• 대한치과교정학회지
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• 제34권4호
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• pp.313-324
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• 2004

본 연구에서는 성장기 골격성 III급 부정 교합 한자의 치료 전 측모 두부방사선 계측사진에서 얻을 수 있는 골격성, 치성 분석을 통하여 안정군과 재발군을 구별하여 주는 요소를 찾아보아 III급 부절 교합의 치료시 안정성을 고려한 치료 선택에 도움을 주고자 하였다 고정식 교정 장치를 통한 전치부 반대 교합 혹은 절단 교합의 골격성 III급 부정 교합 치료 후 최소 1년 동안 안정된 결과를 보인 안정군 33명과 관찰 기간 동안 절단 교합 이하의 수평 피개를 보인 재발군 22명을 연구 대상으로 하여 비교하였으며 t-test를 시행하여 다음과 같은 결론을 얻었다. 1. 건후방적 골격 형태보다는 수직적 형태, 특히 AB-maxillo-mandibular triangle내의 수직적 형태가 III급 부정 교합치료의 예후에 주요한 결정 인자로 나타났다. 수직 각도 계측 항목에 의한 안정군과 재발군간의 비교에서 유의성 있는 차이를 보인 항목은 AB-MP, ODI로 나타났다(P<0.01). 수직 비율 계측 항목에서도 MP-P/AL, PP-P/AL항목이 유의성 있는 차이를 보였다(P<0.05). 2. 재발의 경향은 교합 평면 특히. 하악 교합 평면이 전하방으로 급경사를 이룰수록 증가했다. 친합 평면 경사도와 관련된 계측 항목에 의한 안정군과 재발군간의 비교에서 OP(L)-PP, OP-PP, AB-OP(L), Wits appraisal항목이 유의성 있는 차이를 보였다(P<0.05). 본 연구는 전후방 부조화가 아닌 골격성, 치성 수직 부조화가 재발을 예측하는 적절한 기준이 됨을 시사하였다.

• 한국버섯학회지
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• 제18권1호
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• pp.115-119
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• 2020

느타리버섯 곤지7호의 수확 후 CO₂ 처리에 의한 품질 유지 효과 및 적정 처리 농도를 구명하고자 연구를 수행하였다. 수확한 버섯을 3℃에서 1일간 예냉 후에 CO₂ 농도 0, 30 및 50%에서 3시간 처리한 다음 20 ㎛ 두께 OPP필름 봉지에 밀봉하여 3℃에 21일 저장하였다. 30% CO₂ 처리에서 대조직의 경도가 저장 21일까지 높게 유지되었고, 대조직의 색은 명도(CIE L^⁎값)가 30% CO₂ 처리한 느타리버섯이 저장 14일, 21일에 높고 황색도(CIE b^⁎값)가 저장 2일, 7일에 낮게 나타났으며 외관품위가 저장 7일부터 저장기간 내내 대조구와 50% CO₂ 처리에 비해 높았으며 3℃ 저장 중 17일까지 느타리버섯 곤지7호의 상품성을 유지하였다. 30% CO₂ 농도로 3시간 처리가 느타리버섯 곤지7호의 저온저장 중 품질 유지기간을 연장할 수 있는 수확 후 처리방법으로 판단되었다.

• 핵의학기술
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• 제18권1호
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• pp.153-157
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• 2014

Anti double-stranded DNA (Anti-ds DNA)항체의 검출은 SLE의 진단에 중요하며 American College of Rheumatologists의 SLE 진단기준에 포함되어 있다. 또한 SLE 질병의 활성도와 Anti-ds DNA 항체 수준의 상관성이 보고되어 있으며 Anti-ds DNA 항체 정량검사는 SLE의 치료 전, 후 추적에 매우 유용하다. Anti-ds DNA 항체의 검출을 위한 검사 방법으로 방사면역측정법(radioimmunoassay, RIA)을 이용한 Farr assay, Crithidia luciliae를 이용한 면역형광 측정법(immunofluorescence Test, CLIFT), 효소면역측정법(enzyme-linked immunosorbent assay, ELISA), 화학발광면역 측정법(chemiluminescence immunoassay, CLIA)이 있다. 본원에서 방사면역측정법(radioimmunoassay, RIA)으로 Anti-ds DNA 항체 검사 과정에서 lipemic한 검체의 경우 침전물의 형성이 원활하지 않거나 침전물도 같이 흡입되는 상황이 발생 하였고, 이러한 문제점을 해결하기 위해 lipemic 검체가 분석 결과에 미치는 영향 정도를 평가하였다. 2012년 9월부터 2013년 2월까지 Anti-ds DNA 항체 검사가 의뢰된 검체 중 lipemic한 검체(n=81)를 선택하여 마이크로 원심분리기로 전처리(고속 원심분리: 14,000 rpm 5 mins)한 후 동시에 Anti-ds DNA 항체 검사(Anti-ds DNA kit, Trinity Biotech, Ireland)를 시행하였다. 실험군 1 (lipemic 검체의 Anti-ds DNA 항체 농도 ${\leq}7IU/mL$)에서 y=0.3636x+4.7322, $R^2=0.0238$, Pearson 상관계수는 0.154, paired t-test (P=0.003), Difference (%) mean 65.7의 결과를 얻었으며 통계적으로 유의한 차이를 보였다. 그러나 실험군 2 (lipemic 검체의 Anti-ds DNA 항체 농도 ${\geq}8IU/mL$)에서 y=0.9837x+0.2982, $R^2=0.994$, Pearson 상관계수는 0.997, paired t-test (P=0.181), Difference (%) mean -5.53을 보였고 통계적으로 유의한 차이가 없음을 확인할 수 있었다. 임상에서 SLE (systemic lupus erythematosus)의 진단에 중요한 역할을 하는 Anti-ds DNA 항체 검사는 lipemic 검체의 영향을 배제하기 위해서 반드시 전처리(고속 원심분리: 14,000 rpm 5 mins) 과정을 통해 혈청 내 지질 성분을 제거한 후 검사를 시행하여야 한다.

• Journal of Acupuncture Research
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• 제29권1호
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• pp.89-101
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• 2012

Objectives : The purpose of this study was find out the therapeutic effects of its exclusive use on the rat with allergic rhinitis. Materials and Methods : Thirty Sprague-Dawley rats were divided into three group : normal group, control group and sample group. To induce the allergic rhinitis in control group and sample group, rats were sensitized intraperitoneally with 0.1% ovalumin solution 3 times at intervals of 1 week. Then intranasal sensitization was performed by diffusing 0.1% ovalumin solution 3 times at intervals of 2 days. After that time, rats in the sample group were administered by $Yonghyang$($LI_{20}$) subcutaneously to treat the inflammation. Results : 1. The anti-oxidant effects of $Hwangryunhaedok-tang$ extract was dose-dependantly increased. 2. The RAW 264.7 cells were treated with LPS for 1 hours prior to the addition of indicated concentrations ($0.4,-1.0mg/m{\ell}$) of HHT, and the cells were further incubated for 24 hours. The LPS-induced iNOS mRNA expression and NO production were dose-dependantly decreased in HHT treated RAW 264.7 cells. 3. The number of eosinophil in HP noticeably decreased than CON and this decrease had probability. The infiltration of eosinophil in HP noticeably decreased than CON. 4. The damaged mucosa as disruption of cilia in respiratory cell and vacant mucose secreting cell were increased CON, but HP same as normal configuration. Decrease of PAS positive cell were shown in CON, but goblet cell occupied with neutral mucous were shown in HP. Decrease of mucosal stress(HSP70). Decrease of perennial sign(PPAR-${\gamma}$). Decrease of icthing and sneezing intricate neurotransmitter-(substance P). 5. The anti-inflammation of HHT pharmacopuncture for AR caused mucosa comes to result as belows. Decrease of pre-inflammation cytokine(TNF-${\alpha}$). Decrease of transcription factor (NF-${\kappa}B$ p65). Decrease of transcription factor inhibitor(p-$I{\kappa}B$). Decrease of inflammation cytokine(iNOS). Conclusions : The results may suggest that administration treatment using $Hwangryunhaedok-tang$ pharmacopucnture decreases the inflammatory response on an animal model with allergic rhinitis.

• 한국식품과학회지
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• 제31권6호
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• pp.1557-1562
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• 1999

건멸치의 저장법 개발을 위한 일련의 연구로써 건멸치의 흡습특성을 조사하고, 선택된 포장조건에서 위생화에 필요한 5 kGy의 감마선을 처리한 다음 저장성 예측시험을 수행하였다. 건멸치의 등온흡습곡선으로부터 구한 BET 단분자층 수분함량은 5.47%, 이에 해당되는 수분활성은 0.15로써 품질안정성을 유지하기 위해서는 낮은 수분활성의 유지와 방습 포장이 필요한 것으로 나타났다. 폴리에틸렌필름(0.1 mm)과 접합필름(nylon/polyethylene, NY/PE)으로 포장된 건멸치에 5 kGy의 감마선을 조사한 다음 $15^{\circ}C/68%\;RH,\;25^{\circ}C/75%RH$ 및 $35^{\circ}C/84%$ RH의 조건에 각각 저장하면서 품질변화를 측정하였다. 건멸치 품질지표성분으로 확인된 갈변반응과 관능적 기호도 변화의 속도상수는 저장온도에 비례하여 포장재와 감마선 조사에 따라 $2.17{\sim}2.40$범위의 온도계수$(Q_{10})$를 나타내었다. 그리고 25℃에서의 shelf-life는 비조사구의 PE와 NY/PE 포장이 각각 84일과 125일, 감마선 조사구(5 kGy)의 PE와 NY/PE 포장은 각각 126일과 138일로 나타나, 적정선량의 감마선 조사와 접합포장재의 사용은 건멸치의 위생적 품질개선은 물론 저장성 향상에도 효과적으로 나타났다.

• 한국임상보건과학회지
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• 제5권1호
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• pp.790-802
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• 2017

Purpose. This study was designed to analyze recent trends in Children Art Therapy Program Intervention research in Korea and suggest future research directions in this area. Methods. Studies(29) selected from http://www.riss4u.net for last 15 year were used. They were analyzed by publication type, field and design of the study, study participants and outcome variables used in intervention studies. Results. 1. As for academic field, there are 15 art therapy academic journals(51.72%), which made up the largest proportion. 2. As for subjects of the study, there are 17 articles of Elementary (58.6%) education, which made up the largest proportion. As for the subjects of sex, 8 articles (27.59%) are for male students, 7 (24.14%) articles are for female students and 14 articles (48.28.%) are for both male and female students. 3. As for 7 articles of Art therapy(24.14%), 7 articles of Group Art therapy (24.14%) made up the largest proporton 4. As for the intervention study method according to the subjects of suicide intervention program, there are 15 articles of monoclonal Pre and post design (51.72%),which made up the largest proportion. 5. As for the sample size, there were 16.79 persons in the treatment group on average, 13.28 persons in the control group have average and the total persons were 10 on average. The treatment period was 12 weeks on average and the average number of treatment times was 18. The places of treatment were 3 schools (10.38%), which made up the largest proportion. 19. The results of the experimental study support the research hypothesis of all 29 programs. Conclusions. As the above, the studies on the art therapy intervention program for children are increasing but the subjects are overly weighted toward elementary school students. Although the content of the art therapy intervention program was varied, it was found that the development of the program using various art media which can induce the motivation of the child was lacking. In addition, the place of experimental mediation was concentrated on psychology center as 12(41.38%), indicating that there are not enough places to connect with community organizations such as schools and hospitals. The variables of experimental study were focused on psychological variables and it was found that there were insufficient application of various variables including coping method, social support, and physiological variables.

• 대한한방내과학회지
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• 제26권3호
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• pp.660-669
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• 2005

Objectives : The aim of this study is to find the acoustic characteristics of acupuncture therapy effects on post-stroke dysarthria. Methods : Acupuncture therapy was applied for four to six weeks by inserting needles into eight acupuncture points, CV23, CV24, bilateral 'Sheyu' and ipsilateral ST4, ST6 and contralateral LI4, ST36 on facial palsy side. All the speech samples were collected, pre-treatment and post-treatment, using Computerized Speech Lab. VOT and TD of each speech sample and vowel formant(F1&F2) were analyzed on spectrogram. Result : VOT and TD were decreased after treatment. F1 was decreased, and F2 was increased after treatment. Conclusions : This suggests that acupuncture therapy improves symptoms of post-stroke dysarthria by stimulating articulation organs such as tongue, lips, cheeks, larynx and pharynx.

• Journal of Korean Dental Science
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• 제7권1호
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• pp.6-15
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• 2014

Purpose: The purpose of this retrospective study is to investigate the degree of coincidence between the peer assessment rating (PAR) index and American Board of Orthodontics objective grading system (ABO-OGS) in the assessment of orthodontic treatment outcomes of Class I malocclusion cases. Materials and Methods: The sample consisted of 26 Class I patients. The PAR index was used for evaluation of pre-(T0) and posttreatment (T1) casts, and the ABO-OGS for assessment of T1 casts. If there was a reduction in PAR scores from T0 to T1 of more than 30%, the label 'PAR+' was given to the case, and if not, it was labeled 'PAR-'. If the ABO-OGS was less than 27, the label 'OGS+' was given to the case and if not, it was labeled 'OGS-'. 'A PAR-only qualified group' (PAR+), 'ABO-OGS-only qualified group' (OGS+), 'both indices qualified group' (PAR+/OGS+), and 'both indices disqualified group' (PAR-/OGS-) were compared with a Wilcoxon rank-sum test, sensitivity/specifi city test and Spearman's correlation test. Result: PAR scores for T0, T1, and percentage reduction were 21.1, 6.4, and 65.9%, respectively, and 35.4 for ABOOGS. The distribution of the 'PAR+/OGS+', 'PAR+', and 'PAR-/OGS-' group was 19.3%, 76.9%, and 3.8%, respectively. The T0-PAR, T1-PAR and PAR point reductions for the 'PAR+' group were significantly higher than those of 'PAR+/OGS+' groups (23.1 vs. 15.6; 6.7 vs. 4.6; and 16.5 vs. 11.0; all P<0.05). However, the PAR-percentage reduction and treatment duration between the two groups were not statistically different (70.0% vs. 67.0%, P=0.4325; 24.1 months vs. 25.0 months, P=0.4057). The T1-ABO-OGS score for 'PAR+' group was significantly higher than that of the 'PAR+/OGS+' groups (38.2 vs. 24.0, P<0.001). Conclusion: Since the fraction of the 'PAR+/OGS+' group was less than 20% and there was no significant correlation between PAR-percentage reduction and T1-ABO-OGS, development of a new index system for the accurate evaluation of treatment outcome is needed.

• Asian-Australasian Journal of Animal Sciences
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• 제26권4호
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• pp.537-544
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• 2013

This study examined whether pre-treating palm kernel expeller (PKE) with exogenous enzyme would degrade its fiber content; thus improving its metabolizable energy (ME), growth performance, villus height and digesta viscosity in broiler chickens fed diets containing PKE. Our results showed that enzyme treatment decreased (p<0.05) hemicellulose and cellulose contents of PKE by 26.26 and 32.62%, respectively; and improved true ME (TME) and its nitrogen corrected value ($TME_n$) by 38% and 33%, respectively, compared to the raw sample. Average daily gain (ADG), feed intake and feed conversion ratio (FCR) of chickens fed on different dietary treatments in the grower period were not significantly different. Although there was no difference in feed intake (p>0.05) among treatment groups in the finisher period, ADG of chickens in the control (PKE-free diet) was higher (p<0.05) than in all treatment groups fed either 20 or 30% PKE, irrespective of with or without enzyme treatment. However, ADG of birds fed with 20% PKE was higher than those fed with 30% PKE. The FCR of chickens in the control was the lowest (2.20) but not significantly different from those fed 20% PKE diets while birds in the 30% PKE diets recorded higher (p>0.05) FCR. The intestinal villus height and crypt depth (duodenum, jejunum and ileum) were not different (p>0.05) among treatments except for duodenal crypt depth. The villus height and crypt depth of birds in enzyme treated PKE diets were higher (p<0.05) than those in the raw PKE groups. Viscosity of the intestinal digesta was not different (p>0.05) among treatments. Results of this study suggest that exogenous enzyme is effective in hydrolyzing the fiber (hemicellulose and cellulose) component and improved the ME values of PKE, however, the above positive effects were not reflected in the growth performance in broiler chickens fed the enzyme treated PKE compared to those received raw PKE. The results suggest that PKE can be included up to 5% in the grower diet and 20% in the finisher diet without any significant negative effect on FCR in broiler chickens.

• 대한통합의학회지
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• 제12권3호
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• pp.37-47
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• 2024

Purpose : Cancer survivors often suffer from postoperative sequelae. the diagnosing and provision of manual therapy using spiral taping significantly improves the quality of life of cancer patients. The aim of this case study is to investigate the immediate effects of spiral taping on pain, range of motion (ROM), chemotherapy-induced peripheral neuropathy (CIPN), and lymphedema following breast cancer surgery. Methods : The taping techniques were performed as follows by spiral taping. The measurements were taken before, in the middle, and after taping using a mobile phone camera, tape measure, and a numerical rating score (NRS). The evaluation employed a single-group pre-post design based on a primitive experimental design. Results : Out of four patients, all four exhibited Reverse circle flow energy (RCFE), Passive cervical right (Rt) rotation test, anterior-posterior movement pattern, nerve type (+), cold energy (CE), sangcho acupuncture point, blood clot, hwal point. Comparing before and after treatment, almost all values were reduced to zero after treatment in terms of pain complaints. The lack of range of motion (ROM) caused by the shortened tissue after surgery did not increase. The range of motion (ROM) lost due to pain returned to normal. The circumference of lymphedema did not show a tendency. The symptoms of CIPN improved. Conclusion : There was a significant change in joint range of motion, with pain decreasing, but there were structural limitations in the tissue due to total resection, and the chemotherapy-induced peripheral neuropathy scale. It was effectively treated surgical site pain, axillary membrane syndrome-induced pain, and unexplained pain. While there was a treatment effect for lymphedema in the evaluation of circumference values, there was no significant change in circumference. There was a significant effect on chemotherapy-induced peripheral neuropathy, particularly in treating numbness in the feet, which is a side effect of TC anticancer drugs. This case study found that spiral balance taping provides a rapid therapeutic effect for most side effects in patients who have undergone total breast cancer resection. However, the generalization is limited due to the small sample size, and further research is needed to determine the extent to which the effects of one treatment are maintained.