• Title/Summary/Keyword: Sam-Jo

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Induction of Apoptosis and Single Strand Breaks by Extract of Pulsatilla Koreana (SB-31).

  • Kim, Sam-Yong;Kim, Hyun-Soo;Park, Sang-Jun;Kim, Jong-Suk;Park, Jee-Young;Yoon, Whan-Joong;Yoon, So-Hyun;Jo, Deog-Yeon
    • Proceedings of the Korean Society of Applied Pharmacology
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    • 1996.04a
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    • pp.174-174
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    • 1996
  • Extract of Pulsatilla Koreana (SB-31) showed promising antitumor activity in vitro (J. Kor Cancer Asso 26:959-963, 1994). We studied the mechanism of cytotoxicity of SB-31. HL-60 cells were cocultivated with various concentrations of SB-31 for 5 hours. The DNAs from HL-60 cells exposed to SB-31 showed the ladder pattern typical of apoptosis. Effect of SB-31 on topoisomerase I activity was determined by slight modification of the method by E. Aflalo(1994). The pBR322 DNA showed dose-dependent increase of R-Form DNA upon incubation with SB-31. The topoisomerase Ⅰ-like activity (Increase of R-Form DNA) was accentuated with higher dose of SB-31. It is postulated that SB-31, which is a fermentation product of Pulsatilla koreana and which loses its activity when kept in ambient temperature for more than 96 hours, may contain topoisomerase Ⅰ-like activity and the enhanced excessive single strand breaks induced by 55-31 may result in apoptosis.

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Intraneural Ganglion Cyst of the Peripheral Nerve: Two Cases Report (말초 신경에 발생한 신경 내 결절종: 2예 보고)

  • Kim, Tai-Seung;Jo, Young-Hoon;Paik, Seung-Sam;Kim, Sung-Jae
    • The Journal of the Korean bone and joint tumor society
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    • v.19 no.2
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    • pp.83-86
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    • 2013
  • Ganglion cysts that occurred within sheaths of peripheral nerves have been documented in literatures, but it is relatively rare condition. The peroneal nerve is the most common site of involvement. Other reported sites of involvement are the radial, ulnar, median, sciatic, tibial and posterior interosseous nerves. We report a case of the intraneual ganglion cyst within peroneal nerve and another case of the intraneural ganglion cyst within a medial plantar nerve that were successfully excised without neurologic complication.

An Integrated CAD System for Design of Extruder Screw (압출 스크류 설계를 위한 CAD 시스템 개발)

  • Yoon, Jun-Young;Hwang, Yong-Keun;Park, Joo-Sam;Ko, Tae-Jo;Park, Jung-Whan
    • Journal of the Korean Society for Precision Engineering
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    • v.19 no.8
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    • pp.100-107
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    • 2002
  • The extruder screw is a part for extruding material in a injection molding machine. The screw's geometrical shape can mathematically be described by a sweep surface which is constructed by sweeping a section curve composed of a few circular arcs, along a helical guide curve. In the paper we developed a dedicated CAD system which basically is parametric in a sense that the system initially takes several design parameters to construct the geometric elements including the final sweep surface of the screw as well as section & guiding curves, along with feasibility check of the input parameter values, without further user interaction. The system has been developed as a built-in module onto a commercial CAD system, which can further incorporate additional NC-out functions with ease.

The bibliographical study on Poong-On(風溫) (풍온(風溫)에 관(關)한 문헌적(文獻的) 고찰(考察))

  • Han, Jae-Soo;Oh, Tae-Hwan;Jung, Sung-Gi;Rhee, Hyung-Koo
    • The Journal of Internal Korean Medicine
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    • v.13 no.2
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    • pp.141-155
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    • 1992
  • This study has been carried out to investigate the cause symptom and treatment of Poong-On(風溫) by referring to 29 leteratures. The results were obtained as follows; 1. The factors causing Poong-On(風溫) is wind and heat. 2. The symptom of Poong-On(風溫) is as follows. fever, chilling, cough, sweating sign, chest discomfort, thirst, Doo Chang Wan Bi(頭脹脘痺), Yang Maeg Boo Hwal(陽脈浮滑), Eum Maeg Yoo Yak(陰脈濡弱), Seol Tae Baek Bak(舌苔白薄). 3. The treatment-method of Poong-On(風溫) is as follows. Sin Ryang Hae Pyo(辛凉解表), San Poong Han Ii Rae Pyo(散風寒以解表), Seol Yeol Hwa Eum(泄熱和陰), So Sul Ii Hae Pyo(疏泄以解表). 4. The treatment-herbs of Poong-On(風溫) is as follows, Eun Gyo San(銀翹散), Ma Haeng Gam Sug Tang(麻杏甘石湯), Jo Wee Sung Gi Tang(調胃承氣湯), An Goong Woo Hwang Hwan(安宮牛黃丸), Seo Gag Ji Hwang Tang(犀角地黃湯), Baek Ho Tang(白虎湯), Sa Sam Maeg Moon Dong Tang(沙蔘麥門冬湯), Ga Gam Bok Maeg Tang(加減伏脈湯), Saeng Maeg San(生脈散).

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An Effective Buffer Management Scheme for Sequential and Looping References (순차 참조와 순환 참조들을 고려한 버퍼 캐쉬 관리 기법)

  • Kim, Jong-Min;Choe, Jong-Mu;Kim, Je-Seong;Lee, Dong-Hui;No, Sam-Hyeok;Min, Sang-Ryeol;Jo, Yu-Geun;Kim, Jong-Sang
    • Journal of KIISE:Computer Systems and Theory
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    • v.28 no.1_2
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    • pp.33-44
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    • 2001
  • 최근 버퍼 캐쉬의 성능을 향상시키기 위한 많은 블록 교체 기법들이 제안되었으며 이 중에서 작업 집합 (working set) 변화에 잘 적응하고 구현이 용이한 Least Recently Used (LRU) 블록 교체 기법이 널리 사용되고 있다. 그러나 LRU 블록 교체 기법은 블록들이 규칙적인 참조 패턴을 보이면서 순차 참조되거나 순환 참조될 때 이 규칙성을 적절히 이용하지 못해 성능이 저하되는 문제점을 가진다. 본 논문에서는 다중 응용 트레이스를 이용하여 LRU 블록 교체 기법의 문제점을 관찰하고, 이 문제점을 해결하는 통합된 형태의 효율적인 버퍼 관리 (Unified Buffer Management, 이하 UBM) 기법을 제안한다. UBM 기법은 순차 참조 및 순환 참조를 자동 검출하여 분리된 공간에 저장하고 이들 참조에 적합한 블록 교체 기법으로 이 공간을 관리한다. 또한 순차 참조와 순환 참조를 위한 공간과 나머지 참조를 위한 공간의 비율을 최적으로 할당하기 위해 온라인에서 수집된 정보를 이용하여 계산된 단위 공간 증가당 예상 버퍼 적중 증가율을 이용한다. 다중 응용 트레이스 기반 시뮬레이션 실험에서 UBM 기법의 버퍼 적중률은 LRU 블록 교체 기법에 비해 평균 12%, 최대 28%까지 향상된 결과를 보였다.

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The Exploratory Study of College Students'Motivation for the College Facebook Based on Factor Analysis (대학 페이스북에 대한 재학생 이용동기의 탐색적 연구)

  • Jo, Sam Sup
    • The Journal of the Korea Contents Association
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    • v.18 no.10
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    • pp.111-120
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    • 2018
  • The rapid use of Facebook among colleges, the present study was to explore the motivations of college owned Facebook among college students. The factor analysis The factor analysis showed that the college students perceived that the intimacy, update of college information, sharing daily lives, use of time, seeking useful information are important motivations when they use college Facebook. The extracted factors such as emotional intimacy, information update and sharing daily lives also play significant variables to affect Facebook effectiveness such as "like" and "sharing others." The results suggest that Facebook managers need to use college Facebook as a social medium not by one way communication medium to the college students.

Squeeze Film Damping of Perforated Planar Microstructures (기판에 수직으로 진동하는 다공 평판 미소구조물의 공기감쇠)

  • Kim, Eung-Sam;Jo, Yeong-Ho;Kim, Mun-Eon
    • The Transactions of the Korean Institute of Electrical Engineers C
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    • v.49 no.1
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    • pp.64-69
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    • 2000
  • This paper investigates the equeeze film damping of a perforated planar micromechanical structure that oscillates in the normal direction to the substrate. Special focus has been places on the effect of holes and edges of the perforated planar microstructures on the squeeze film damping of oscillatory motions. Theoretical models and test structures of the squeeze film damping have been developed for the transversely oscillating perforated plates. A set of nine different test structures, having three different sized with three different numbers of perforations, has been fabricated and tested. The experimental Q-factors, measured from the fabricated test structures, are compared with the theoretical values, estimated from finite element analysis. It is found that the finite element analysis overestimates the Q-factors up to 150% of the experimental values. Major discrepancy comes from the inaccuracy of the zero pressure condition, placed by the finite element analysis along the perforated edges.

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The Clinical Study on Yangdorak Change with Idiopathic Facial Paralysis Patients (특발성안면신경마비환자의 양도락 변화에 대한 임상적 고찰)

  • Kim, Kyung-Ok;Yang, Jae-Chul;Mun, Kyung-Suk;Lee, Kyung-Yun;Jang, Jo-Ung
    • Journal of Acupuncture Research
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    • v.22 no.6
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    • pp.201-209
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    • 2005
  • Objectives : We investicated correlation between Yangdorak and Meridian at Idiopathic facial nerve paralysis patients. Methods : For Yangdorak examination, We made a comparison between 21 patients who were diagnosticated to Idiopathic facial nerve paralysis and 22 persons who were not. Results : 1. The stress showed the highest frequency in premonitory cause at onset. 2. In comparing results on the Yangdorak general mean, they were not statistically significant between two group(p<0.05). 3. In comparing results on the Stomach(ST)-meridian Yangdorak mean, Idiopathic facial nerve paralysis group is stastically significant in comparison with non-facial paralysis group(p<0.05). 4. In comparing results on the Small Intestine(SI)-meridian Yangdorak mean, Idiopathic facial nerve paralysis group is not stastically significant in comparison with non-facial paralysis group(p<0.05). Conclusion : Yangdorak may be used for a method to objective clinical examination. But further studies are required for a use of practical indicator.

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Case History: Micropiling for Existing Foundation Retrofits (마이크로파일을 이용한 기초보강공법의 국내 적용 사례)

  • Lee, Jung-Hoon;Choi, Chang-Ho;Cho, Sam-Deok;Lee, Ki-Hwan;Jo, Hyun
    • Proceedings of the Korean Geotechical Society Conference
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    • 2008.03a
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    • pp.359-365
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    • 2008
  • As housing supply ratio has become over 100%, the strategic vision of government's policies has been changed from new construction to maintenance and regeneration of old architectural-structures. This fact has brought a light on the reconstruction and remodeling industries and a need for retrofit and rehabilitation techniques of existing foundation. Various methods of foundation for architectural-structures do exist. Among them, micropiling technologies are increasingly applied in foundation rehabilitation and seismic retrofitting projects. Micropiling techniques provide environmental-friendly methods for minimizing disturbance to adjacent structures, ground, and the environment. The installation is possible in restrictive area and general ground conditions. The fact that the installation procedures cause minimal vibration and noise and require very low ceiling height makes the micropiling methods to be commonly used for underpin existing structures. Specialized drilling equipment is often required to install the micropiles for existing basement facilities. This paper presents a case study in which micropiles were constructed to support a superstructure for vertical extension of existing elevator core and provide accessibility to underground parking lot. It is intended to become useful reference for the similar remodeling project.

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남해안의 해수 및 해저퇴적물 용출액과 적조생물 성장과의 관계 연구

  • Lee, Sam-Geun;Lee, Yeong-Sik;Im, Wol-Ae;Jo, Eun-Seop
    • Proceedings of the Korean Environmental Sciences Society Conference
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    • 2007.05a
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    • pp.447-449
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    • 2007
  • 유해성 적조생물인 C. polykrikoides에 대한 해역별 적조잠재력 평가를 위하여 유해성 적조가 자주 발생하는 남해안의 소리도 부근해역, 광양만, 남해도 주변해역, 거제만, 부산연안의 해수 및 해저퇴적물을 채집하여 배양실험을 실시하였다. 실험을 위한 기본배지는 f/2배지에서 배양조건은 온도 $20^{\circ}C$, 염분 34, 조도 2000Lux, 그리고 실험생물은 대수증식기의 C. polykrikoides를 $300cells/m{\ell}$접종하였다. 해역별 해수에 대한 적조생물 성장은 광양만에서 가장 높아 적조발생 잠재력이 가장 높았고, 다음은 부산 기장, 거제, 남해연안 순서로 성장이 높게 나타났으며, 질산성 질소 농도는 $0.35{\sim}24.74{\mu}M$ 범위로 적조생물의 성장과 같은 순서를 나타내었다. 한편 해저 퇴적물 용출액은 적조생물의 성장을 현저히 촉진시켰으며, 남해도 미조연안의 해저 퇴적물 용출액에서 적조발생 잠재력이 가장 높았고, 부산 형제도연안, 광양만, 거제만, 소리도연안의 해저퇴적물 순서로 적조생물의 성장을 촉진시키는 결과를 나타내었다. 그리고 적조생물의 성장은 인산염의 농도에 의해서 성장이 결정되었던 것으로 추정되며, 용출된 인산염의 농도 $1.59{\sim}10.39{\mu}M$ 범위로 남해 미조연안, 부산 형제도 연안, 광양만, 거제만, 소리도 연안 순서로 C. polykrikoides의 성장과 같은 순서로 나타났다.

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