• Journal of Institute of Control, Robotics and Systems
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• v.20 no.10
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• pp.1073-1078
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• 2014

In this paper, an effective repeat-back jamming (RBJ) mitigation scheme known assuccessive repeat-back jamming cancellation (SRC) is proposed for the utilization of the successive interference cancellation (SIC) algorithm which is used to mitigate the near-far effect and the multiple-access interference for code division multiple-access communication systems. The proposed scheme uses a combined pseudo-random noise (C-PRN) signal from the estimated major parameters of RBJ signals. To evaluate the performance of the proposed scheme, the root mean squared (RMS) code tracking errors are shown according to the standard deviation of the parameter estimation errors of an RBJ signal, and using the well-known major parameters estimation schemes with a C-PRN signal through Monte-Carlo simulation.

• Steel and Composite Structures
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• v.20 no.6
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• pp.1259-1274
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• 2016

A precast composite column system has been developed in this study by utilizing multi interlocking spiral steel into a centrifugally-formed hollow-core precast (CHPC) column. The proposed hybrid column system can have enhanced performances in the composite interaction behavior between the hollowed precast column and cast-in-place (CIP) core-filled concrete, the lap splice performance of bundled bars, and the confining effect of concrete. In the experimental program, reversed cyclic loading tests were conducted on a conventional reinforced concrete (RC) column fabricated monolithically, two CHPC columns filled with CIP concrete, and two steel-reinforced concrete (SRC) columns. It was confirmed that the interlocking spirals was very effective to enhance the structural performance of the CHPC column, and all the hollow-core precast column specimens tested in this study showed good seismic performances comparable to the monolithic control specimen.

• YAKHAK HOEJI
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• v.56 no.1
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• pp.26-34
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• 2012

Mast cells play an important role in early and late phase allergic reactions through allergen and IgE-dependent release of histamine, proteases, prostaglandins, and several multifunctional cytokines. In this study, we investigated whether Cudrania tricuspidata extract (CTE) suppresses IgE-mediated allergic responses in mast cells, an allergic animal model, and its mechanism of action in mast cells. We found that CTE inhibited IgE-mediated degranulation and cytokine production in rat basophilic leukemia (RBL)-2H3 mast cells and bone marrow-derived mast cells (BMMC), as well as passive cutaneous anaphylaxis (PCA) in mice. With regard to its mechanism of action, CTE suppressed the activating phosphorylation of spleen tyrosine kinase (Syk), a key enzyme in mast cell signaling processes and that of LAT, a downstream adaptor molecule of Syk in $Fc{\varepsilon}RI$-mediated signal pathways. CTE also suppressed the activating phosphorylation of mitogen-activated protein (MAP) kinases and Akt. The present results strongly suggest that the anti-allergic activity of CTE is mediated through inhibiting degranulation and allergic cytokine secretion by inhibition of Syk kinase in mast cells. Therefore, CTE may be useful for the treatment of allergic diseases.

• International Journal of Oral Biology
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• v.38 no.2
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• pp.67-72
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• 2013

This study examined the anti-osteoclastogenic effects of baicalin on receptor activator of NF-${\kappa}$B ligand (RANKL)-induced RAW264.7 cells. Baicalin is a flavonoid that is produced by Scutellaria baicalensis and is known to have multiple biological properties, including antibacterial, anti-inflammatory and analgesic effects. The effects of baicalin on osteoclasts were examined by measuring 1) cell viability; 2) the formation of tartrate-resistant acid phosphatase (TRAP) (+) multinucleated cells; 3) RANK/RANKL signaling pathways and 4) mRNA levels of osteoclast-associated genes. Baicalin inhibited the formation of RANKL-stimulated TRAP (+) multinucleated cells and also suppressed the RANKL-stimulated activation of p-38, ERK, cSrc and AKT signaling. Baicalin also inhibited the RANKL-stimulated degradation of $I{\kappa}B$ in RAW264.7 cells. In addition, the RANKL-stimulated induction of NFATc1 transcription factors was found to be abrogated by this flavonoid. Baicalin was further found to decrease the mRNA expression of osteoclast-associated genes, including carbonic anhydrase II, TRAP and cathepsin K in the RAW264.7 cells. Our data thus demonstrate that baicalin inhibits osteoclastogenesis by inhibiting the RANKL-induced activation of signaling molecules and transcription factors in osteoclast precursors.

• Steel and Composite Structures
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• v.20 no.3
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• pp.599-621
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• 2016

In order to study the working mechanism of rectangular steel-concrete composite columns subjected to compression-bending load and further determine the seismic performance index, a bottom strengthened rectangular steel reinforced concrete (SRC) column with concealed steel plates and a bottom strengthened rectangular concrete filled steel tube (CFST) columns were proposed. Six column models with different configurations were tested under horizontal low cyclic loading. Based on the experiments, the load-bearing capacity, stiffness and degradation process, ductility, hysteretic energy dissipation capacity, and failure characteristics of the models were analyzed. The load-bearing capacity calculation formulas for a normal section and an oblique section of bottom strengthened rectangular steel-concrete composite columns were pesented and a finite element (FE) numerical simulation of the classical specimens was performed. The study shows that the load-bearing capacity, ductility, and seismic energy dissipation capacity of the bottom strengthened rectangular steel-concrete composite columns are significantly improved compared to the conventional rectangular steel-concrete composite columns and the results obtained from the calculation and the FE numerical simulation are in good agreement with those from the experiments. The rectangular steel-concrete composite column with bottom strengthened shows better seismic behavior and higher energy dissipation capacity under suitable constructional requirements and it can be applied to the structure design of high-rise buildings.

• Korean Journal of Medicinal Crop Science
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• v.15 no.6
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• pp.451-456
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• 2007

Curcumin, a polyphenolic antioxidant purified from turmeric, has been known to possess various biological activities such as anti-oxidative, anti-inflammatory and anti-cancer effects. In this study, we have explored anti-inflammatory effect of curcumin using Gram (-) bacterium-derived endotoxin (lipopolysaccharide: LPS) and macrophage cell line RAW264.7. Curcumin suppressed NO production in LPS-activated RAW264.7 cells in a dose-dependent manner, Curcumin also blocked the activation of $NF-{\kappa}B$ but not AP-1 according to luciferase assay. Furthermore, this compound suppressed the phosphorylation of a series of intracellular signaling components such as Src, JAK-2, Akt, IKK and $I{\kappa}B{\alpha}$ under LPS stimulation in a time dependent manner, Therefore, our data suggest that curcumin was able to protect the host from Gram(-) bacterial-infection-mediated inflammatory symptoms.

• The Transactions of the Korean Institute of Power Electronics
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• v.19 no.1
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• pp.57-63
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• 2014

In this paper a bidirectional DC-DC converter is proposed for renewable energy systems, eco-friendly vehicles, energy storage systems, uninterruptible power supply(UPS) systems and battery test equipments. The two-stage bidirectional converter employing a fixed-frequency series loaded resonant converter is designed to be capable of operating under zero-current-switching turn on and turn off regardless of voltage and load variation, and hence its magnetic components and EMI filters can be optimized. And efficiencies and volumes of the two-stage bidirectional converters are compared according to configuration of isolated and non-isolated parts and a two-stage topology suitable for low voltage and high current applications is proposed. A 12kW(12V, 1000A) prototype of the proposed converter has been built and tested to verify the validity of the proposed operation.

• KIEAE Journal
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• v.7 no.6
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• pp.113-118
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• 2007

The composite beam adopted in the study was designed to reduce the floor height as well as to embed the top flange of steel frame into the slab that will enable to avoid applying the fire-resistant coating and to unify the joint method with a steel frame-type. As the steel frame and bottom concrete of the beam is pre-fabricated at the factory it could reduce the overall schedule at the jobsite. Applying such composite beam system to the work is expected to provide the efficient and enhanced performance, given the current tendency of the building construction that tends to be getting higher, larger and dense. The study focused on combining the composite beam with various column systems in a bid to propose the details thereof. A desirable composite girder can be adopted depending on site conditions through the evaluation of various beam and jointing approaches. Among the column systems applied to the study are steel column, SRC column, RC-PC column and RC column. The ways of combining with the columns addressed in the study were categorized into the rigid joint, pin joint, steel frame joint and bracket type joint. Besides, the instruction for site fabrication of beam-column was added in an effort to help set up the site fabrication procedures.

• Journal of Welding and Joining
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• v.2 no.2
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• pp.54-61
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• 1984

Construction of welding structure is greatly dependent upon welding heat cycle. Fracture toughness is decreased remarkablely due to coarse grained HAZ and inequal residual stress of three dimensions to originate in welding. Post weld heat treatment(PWHT) is carried out to increase the fracture toughness of HAZ and to remove the residual stress. There occur some problem such as toughness decrement and stress relief cracking(SRC) in the coarse grained HAZ subject to the effect of tempering treatment. Therefore, in this paper, the effect of heat inputs affecting cooling rate and PWHT under the no stress on fracture toughness were evaluated by crack opening displacement (COD), SEM and micro-hardness test. Experimental results are as follows; 1. Fracture toughness of weld HAZ is dependent upon weld heat cycle and it is decreased with increment of heat input, but the degree of improvement of fracture toughness after PWHT was linearly increased with heat input. 2. Hardness of the parent metal is not changed, but the softening of coarse grained HAZ is remarkable due to PWHT. 3. Fracture surface of as-weld show the perfect brittle fracture with the cleavage fracture, but after PWHT they appear the ductile fracture surface with dimple.

• Journal of The Geomorphological Association of Korea
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• v.23 no.2
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• pp.109-125
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• 2016

This study aims to identify the landslide susceptible zones of Boeun area and provide reliable landslide susceptibility maps by applying different modeling methods. Aerial photographs and field survey on the Boeun area identified landslide inventory map that consists of 388 landslide locations. A total ofseven landslide causative factors (elevation, slope angle, slope aspect, geology, soil, forest and land-use) were extracted from the database and then converted into raster. Landslide causative factors were provided to investigate about the spatial relationship between each factor and landslide occurrence by using fuzzy set and logistic regression model. Fuzzy membership value and logistic regression coefficient were employed to determine each factor's rating for landslide susceptibility mapping. Then, the landslide susceptibility maps were compared and validated by cross validation technique. In the cross validation process, 50% of observed landslides were selected randomly by Excel and two success rate curves (SRC) were generated for each landslide susceptibility map. The result demonstrates the 84.34% and 83.29% accuracy ratio for logistic regression model and fuzzy set model respectively. It means that both models were very reliable and reasonable methods for landslide susceptibility analysis.