign using ICARS in 47 male patients with a DSM-IV-TR diagnosis of schizophrenia with 30 gender and age-matched healthy control subjects. The semiquantitative 100-point ICARS consists of 19 items divided into 4 unequally weighted subscores:posture and gait disturbances, kinetic functions, speech disorders and oculomotor disorders. All subjects were also assessed with cognitive function test. Cognitive functions were evaluated by Korean-Mini Mental Status Examination (K-MMSE), Verbal fluency test, and Clock drawing test. The patients were administered Korea version of Positive and Negative Symptom Scale(K-PANSS) to assess the symptom severity. Results:Schizophrenic patients had significantly higher scores on the ICARS than control subjects with posture and gait disturbances, kinetic functions, and oculomotor disorders. They also showed more significant impairments in cognitive function tests than control subjects. There was a significant correlation between ICARS and negative symptoms of patients. In cognitive function test, Clock drawing test was significantly associated with negative symptoms. In addition, Clock drawing test was negatively correlated with the total score of ICARS. Conclusion:In this study, we confirmed that schizophrenic patients have significant impairments in cognitive and cerebellar function, and that those were related with negative symptoms of schizophrenic patients. These results support a role of the cerebellum in schizophrenia. It is meaningful that we used a structured, and reliable procedure for rating neurological soft signs, ICARS. We hope that future prospective studies using a similar design help that rate of neurological sign should have been visible with the progression of illness.

• Korean Journal of Biological Psychiatry
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• v.4 no.1
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• pp.127-131
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• 1997

Objective : To evaluate the clinical efficacy of adjuvant sertraline treatment in chronic schizophrenic patients, we carried out a double-blind, placebo controlled study. Method : Thirty six inpatients who fulfilled DSM-III-R criteria for chronic schizophrenia were randomly assigned to sertraline and placebo groups in a double-blinded fashion. A history of at least 2 years of illness and at least six months of hospitalization were prerequisities for inclusion in the study. Patients were received sertraline 50mg or placebo for 8 weeks in addition to their routine haloperidol regimen. Positive and Negative Syndrome Scale (PANSS), Clinical Global Impression(CGI), Simpson-Angus Scale(S-A) were evaluated at 5 points ; baseline, 2, 4, 6, and 8 weeks of treatment. Results : The groups were controlled for age, gender, and length of illness. There were no significant differences in three PANSS factros(positive, negative, general), CGI, and S-A scale scores at any between sertaline and placebo treatment. Conclusion : This placebo controlled study showed no significant effects of sertraline on negative and positive symptoms in chronic schizophrenic patients.