• Title/Summary/Keyword: Sap

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Preparation and Evaluation of $PGE_1$ Transurethral Suppositories (프로스타글란딘 $E_1$ 요도좌제의 제조 및 평가)

  • Kim, Jong-Oh;Quan, Qi-Zhe;Rhee, Jong-Dal;Choi, Han-Gon;Yong, Chul-Soon
    • Journal of Pharmaceutical Investigation
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    • v.30 no.3
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    • pp.173-178
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    • 2000
  • The purpose of this work is to develop a transurethral suppository containing prostaglandin $E_1\;(PGE_1)$, which stabilizes the drug, gives no irritation to physiological body and enhances the erectile response of $PGE_1.\;PGE_1$ transurethral suppositories were prepared with various amounts of compositions such as saturated polyglycolysed glyceride $(Suppocire^{\circledR}\;AP,\;SAP)$, polyoxyethylene hydrogenated castor oil (HCO-50) and ethanol. The melting points, viscosities and $PGE_1$ release of the suppositories were investigated. Ocular irritation test was carried out after application of $PGE_1$ suppository to rabbit's eye. The intracavernous pressure (ICP), penile length and duration of erectile response were determined after transurethral administration of $PGE_1$ suppository and compared with those after intracavernosal injection of $PGE_1$ solution to cats. HCO-50 hardly affected the melting points and viscosities of $PGE_1$ suppositories. Additionally, $PGE_1$ transurethral suppositories, whose melting point ranges was $34-35^{\circ}C$, was speedily melted in physiological body. HCO-50 significantly decreased the dissolution rates of $PGE_1$ from the suppositories. Dissolution mechanism analysis showed the release of $PGE_1$ was proportional to the square root of time, indicating that $PGE_1$ might be released from the suppositories by Fickian diffusion. The release rate of $PGE_1$ from $PGE_1$ suppository [PGE1/SAP/HCO-50/ethanol (1/94.5/2.5/2%)] was about 80% within 2 h. This $PGE_1$ suppository gave no significant irritation to the ocular tissue, expecting that it gave no irritation to the urethral tissue less sensive than ocular tissue. Furthermore, $PGE_1$ in this suppository was stable at $4^{\circ}C$ for 2 years. This suppository increased the ICP and penile erection similar to those of injectable $PGE_1$ solution. However, it gave 2.5-fold increased duration of erectile response than injectable $PGE_1$ solution. Our results suggested that it gave more effective erectile response than injectable $PGE_1$ solution in cats. It is concluded that this $PGE_1$ suppository with good safety, excellent stability and enhanced erectile response, could be a more effective and convenient transurethal delivery system of $PGE_1$.

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Stability Analysis of Multi-Functional Fishway with Underground Passage (지하이동통로가 구비된 다기능 어도의 안정성 검토)

  • Lee, Young-Jae
    • Journal of the Korea institute for structural maintenance and inspection
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    • v.18 no.6
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    • pp.50-59
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    • 2014
  • In this paper, Reinforced concrete (R/C) and R/C+steel plate concrete slab was carried out by SAP2000 software program in order to compare the stability of the multi-functional fishway, that is Bonggok fishway, built at Bonggok river recently in Gumi city, when the size of underground passage is $1m{\times}0.2m$, $1m{\times}0.4m$, $1m{\times}0.6m$ and the velocity is 0.8m/s, 1.2m/s, 1.6m/s respectively for the S2 (R/C+S/C). The analysis shows the maximum stress of S2 decreases less 26~50% than that of Bonggok, bending moment of sidewall decreases less 28~54%, maximum stress of side wall decreases less 17~31%, bending moment of upper slab decreases less 24~47%, maximum stress of upper slab decreases less 4~20%, and bending moment decreases less 10~27% than that of Bonggok. The complementation is required as much as the following percent; 27% and 25% for the maximum stress and bending moment of underground passage, 15% and 24% for the side wall maximum stress and bending moment, and 10% and 14% for the upper slab maximum stress and bending moment, respectively. This result shows that the S2 is greatly superior to that of the Bonggok fishway, and underground passage size of $1m{\times}0.4m$ is superior to that of $1m{\times}0.2m$ or $1m{\times}0.6m$, and R/C+S/C slab is superior to that of R/C slab. This result is expected to be the basic data for the construction and design of the multi-functional fishway.

A Study on the Implementation of the Multi-Process Structured ISDN Terminal Adaptor for Sending the Ultra Sound Medical Images (다중처리 구조를 갖는 초음파 의료영상 전송용 ISDN(Integrated Services Digital Network) TA(Terminal Adaptor) 구현에 관한 연구)

  • 남상규;이영후
    • Journal of Biomedical Engineering Research
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    • v.15 no.3
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    • pp.317-324
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    • 1994
  • This paper proposed a new method in the implementation of ISDN (integrated services digital network) LAPD (link access procedure on the D-channel) and LAPB (link access procedure on the B-channel) protocols. The proposed method in this paper implement ISDW LAPD protocol through multi-tasking operating system and adopt a kernel part that is changed operating system to target board. The features of implemented system are (1) the para.llel processing of the events generated at each layer, as follows (2) the supporting necessary timers for the implementation of ISDW LAPD protocol from the kernel part by using software, (3) the recommanded SAP (Service Access Point) from CCITT was composed by using port function in the operating system. With the proposed method, the protocols of ISDH layerl, layer2 and layer3 (call control) were implemented by using the kernel part and related tests were carried out by connecting the ISDH terminal simulator to ISDN S-interface system using the ISDN LAPD protocol The results showed that ISDW S-interface terminals could be discriminated by TEI (Terminal Equipment Identifier) assignment in layer 2 (LAPD) and the message transmission of layer 3 was verified by establishing the multi-frame transmission and then through the path established by the LAPD protocol, a user data was tranfered and received on B-channel with LAPB protocol Thererfore, as new efficient ISDN S-interface environment was implemented in the thesis, it was verified that the implemented system can be utilized by connecting ISDW in the future to transfer a medical image data.

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Comparative analysis of fusion factors affecting the accuracy of injection amount of remote fluid monitoring system (원격 수액모니터링 시스템의 주입량의 정확도에 영향을 주는 융합인자의 비교 분석)

  • Kim, Seon-Chil
    • Journal of the Korea Convergence Society
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    • v.13 no.3
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    • pp.125-131
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    • 2022
  • Recently, the prevalence of remotely managed patient care systems in medical institutions is increasing due to COVID-19. In particular, in the case of fluid monitoring, hospitals are considering introducing it as a system that can reduce patient safety and nurses' work. There are two products under development: a load cell method that measures weight and a method that detects drops of sap by infrared sensing. Although each product has differences in operation principle, sensor type, size, usage, and price, medical institutions are highly interested in the accuracy of the data obtained.In this study, two prototypes with different sensor methods were manufactured and the total amount of infusion per hour was measured to test the accuracy, which is the core of the infusion monitoring device. In addition, when there was an external movement, the change in the measured value of the sap was tested to evaluate the accuracy according to the measurement method. As a result of the experiment, there was a difference of less than 5% in the measurement value error of the two devices, and the load cell method showed a difference in the low-capacity measurement value and the infrared method in the high-capacity measurement value. As a result of this experiment, there was little difference in accuracy according to the sensor method of the infusion monitoring device, and it is considered that there is no problem in accuracy when used in a medical institution.

Implement of Web-based Remote Monitoring System of Smart Greenhouse (스마트 온실 통합 모니터링 시스템 구축)

  • Dong Eok, Kim;Nou Bog, Park;Sun Jung, Hong;Dong Hyeon, Kang;Young Hoe, Woo;Jong Won, Lee;Yul Kyun, Ahn;Shin Hee, Han
    • Journal of Practical Agriculture & Fisheries Research
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    • v.24 no.4
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    • pp.53-61
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    • 2022
  • Growing agricultural products in greenhouses controlled by creating suitable climatic conditions and root zone of crop has been an important research and application subject. Appropriate environmental conditions in greenhouse are necessary for optimum plant growth improved crop yields. This study aimed to establish web-based remote monitoring system which monitors crops growth environment and status of crop on a real-time basis by applying to greenhouses IT technology connecting greenhouse equipment such as temperature sensors, soil sensors, crop sensors and camera. The measuring items were air temperature, relative humidity, solar radiation, CO2 concentration, EC and pH of nutrient solution, medium temperature, EC of medium, water content of medium, leaf temperature, sap flow, stem diameter, fruit diameter, etc. The developed greenhouse monitoring system was composed of the network system, the data collecting device with sensors, and cameras. Remote monitoring system was implemented in a server/client environment. Information on greenhouse environment and crops is stored in a database. Items on growth and environment is extracted from stored information, could be compared and analyzed. So, A integrated monitoring system for smart greenhouse would be use in application practice and understanding the environment and crop growth for smart greenhouse management. sap flow, stem diameter and pant-water relations

RPA Log Mining-based Process Automation Status Analysis - An Empirical Study on SMEs (RPA 로그 마이닝 기반 프로세스 자동화 현황 분석 - 중소기업대상 실증 연구)

  • Young Sik Kang;Jinwoo Jung;Seonyoung Shim
    • Journal of Intelligence and Information Systems
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    • v.29 no.1
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    • pp.265-288
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    • 2023
  • Process mining has generally analyzed the default logs of Information Systems such as SAP ERP, but as the use of automation software called RPA expands, the logs by RPA bots can be utilized. In this study, the actual status of RPA automation in the field was identified by applying RPA bots to the work of three domestic manufacturing companies (cosmetic field) and analyzing them after leaving logs. Using Uipath and Python, we implemented RPA bots and wrote logs. We used Disco, a software dedicated to process mining to analyze the bot logs. As a result of log analysis in two aspects of bot utilization and performance through process mining, improvement requirements were found. In particular, we found that there was a point of improvement in all cases in that the utilization of the bot and errors or exceptions were found in many cases of process. Our approach is very scientific and empirical in that it analyzes the automation status and performance of bots using data rather than existing qualitative methods such as surveys or interviews. Furthermore, our study will be a meaningful basic step for bot behavior optimization, and can be seen as the foundation for ultimately performing process management.

Experimental and numerical investigation on flexural response of reinforced rubberized concrete beams using waste tire rubber

  • Memduh Karalar;Hakan Ozturk;Yasin Onuralp Ozkilic
    • Steel and Composite Structures
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    • v.48 no.1
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    • pp.43-57
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    • 2023
  • The impacts of waste tire rubber (WTR) on the bending conduct of reinforced concrete beams (RCBs) are investigated in visualization of experimental tests and 3D finite element model (FEM) using both ANSYS and SAP2000. Several WTR rates are used in total 4 various full scale RCBs to observe the impact of WTR rate on the rupture and bending conduct of RCBs. For this purpose, the volumetric ratios (Vf) of WTR were chosen to change to 0%, 2.5%, 5% and 7.5% in the whole concrete. In relation to experimental test consequences, bending and rupture behaviors of the RCBs are observed. The best performance among the beams was observed in the beams with 2.5% WTR. Furthermore, as stated by test consequences, it is noticed that while WTR rate in the RCBs is improved, max. bending in the RCBs rises. For test consequences, it is clearly recognized as WTR rate in the RCB mixture is improved from 0% to 2.5%, deformation value in the RCB remarkably rises from 3.89 cm to 7.69 cm. This consequence is markedly recognized that WTR rates have a favorable result on deformation values in the RCBs. Furthermore, experimental tests are compared to 3D FEM consequences via using ANSYS software. In the ANSYS, special element types are formed and nonlinear multilinear misses plasticity material model and bilinear misses plasticity material model are chosen for concrete and compression and tension elements. As a consequence, it is noticed that each WTR rates in the RCBs mixture have dissimilar bending and rupture impacts on the RCBs. Then, to observe the impacts of WTR rate on the constructions under near-fault ground motions, a reinforced-concrete building was modelled via using SAP2000 software using 3-D model of the construction to complete nonlinear static analysis. Beam, column, steel haunch elements are modeled as nonlinear frame elements. Consequently, the seismic impacts of WTR rate on the lateral motions of each floor are obviously investigated particularly. Considering reduction in weight of structure and capacity of the members with using waste tire rubber, 2.5% of WTR resulted in the best performance while the construction is subjected to near fault earthquakes. Moreover, it is noticeably recognized that WTR rate has opposing influences on the seismic displacement behavior of the RC constructions.

Development of Expert System for Tower Cranes

  • Kim, Ki-sung;Kang, Dong-gil;Hong, Ki-sup
    • Journal of Ship and Ocean Technology
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    • v.3 no.2
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    • pp.27-48
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    • 1999
  • The paper is concerned with application to develop the expert system, which structural analysis and design process for tower cranes. The system is organized into three groups. One is pre-processor for creating input data files, another is `model former' which combines knowledge-base with inference engine for automatic generating structural analysis models, a third is application group for final analysis checks. In this study, geometric subroutine of `model former' designates node positions, nodes, elements numbers and element types. Load data subroutine computes weight of tower crane and device, slewing force, cargo load, wind force form rules or equations in knowledge-base. Also, Property and boundary subroutine applies element properties and boundary conditions to suitable elements and nodes. Design and analysis expert system for tower crane integrates these subroutine, `model former' and pre-processor. RBR(Rule-Base Reasoning) was adopted for a reasoning strategy of this expert system. And this expert system can produce structural analysis model and data, which can be used in ordinary structural analysis program (SAP, ADINA or NASTRAN, etc.). In this paper, this expert system produces format of the analysis model data, which are used in MSC/NASTRAN. The main discussions included in the paper are introduction of the tower crane and structural analysis, composition of the design expert system for tower crane and structural analysis using the expert system.

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A curved shell finite element for the geometrically non-linear analysis of box-girder beams curved in plan

  • Calik-Karakose, Ulku H.;Orakdogen, Engin;Saygun, Ahmet I.;Askes, Harm
    • Structural Engineering and Mechanics
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    • v.52 no.2
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    • pp.221-238
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    • 2014
  • A four-noded curved shell finite element for the geometrically non-linear analysis of beams curved in plan is introduced. The structure is conceived as a sequence of macro-elements (ME) having the form of transversal segments of identical topology where each slice is formed using a number of the curved shell elements which have 7 degrees of freedom (DOF) per node. A curved box-girder beam example is modelled using various meshes and linear analysis results are compared to the solutions of a well-known computer program SAP2000. Linear and non-linear analyses of the beam under increasing uniformly distributed loads are also carried out. In addition to box-girder beams, the proposed element can also be used in modelling open-section beams with curved or straight axes and circular plates under radial compression. Buckling loads of a circular plate example are obtained for coarse and successively refined meshes and results are compared with each other. The advantage of this element is that curved systems can be realistically modelled and satisfactory results can be obtained even by using coarse meshes.

Effects of the Natural Materials on Growth and Quality of Radish (天然物質 處理가 무의 生長과 品質에 미치는 영향)

  • Kim, Kyung-Je
    • Korean Journal of Organic Agriculture
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    • v.10 no.3
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    • pp.79-86
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    • 2002
  • This study was carried out to investigate the effects of natural materials on quality and yield of radish. The GB$_{10}$, Chitofarm, chaff charcoal, and chaff charcoal sap were used as natural materials. The total plant weight, root weight, root length, and root width of radish in treatment with natural materials showed significant differnce compared with control. The yield of radish in 1% of GB$_{10}$ treatment was increased 75% compared with control. The chemical components were increased in total plant of radish treated with natural materials compared with control. This appears that natural materials increase the quality of radish.

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