• Molecules and Cells
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• v.41 no.9
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• pp.842-852
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• 2018

Notch signaling is an evolutionarily conserved pathway and involves in the regulation of various cellular and developmental processes. Ligand binding releases the intracellular domain of Notch receptor (NICD), which interacts with DNA-bound CSL [CBF1/Su(H)/Lag-1] to activate transcription of target genes. In the absence of NICD binding, CSL down-regulates target gene expression through the recruitment of various corepressor proteins including SMRT/NCoR (silencing mediator of retinoid and thyroid receptors/nuclear receptor corepressor), SHARP (SMRT/HDAC1-associated repressor protein), and KyoT2. Structural and functional studies revealed the molecular basis of these interactions, in which NICD coactivator and corepressor proteins competitively bind to ${\beta}-trefoil$ domain (BTD) of CSL using a conserved ${\varphi}W{\varphi}P$ motif (${\varphi}$ denotes any hydrophobic residues). To date, there are conflicting ideas regarding the molecular mechanism of SMRT-mediated repression of CSL as to whether CSL-SMRT interaction is direct or indirect (via the bridge factor SHARP). To solve this issue, we mapped the CSL-binding region of SMRT and employed a 'one- plus two-hybrid system' to obtain CSL interaction-defective mutants for this region. We identified the CSL-interaction module of SMRT (CIMS; amino acid 1816-1846) as the molecular determinant of its direct interaction with CSL. Notably, CIMS contains a canonical ${\varphi}W{\varphi}P$ sequence (APIWRP, amino acids 1832-1837) and directly interacts with CSL-BTD in a mode similar to other BTD-binding corepressors. Finally, we showed that CSL-interaction motif, rather than SHARP-interaction motif, of SMRT is involved in transcriptional repression of NICD in a cell-based assay. These results strongly suggest that SMRT participates in CSL-mediated repression via direct binding to CSL.

• Journal of the Korean Operations Research and Management Science Society
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• v.1 no.1
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• pp.111-125
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• 1976

This study investigates the one-year performance of the Seoul Metropolitan Rail Transit(SMRT) operation. It intends to provide a basic understanding for railway operation in Seoul Metropolitan Area and thereby for making rational transport policy. The paper is conceptually comprised of four sections; analysis of passenger travel characteristics; SMRT costing and traffic cost function: its operating characteristics in terms of finance and utilization; primary social benefits of SMRT and suggestions. In the first year of operation (1974), the average daily traffic was about 335,000, After the drastic increases of fare in both Subway and KNR rail-lines, the travel volume has been cut by almost 10 percent, though most pronounced on intra-Subway line. The spatial distribution of passengers indicates that travelers use the SMRT line mainly for uninterrupted direct travel toward the CBD. In the prospective costing, the opereting expenses are divided into three groups; those which vary directly with volume; those partially variable with volume; and those entirely unrelated to volume change, With this information, cost function was derived for varying schedules of operation. Primary social benefits of the SMRT are assessed, though preliminary. Account should be taken of the nature of common costs of the SMRT in fare-rate making, especially when much of the operating expenses are accounted for by the fixed costs such that the revenue may not readily turn into break-even. The accounting results of the one-year operation coincide reasonably well with the prospective costing estimates. According to the findings of this annd another travelers' behavior studies, managerial effort would bring more revenue gain to the SMRT than fare increase does, not to speak of greater social benefits by so doing.

• Proceedings of the KSR Conference
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• 2011.05a
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• pp.895-903
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• 2011

The Seoul Metropolitan Rapid Transit Corporation(SMRT) is studying the New Train Control System based on Wireless Communication(CBTC System : Communication Based Train Control System) to overcome the limitations of the existing system and to deal with the switch to the new system. The SMRT's New Train Control System Based on three main elements(train position detecting, radio communication and train control) is being developed in 3 stages. Currently, the development of the train position detecting element with the RFID system and the train position detecting device and the radio communication element with RTIS and DSRC had been developed and equipped on 3 stations(Songpa~Garak Market~Munjeong, 7.3km) of Subway Line 8 in the pilot. Such a basic infrastructure of the SMRT's New Train Control System is having an efficiency test by using the real-time Train Monitoring System and Currently, the third element, the train control(ATP/ATO/ATS/Interlocking) for the study is in progress. Also, the developed system is expected to validate the performance and safety in the next three stage. This paper shows about major developments of the SMRT's New Train Control System and our future plans.

• Proceedings of the KSR Conference
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• 2011.10a
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• pp.2573-2580
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• 2011

SMRT(Seoul Metropolitan Rapid Transit Corporation) changed PC-oriented office system to Smart-Phone oriented mobile office system(STnF: SMRT Talk & Flash), and provided smart phone to all staffs. STnF make it possible not only voice communication between staff, but also to input and inquiry all kind of information related to work(ex: Facility maintenance, Rolling Stock management, office management, Finance, human resource etc.) based on smart phone. STnF conquers the limitation of time and space. All staffs can commute to the site directly to reduce moving time and to share information between staffs, so SMRT improve speed and reliability of work by making a quick decision and action on the spot. After introduction of STnF, within 1 year, the equipment failure ratio fell to 47%. Mobile office system reduced and level-off the step of approval. so enhanced civil customer service. Quantification and scientific movement of work make it fast evolution and development. These business improvement make it possible to put more outstanding manpower on new business and R&D project, and this contributes to company's management effectiveness.

• Proceedings of the KSR Conference
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• 2011.10a
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• pp.737-747
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• 2011

5678SMRT has installed various sensor for operating conditions(field of electric, facilities, signal, communication equipment and track) and environment of Every Function Room for remotely detecting and monitoring. Installed sound sensor for analyzed after remotely heard the noise of every equipment at Every Function Room and temperature sensor for check the temperature condition of Every Function Room. Additional installed voltage sensor in signal equipment room for monitoring RF track-circuit's voltage condition. Installed displacement sensor at The Chungdam bridge's railway for measuring and monitoring track displacement caused by temperature change and Pan/Tilt camera at sub-station and drainage for remotely field monitoring. Installed sensor for each equipment's operating condition and failure at Every Function Room then periodic check of workforce turned to around-the-clock surveillance by sensor therefore improvement of operating equipment. SMRT is lots of prevent a failure by Immediately detect of precondition of equipment failure by analyzed the sensor data. If the occurrence of an failure, become detected Immediately so possibility correct diagnosis and order by remotely field check by installed camera and sound sensor at field.

• Proceedings of the KSR Conference
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• 2008.06a
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• pp.1407-1415
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• 2008

Recently, there has been growing interest in Gyongin Line demand estimation, because SMRT(Seoul Metropolitan Rapid Transit Corporation) Line 7 will be extended west by 9.8km from Onsu to meet the Gyongin Line at Bupyeong-gu Office. This study was designed to estimate the change of traffic demand in Gyongin Line before and after the completion year 2011, also provide against the economic loss caused by the derived demand from Gyongin Line to SMRT Line 7. In this paper we give preliminary results for the strategic plans for traffic demand estimation and train operating plan in Gyongin Line by analyzing transport performance of Seoul metropolitan subway, and an additional study on the transportation market and the urban development plan is needed for more accurate results.

• The Korean Journal of Archival Studies
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• no.11
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• pp.181-214
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• 2005

Metropolitan rapid transit system plays an essential role in the public transportation system of any large city, and its managing agency is usually charged with the responsibility of storing and managing the design drawings of the system. The drawings are important and historically valuable documents that must be kept permanently because they contain comprehensive data that is used to manage and maintain the system. However, no study has been performed in Korea on how well agencies are preserving and managing these records. Seoul Metropolitan Rapid Transit Corporation(SMRT) is the managing agency established by the city of Seoul to operate subway lines 5, 6, 7, and 8 more efficiently to serve its citizens. By the Act on Records Management in Public Institutions(ARMPI), SMRT should establish a records center to manage its records. Furthermore, all drawings produced by SMRT and other third party entities should be in compliance with the Act. However, SMRT, as a form of local public corporation, can establish a records center by its own way. Accordingly, the National Archives & Records Service(NARS) has very little control over SMRT. Therefore, the purpose of this study is to research and analyze the present state of storage and management of the drawings of metropolitan rapid transit in SMRT and is to find a desirable method of preservation and management for drawings of metropolitan rapid transit. In the process of the study, it was found that a records center is being considered to manage only general official documents and not to manage the drawings as required by ARMPI. SMRT does not have a records center, and the environment of management on the drawings is very poor. Although there is a plan to develop a new management system for the drawings, it will be non-compliant of ARMPI. What's happening at SMRT does not reflect the state of all other cities' metropolitan rapid transit records management systems, but the state of creation of records center of local public corporation is the almost same state as SMRT. There should be continuous education and many studies conducted in order to manage the drawings of metropolitan rapid transit efficiently by records management system. This study proposes a records center based on both professional records centers and union records centers. Although metropolitan rapid transit is constructed and managed by each local public corporation, the overall characteristics and processes of metropolitan rapid transit projects are similar in nature. In consideration of huge quantity, complexity and specialty of drawings produced and used during construction and operation of metropolitan rapid transit, and overlap of each local public corporation's effort and cost of the storage and management of the drawings, they need to be managed in a professional and united way. As an example of professional records center, there is the National Personnel Records Center(NPRC) in St. Louis, Missouri. NPRC is one of the National Archives and Records Administration's largest operations and a central repository of personnel-related records on former and present federal employees and the military. It provides extensive information to government agencies, military veterans, former federal employees, family members, as well as researchers and historians. As an example of union records center, there is the Chinese Union Dangansil. It was established by several institutions and organizations, so united management of records can be performed and human efforts and facilities can be saved. We should establish a professional and united records center which manages drawings of metropolitan rapid transit and provides service to researchers and the public as well as members of the related institutions. This study can be an impetus to improve interest on management of not only drawings of metropolitan rapid transit but also drawings of various public facilities.

• Information Systems Review
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• v.13 no.3
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• pp.99-121
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• 2011

With the advancement of mobile information technology, the era of smart work emerges as a means for enabling us to overcome temporal and spatial constraints. Thanks to smart mobile devices with seamless access, organizations can assign tasks to employees and provide services to the appropriate customers in mobile environments. In addition, smart work facilitates the improvement of coordination and collaboration among individuals and groups performing organizational tasks. The dramatic performance improvement is manifest by utilization of smart work in organizations. Therefore, the interest in the introduction of smart work is growing. With the lens of time-geography, this study investigates what makes smart work successful. This research, especially, concentrates on the processes for overcoming the temporal and spatial constraints in the field. A case study of the Seoul Metropolitan Rapid Transit Talk and Flash (SMRT T&F) is developed and analyzed through the framework of time-geography and the implementation processes and success factors of SMRT T&F are investigated.

• Journal of the Korean Society for Railway
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• v.15 no.4
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• pp.381-387
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• 2012

This paper is aimed to analyze the achievements of the Tunnel Monitoring System(TMS), implemented in Seoul subway L5~L8, and to find out improved methods. By introducing the TMS, it is possible to inspect tunnel facilities for 24 hours a day while trains are operated. The inspection capability could be expanded, the accuracy was improved, and the cycle was shortened. The efficiency of manpower was improved and the surplus manpower could be used for other tasks of facilities maintenance. As a result, by introduction of the TMS, the amount of tunnel maintenance was increased by 225% and the train service troubles caused by facility problems were decreased by 53%.

• Journal of the Korean Society for Railway
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• v.11 no.3
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• pp.240-247
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• 2008

Recently, railway corporations have built maintenance information systems and collected failure and maintenance data. For example Seoul Metropolitan Rapid Transit Corporation (SMRT) built the Electric Motor Unit-Information System (EMU-IS) which is the first maintenance information system in Korea. It has been operated from August, 2000. This paper deals with a case study on determining maintenance interval through reliability analysis using EMU-IS fault data. Door system is considered for the case study in which reliability is evaluated for operating time and distance and the overhaul interval is determined.