• 제목/요약/키워드: Sample matrix

검색결과 700건 처리시간 0.034초

IHP 알고리즘을 이용한 SIMO 시스템용 적응 직접 결정 등화기 연구 (An Adaptive Decision-Directed Equalizer using Iterative Hyperplane Projection for SIMO systems)

  • 이원철
    • 한국통신학회논문지
    • /
    • 제30권1C호
    • /
    • pp.82-91
    • /
    • 2005
  • 본 논문은 iterative hyperplane projection 을 이용한 효율적인 APA(affine projection algorithm)을 소개한다. 다양한 적응 알고리즘들 중 APA는 랭크 부족 문제를 해결하며 고속 수렴의 특성 때문에 다양한 응용분야에 적용되고 있다. SIMO(Single-Input-Multiple-Output) 시스템을 위한 STDE(Space-Time Decision- directed Equalizer) 적용 시 흔히 단일 채널 환경에서 발생하는 "shifting invariance property"를 이용할 수 없으므로 인해 FTF(Fast Transversal Filter)와 같이 저 복잡도를 갖는 고속 적응 알고리즘을 사용할 수 없다. 따라서 APA 기반의 STDE 기능을 수행하는 과정에서 SMI(Sample Matrix Inversion) 처리가 불가피하며, 계산상의 복잡도가 증가하게 된다. 이러한 문제점을 해결하고자 본 논문에서는 APA 기법 고유의 우수한 추적 특성 및 고속 수렴 성질을 유지하면서, 낮은 복잡도를 갖는 IHP(Iterative Hyperplane Projection) 알고리즘 기반의 효율적인 수정 APA 기법을 소개한다. 제안된 IHP 기반 APA 기법의 성능을 확인하기 위하여, 무선 SIMO 채널 환경 하에서 제안된 IHP-APA 알고리즘을 적용한 STED에 대한 비트 에러 오률 (BER) 특성과 계산량 분석을 통해서 우수성을 입증하였다.

Creating Subnetworks from Transcriptomic Data on Central Nervous System Diseases Informed by a Massive Transcriptomic Network

  • Feng, Yaping;Syrkin-Nikolau, Judith A.;Wurtele, Eve S.
    • Interdisciplinary Bio Central
    • /
    • 제5권1호
    • /
    • pp.1.1-1.8
    • /
    • 2013
  • High quality publicly-available transcriptomic data representing relationships in gene expression across a diverse set of biological conditions is used as a context network to explore transcriptomics of the CNS. The context network, 18367Hu-matrix, contains pairwise Pearson correlations for 22,215 human genes across18,637 human tissue samples1. To do this, we compute a network derived from biological samples from CNS cells and tissues, calculate clusters of co-expressed genes from this network, and compare the significance of these to clusters derived from the larger 18367Hu-matrix network. Sorting and visualization uses the publicly available software, MetaOmGraph (http://www.metnetdb.org/MetNet_MetaOm-Graph.htm). This identifies genes that characterize particular disease conditions. Specifically, differences in gene expression within and between two designations of glial cancer, astrocytoma and glioblastoma, are evaluated in the context of the broader network. Such gene groups, which we term outlier-networks, tease out abnormally expressed genes and the samples in which this expression occurs. This approach distinguishes 48 subnetworks of outlier genes associated with astrocytoma and glioblastoma. As a case study, we investigate the relationships among the genes of a small astrocytoma-only subnetwork. This astrocytoma-only subnetwork consists of SVEP1, IGF1, CHRNA3, and SPAG6. All of these genes are highly coexpressed in a single sample of anaplastic astrocytoma tumor (grade III) and a sample of juvenile pilocytic astrocytoma. Three of these genes are also associated with nicotine. This data lead us to formulate a testable hypothesis that this astrocytoma outlier-network provides a link between some gliomas/astrocytomas and nicotine.

Rapid Identification of Staphylococcus Species Isolated from Food Samples by Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry

  • Kim, Eiseul;Kim, Hyun-Joong;Yang, Seung-Min;Kim, Chang-Gyeom;Choo, Dong-Won;Kim, Hae-Yeong
    • Journal of Microbiology and Biotechnology
    • /
    • 제29권4호
    • /
    • pp.548-557
    • /
    • 2019
  • Staphylococcus species have a ubiquitous habitat in a wide range of foods, thus the ability to identify staphylococci at the species level is critical in the food industry. In this study, we performed rapid identification of Staphylococcus species using Matrix-Assisted Laser Desorption/Ionization Time-of-Flight mass spectrometry (MALDI-TOF MS). MALDI-TOF MS was evaluated for the identification of Staphylococcus reference strains (n = 19) and isolates (n = 96) from various foods with consideration for the impact of sample preparation methods and incubation period. Additionally, the spectra of isolated Staphylococcus strains were analyzed using principal component analysis (PCA) and a main spectra profile (MSP)-based dendrogram. MALDI-TOF MS accurately identified Staphylococcus reference strains and isolated strains: the highest performance was by the EX method (83.3~89.5% accuracy) at species level identification (EDT, 70.3~78.9% accuracy; DT, less than 46.3~63.2% accuracy) of 24-h cultured colonies. Identification results at the genus level were 100% accurate at EDT, EX sample preparation and 24-h incubation time. On the other hand, the DT method showed relatively low identification accuracy in all extraction methods and incubation times. The analyzed spectra and MSP-based dendrogram showed that the isolated Staphylococcus strains were characterized at the species level. The performance analysis of MALDI-TOF MS shows the method has the potential ability to discriminate between Staphylococcus species from foods in Korea. This study provides valuable information that MALDI-TOF MS can be applied to monitor microbial populations and pathogenic bacteria in the food industry thereby contributing to food safety.

LULUCF 부문 산림 온실가스 인벤토리 구축을 위한 Sampling과 Wall-to-Wall 방법론 비교 (Comparison of Sampling and Wall-to-Wall Methodologies for Reporting the GHG Inventory of the LULUCF Sector in Korea)

  • 박은빈;송철호;함보영;김지원;이종열;최솔이;이우균
    • 한국기후변화학회지
    • /
    • 제9권4호
    • /
    • pp.385-398
    • /
    • 2018
  • Although the importance of developing reliable and systematic GHG inventory has increased, the GIS/RS-based national scale LULUCF (Land Use, Land-Use Change and Forestry) sector analysis is insufficient in the context of the Paris Agreement. In this study, the change in $CO_2$ storage of forest land due to land use change is estimated using two GIS/RS methodologies, Sampling and Wall-to-Wall methods, from 2000 to 2010. Particularly, various imagery with sampling data and land cover maps are used for Sampling and Wall-to-Wall methods, respectively. This land use matrix of these methodologies and the national cadastral statistics are classified by six land-use categories (Forest land, Cropland, Grassland, Wetlands, Settlements, and Other land). The difference of area between the result of Sampling methods and the cadastral statistics decreases as the sample plot distance decreases. However, the difference is not significant under a 2 km sample plot. In the 2000s, the Wall-to-Wall method showed similar results to sampling under a 2 km distance except for the Settlement category. With the Wall-to-Wall method, $CO_2$ storage is higher than that of the Sampling method. Accordingly, the Wall-to-Wall method would be more advantageous than the Sampling method in the presence of sufficient spatial data for GHG inventory assessment. These results can contribute to establish an annual report system of national greenhouse gas inventory in the LULUCF sector.

TiFe금속간 화합물의 Zr과 Ce첨가와 냉각속도에 따른 응고 조직 변화 및 기계적 특성 (Microstructure and Mechanical Property of TiFe Compounds with Zr or Ce Prepared at Different Solidification Rates)

  • 노혜인;최창완;이승훈
    • 한국주조공학회지
    • /
    • 제39권2호
    • /
    • pp.21-25
    • /
    • 2019
  • Microstructural and corresponding hardness changes of TiFe compounds with Zr (0~6 at%) or Ce (0~3 at%) were studied using samples prepared at different solidification rates. In arc-melted (TiFe)-Zr samples, the $Fe_{23}$ $Zr_6$ and $(Ti,\;Zr)_2Fe$ phases formed in the TiFe matrix, while in the (TiFe)-Ce sample, the $CeO_2$ phase formed along the grain boundary of the TiFe matrix. As the Zr content was increased, the volume fractions of the $Fe_{23}$ $Zr_6$ and $(Ti,\;Zr)_2Fe$ phases increased, forming a network structure. Accordingly, the hardness values of the samples also increased. With a small addition of Ce of approximately 0.1 at%, the as-cast microstructure could be effectively refined, reducing the average grain boundary diameter from ${\sim}100{\mu}m$ to ${\sim}14{\mu}m$. In the rapidly solidified sample prepared through a melt-spinning method, the constituent phases were identical to those of the arc-melted samples while the grains were refined. The microstructural changes of TiFe alloys can affect the hydrogen storage ability as well as the mobility of the hydrogen atoms in the alloys.

동결-해동 조건이 넙치육의 물리$\cdot$화학적 및 조직학적 변화에 미치는 영향 (Effects of Freezing-Thawing Conditions on Physicochemicnl and Histological Properties of Plaice, Paralichthys olivaceus Muscle)

  • 조영제;조민성;이남걸;최영준;김태진
    • 한국수산과학회지
    • /
    • 제31권4호
    • /
    • pp.463-470
    • /
    • 1998
  • 본 연구는 생선회 맛의 관능적 품질향상 및 생선회로서의 품질수명을 연장시키기 위하여 우리나라에서 고급횟감으로 널리 소비되고 있는 넙치를 시료로 하여 동결속도 및 해동방법에 따른 근육의 물리화학적 및 조직학적 변화를 살펴보았다. 1. 넙치를 chunk 형태로 급속동격 (액체질소동결) 및 완만동결 ($-15^{\circ}C$ 동결하였을때 최대 빙결정생성대의 통과시간은 각각 10분이내와 110분이었다. 해동방법에 다른 해동소요시간은 $25^{\circ}C$ 수도수. $15^{\circ}C$ 수도수 $10^{\circ}C$ 수도수. $25^{\circ}C$ 공기. $5^{\circ}C$ 수도수. $0^{\circ}C$ 수도수 순으로 짧았다. 2. 근육의 파괴강도는 급속동결하여 급속해동한 것이 완만동결하여 완만해동한 것에 비하여 높았으며. 조리형태에 따른 파괴강도는 급속동결한 것은 조리형태에 따라 큰 차이를 나타내지 않았으나, 완만동결한 것은 slice형태로 처리한 것이 높은 값을 나타내었다. 4. ATP의 잔존량은 동결속도에 큰 영향을 받지 않았으며, 급속해동한 것이 완만해동한 것에 비하여 높은 경향을 나타내었다. 그리고 IMP가 동결-해동후의 ATP관련화합물의 대부분을 차지하고 있었다. 5. 근육의 표본조직을 광학현미경 (LM)으로 관찰한 결과 즉살직후에는 근섬유간의 간격이 관찰되지 않았으며. 급속동결하여 해동방법을 달리한 근육에 있어서도 근섬유간의 간격이 거의 관찰되지 않았다. 그러나 완만동결하여 해동한 것은 근섬유간의 간격이 현저하게 관찰되었다.

  • PDF

환경시료의 방사능 분석에서 Monte Carlo 방법을 이용한 자체흡수 효과 보정 (Corrections of Self-Absorption Effect Using the Monte Carlo Method in the Radioactivity Analysis of Environmental Samples)

  • 서범경;이대원;이길용;윤윤일;양태건
    • Journal of Radiation Protection and Research
    • /
    • 제26권2호
    • /
    • pp.51-58
    • /
    • 2001
  • 환경방사능과 같은 저준위 방사능 측정에서는 원통형과 Marinelli형 측정용기가 가장 일반적으로 사용된다. 효율교정용 표준선원과 측정시료의 높이 또는 매질의 밀도가 다르면 자체흡수 효과의 차이로 인한 보정이 필요하다. 본 연구에서는 Monte Carlo 방법을 이용하여 HPGe 검출기의 전에너지 피크 효율을 계산하여 측정치와 비교하였다. 원통형 용기에 대해서는 높이에 대한 효율변화 정도를 계산하였고, 원통형 및 Marinelli 측정용기에 대해서는 밀도변화에 따른 효율을 계산하였다. 밀도에 따른 효율의 감소 정도는 1000keV 이하의 에너지 영역에 대해 자체흡수 효과의 보정치 필요하다는 것을 알았다. 또한 계산의 타당성을 검증하기 위하여 NIST SRM 4353 표준물질을 이용하여 계산값과 인증값을 상호비교한 결과 오차범위 이내로 잘 맞는 다는 것을 확인하였다.

  • PDF

FTIR과 XRD를 이용한 α-Quartz 분석법 비교 (Comparison of Analytical Methods for α-Quartz by FTIR and XRD)

  • 김부욱;이종성;최병순
    • 한국환경보건학회지
    • /
    • 제35권2호
    • /
    • pp.130-142
    • /
    • 2009
  • This study compared FTIR with XRD method for the analysis of quartz by % recovery, coefficient of variation (CV) and influence of the interference. the results were as the following. 1. In FTIR method, the coefficient of determination ($r^2$) was 0.9998 in a calibration curve of $695\;cm^{-1}$, and the limit of detection was $4.9{\mu}g/sample$. 2. The highest recovery was $799\;cm^{-1}$ (98.2%). 3. The CVpooled of the FTIR method was approximately 10% in three wave numbers. 4. The analysis of qualitative and quantitative for quartz is difficult with mixed cristobalite and iron oxide. 5. In XRD method with rotating sample holder and LynxEye detector, the coefficient of determination was 0.9996 in a calibration curve, and the limit of detection was $5.9{\mu}g/sample$. 6. The recovery and CV pooled were 104.3%, and 11 %, respectively. 7. In muffle furnace ashing, the quartz weight decreased to 34% when the maximum weight of the iron oxide was more than eight times. In conclusion, the accuracy (% recovery) and precision (CV) of FTIR and XRD method for analyzing $\alpha$-quartz were similar. FTIR method was a disadvantage for sample matrix because it indicates possibility of interference. However, XRD method distinguished specific crystalline forms of silica, and the majority of silicate minerals. In addition, XRD method recommend filter dissolution to pretreatment method.

Crown Ether/Chloroform 용매추출법을 이용한 토양시료중의 $^{89}Sr,\;^{90}Sr$ 분석 (Analysis of $^{89}Sr,\;^{90}Sr$ in Soil Sample Using Crown Ether/Chloroform Solvent Extraction Method)

  • 홍광희;최용호;김상복;이명호;박효국;최근식;김삼랑;이창우
    • Journal of Radiation Protection and Research
    • /
    • 제21권1호
    • /
    • pp.9-16
    • /
    • 1996
  • 환경시료 중 토양에 대한 방사성 스트론튬인 $^{89}Sr$$^{90}Sr$의 분석을 위해 Ca과 Sr을 분리하기 위한 방법으로 Crown ether를 이용한 추출방법을 사용하여 기존의 발연질산법과 비교하여 보았다. Crown ether를 이용한 추출방법을 기존의 발연질산법과 비교하여 보았을 때 높은 Sr 수율을 보였을 뿐만 아니라 분석에 소요되는 시간과 절차가 훨씬 빠르고 간단했다. Crown ether을 이용한 추출방법으로 원전주변 토양에 대한 방사성 스트론튬의 분석을 수행하였으며, 방사성핵종 분석에 의한 환경감시의 효율적인 수행을 위한 스트른튬 분석법을 제시하였다

  • PDF

Determination of Non-Steroidal Anti-Inflammatory Drugs in Human Urine Sample using HPLC/UV and Three Phase Hollow Fiber-Liquid Phase Microextraction (HF-LPME)

  • Cha, Yong Byoung;Myung, Seung-Woon
    • Bulletin of the Korean Chemical Society
    • /
    • 제34권11호
    • /
    • pp.3444-3450
    • /
    • 2013
  • Three phase hollow fiber-liquid phase microextraction (HF-LPME), which is faster, simpler and uses a more environmentally friendly sample-preparation technique, was developed for the analysis of Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) in human urine. For the effective simultaneous extraction/concentration of NSAIDs by three phase HF-LPME, parameters (such as extraction organic solvent, pH of donor/acceptor phase, stirring speed, salting-out effect, sample temperature, and extraction time) which influence the extraction efficiency were optimized. NSAIDs were extracted and concentrated from 4 mL of aqueous solution at pH 3 (donor phase) into dihexyl ether immobilized in the wall pores of a porous hollow fiber, and then extracted into the acceptor phase at pH 13 located in the lumen of the hollow fiber. After the extraction, 5 ${\mu}L$ of the acceptor phase was directly injected into the HPLC/UV system. Simultaneous chromatographic separation of seven NSAIDs was achieved on an Eclipse XDB-C18 (4.6 mm i.d. ${\times}$ 150 mm length, 5 ${\mu}m$ particle size) column using isocratic elution with 0.1% formic acid and methanol (30:70) at a HPLC-UV/Vis system. Under optimized conditions (extraction solvent, dihexyl ether; $pH_{donor}$, 3; $pH_{acceptor}$, 13; stirring speed, 1500 rpm; NaCl salt, 10%; sample temperature, $60^{\circ}C$; and extraction time, 45 min), enrichment factors (EF) were between 59 and 260. The limit of detection (LOD) and limit of quantitation (LOQ) in the spiked urine matrix were in the concentration range of 5-15 ng/mL and 15-45 ng/mL, respectively. The relative recovery and precision obtained were between 58 and 136% and below 15.7% RSD, respectively. The calibration curve was linear within the range of 0.015-0.96 ng/mL with the square of the correlation coefficient being more than 0.997. The established method can be used to analyse of NSAIDs of low concentration (ng/mL) in urine.