• Journal of Acupuncture Research
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• v.20 no.5
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• pp.133-150
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• 2003

Objective: Recently. many studies have showed the evidences of the effect of the Electro-acupuncture treatment through scientific. Methods : One of these methods is functional MRI. We performed electro-acupuncture on Zusanli(St36) and observed the change of brain activation using fMRI. Zusanli(St36) is located on the lateral side of the lower leg. 3 cun(寸) inferior to the Patella of the lower border. Theoretically and clinically. this point has been considered very important for gynecological disorders. spleen and stomach disorders. and psychological disorders. To see the effects of electro-acupuncture stimulation on Zusanli(St36). the experiment was carried out on twelve healthy volunteers. using the gradient echo sequence with the 3.0T whole-body fMRI system(ISOL). After the needle insertion on right Zusanli(St36). 2 Hz of electric stimulation was given for 30 seconds. repeated five times. with 30 seconds' intervals. The Image analysis including motion correction. talairach transformation, and smoothing was done with SPM99. Results ad conclusion : The electro-acupuncture stimulation on Zusanli(St36) activates Brodmann Area 6, 13, 2, 19, 21, 22, 39, 40, 38, 3which indicates the pathways of the electro-acupuncture stimulation on Zusanli(St36) and the possibility of the relationship of the electro-acupuncture stimulation on Zusanli(St36) with autonomic nervous system, internal organic system.

• Korean Journal of Veterinary Research
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• v.40 no.2
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• pp.229-236
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• 2000

The synthesis of steroid hormone starts from cholesterol. Steroidogenic acute regulatory protein (StAR) acutely transfers cholesterol from the outer mitochondrial membrane to the inner in the early step of steroidogenesis. Many kinds of steroid hormone are mainly synthesized in adrenal grand, ovary, and testis. Among the steroid hormone, testosterone is synthesized in Leydig cells of the testis, the production of testosterone significantly increases in adult testis after puberty onset. Therefore, we think that the expression of StAR mRNA in testis will change according to the testicular development. The aim of this study is to determine the distribution of StAR mRNA in immature and adult rat testes and to confirm the functions of StAR in these testes. Thus, in situ hybridization was used in rat testes of the 2, 4, and 10 weeks of age. StAR mRNA was expressed in Leydig cells. Positive signals of StAR mRNA were weakly detected in Leydig cells of the 2 weeks of age. But, StAR mRNA was strongly expressed in Leydig cells of the 4 and 10 weeks of age, where steroidogenesis actively occur. In our results, the pattern of StAR mRNA expression was similar to the pattern of testosterone production in immature and adult rat testes. In conclusion, we can suggest that StAR acts as an important factor to regulate the synthesis of testosterone in Leydig cells of the rat testis.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.34 no.4
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• pp.348-354
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• 2001

This study was conducted to estimation of change characteristics for water quality by the dyke gate operation in the Keum River estuary. The estimation data made use of surveyed data in Keum River estuary by NERDI (National Fisheries Research and Development Institute) during $1990\~1999$. Shown to compare water quality changes at st. A and st. D in Figure 1, the concentrations of TSS, COD and nutrients at st. A were as high as about $2\~4$ times than those at st. D due to affection of fresh water discharge in the Keum River. The percentages of water quality change at surface water by dyke gate operation in the Keum River estuary were shown that TSS (Total Suspended Solid) was decrease to $56\%,\;47\%$ at st. A and D, and COD (Chemical Oxygen Demand) was increase to $68\%,\;71\%$ at st. A and D, respectively. The changes percentage of DIN (Dissolved Inorganic Nitrogen) by dyke gate operation in the Keum River estuary were increase high to $95\%$ at surface water and $7\sim30\%$ at bottom water, but those of DIP (Dissolved Inorganic Phosphorus) were increase to $2.8\sim8.6\%$ at surface water and $28\%$ at bottom water. The range of fluctuation for water quality at each station by dyke gate operation has shown that salinity and TSS are little better than before dyke gate operation, but COD show highly fluctuation. Also we studied estimation of characteristics of water quality change by the season, COD was increased except the summer, TSS was decreased to all season. DIN was increased to about $61\sim172.1\%$ for all season, but DIP was increased to the spring and decreased to the autumn, DIN enrichment in the estuary by dyke gate operation are interpreted to improvement of organic matter decomposition and nitrification by increasing the residence time and to increase nutrient flux in sediments due to decreasing dissolved oxygen and increasing a deposit matter.

• Journal of Institute of Control, Robotics and Systems
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• v.15 no.4
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• pp.406-412
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• 2009

ECG is used on purpose to keep good health or monitor cardiac function of aged person as well as on purpose to diagnose the disease of heart patients. The ambulatory ECG monitoring system under guarantee of safety and accuracy is very efficient to prevent the progress of heart disease and sudden death. These systems can detect the temporary change of ECG that is very significant to diagnose heart disease such as myocardial ischemia, arrhyamia and cardiac infarction. In this paper, we describe the ECG signal analysis algorithm and measurement device for ECG monitoring. The authors designed a small-size portable ECG device that consisted of instrumentation amplifier, micro-controller, filter and RF module. The device measures ECG with four electrodes on the body and detects QRS complex and ST level change in realtime. Also it transmits the measured signals to the personal computer. The developed software for ECG analysis in personal computer has the function to detect the feature points and ST level changes.

• The korean journal of orthodontics
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• v.16 no.1
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• pp.167-177
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• 1986

This study was undertaken to compare the main differences and its effects of the 4 first bicuspid extraction on the face and dental arch of the class II div 1 malocclusion. The subjects consisted of twenty two class II div 1 malocclusion, four males, eighteen females, were 14 Years 2 Months old at the stan of the treatment 16 Year 3 Months old at the end of the treatment. (mean age) Twenty one variables were observed by comparing the statistical data of the pretreatment records with postteratment records, which were consited of eight varibles on the study model digitation, thirteen variables on the tracing of the lateral cephalogram. The following results were obtained. 1. No significant change was observed in the intercanine width. 2. Intercuspal widths of the 1st. premolar and 2nd. premolar were decreased. 3. Change of the overjet was dependant upon upper anterior rather than lower anterior. 4. No significant changes were observed in facial plane angle and ANB angle. 5. Uprighting of the lower 1st. molar had an effect on the increase of the facial height.

• Journal of Acupuncture Research
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• v.24 no.6
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• pp.45-61
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• 2007

Objectives : The purpose of this study is to observe the effects of Carthami Flos herbal-acupuncture (CF-HA) at Joksamni($ST_{36}$) on arthritis in mice induced by Collagen II. Methods : The author performed several experimental items, including arthritis evaluation, change in weight, spleen size and stenosis rate, change in cytokine level, IgG, IgM and anti-collagen II, change of immunocyte count and histological change of the CIA mouse joint. Conclusions are as follows: Results : 1. In the CF-HA, the arthritis index and rate and the incidence of arthritis were decreased as the experiment proceeded. 2. In the CF-HA, spleen swell and stenosis, joint edema and change were decreased. 3. In the CF-HA, the level of $IL-1{\beta}$, IL-6, $TNF-{\alpha}$ and $IFN-{\gamma}$ in blood serum were significantly decreased. 4. In the CF-HA, the level of IgG, IgM and anti-collagen II were decreased. 5. In the CF- HA, $IFN-{\gamma}$, $IFN-{\gamma}/IL-4$, IL-10 of the culture fluid was decreased. 6. In the CF-HA, the cell rate of $CD3e^+$ and $CD45R^+$, $CD4^+$ and $CD8^+$, $CD4^+/CD25^+$ in spleen was similar to the cell rate of the normal group. 7. In the CF-HA, the cell rate of $CD4^+/CD25^+$, $CD45R^+/CD69^+$ in a lymph node was decreased as in the normal group. 8. In the CF-HA, the cell rate of $CD3^+/CD69^+$, $CD11b^+/Gr-1^+$ in joints was decreased as in the normal group. 9. In the CF-HA, the cartilage destruction and the inflammation cell growth in the H&E stain were decreased. The collagen fiber in the M&T stain were less destructed, therefore the result was similar to the normal group. Conclusions : These results suggest that CH-HA at $ST_{36}$ has an effect in controlling immune reaction and suppressing inflammation in rheumatoid arthritis therefore, the continuous flow of the following study is expected.

• Progress in Superconductivity
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• v.9 no.1
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• pp.35-39
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• 2007

Myocardial ischemia causes heterogeneity of ventricular repolarization and sometimes produces changes of the ST-T wave in ECG. Therefore, morphological changes of ST-T waveform in ECG have a clinical significance in diagnosing myocardial ischemia. In this study, we investigated the ST-T changes caused by myocardial ischemia in magnetocardiography (MCG). We analyzed MCG patterns of biphasic T, ST segment deviations from baseline, main current angle of $T_{peak}$ and $T_{peak}$ dispersion in 300 CAD patients without ST elevation in ECG, 122 symptomatic patients and 48 normal subjects. MCGs were recorded by multichannel SQUID system in a magnetically shielded room. As results, we found that appearances of the abnormality were strongly correlated with the severity of myocardial ischemia. Also we found that the percentage of the patients showing MCG changes were higher than those in ECG. These results show that morphological changes of ST-T waveform in MCG can be used as a marker of myocardial ischemia.

• 제어로봇시스템학회:학술대회논문집
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• 2002.10a
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• pp.77.3-77
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• 2002

In this paper, the algorithm for detecting the transient change of ST-segment and the device for measuring ECG from patient without restriction of activity are introduced. ST-segment elevation and depression is considered as the main characteristic in diagnosis of myocardial ischemia, but the change of pattern is also important. To consider all of the former and the latter, we used polynomial approximation for diagnosis of ECG. The feature points(R, S and T are detected through the signal processing processes including wavelet transform, and then R-S and S-T are approximated to polynomial. This method allows comparison of two signals that have different sampling time or different numbers of...

• Journal of Korean Medical Ki-Gong Academy
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• v.14 no.1
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• pp.52-62
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• 2014

Objective : The aim of this study is to analyze the effectiveness of Korean Medicine treatment on post-hysterectomy syndrome patients by thermographic change during treatment. Methods : 5 female patients who had a hysterectomy within a year were treated with Korean Medicine concluding acupuncture, herbal medicine, cupping therapy, herbal bath. We evaluated the thermographic differences by checking Digital Infrared Thermal Imaging(D.I.T.I.) at CV17(膻中), CV4(關元), ST3(巨髎), BL15(心兪), and BL23(腎兪). Results : In consequence of Korean Medicine Treatment for 3 weeks, thermographic differences between CV17(膻中) and CV4(關元), ST3(巨髎) and CV4(關元), BL15(心兪), and BL23(腎兪) tended to decrease. Conclusion : After Korean Medicine treatment, thermographic differences between upper body and lower body tended to decrease cause shangrexiahanzheng(上熱下寒證) made by hysterectomy became moderated.

• Proceedings of the Korea Committee for Ocean Resources and Engineering Conference
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• 2004.05a
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• pp.161-166
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• 2004

Research for deposits in Nakdong eatuary that research about Nakdong eatuary's sediment flows out in Nakdong-kang so far had been progressed but research about deposits that is flowed in open sea is insufficient. Observed Nakdong eatuary's characteristic of sediment transfer through observation during the second during Buteo 20 days on February 6, 2004 in this research Resuspension bed load Flux appeared high the first result St.4 point and St.5 point. St.4 branch had much bed load amount that is flowed in the east, and bed load that St.5 branch is flowed in the south appeared much Tendency such as the first showed in the second result, but compare with the first result and St.5 branch had much bed load that is transfer in end. Bed load that is transfer in observation result Nakdong river was less. As this, can know that amount of sediment that is transfer in open sea more than deposits that is transfer in Nakdong river is much Is expected to exert effect that deposits that is transfer in open sea is high in Nakdong estuary's topography change. Specially, observation result is expected that Nakdong estuary's deposition tendency becomes Jinwoodo southern and Shinho southern.