• 대한한방내과학회지
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• 제43권6호
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• pp.1134-1148
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• 2022

Purpose: We evaluated whether Spatholobus suberectus extract (SSE) can be used as a means of preventing and treating osteoporosis by measuring its effect on osteoclast differentiation, gene expression, and bone resorption. Methods: SSE was used to examine the effect on RAW 264.7 cells stimulated with RANKL to induce bone resorption. The inhibitory effect of TRAP formation and the expression of the bone resorption factors TRAP, cathepsin K, and MMP-9 during differentiation were measured. The effects on the differentiation-related factors NFATc and TRAIL and on the expression of OC-STAMP, DC-STAMP, ATP6v0d2, MITF, c-Fos, and inflammation-related factors were also evaluated. The effect on bone resorption was evaluated by culturing RANKL-treated osteoclasts on artificial bone fragments and observing the resulting resorption traces. The effect on bone damage in experimental animals was also measured. Results: SSE inhibited the differentiation of RANKL-stimulated osteoclasts into osteoclasts and suppressed the expression of cathepsin K, TRAP, MMP-9, NFATc1, TRAIL, MITF, OC-STAMP, DC-STAMP, ATP6v0d2, and c-Fos genes. Bone pore formation due to osteoclast action was also inhibited, and LPS-induced bone loss was suppressed in animal experiments. Conclusions: SSE could be useful for the prevention or treatment of osteoporosis by inhibiting osteoclast differentiation and bone resorption and suppressing bone loss induced in experimental animals. However, studies of larger populations are required.

• 제어로봇시스템학회:학술대회논문집
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• 제어로봇시스템학회 2004년도 ICCAS
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• pp.530-535
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• 2004

This paper considers a state set estimation (SSE) based model predictive control (MPC) for linear parameter- varying (LPV) systems with input constraint. We estimate, at each time instant, a feasible set of all states which are consistent with system model, measurements and a priori information, rather than the state itself. By combining a state-feedback MPC and an SSE, we design an SSE-based MPC algorithm that stabilizes the closed-loop system. The proposed algorithm is solved by semi-de�nite program involving linear matrix inequalities. A numerical example is included to illustrate the performance of the proposed algorithm.

• 한국마린엔지니어링학회:학술대회논문집
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• 한국마린엔지니어링학회 2005년도 후기학술대회논문집
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• pp.51-52
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• 2005

Optical characteristics of excitonic blue and green emission of Te-doped ZnSSe:Te epitaxial layers, grown by molecular beam epitaxy, were investigated by photoluminescence (PL) measurements. The Te-doped ternary specimen shows strong blue or green emission (at 300K) which is assigned to $Te_1$ or $Te_n$ $(n{\geq}2)$ cluster cluster bound exciton, respectively. Bright green and blue light emitting diodes (LEDs) have been developed using ZnSSe:Te system as an active layer. The green LEDs exhibit a fairly long device lifetime (>2000 h) when operated at 3 $A/cm^2$ under CW condition at room temperature.

• Journal of Advanced Marine Engineering and Technology
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• 제34권7호
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• pp.991-996
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• 2010

Blue-green and green LEDs have been successfully fabricated grown by MBE, which has introduced the $ZnS_ySe_{1-x-y}:Te_x$ (x=0.04, y~0.11-0.14) ternary epilayer as an active layer. From the I-V characteristics, the built-in voltage (~2.1 V) is very small compared to other wide bandgap LEDs, such as commercial InGaN-based LEDs (>3.2 V). From the C-V profiling, the effective carrier concentration in the p-type ZnMgSSe cladding layer was evaluated as ${\sim}2.8{\times}10^{16}\;cm^{-3}$ for the present LEDs.

• 한국소음진동공학회논문집
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• 제22권7호
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• pp.599-604
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• 2012

In this study, the safety of the driving gear reducer of ESW(essential service water) traveling sea water screen was evaluated through seismic analysis. Mode analysis of gear reducer was performed for reliability of analysis. Seismic analysis was performed in operating basis earthquake(OBE) and safe shutdown earthquake(SSE), which were applied as design condition using floor response spectrum( FRS). The maximum strain of gear reducer under OBE and SSE were 20.4 ${\mu}$ and 33.6 ${\mu}$, respectively. The maximum stresses were 2.42 MPa under OBE condition and 4.36 MPa under SSE condition, which were smaller than the allowable strength of material.

• 한국소음진동공학회:학술대회논문집
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• 한국소음진동공학회 2011년도 추계학술대회 논문집
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• pp.731-736
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• 2011

In this study, the safety of the driving gear reducer of ESW traveling sea water screen was evaluated through seismic analysis. Mode analysis of gear reducer was performed for reliability of analysis. Seismic analysis was performed in Operating Basis Earthquake(OBE) and Safe Shutdown Earthquake(SSE), which was applied as design condition using Floor Respnse Spectrum(FRS). The maxsimum displacement of gear reducer under OBE and SSE were 0.0137 mm and 0.0241 mm, respectively. The maximum stress of gear reducer under OBE and SSE were 2.42 MPa and 4.36 MPa, respectively.

• 한국전산구조공학회:학술대회논문집
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• 한국전산구조공학회 2011년도 정기 학술대회
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• pp.462-465
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• 2011

본 논문에서는 유한요소모델을 사용하여 원자력 발전용 해수 여과장치에 대한 동적 내진해석을 수행하였다. 장치의 검증을 위해서 운전기준지진(Operating Basis Earthquake, OBE)과 안전정지지진(Safe Shutdown Earthquake, SSE)이 설계하중으로 작용하였을 때 부재에 미치는 영향을 평가하였다. 해석대상은 유한요소법을 사용하여 수학적 모델링을 완성하였고, 층응답스펙트럼(Floor Response Spectrum, FRS)에 따른 지진하중과 사하중등을 적용하여 해석을 수행하였다. 해석된 해수여과장치의 최대변위는 OBE 조건에서 2.5 mm 이고, SSE 조건에서 최대변위는 4.6 mm 이다. 최대응력은 OBE 조건에서 24 MPa, SSE 조건에서 44 MPa이며, 이 값은 재료의 항복강도의 각각 18%, 27% 수준이다. 이에 따라 지진하중조건에 따른 해수여과장치의 구조적 안전성이 제시되었다.

• 대한가정학회지
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• 제29권4호
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• pp.131-150
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• 1991

The purpose of this study is to provide the basic data to measuring proper compensation for the homemakers. For this purpose, the value of household work is measured by variables and methods: overall substitute(OSE), specialised substitute (SSE), opportunity cost(OCE), reservation wage(RWE), subjective evaluation(SE). The Main Results are as follows: 1. The values by OSE, SSE, OCE, RWE and SE are respectively 497, 996, 676, 847, 616, 683, 707, 601 and 540, 366 won. 2. The values of homemakers are calculated individually by her demographic characteristics. 3, The values by SSE and OSE are increased in the order of type I.IV.III.II which are divided by the number of family member and age of homemaker.

• 한국원자력학회:학술대회논문집
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• 한국원자력학회 1997년도 춘계학술발표회논문집(2)
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• pp.477-482
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• 1997

Safe shutdown earthquakes (SSE) of four existing nuclear power plant sites were evaluated by using a probabilistic method. It turned out that the SSE's of the two sites are smaller than those of the rest. Site-specific response spectra were developed for two sites of which SSE's show a comparatively large difference. The result shows that the site-specific response spectrum of one site is higher by a factor of 1.5 than that of the other. The comparison of uniform hazard spectrum and site-specific response spectrum at one of the two sites shows that the both spectra are consistent with each other.

• Structural Engineering and Mechanics
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• 제86권3호
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• pp.311-324
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• 2023

Herein, we present effective polygonal finite elements to which the strain-smoothed element (SSE) method is applied. Recently, the SSE method has been developed for conventional triangular and quadrilateral finite elements; furthermore, it has been shown to improve the performance of finite elements. Polygonal elements enable various applications through flexible mesh handling; however, further development is still required to use them more effectively in engineering practice. In this study, piecewise linear shape functions are adopted, the SSE method is applied through the triangulation of polygonal elements, and a smoothed strain field is constructed within the element. The strain-smoothed polygonal elements pass basic tests and show improved convergence behaviors in various numerical problems.