• Medical Lasers
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• 제10권3호
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• pp.161-169
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• 2021

Background and Objectives Fractional microneedle radiofrequency systems are popular options to increase elasticity in aging skin. Laser-assisted drug delivery is a promising method for the epidermal injection of topically applied drugs and cosmetic ingredients. This study assesses the safety and efficacy of topical delivery of L-ascorbic acid, vitamin E, and ferulic acid after fractional microneedle radiofrequency treatment for reducing photodamage. Materials and Methods In this prospective, single-center, split-face, controlled pilot study, six women (mean age, 48.0 years; range, 35-57 years; Fitzpatrick skin types III and IV) exhibiting mild to moderate photodamage, underwent a single session of fractional microneedle radiofrequency treatment. The patients were instructed to apply the antioxidant formulation to only one side of the face. Patients were evaluated 3 days, 7 days, and 4 weeks thereafter, using three-dimensional imaging and ultrasound. Ex vivo, the full-thickness human skin was used for molecular and histological evaluation. Statistical analysis was achieved by applying t-tests, Mann-Whitney U tests, and one-way analyses of variance. Results Compared to the untreated side, the antioxidant-treated side exhibited a significant increase in dermal thickness (10.32% vs. 17.54%, p < 0.05), but not in skin elasticity (4.76% vs. 4.69%, p > 0.05). The difference in erythema between the sides was statistically not significant (p > 0.05). In the ex vivo model, expression of FGF2 in the skin was significantly increased after application of the antioxidant formulation, as compared to results obtained subsequent to fractional microneedle radiofrequency treatment only (p < 0.01). Conclusion This study demonstrates that for the treatment of photodamaged skin, laser-assisted delivery of the antioxidant formulation is a safe and effective adjuvant modality following fractional microneedle radiofrequency.

• 분석과학
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• 제35권1호
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• pp.15-23
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• 2022

Food delivery is gaining popularity due to changes in lifestyle and dietary patterns. However, packages used to delivery food may contain contaminants including heavy metals, or additives added during manufacturing process which may migrate into food during processing and transportation. In this study, a total of 58 food packages for delivery were collected and tested for migration of heavy metals (lead, cadmium and arsenic), bisphenol A and phenol into food simulants. The method was validated by evaluating linearity of calibration curve, limit of detection, limit of quantification, recovery and precision. Result of heavy metal migration showed that lead was the most frequently migrated metal and the highest concentration was detected in a polypropylene sample. Although there are no specific migration limits for bisphenol A and phenol in packaging materials tested in this study, migrations of bisphenol A and phenol were detected in some packages. This may due to contamination or additives added during manufacture of packages. Risk (%) was calculated to analyze the risk associated with the migration of heavy metals, bisphenol A and phenol, and was always below 1 %. These results showed that food packages for delivery are safe in terms of heavy metals, bisphenol A and phenol migration.

• International Journal of Fuzzy Logic and Intelligent Systems
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• 제14권2호
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• pp.105-112
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• 2014

The International Maritime Organization has determined that more than 80% of maritime accidents are caused by human error. A variety of methods have been considered to reduce maritime accidents caused by such human error. Navigators operate by observing surrounding maritime situations and analyzing information using various navigational devices. This study proposes a system to ensure safe navigation by assisting navigators through the delivery of maritime safety information (MSI) between land and sea. In the future, supplementing the system through long-term on-the-ship tests is necessary by defining MSI in relation to maritime service portfolio regions.

• Asia pacific journal of information systems
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• 제13권4호
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• pp.97-118
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• 2003

The Internet provides a new way of doing business, but ease of copying and of sharing valuable digital information illegally across the Internet undermine many viable business models. This paper investigates the Digital Rights Management(DRM) as a means to provide safe protection and proper delivery of digital contents through the Information highway. First, we briefly summarize the current endeavor of DRM technical development and standardization process held in key technical working groups. Then, the paper provides a generic architecture for a DRM framework and shows the implementation of a prototype of DRM system incorporating key conceptual and technical standardization development. This study emphasizes the importance of developing the DRM architecture that provides the proper protection and safe transformation of digital contents in electronic commerce.

• 대한전자공학회:학술대회논문집
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• 대한전자공학회 2002년도 하계종합학술대회 논문집(3)
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• pp.51-54
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• 2002

P2P implies direct exchange between peers. If you have something I want, 1 go directly to you and obtain il. There is one of the most advantages of formation of community in P2P. For a specified purpose through P2P, the Peers who make temporary a group delivery a request efficient and safe. And the resources can be jointed common, cooperation and communication. When P2P is developed more, we can expect more formation of online community and development. But to be a safe of personal ID and password in internet, it should be possible to make a key-exchange. In the paper, it suggest P2P security system suitable to personal security that Kerberos be transformed. The user who make community in P2P, have Kerberos Server, and using Physical Address of Ethernet card in personal computer, authenticate users.

• 제어로봇시스템학회:학술대회논문집
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• 제어로봇시스템학회 2000년도 제15차 학술회의논문집
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• pp.406-406
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• 2000

In this study, as a part developing an unmanned container terminal (UCT), Ive designed and implemented an Autonomous Ground Vehicle (AGV) that can deliver containers in the port fast and safely as they are scheduled. It is preferable to research the intelligent UCT/AGV for delivering containers all day long without causing any trouble. For the sake of safe and fast AGV driving, we implemented a multiple-sensor system with vision, ultrasonic, and IR sensors and we adapted the hight-speed wireless LAN that satisfies the IEEE 802.11 Standard for hi-directional communication between the main processor in AGV and a host computer. The Pentium-III processor board mounted on the bottom frame in AGV combines and computes the information from sensors and controls the AGV driving. There are also the 80C196KC micro-controllers to control the actuating and steering motors. In addition, a steering function that is defined newly in this paper is heavily concerned in the mechanical design, and it plays an important role when AGV moves along a curve. Experimental results show the fast and safe delivery operations are possible with this UCT/AGV

• International Journal of Advanced Culture Technology
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• 제6권4호
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• pp.87-96
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• 2018

Meteorological information is essential for the safe operation of aircraft. Many organizations both at home and abroad provide meteorological services for small aircraft flying at a low altitude as a part of open public service and have performed relevant studies. Recently, such a service has been expanded to an online platform in order to deliver information more efficiently. The ultimate goal of this study is to improve the meteorological service for small low-altitude aircraft that mostly travel a short distance for a short time. To achieve this goal, this study considered requirements for developing an effective information delivery system and conducted a survey of user requirements to derive the necessary information that could be used to develop a real service.

• 한국항해학회지
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• 제20권3호
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• pp.13-30
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• 1996

It is general that large ships entering or leaving a port located in the East coast of Korean peninsular are often exposed athwart to swell while maneuvering in the vicinity of breakwater at harbor enterance or to prevailing wind inside the port in winter. Particulary, Many VLCCs laden with ore coal are calling at Pohang Port, on account of which it is likely that one of those VLCCs block the port if they were to run aground in fairway due to adverse circumstance of swell, prevailing winds or improper shiphandling. This accident may result in delay of delivery of raw material for Pohang Steel Mill which will bring about shortcomings of steel products for nationwide relevant industries causing national economic shock. Therefore, This study basically aims at establishment of certain criteria for safe unberthing of VLCC in this port to prevent such unexpected disaster because any VLLC is highly affected by external forces when in ballast condition. Computer simulations are unavoidable to fulfull this study successfuly and many simulations have been carried out repeatedly to find a model of safe unberthing under various unfavourable wind conditions. The "PC-based ship maneuvering simulator for training purpose" was used to perform numerous simulations at the least economic burden and to verify its availability that it can be used not only for training but also some other purposes. purposes.

• Archives of Plastic Surgery
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• 제46권3호
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• pp.189-197
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• 2019

There has been an exponential increase in plastic surgery cases over the last 20 years, surging from 2.8 million to 17.5 million cases per year. Seventy-two percent of these cases are being performed in the office-based or ambulatory setting. There are certain advantages to performing aesthetic procedures in the office, but several widely publicized fatalities and malpractice claims has put the spotlight on patient safety and the lack of uniform regulation of office-based practices. While 33 states currently have legislation for office-based surgery and anesthesia, 17 states have no mandate to report patient deaths or adverse outcomes. The literature on office-base surgery and anesthesia has demonstrated significant improvements in patient safety over the last 20 years. In the following review of the proceedings from the PRS Korea 2018 meeting, we discuss several key concepts regarding safe anesthesia for office-based cosmetic surgery. These include the safe delivery of oxygen, appropriate local anesthetic usage and the avoidance of local anesthetic toxicity, the implementation of Enhanced Recovery after Surgery protocols, multimodal analgesic techniques with less reliance on narcotic pain medications, the use of surgical safety checklists, and incorporating "the patient" into the surgical decision-making process through decision aids.

• 한국독성학회:학술대회논문집
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• 한국독성학회 2002년도 Current Trends in Toxicological Sciences
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• pp.133-133
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• 2002

Recently, there is an increasing nationwide concern in Korea that exposure to electric and magnetic fields (MF) in the home environment may not be safe in humans. We previously demonstrated that exposure of MF during the entire period of pregnancy did not induce any adverse effects on both pregnant dams and embryo-fetal development in rats.(omitted)