• Title/Summary/Keyword: Sample testing

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Probability of Rejection Curve for Equivalence Testing Procedure

  • Sung, Nae Kyung
    • Journal of Korean Society for Quality Management
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    • v.22 no.4
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    • pp.102-110
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    • 1994
  • We investigate the small-sample behavior of the probability of rejection curves and its performance for a equivalence testing procedure based on confidence intervals which was developed with a motivation from bioequivalence studies. This type of equivalence studies are conducted frequently in pharmaceutical industries to compare the relative bioavailabilty of two formulations of a drug and can be applied various fields where assurance of quality equivalence is needed. From the Monte-Carlo simulation results we suggest proper sample sizes for the equivalence testing procedure.

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Analysis of a Queueing Model with a Two-stage Group-testing Policy (이단계 그룹검사를 갖는 대기행렬모형의 분석)

  • Won Seok Yang
    • Journal of Korean Society of Industrial and Systems Engineering
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    • v.45 no.4
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    • pp.53-60
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    • 2022
  • In a group-testing method, instead of testing a sample, for example, blood individually, a batch of samples are pooled and tested simultaneously. If the pooled test is positive (or defective), each sample is tested individually. However, if negative (or good), the test is terminated at one pooled test because all samples in the batch are negative. This paper considers a queueing system with a two-stage group-testing policy. Samples arrive at the system according to a Poisson process. The system has a single server which starts a two-stage group test in a batch whenever the number of samples in the system reaches exactly a predetermined size. In the first stage, samples are pooled and tested simultaneously. If the pooled test is negative, the test is terminated. However, if positive, the samples are divided into two equally sized subgroups and each subgroup is applied to a group test in the second stage, respectively. The server performs pooled tests and individual tests sequentially. The testing time of a sample and a batch follow general distributions, respectively. In this paper, we derive the steady-state probability generating function of the system size at an arbitrary time, applying a bulk queuing model. In addition, we present queuing performance metrics such as the offered load, output rate, allowable input rate, and mean waiting time. In numerical examples with various prevalence rates, we show that the second-stage group-testing system can be more efficient than a one-stage group-testing system or an individual-testing system in terms of the allowable input rates and the waiting time. The two-stage group-testing system considered in this paper is very simple, so it is expected to be applicable in the field of COVID-19.

A Study on the Determination of the Economic Sample Size of the Attribute Acceptance Sampling Plans for Destructive Testing (파괴시험 계수형 샘플링검사 경제적 시료 크기 결정에 관한 연구)

  • 김병재
    • Journal of Korean Society of Industrial and Systems Engineering
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    • v.4 no.5
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    • pp.11-14
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    • 1981
  • This study intends to decide the economic sample size based on the cost of sampling Inspection for destructive testing. The marginal percent defective is used as the lot tolerance percent defective (LTPD), and the Newton's iterative method is adopted to calculate the optimum sample size(n), given by the consumer's risk($\beta$ - risk) and the acceptance number(c).

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Comparison of Probability of Detecting Bluetongue in Quarantine Testing for the Imported Cattle with Special Focus on the Sampling Scenario (수입 소의 검역검사 수준에 따른 블루텅 검출 확률 비교)

  • Pak, Son-Il
    • Journal of Veterinary Clinics
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    • v.27 no.4
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    • pp.421-426
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    • 2010
  • In view of free from bluetongue (BT) in the domestic cattle population in Korea, the key of quarantine testing for BT virus (BTV) infection is detection of cattle previously exposed to the virus. The objective of this study was to estimate the probability of detecting a cattle infected with BTV using a stochastic modeling analysis of existing quarantine testing data. Three testing scenarios were considered in this study: serological testing of all animals in all imported lots (scenario 1), serological testing of a sample of cattle from all imported lots (scenario 2), and serological testing of 50% of imported lots (scenario 3). In scenario 2 and 3, it was assumed that cattle were sampled (sample size) within each lot to detect 5% of the cattle in each lot with a 95% confidence, taking into account diagnostic sensitivity of the ELISA (enzyme-linked immunosorbent assay). The model output was the total number of BTV-infected cattle and the prevalence of BTV infection in imported cattle from the US, Australia, Canada and Japan. Compared to the scenario 1, the probability of detecting a BTV-infected cattle was estimated to be 19% and 1.6% in scenario 2 and 3, respectively. Furthermore, the analyses showed a 95% confidence that BTV prevalence was less or equal to $9.7{\times}10^{-4}$ (median = $1.5{\times}10^{-5}$), indicating that, for the scenario 2 and 3 with serological testing for a sample of cattle, the risk of introducing an exotic strain of BTV into Korea through the importation of live cattle would not be acceptable.

Novel Convenient Method to Determine Wettability and Dispersibility of Dairy Powders

  • Lee, Jeae;Chai, Changhoon;Park, Dong June;Lim, Kwangsei;Imm, Jee-Young
    • Food Science of Animal Resources
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    • v.34 no.6
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    • pp.852-857
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    • 2014
  • This study was carried out to develop a simple, convenient, and reproducible testing device to determine wettability and dispersibility of dairy powders. The testing device consists of a sieve ($150{\mu}m$) attached to a sample chamber, sensors mounted on a supporting body and a main control unit containing a display panel. The sensors detect the difference in electrical resistance between air and water. A timer is automatically triggered by the sensor when the bottom of sample-loaded chamber contacts water in the petri dish. Wettability and dispersibility of commercial skim milk powders (SMPs) produced at different heating strengths (low-, medium-, and high-heat SMP) are compared using the new testing device. Wettability of the SMPs were correlated with particle size and are found to increase in the order of medium-, low-, and high-heat SMP regardless of the amount of sample tested. Dispersibility of SMPs showed the same trend and high heat-SMP which has the smallest particle size resulted in the lowest dispersibility. Unlike existing methods, the new testing device can determine both wettability and dispersibility of powders and successfully detected differences among the samples.

Evaluation of Whole Effluent Toxicity (WET) Proficiency Testing for Water Quality Measurement Agencies in Korea (국내 수질측정대행업에 대한 생태독성 숙련도시험 평가)

  • Park, Woo Sang;Kim, Sang Hun
    • Journal of Korean Society on Water Environment
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    • v.29 no.4
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    • pp.568-573
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    • 2013
  • In this study, we conducted whole effluent toxicity (WET) proficiency testing based on the results which $EC_{50}$ value of 3 types (A, B, C) unknown samples calculated from 32 water quality measurement agencies in Korea. WET proficiency testing was expected to their improve of analysis skill and ensure reliability of analysis results. Ultimately, it is intended to promote the reliable enforcement of WET. WET proficiency testing was evaluated using the z-score, robust z-score and the results showed that 30 participating agencies were "compliance". In addition, $EC_{50}$ values of "unknown sample A" were the normal distribution. Therefore, "unknown sample A" was considered as the most suitable standard toxicity substance.

A Study for Improvement of the Testing Methods for Quality Control of Recycled Aggregate (순환골재의 품질평가를 위한 시험방법 개선에 관한 실험적 연구)

  • Jaung, Jae-Dong;Lee, Do-Heun
    • Journal of the Korea Institute of Building Construction
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    • v.8 no.4
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    • pp.105-114
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    • 2008
  • This study investigates the saturation level of surface dryness, quantity of adhesive mortar, and the alien substance content of recycled aggregates for concrete to develop an adequate quality testing method for understanding the properties of recycled aggregates, which differ greatly from preexisting aggregates. For tests that measure the saturation level of surface dryness, where detail methods are applied differently according to the tester, various testing methods from across world were compared and analyzed. This study revealed that when measuring the saturation level of surface dryness of a certain sample, aggregates must be supplemented immediately whenever the height of the sample becomes lower than the measuring mold, and allowing the tamper to free fall on the sample will provide the most accurate results. When measuring the quantity of adhesive mortar of recycled aggregates for concrete, an acid solution was used, and since the quantity of adhesive mortar increases as the particle sizes gets smaller, the sample for testing should represent the entire granularity. Sulfuric acid solution is adequate for immersion, and the concentration should be 20% for best results. According to the alien substance content measurement, which was examined by the naked eye, the error range caused by the difference in particle size was neglectable, and therefore the sample should be $2.5{\sim}5.0mm$ in size concerning the accuracy and measuring time. Also, for coarse recycled aggregates, the sample should amount to 1kg for measuring alien substance content by the naked eye, which proves that assortment by the naked eye is the most adequate method for measuring the alien substance content of a recycled aggregate.

Equivalence Testing as an Alternative to Significance Testing

  • Huh, Myung-Hoe
    • Journal of the Korean Statistical Society
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    • v.23 no.1
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    • pp.199-206
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    • 1994
  • Sometimes a researcher with a view of conventional significance testing rejects his/her hypothesis, even through it could have not been rejected with a smaller sample. This can be a logical dilemma for a researcher who wants to "prove" a hypothesis rather than to show discrepancy from a null hypothesis. In this study, a new testing paradigm called equivalence testing via confidence interval will be developed so that it is suitable for the purpose of statistical proof.cal proof.

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Utilization of Soymilk Residue for Wheat Doenjang (밀가루 고오지에 의한 두유박이용 밀된장 제조)

  • Kim, Ze-Uook;Bang, Chan-Sik;Choi, Jun-Bong;Lim, Chun-Son
    • Applied Biological Chemistry
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    • v.32 no.4
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    • pp.357-361
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    • 1989
  • Wheat Doenjang was manufactured by mixing various ratio of the soymilk residue with wheat Koji. As the result, the content of reducing sugar was increased till 50 days and decreased thereafter during aging of the mash. As the combination ratio of soymilk residue was increased, the content of reducing sugar was decreased and amino nitrogen content was increased prominently till 50 days in all testing samples but thereafter the increasing ratio was slowdowned. At the beginning of the aging the content of the amino nitrogen was higher in the testing sample which had higher combination ratio of soymilk residue but at the end of the aging the result was reversed. The content of the total acids was increased prominently till 40 days but thereafter the increasing ratio was slowdowned, and in each testing samples the difference in total acid content was extremely slight. In the color of each testing samples aged 80 days as the combination ratio of soymilk residue was increased, the lightness was increased, and the redness was decreased but the yellowness was increased. From the result of sensory evaluation test of wheat Doenjang aged 90 days, soy sprout Doenjang soup showed the best taste in control and as the combination ratio of soymilk residue was increased, the taste was dropped slightly but no significant differences was obtained among the testing sample A,B and C but between control and testing sample D there was significant difference. In the original taste of Doenjang, the control was the best and as the combination ratio of soymilk residue increased, the point was dropped but there were no significant differences between control and testing sample A and testing sample B and C.

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Computer Adaptive Testing Method for Measuring Disability in Patients With Back Pain

  • Choi, Bongsam
    • Physical Therapy Korea
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    • v.19 no.3
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    • pp.124-131
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    • 2012
  • Most conventional instruments measuring disability rely on total score by simply adding individual item responses, which is dependent on the items chosen to represent the underlying construct (test-dependent) and a test statistic, such as coefficient alpha for the estimate of reliability, varying from sample to sample (sample-dependent). By contrast, item response theory (IRT) method focuses on the psychometric properties of the test items instead of the instrument as a whole. By estimating probability that a respondent will select a particular rating for an item, item difficulty and person ability (or disability) can be placed on same linear continuum. These estimates are invariant regardless of the item used (test-free measurement) and the ability of sample applied (sample-free measurement). These advantages of IRT allow the creation of invariantly calibrated large item banks that precisely discriminate the disability levels of individuals. Computer adaptive testing (CAT) method often requiring a testing algorithm promise a means for administering items in a way that is both efficient and precise. This method permits selectively administering items that are closely matched to the ability level of individuals (measurement precision) and measuring the ability without the loss of precision provided by the full item bank (measurement efficiency). These measurement properties can reasonably be achieved using IRT and CAT method. This article aims to investigate comprehensive overview of the existing disability instrument for back pain and to inform physical therapists of an alternative innovative way overcoming the shortcomings of conventional disability instruments. An understanding of IRT and CAT method will equip physical therapist with skills in interpreting the measurement properties of disability instruments developed using the methods.