• Title/Summary/Keyword: SOC

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Treatment Deintensification for Human Papillomavirus-Associated Oropharyngeal Cancer: Focused Review of Published Data (인유두종바이러스 연관 구인두암의 치료 약화 전략: 보고된 결과를 중심으로 분석)

  • Jin Ho, Kim
    • Korean Journal of Head & Neck Oncology
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    • v.38 no.2
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    • pp.7-13
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    • 2022
  • Human papillomavirus (HPV) is a causative agent for a subset of oropharyngeal cancer (OPC). The current standard of care (SOC) for locally advanced OPC is 70 Gy definitive radiotherapy (RT) concurrent with cisplatin, which entails significant proportions of acute and late grade 3 or higher toxicities. Accordingly, discovery of favorable prognosis of HPV-related OPC has led to enthusiasm to attenuate subspecialties therapy in multidisciplinary treatment. Diverse deintensification strategies were investigated in multiple phase 2 trials with an assumption that attenuated treatments result in comparable oncologic outcome and less toxicities compared with SOC. Several trials on chemotherapy deintensification revealed that concomitant administration of cisplatin is not to be omitted or substituted for cetuximab without compromising progression-free survival or local control. A transoral robotic surgery (TORS) is investigated as alternative local treatment, but TORS plus SOC or mild deintensified adjuvant RT showed similar toxicities and inferior oncologic outcomes compared with SOC definitive RT or moderately deintensified RT. However, it has been reported that TORS plus deintensified 30-36 Gy adjuvant RT results in excellent outcome and less late toxicity compared with SOC adjuvant RT. Several phase 2 trials reported apparently equivalent progression-free survival and local control and similar adverse effects with moderately deintensified 60 Gy RT compared with SOC 70 Gy RT. Further dose reduction below 60 Gy has been investigated using biology-directed approaches, which use response to induction chemotherapy or metabolic images to triage HPV-positive OPC for deintensified RT. In summary, these trials provide valuable insights for future directions. Available evidence consistently showed that moderately deintensified RT is effective and safe for HPV-positive OPC in both definitive and adjuvant settings. Concurrent cisplatin remains an essential component without which progression-free survival is significantly compromised for advanced HPV-positive OPC. A simple incorporation of TORS to SOC may be detrimental for oncologic outcome without anticipated toxicity reduction. Given the lack of level 1 evidence, it is prudent to curb an unjustified deviation from the current SOC and limit any deintensified strategies to clinical trials and adhere to the current SOC.

Effects of Successful aging and SOC coping strategies on the Quality of life of Middle-aged women (중년여성의 성공적 노화와 SOC 대처전략이 삶의 질에 미치는 영향)

  • Lee, Do-Young;Noh, Gie-Ok
    • The Journal of the Convergence on Culture Technology
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    • v.7 no.4
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    • pp.27-34
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    • 2021
  • This study is a descriptive research study to understand the effects of successful aging and SOC coping strategy on quality of life in middle-aged women. The study subjects were middle-aged women (40~65years old) across the country, and data were collected using a structured questionnaire. The collected data were analyzed by descriptive statistics, Independent t-test, one-way ANOVA, Pearson's correlation, and stepwise multiple regression using SPSS WIN/PC 24.0 statistics program. The study found that successful aging of middle-aged women, SOC alternative strategies and quality of life were statically correlated, and statistical significance was identified in order of successful aging(β=.41, p<.001) and SCO coping strategies(β=.17, p=.047) as variables describing quality of life. In this study, the explanatory power by the two variables was 24.7%. Therefore, in order to improve the quality of life of middle aged women, it is necessary to study and program programs to enhance the SOC coping strategy of successful aging.

Trends of SOC & SIEM Technology for Cybersecurity (Cybersecurity를 위한 SOC & SIEM 기술의 동향)

  • Cha, ByungRae;Choi, MyeongSoo;Kang, EunJu;Park, Sun;Kim, JongWon
    • Smart Media Journal
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    • v.6 no.4
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    • pp.41-49
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    • 2017
  • According to the occurrence of many security incidents, the SOC(Security Operation Center) and SIEM(Security Information & Event Management) are concentrated recently. The various studies and commercial products of the information security industry are being released. As reflected in this situation, NIST in the US is publishing and revising the document about the Cybersecurity Framework. In this study, we investigated the NIST's Cyberseurity Framework, trends in SOC and SIEM security technologies and solutions, and also introduce the open source Apache Metron of a real-time Bigdata security tool.

A Study on Battery SOC Estimation by Regenerative Braking in Electric Vehicles (전기자동차의 회생제동에 따른 배터리 SOC 추정방법에 대한 연구)

  • Zheng, Chun-Hua;Park, Yeong-Il;Lim, Won-Sik;Cha, Suk-Won
    • Transactions of the Korean Society of Automotive Engineers
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    • v.20 no.1
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    • pp.119-123
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    • 2012
  • In traditional vehicles, a great amount of energy is dissipated by braking. In electric vehicles (EVs), however, electric motors can be controlled to operate as generators to convert kinetic and potential energy of vehicles into electrical energy and store it in batteries. In this paper, the relationship between regenerative braking factor and battery final SOC is derived and the final SOC from the relationship is compared to that from simulation. Two types of braking algorithms are introduced and applied to an EV, and the final SOC derived from simulation is compared to that derived from the relationship.

The State of Charge Estimation for Lithium-Polymer Battery using a PI Observer (PI 상태관측기를 이용한 리튬폴리머 배터리 SOC 추정)

  • Lee, Junwon;Jo, Jongmin;Kim, Sungsoo;Cha, Hanju
    • The Transactions of the Korean Institute of Power Electronics
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    • v.20 no.2
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    • pp.175-181
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    • 2015
  • In this study, a lithium polymer battery (LiPB) is simply expressed by a primary RC equivalent model. The PI state observer is designed in Matlab/Simulink. The non-linear relationship with the OCV-SOC is represented to be linearized with 0.1 pu intervals by using battery parameters obtained by constant-current pulse discharge. A state equation is configured based on battery parameters. The state equation, which applied Peukert's law, can estimate SOC more accurately. SOC estimation capability was analyzed by utilizing reduced Federal Test Procedure (FTP-72) current profile and using a bi-directional DC-DC converter at temperature ($25^{\circ}C$). The PI state observer, which is designed in this study, indicated a SOC estimation error rate of ${\pm}2%$ in any of the initial SOC states. The PI state observer confirms a strong SOC estimation performance despite disturbances, such as modeling errors and noise.

Structural Equation Modeling on Successful Aging in Elders with Chronic Obstructive Pulmonary Disease Based on Selection-Optimization-Compensation Strategy (선택·적정화·보완(SOC) 이론에 근거한 만성폐쇄성폐질환을 가진 노인의 성공적 노화 구조모형)

  • Jang, Young Mi;Song, Rhayun
    • Journal of Korean Academy of Nursing
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    • v.47 no.4
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    • pp.488-498
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    • 2017
  • Purpose: The focus of the study was on the selection-optimization-compensation (SOC) strategy to predict successful aging mediated by dyspnea symptoms in older adults with chronic obstructive pulmonary disease. The model was constructed based on the hypotheses that coping strategy and social support of the elders predict successful aging through the SOC strategies. Methods: Participants were 218 outpatients with chronic obstructive pulmonary disease recruited for the study. Data collection was done from March 25 to September 11, 2015, and analyzed using SPSSWIN 22.0 and AMOS 21.0. Results: The hypothetical model appeared to be fit to the data. Seven of eight hypotheses selected for hypothetical model were statistically significant. The SOC strategy has only significant indirect effects through dyspnea symptoms on successful aging. Coping strategy, social support, SOC strategies and dyspnea symptoms explained 62% of variance in successful aging. Conclusion: The SOC strategies with social support and dyspnea symptoms significantly explained successful aging among patients with chronic obstructive pulmonary disease. Nursing strategies should be focused on social support and coping strategies to optimize SOC strategies so that older adults with chronic obstructive pulmonary disease are able to manage dyspnea symptoms and eventually achieve successful aging.

State-of-charge Estimation for Lithium-ion Batteries Using a Multi-state Closed-loop Observer

  • Zhao, Yulan;Yun, Haitao;Liu, Shude;Jiao, Huirong;Wang, Chengzhen
    • Journal of Power Electronics
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    • v.14 no.5
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    • pp.1038-1046
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    • 2014
  • Lithium-ion batteries are widely used in hybrid and pure electric vehicles. State-of-charge (SOC) estimation is a fundamental issue in vehicle power train control and battery management systems. This study proposes a novel model-based SOC estimation method that applies closed-loop state observer theory and a comprehensive battery model. The state-space model of lithium-ion battery is developed based on a three-order resistor-capacitor equivalent circuit model. The least square algorithm is used to identify model parameters. A multi-state closed-loop state observer is designed to predict the open-circuit voltage (OCV) of a battery based on the battery state-space model. Battery SOC can then be estimated based on the corresponding relationship between battery OCV and SOC. Finally, practical driving tests that use two types of typical driving cycle are performed to verify the proposed SOC estimation method. Test results prove that the proposed estimation method is reasonably accurate and exhibits accuracy in estimating SOC within 2% under different driving cycles.

Location Suitability Assessment of the Living SOC Project in Rural Areas - Focusing on the Sports Center - (농촌 생활SOC 사업의 입지 적합성 평가 - 국민체육센터를 중심으로 -)

  • Kim, Hyun-Joong;Lim, Sang-Yon;Seong, Eun-Young
    • Journal of Agricultural Extension & Community Development
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    • v.29 no.3
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    • pp.173-189
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    • 2022
  • This study aims to evaluate the location suitability of the Living SOC Project in rural areas. For the assessment of location suitability, we applied location efficiency and location equity, respectively. One hundred sixteen national sports centers in 57 rural areas are selected as the target of analysis. The location efficiency and location equity in each sports center revealed a large gap between facilities. The location suitability evaluation results examined in 57 rural areas were similar to those analyzed at individual facilities. The correlation between the location suitability results and rural characteristics was weak. Also, location efficiency and location equity have a fragile relationship. In the light of these results, the location of the sports center, whose supply has been confirmed in rural areas through the Living SOC project, does not consider regional characteristics actively. In addition, it is difficult to say that the location efficiency and location equity of sports centers have been proactively estimated. Therefore, breaking away from the performance-oriented policy and switching to a lifestyle SOC supply policy based on the pre- and ex-post location evaluation system is necessary.