• Title/Summary/Keyword: Salternamide E

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Salternamide E from a Saltern-derived Marine Actinomycete Streptomyces sp.

  • Kim, Seong-Hwan;Shin, Yoonho;Lee, Sang Kook;Shin, Jongheon;Oh, Dong-Chan
    • Natural Product Sciences
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    • v.21 no.4
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    • pp.273-277
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    • 2015
  • Comprehensive chemical analysis of extracts and fractions of marine actinomycete strains led to the discovery of a new minor secondary metabolite, salternamide E (1), from a saltern-derived halophilic Streptomyces strain. The planar structure of salternamide E (1) was elucidated by a combinational analysis of spectroscopic data including NMR, MS, UV, and IR. The absolute configuration of salternamide E (1) was determined by circular dichroism spectroscopic analysis. Salternamide E displayed weak cytotoxicity against various human carcinoma cell lines.