• Biomolecules & Therapeutics
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• v.26 no.3
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• pp.306-312
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• 2018

In a previous study, we have demonstrated that S-methylmethionine sulfonium (SMMS) confers wound-healing and photoprotective effects on the skin, suggesting that SMMS can be used as a cosmetic raw material. However, it has an unpleasant odor. Therefore, in the present study, we synthesized odor-free SMMS derivatives by eliminating dimethyl sulfide, which is the cause of the unpleasant odor and identified two derivatives that exhibited skin-protective effects: one derivative comprised (2S,4S)- and (2R,4S)-2-phenylthiazolidine-4-carboxylic acid and the other comprised (2S,4R)-, (2S,4S)-, (2R,4R)-, and (2R,4S)-2-phenyl-1,3-thiazinane-4-carboxylic acid. We performed in vitro proliferation assays using human dermal fibroblasts (hDFs) and an immortalized human keratinocyte cell line (HaCaT). The two SMMS derivatives were shown to increase hDF and HaCaT cell proliferation as well as improve their survival by protecting against ultraviolet exposure. Moreover, the derivatives regulated the expression of collagen type I and MMP mRNAs against ultraviolet exposure in hDFs, suggesting that these derivatives can be developed as cosmetic raw materials.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.21 no.8
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• pp.2077-2089
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• 1996

In this paper, a memory organization and its control method are proposed for the implementation of parallel Virterbi decoders. The design is mainly focused on lowering the hardware complexity of a parallel Viterbi decoder which is to reduce the decoding speed. The memories requeired in a Viterbi decoder are the SMM(State Metric Memory) and the TBM(Traceback Memory);the SMM for storing the path metrics of states and the TBM for storing the survial path information. A general parallel Viterbi decoder for high datarate usually consists of multiple ACS (Add-Compare-Select) units and their corresponding memeory modules.for parallel ACS units, SMMs and TBMs are partitioned into smaller independent pairs of memory modules which are separately interleaved to provide the maximum processing speed. In this design SMMs are controlled with addrss generators which can simultaneously compute addresses of the new path metrics. A bit shuffle technique is employed to provide a parallel access to the TBMs to store the survivor path informations from multiple ACS modules.

• Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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• v.26 no.1
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• pp.85-91
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• 2008

When a large sparse matrix is calculated for a horizontal geodetic network adjustment, it needs to go through the process of matrix reordering for the efficiency of time and space. In this study, several reordering methods for sparse matrix were tested, using Sparse Matrix Manipulation System(SMMS) program, total processing time and Fill-in number produced in factorization process were measured and compared. As a result, Minimum Degree(MD) and Mutiple Minimum Degree(MMD), which are based on Minimum Degree are better than Gibbs-Poole-Stockmeyer(GPS) and Reverse Cuthill-Mckee(RCM), which are based on Minimum Bandwidth. However, the method of the best efficiency can be changed dependent on distribution of non-zero elements in a matrix. This finding could be applied to heighten the efficiency of time and storage space for national datum readjustment and other large geodetic network adjustment.

• Educational Technology International
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• v.10 no.2
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• pp.63-83
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• 2009

The purpose of this study was to investigate the cognitive mechanism of e-Learning contents development projects on the basis of the Shared Mental Model theory perspective. To pursue the purpose, a theoretical model and several hypotheses were developed based on relevant literature. Thirty five (35) e-Learning contents development teams composed of 202 instructional designers from for-profit professional e-Learning companies in Korea were participated in this study. For the analyses of the fit of the Model and parameter estimations, Structural Equation Modeling (SEM) method was employed. As hypothesized, e-Learning contents development team members' interaction leads to higher SMMs which in turn facilitate member satisfaction within the team. Meanwhile, the frequency of interaction among team members decreases as projects progress.

• Membrane Journal
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• v.18 no.3
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• pp.206-213
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• 2008

Poly(vinylidene fluoride) (PVDF) membrane surfaces were modified using surface modifying macromolecules (SMMs). The Zonyl BA-L as SMM was used and the various PVDF membranes containing 0 to 2 wt% SMM were prepared. The resulting membranes were characterized through SEM, contact angle measurements and pervaporation separation of water-ethanol system. SMM layers were created in the surface regions of PVDF membranes by SEM images and the contact angles were increased more than untreated PVDF membranes. The pervaporation was carried out at 50, 60 and $70^{\circ}C$, and the PVDF membranes containing 1 and 2 wt% SMM were used for 10, 20, 50 wt% water in the binary water/ethanol mixtures and pure water. PVDF/2 wt% Zrlnyl BA-L membrane showed the permeability 5.3 $g/m^2hr$ and separation factor 287 at $50^{\circ}C$ for water : ethanol = 10 : 50 solution.

• Journal of the Korean Operations Research and Management Science Society
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• v.34 no.2
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• pp.1-13
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• 2009

In this paper, we develop theoretical game models to determine the level of government subsidies for banks to provide policy loans to Innovative SMEs(small and medium sized enterprises) through banks, which otherwise would not finance them for the sake of their own profitability. For this, we compare net cash flows of each bank using different strategies against high risk innovative SMEs. A bank can decide whether to provide them loans or not In each period. Following Kim(2003)'s Infinite horizon model on the soft budget constraint, we introduce a situation in which banks compete against each other for higher net long-term payoffs from their loans to innovative SMEs and non-innovative SMEs. From the models, we show that competition among banks in general leads to a tighter decision against innovative SMEs, as a Nash equilibrium. It is not because the government bank is simply loose in providing loans, but because competition among commercial banks for fewer riskier borrowers results in tighter loan decisions against innovative SMEs. Thus, the competitive market for policy loans to innovative SMEs fails to reach the socially optimal level of loans for innovative SMMs. Commercial banks in the competitive market may require additional supports from the government to make up for the differences in their payoffs to support innovative SMEs, possibly much riskier due to moral hazards and poor discounted cash flows. The monopolistic government bank might also request such supports from the government to fund otherwise unqualified SMEs. We calculate an optimal level of governmental support for banks to guarantee funding such high-risk innovative SMEs over periods without deviating from their optimal Nash equilibrium policies.

• The Journal of the Korea Contents Association
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• v.17 no.8
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• pp.366-381
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• 2017

This study was conducted in order to evaluate validity and reliability of the Korean version scale to measure maternal satisfaction in normal birth(KSMMS-normal birth). The SMMS-normal birth was administered to 205 postnatal women, together with the perception of birth experience scale. An exploratory factor analysis revealed six factors solution for the twenty three-item scale. Confirmatory factor analysis supported good convergent and discriminant validities, and factor correlations ranged from 0.11 to 0.57. The KSMMS-normal birth showed good concurrent validity with the perception of birth experience scale. The Cronbach alpha for the total scale was .91. It ranged between .80 to .90 for six subscales. The KSMMS-normal birth is reliable and valid instrument to measure maternal satisfaction. Therefore this scale can be used to assess maternal satisfaction in normal birth at hospital during the postpartum 2nd and 3rd day.