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Acupuncture for Prehypertension and Stage 1 Hypertension in Postmenopausal Women: A Randomized Controlled Pilot Trial (폐경 후 고혈압 전단계 및 1기 고혈압에 대한 침 치료 효과: 무작위 대조 예비연구)

  • Kim, Jung-Eun;Choi, Sun-Mi;Choi, Jin-Bong;Kim, Hyeong-Jun;Kwon, Ojin;Kim, Jae-Hong;Park, Ji-Eun
    • Korean Journal of Acupuncture
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    • v.34 no.3
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    • pp.116-125
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    • 2017
  • Objectives : The aim of this study was to assess the effectiveness of acupuncture in treating prehypertension and stage 1 hypertension in postmenopausal women. Methods : The study was a multi-center, four-arm, non-blinded, randomized clinical trial. Sixty participants were randomly assigned to experimental or control groups. The experimental groups received 10 acupuncture sessions over 4 weeks(Group A, n=20) or 20 sessions over 8 weeks(Group B, n=20) along with usual care. The acupoints were GB20, LI11, ST36, and SP6, bilaterally. The acupuncture groups were followed-up for an additional 12 weeks after acupuncture treatment. The control groups received usual care for 16 weeks(Group C, n=10) or 20 weeks(Group D, n=10). The outcomes were blood pressure, blood pressure control rates, lipid profile, and high-sensitivity C-reactive protein(hs-CRP). Results : After 4 weeks, DBP in the acupuncture groups(A+B) showed no significant decrease compared to the control group(C+D). However, after 8 weeks of acupuncture treatment, group B showed a significant decrease in DBP after acupuncture treatment and follow-up period compared to control group. Although there was no difference between the acupuncture and control groups in SBP after acupuncture treatment, group B showed a significant decrease in SBP compared to control group after follow-up period. Lipid profiles and hs-CRP did not differ significantly between acupuncture and control groups. Conclusions : Acupuncture treatment for 8 weeks showed the effect on prehypertension and mild hypertension. To verify the effect of acupuncture on blood pressure, rigorous trials including more participants are required.

Effect of Changes of Leaf Water Content on Respiration and Photosynthetic Rate of Tobacco Varieties (엽중수분 변화가 잎담배 품종간 호흡과 광합성속도에 미치는 영향)

  • Seong-Kook Bae;Ryuichi, Ishii;Atsuhiko, Kumura
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.30 no.4
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    • pp.347-351
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    • 1985
  • The effect of leaf water content on apparent photosynthesis and respiration of tobacco plants(five varieties) was studied under the condition without the irrigation for 10 days after the plants were sufficiently watered on the first day. The wild race (N. longiflora) among varieties showed highest apparent photosynthesis (AP) and AP had a positive correlation with specific leaf weight. N. longiflora and Andongyeob were different in their AP from the other varieties significantly under the water stress condition. Respiration rate also decreased to be simillar to AP except slight increase at early stage of water deficit. The stomatal resistance and the mesophyll resistance increased in the stressed plants. The water stress resistant character seems to be mainly due to open stomata.

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Statistical Characteristics and Stochastic Modeling of Water Quality Data at the Influent of Daejeon Wastewater Treatment Plant (대전시 공공하수처리시설 유입수 수질자료의 통계적 특성 및 추계학적 모의)

  • Pak, Gijung;Jung, Minjae;Lee, Hansaem;Kim, Deokwoo;Yoon, Jaeyong;Paik, Kyungrock
    • Journal of Korean Society on Water Environment
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    • v.28 no.1
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    • pp.38-49
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    • 2012
  • In this study, we analyze statistical characteristics of influent water quality in Daejeon waste water treatment plant and apply a stochastic model for data generation. In the analysis, the influent water quality data from year 2003 to 2008, except for year 2006, are used. Among water quality variables, we find strong correlations between BOD and T-N; T-N and T-P; BOD and T-P; $COD_{Mn}$ and T-P; and BOD and $COD_{Mn}$. We also find that different water quality variables follow different theoretical probability distribution functions, which also depends on whether the seasonal cycle is removed. Finally, we generate the influent water quality data using the multi-season 1st Markov model (Thomas-Fiering model). With model parameters calibrated for the period 2003~2005, the generated data for 2007~2008 are well compared with observed data showing good agreement in general. BOD and T-N are underestimated by the stochastic model. This is mainly due to the statistical difference in observed data itself between two periods of 2003~2005 and 2007~2008. Therefore, we expect the stochastic model can be applied with more confidence in the case that the data follows stationary pattern.

Are Blood Blister-Like Aneurysms a Specific Type of Dissection? A Comparative Study of Blood Blister-Like Aneurysms and Ruptured Mizutani Type 4 Vertebral Artery Dissections

  • Sim, Sook Young;Chung, Joonho;Shin, Yong Sam
    • Journal of Korean Neurosurgical Society
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    • v.56 no.5
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    • pp.395-399
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    • 2014
  • Objective : Blood blister-like aneurysms (BBAs) resemble arterial dissections. The purpose of this study was to investigate the relationship between these two disease entities and highlight commonalities and distinct features. Methods : Among 871 consecutive patients with aneurysmal subarachnoid hemorrhage, 11 BBAs of internal carotid artery and seven vertebral artery dissections (VADs) with a short segmental eccentric dilatation (Mizutani type 4), which is morphologically similar to a BBA, were selected. The following clinical factors were studied in each group : age, gender, risk factors, Hunt and Hess grade (HHG), Fisher grade (FG), vasospasms, hydrocephalus, perioperative rebleeding rate, and treatment outcome. Results : The mean age was 47.9 years in the BBAs group and 46.4 years in the type 4 VADs group. All the BBA patients were female, whereas there was a slight male predominance in the type 4 VAD group (male : female ratio of 4 : 3). In the BBA and type 4 VAD groups that underwent less aggressive treatment to save the parent artery, 29% (n=2/7) and 66.6% (n=2/3), respectively, eventually required retreatment. Perioperative rebleeding occurred in 72.7% (n=8) and 28.6% (n=2) of patients in the BBA and type 4 VAD groups, respectively. There was no statistical difference in the other clinical factors in both groups, except for the male dominancy in the type 4 VAD group (p=0.011). Conclusion : BBAs and ruptured type 4 VADs have a similar morphological appearance but there is a distinct clinical feature in gender and perioperative rebleeding rates. Complete isolation of an aneurysm from the parent artery might be the most important discipline for the treatment of these diseases.

Influence of the Optical Characteristics and Conductive Mechanism depending on the Deposition Condition of BCP (BCP의 증착 조건에 따른 광학적 특성 및 전도 기구에 미치는 영향)

  • Kim, Weon-Jong;Hong, Jin-Woong
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.22 no.11
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    • pp.980-986
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    • 2009
  • In a triple-layered structure of ITO/N,N'-diph enyl-N,N'bis(3-methylphenyl)-1,1' - biphenyl-4,4'-diamine(TPD)/tris(8-hydroxyquinoline)aluminum($Alq_3$)/(2,9-Dimethyl-4,7-diphenyl-1,10-phenanthroline(BCP)/Al device, we have studied the electrical and optical characteristics of organic light-emitting diodes(OLEDs) depending on the deposition condition of BCP layer. Several different sizes of holes on boat and several different deposition rates were employed in evaporating the organic materials. And then, electrical properties of the organic light-emitting diodes were measured and the performance of the devices was analyzed. It was found that the hole-size of crucible boat and the evaporation rate affect on the surface roughness of BCP layer as well as the performance of the device. When the hole-size of crucible boat and the deposition rate of BCP are 1.2 mm and $1.0\;{\AA}/s$, respectively, average surface roughness of BCP layer is lower and the efficiency of the device is higher than the ones made with other conditions. From the analysis of current density-luminance-voltage characteristics of a triple layered device, we divided the conductive mechanism by four region according to applied voltage. So we have obtained a coefficient of ${\beta}_{ST}$ in schottky region is $3.85{\times}10^{-24}$, a coefficient of ${\beta}_{PF}$ in Poole-Frenkel region is $7.35{\times}10^{-24}$, and a potential barrier of ${\phi}_{FN}$ in Fower-Nordheim region is 0.39 eV.

VOCs Removal in Drinking Water Treatment Process by Ozonation (오존산화에 의한 수처리공정에서 VOCs의 제거 특성)

  • Han, Myung-Ho;Choi, Joon-Ho;Lim, Hak-Sang
    • Journal of Korean Society of Water and Wastewater
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    • v.11 no.2
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    • pp.65-75
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    • 1997
  • Removal characteristics of volatile organic carbons(VOCs) by ozone oxidation and other processes in the raw water of the 1st Nakdong water treatment plant were investigated. Dichrolomethane, toluene and other 7 compounds were detected in the raw water. With regard to detected 4 compounds in finally treated water, it was found that VOCs could not be removed effectively by traditional water treatment process. Benzene, 1,2-dichlorobenzne were not detected in the raw water but they were detected in the process of treatment. The compound of highest detection frequency was dichloromethane. When the raw water was controlled at pH 7, temperature $20^{\circ}C$, 5 minutes as contact time, 10 minutes as reaction time, the removal rate of THMFP, $KMnO_4$ demand, TOC, $UV_{254nm}$ and $NH_3-N$ were 46.4%, 22%, 19.6%, 31% and 8%, respectively. From estimating the finally treated water qualities in 7 kinds of treatment processes, P-6 process(raw water-chlorination-coagulation-ozonation) was most effective for organics removal and THMs control. Removal efficiencies for $KMnO_4$ demand and TOC by the process which combined preozonation with coagulation was twice better than only preozonation. $NH_3-N$ removal rate was shown as 10% by P-3 process(raw water-coagulation-ozonation), but 83% of $NH_3-N$ was removed by P-4 process(raw water-coagulation-chlorination). It was found that the chlorination is more effective than the ozonation for the NH3-N removal as commonly known.

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Practice Preferences on Dabigatran and Rivaroxaban for Stroke Prevention in Patients with Non-valvular Atrial Fibrillation (비판막성 심방세동 환자의 뇌졸중 예방에서 dabigatran과 rivaroxaban의 임상적용의 현황)

  • Park, You Kyung;Kang, Ji Eun;Kim, Seong Joon;La, Hyen O;Rhie, Sandy Jeong
    • Korean Journal of Clinical Pharmacy
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    • v.26 no.3
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    • pp.207-212
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    • 2016
  • Objective: Prescription rate of dabigatran and rivaroxaban, which are the direct oral anticoagulants (DOAC), has increased. We have analyzed the prescription trend and medication use of dabigatran and rivaroxaban in patients with non-valvular atrial fibrillation (NVAF). Methods: It was retrospectively studied from September 2012 to April 2014 using the electronic medical records and the progress notes. Patients with NVAF (n=424) were evaluated on the medication use, prescribing preferences, adverse drug reactions (ADRs) and the availability of prescription reimbursement of dabigatran (n=210) and rivaroxaban (n=214). Results: Dabigatran was prescribed higher than rivaroxaban (23.3% versus 7.5%, p<0.001) in the neurology department, but rivaroxaban was prescribed higher compared to dabigatran in the cardiology department (87.4% versus 74.3%, p<0.001). Dabigatran was prescribed more than rivaroxaban in high risk patients with CHADS2 score ${\geq}3$ (44.3% versus 31.3%, p=0.006). Dabigatran patients seemed to have more ADRs than patients with rivaroxaban (25.2% versus 11.2%, p<0.001), but no serious thrombotic events and bleeding were found. Only 35.6% (n=151) were eligible for prescription reimbursement by the National Health Insurance (NHI). Bridging therapy (86, 31.5%) and direct-current cardioversion (57, 20.2%) were main reasons of ineligibility for reimbursement. Conclusion: Prescription preferences were present in choosing either dabigatran or rivaroxaban for patients with NVAF. Inpatient protocols and procedures considering patient-factors in NVAF need to be developed.

Two Cases of Stomach Cancer in Patients with Head and Neck Cancer (두경부암 환자에 병발된 위암 2예)

  • Kang Jin-Hyoung;Moon Chan-Soo;Kim Hoon-Kyo;Lee Kyung-Shik;Kim Dong-Jip;Yoon Sei-Chul;Cho Seung-Ho;Suh Byung-Do
    • Korean Journal of Head & Neck Oncology
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    • v.8 no.1
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    • pp.25-30
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    • 1992
  • The causes of treatment failure in head and neck cancer are locoregional recurrence, distant metastasis and second primary cancer. The favorite sites of second primary cancer are head and neck, lung and esophagus. But, the incidence of stomach cancer in Korea is the highest of all, high incidence of stomach cancer is expected in head and neck cancer patients. We experienced 2 cases of stomach cancer after successful treatment of primary head and neck cancer at Kang Nam St. Mary's hospital. The first case was a 60-year-old male with nasopharyngeal non-keratinizing carcinoma(stage III, T1N1M0). He received three cycles of induction chemotherapy including cisplatin and 5-fluorouracil followed by radiotherapy which resulted in complete response. Five months after completion of radiotherapy. stomach adenocarcinoma(stage IV, T4N2M1) was diagnosed. He received one cycle of FAM chemotherapy and died 4 months after diagnosis of stomach cancer. The second case was a 50-year-old male with pyriform sinus squamous cell carcinoma(stage II, T2N0M0). He received curative partial pharyngolaryngectomy followed by radiotherapy which result in free of disease. Four months after completion of radiotherapy. stomach adenocarcinoma(stage IV, T4N2M1) was diagnosed. Bypass gastrojejunostomy was performed. The screening test for stomach cancer including upper gastrointestinal X-xay series and/or endoscope of the stomach should be performed periodically for the patients with head and neck cancer in Korea.

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Effects of Nursing Education on Awareness of Risk Factors for Colorectal Cancer

  • Akduran, Funda;Cinar, Nursan
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.14
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    • pp.5763-5766
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    • 2015
  • Background: The objective of this study is to determine the effect of nursing education on awareness of risk factors for colorectal cancer. Materials and Methods: In this descriptive study, the sample is consisted of 132 volunteer students studying in the 1st and 4th grades of School of Health Nursing Department during the fall semester of 2014-2015. Data were collected via a questionnaire including information on the socio-demographic features of the participants and the correlating risk factors of colorectal cancer, prepared by researchers in view of the literature. The questionnaire was distributed to students and completed during class time. Before presenting the questionnaires to the respondents, informed consent was obtained from each. The data obtained were analyzed with a statistical package (SPSS). At first, a Kolmogorov-Smirnow test was performed on the research data. However, since it was seen that variables did not have a normal distribution, the Wilcoxon Signed Ranks Test was applied. P values of <0.05 were considered statistically significant. Percentages, means and standard deviations were also utilized for evaluation. Results: Of the total of 132 students participating in this study, 85.6% (n=113) were female, and 14.4% (n=19) were male. The average age was $20.5{\pm}2.04$. 54.5 % of the students (n=72) were 4th graders and 45.5 % (n=60) were first graders. Total score averages of first graders on risk awareness was $X=12{\pm}7.24$, and fourth graders was $X=16.93{\pm}7.71$. The difference between these two scores were found to be statistically significant (Z= -9,333; p=0.000). Conclusions: Nursing education was found out to have a positive influence on the students' awareness of risk factors for colorectal cancer.

The Seasonal Correlation Between Temperature and Precipitation Over Korea and Europe and the Future Change From RCP8.5 Scenario (우리나라 인근과 유럽의 계절에 따른 강수와 기온의 관계 및 RCP8.5 시나리오에 기반한 미래 전망)

  • Kim, Jin-Uk;Boo, Kyung-On;Shim, Sungbo;Kwon, Won-Tae;Byun, Young-Hwa
    • Atmosphere
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    • v.27 no.1
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    • pp.79-91
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    • 2017
  • It is imperative to understand the characteristics of atmospheric circulation patterns under the climate system due to its impact on climatic factors. Thus this study focused on analyzing the impact of the atmospheric circulation on the relationship between precipitation and temperature regionally. Here we used monthly gridded observational data (i.e., CRU-TS3.2, NOAA-20CR V2c) and HadGEM2-AO climate model by RCP8.5, for the period of 1960~1999 and 2060~2099. The experiment results indicated that the negative relationship was presented over East Asia and Europe during summer. On the other hand, at around Korea (i.e. EA1: $31^{\circ}N{\sim}38^{\circ}N$, $126^{\circ}E{\sim}140^{\circ}E$) and Northwestern Europe (i.e. EU1: $48^{\circ}N{\sim}55^{\circ}N$, $0^{\circ}E{\sim}16^{\circ}E$) in winter, strong positive relationship dominate due to warm moist advection come from ocean related to intensity variation of the East Asian winter monsoon (EAWM) and North Atlantic Oscillation (NAO), respectively. It was found that values of positive relation in EA1 and EU1 at the end of the 21st century is regionally greater than at the end of 20th century during winter since magnitude of variation of the EAWM and NAO is projected to be greater in the future as result of simulation with RCP 8.5. Future summer, the negative correlations are weakened in EA1 region while strengthened in EU1 region. For better understanding of correlations with respect to RCP scenarios, a further study is required.