• 대한한의진단학회지
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• 제18권1호
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• pp.45-50
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• 2014

Objectives This study was designed to report the effect of Samultang-gamibang(四物湯加味方) for insomnia caused by blood deficiency (syndrome) after excessive weight control treatment with herbal medication Methods This is a retrospective case report. We reviewed the patient's medical record after taking the patient's informed consent. Results After treatment, a patient feels calm and satisfaction emotionally as sleeping time has increased from 2hours to 6hours, the fatigue after sleeping has been reduced, and the quality of sleep has become better. Conclusions This case report suggests that Samultang-gamibang can be effective in improving sleep duration and quality if the patient suffers insomnia due to hyul-heo syndrome. Also the woman who have symptom of hyul-heo(血虛) after weight control through decreased food consumption, should bo-hyul(補血).

• 동의생리병리학회지
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• 제19권3호
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• pp.696-704
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• 2005

This experiment examined the effect of Samultang-gamibang (SGB) on hair growth in spontaneous alopecia areata C57BL/6N mice. We first investigated hair growth effect of SGB compare to control groups after apply to oral administration for 10 weeks and regional treatment in skin for last 4 weeks. We second investigated the number of hair follicle and mast cells after treatment of SGB in spontaneous alopecia areata C57BL/6N mice for 10 weeks. We third investigated immunoreactive density of neuropeptides in skin of spontaneous alopecia areata C57BL/6N mice by immunohistochemical methods. The results were as follows : Hair growing effect of experimental group was observed from 7 weeks after administration of SGB (87.5%). In experimental group, the number of mast cells and eosinophils was significantly decreased compare to control group. Immunoreactive density of substance P and corticotropin releasing factor (CRF) in skin of experimental group was weakly stained in epidermis and subcutaneous tissue compare to control group. Immunoreactive density of CRF-receptor (CRF-R), CRF-binding protein (CRF-BP) in skin of experimental group was increased in epidermis, sebaceous gland, inner root sheath, outer root sheath and secondary hair germ epithelium compare to control group. These results suggest that SGB may be used in treatment of alopecia areata.