• Journal of Cerebrovascular and Endovascular Neurosurgery
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• 제25권1호
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• pp.36-49
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• 2023

Objective: Arteriovenous malformations (AVMs) are benign congenital lesions. The estimated prevalence is 10-18 per 100,000 individuals, with an incidence rate of 1.1-1.4 per 100,000 person-year; only 12% of AVMs present symptoms during life. It is important to study different characteristics associated with AVMs because these patients require multidisciplinary treatment. Methods: A descriptive, observational, longitudinal, and retrospective study was carried out from January 15, 2016 to October 19, 2021. Convenience sampling was used on patients diagnosed with arteriovenous malformation. Sociodemographic data was obtained, such as: sex, age, site, predominant symptoms, clinical debut, type of malformation, data associated with post therapy evolution, type of embolizing agent used, associated complications, Rankin scale, and death. Results: Data from 535 procedures was collected, we calculated an incidence of 4.4 cases per million inhabitants. Ninety procedures in 56 patients that used endovascular therapy were obtained with a female-male ratio of 0.75 and an age distribution of 35±14 (SD). A 36.3±11.5 (SD) mm diameter was registered. There was a 33% success rate for endovascular surgery. Conclusions: The multidisciplinary treatment of AVMs is made up of three pillar techniques: microsurgical resection, embolization, and radio-neurosurgery. It is extremely important to make an appropriate decision, with an emphasis on achieving better functional outcomes for the patient. Although neurological endovascular therapy was initially used as an adjuvant treatment for neurosurgery and radio-neurosurgery, it has been used more and more frequently as the first line of treatment.

• 환경영향평가
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• 제22권6호
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• pp.745-751
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• 2013

Environmental Specimen Banks (ESBs) have been established widely in the world since 1979 for monitoring long-term bio-accumulation of environmental pollutants. The ESBs perform the retrospective analysis of representative biological samples collected regularly and store them in cryogenic condition. In Korea, National Environmental Specimen Bank (NESB) was established in 2009. Since then, NESB had prepared the standard operating procedures (SOPs) for the seven kinds of specimens (Red Pine (Pinus densiflora), Common Carp (Cyprinus carpio), and etc.) for monitoring the effect of environmental pollution on the terrestrial ecosystem and river ecosystem. In 2012, NESB added Black-tailed Gull (Larus crassirostris)'s eggs to the list of the environmental specimen for monitoring marine environmental pollution. In this study, we sampled the eggs of the Black-tailed Gull on two islands (Baekryeongdo of the West Sea and Hongdo of the South Sea). Especially, we selected eggs which remained in the early stages of embryo development for certifying the consistent and stable monitoring for environmental pollutants in egg contents. However, it was not considered to classify an order of eggs per clutch in this study. It is known that the concentration variations of pollutants exist among eggs in one clutch. Therefore, it is needed to consider the positions of eggs in the laying sequences to meet the objective of bioaccumulation monitoring. We collected 30 eggs in each site but the amount may be insufficient to achieve storage target (over 2,000 g). Therefore, we need to consider an optimal sampling size.

• 분석과학
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• 제19권1호
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• pp.96-102
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• 2006

Trimethylamine(이하 TMA)은 물질특성상 시료의 채취 및 분석과 관련하여, 여러 가지 어려운 문제점들을 가지고 있다. 일반적으로 TMA의 채취방법으로 황산용액 흡수법이나 황산여과지 방법을 추천하고있다. 이들 방법은 아직까지 운용상 어려움과 분석시 숙련도를 요구한다. 본문에서는 보조적인 방법으로 Tedlar bag에 기초한 채취 및 SPME 를 이용한 분석기법의 특성에 대해 평가하고자 하였다. Tedlar bag은 시료의 채취 및 보관과 관련한 불안정성, 분석시 재현성 등에 대해 일부 문제점들이 지적받고 있다. 따라서 본 연구에서는 이런 문제점들을 여러 가지 기준으로 평가하고자 하였다. 이를 위해 다음과 같이 3가지 관점에서 비교실험을 수행하였다: (1) Tedlar bag에 TMA 시료를 보존할 때의 경시 변화, (2) Tedlar bag의 표면에 의한 TMA의 흡착 손실 정도, (3) SPME를 이용한 반복 분석시 파이버에 의한 시료의 흡착손실 등을 조사하였다. 최대 20일까지를 기준으로 경시 변화의 경향성을 조사한 결과, 48시간 까지 저농도에서 40~50% 정도로 시료의 감소가 일어났다. 그리고 두 가지 농도대에서 Tedlar bag 내부의 표면흡착에 의한 손실 여부를 평가한 결과, 저농도에서 약 20%, 고농도에서는 5% 이내의 손실을 확인하였다. 또한 동일한 Tedlar bag의 시료를 SPME로 반복분석한 결과, SPME fiber를 반복사용할 때 마다 백내부의 시료가 매회 2-3% 수준 감소하는 것을 확인할 수 있었다.

• 한국재난정보학회 논문집
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• 제8권3호
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• pp.304-309
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• 2012

국립환경과학원은 화학테러 사고 현장의 고체시료 사건원인 물질을 신속히 분석하고자 Portable FT-IR(Fourier Transform Infrared Spectroscopy, A2 Technologies, U.S.A.), Portable XRD(X-ray Diffraction, Olympus Innov-X co., U.S.A.) 등을 보유 및 운용하고 있다. Portable 분석장비의 효율적인 활용과 신속한 분석 값을 얻기 위해 사건현장에서의 탐지 및 시료채취, 현장분석 절차가 필요하다. Portable FT-IR, XRD의 분석결과 값의 정확도는 높으나, 사건현장 중심의 분석절차가 마련되지 않아 비상시 장비사용의 어려움을 가지고 있다. 이에 고체상 Portable 분석장비의 현장 분석방법 및 절차를 마련하여 현장대응에 적극 활용하고자 한다.

• 한국전문물리치료학회지
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• 제23권2호
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• pp.93-99
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• 2016

Background: Parametric statistical procedures are typically conducted under the condition in which a sample distribution is statistically identical with its population. In reality, investigators use inferential statistics to estimate parameters based on the sample drawn because population distributions are unknown. The uncertainty of limited data from the sample such as lack of sample size may be a challenge in most rehabilitation studies. Objects: The purpose of this study is to review the bootstrapping method to overcome shortcomings of limited sample size in rehabilitation studies. Methods: Articles were reviewed. Results: Bootstrapping method is a statistical procedure that permits the iterative re-sampling with replacement from a sample when the population distribution is unknown. This statistical procedure is to enhance the representativeness of the population being studied and to determine estimates of the parameters when sample size are too limited to generalize the study outcome to target population. The bootstrapping method would overcome limitations such as type II error resulting from small sample sizes. An application on a typical data of a study represented how to deal with challenges of estimating a parameter from small sample size and enhance the uncertainty with optimal confidence intervals and levels. Conclusion: Bootstrapping method may be an effective statistical procedure reducing the standard error of population parameters under the condition requiring both acceptable confidence intervals and confidence level (i.e., p=.05).

• Asian Pacific Journal of Cancer Prevention
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• 제14권4호
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• pp.2167-2172
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• 2013

Lung cancer remains a major cause of morbidity and mortality worldwide, accounting for more deaths than any other cause. All the clinical practice guidelines recommended against routine screening for lung cancer have cited lack of robust evidence, at least until a few years back. However, the potential to screen lung cancers has received renewed interest due to superior performance of low dose CT (LD-CT) in detecting early stage cancers. The incremental costs and risks involved due to the invasive procedures in the screened population due to a high false positivity rate questions the use of LD-CT scan as a reliable community based screening tool. There is therefore an urgent need to find a less invasive and a more reliable biomarker that is crucial to increase the probability of early lung cancer detection. This can truly make a difference in lung cancer survival and at the same time be more cost and resource utilization effective. Sampling blood serum being minimally invasive, low risk and providing an easy to obtain biofluid, needs to be explored for potential biomarkers. This review discusses the use of circulatory miRNAs that have been able to discriminate lung cancer patients from disease free controls. Several studies conducted recently suggest that circulating miRNAs may have promising future applications for screening and early detection of lung cancer.

• 한국토양비료학회지
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• 제46권5호
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• pp.313-321
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• 2013

The Average daily PET (Potential evapotranspiration), evaluated based on the last 30 years meteorological data and the lysimeter experiment carried out by RDA during 11 years, of 9 regions in Korea for the tomato cultivated in greenhouse, was $3.41mm\;day^{-1}$. Two kinds of water saving irrigation standard (WSIS), deficit irrigation standard (DIS) and partial root-zone drying irrigation standard (PRDIS) that include the irrigation interval and the amount of irrigation water according to the region, soil texture and growing stage, were established. According to the DIS and PRDIS, the cultivator can save water up to 29.2% and 53.7%, respectively, for tomato cultivation in greenhouse compared to the full irrigation standard (FIS) which established in 1999. WSIS can be used easily by the cultivator without complicate procedures such as soil sampling and measurement of soil water status by expensive sensors. But the cultivator should care about irrigation method such as PRDI (partial root-zone drying irrigation) without yield decrease.

• Smart Structures and Systems
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• 제14권6호
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• pp.1269-1289
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• 2014

With the sub-stepping technique, the numerical analysis in real-time dynamic hybrid testing is split into the response analysis and signal generation tasks. Two target computers that operate in real-time may be assigned to implement these two tasks, respectively, for fully extending the simulation scale of the numerical substructure. In this case, the integration time-step of solving the dynamic response of the numerical substructure can be dozens of times bigger than the sampling time-step of the controller. The time delay between the real and desired feedback forces becomes more striking, which challenges the well-developed delay compensation methods in real-time dynamic hybrid testing. This paper focuses on displacement prediction and force correction for delay compensation in the real-time dynamic hybrid testing with a large integration time-step. A new displacement prediction scheme is proposed based on recently-developed explicit integration algorithms and compared with several commonly-used prediction procedures. The evaluation of its prediction accuracy is carried out theoretically, numerically and experimentally. Results indicate that the accuracy and effectiveness of the proposed prediction method are of significance.

• 한국콘텐츠학회:학술대회논문집
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• 한국콘텐츠학회 2006년도 추계 종합학술대회 논문집
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• pp.124-128
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• 2006

본 연구는 지금까지 연구되어진 사회자본 척도에 대한 선행연구 고찰을 토대로 스포츠 참여자의 사회자본 척도를 개발하는데 그 목적이 있다. 이와 같은 목적을 달성하기 위해 다양한 사회자본 척도 가운데 Fukuyama(1996), Shane(2005), 김정란(2003), 박희봉과 김명환(2000), 정기환과 심재만(2004)의 SC를 토대로 스포츠 참여자의 사회자본 척도(SCSPS)를 개발하였으며, 본 연구에서 도출된 결과는 다음과 같다. 첫째, 개발된 스포츠 참여자의 사회자본 척도(SCSPS)는 연결망, 규범, 신뢰, 지식공유, 지위향상 등 5개의 속성으로 구분되었다. 둘째, 개발된 스포츠 참여자의 사회자본 척도(SCSPS)를 구조방정식모형(SEM)을 이용하여 분석한 결과 연구자가 설정한 부합지수 기준에 적합하였다. 셋째, 스포츠 참여자의 사회자본 척도(SCSPS)는 신뢰도와 타당도 검증에 있어 양호한 것으로 나타났다.

• 한국토양비료학회지
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• 제50권2호
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• pp.100-105
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• 2017

Various methods for assessing soil total nitrogen (TN) and inorganic N content have been developed to manage nutrient and to understand N cycle in soil. This paper address the technical procedures in arable soil samples to conduct soil sampling, sample preparation, and measuring total N and inorganic N. Among various methods for measuring soil total nitrogen contents, Kjeldahl distillation and Indophenol blue method have widely used due to reliability and economic advances. Also, two methods can analyze more samples at the same time compared with other nitrogen measuring methods. For evaluating inorganic N content, mainly in forms of nitrate-N ($NO_3{^-}-N$) and ammonium-N ($NH_4{^+}-N$), extraction with a single reagent such as 2M KCl has been employed, followed by Kjeldahl distillation or indophenol blue methods.