• Journal of the Society of Cosmetic Scientists of Korea
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• v.30 no.1
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• pp.123-128
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• 2004

Numerous novel ingredients have been introduced for the higher functionality of whitening cosmetics. Through the preliminary research, we have found Trichosanthes kirilowii root, Prunella vulgaris leaf and Clematis chinensis root have high whitening efficacy. But they are insoluble. Moreover the discoloration of and decrease in content take place when they are exposed to light, heat or oxygen. From Trichosanthes kirilowii root, Prunella vulgaris leaf and Clematis chinensis root, efficacious ingredients were ethanol-extracted by heating to 75∼85$^{\circ}C$ for 6∼8 h. These extracts have the inhibitory activity of tyrosinase and B16 melanin formation, thus enhancing whitening effect. We made liposomes using propylene glycol (PG)/hydrogenated lecithin/middle chain triglycerides (MCT)/glycerin/water and microfuidizer to stabilize extracts. The stability against heat and light was enhanced by 3∼5 times compared with untreated extracts. Particle size analyzer, freeze fracture transmission electron microscopy (FF-TEM), chromameter and HPLC are used for the analysis.

• Polymer(Korea)
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• v.28 no.6
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• pp.502-508
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• 2004

Cationic liposomes for cancer treatment have been developed in the field of chemotharpy. It was well combined on the surface of anionic tumor cell membrane by electrostatic interaction. Thus, the object of this study was to prepare the cationic liposomes capable of forming an ionic complex with the anionic cell membrane. To prepare the cationic liposomes, 1,2-distearoyl-sn-glycero-3-phosphoethanolamine (DSPE) as a cationic lipid material and polyethylenimine (PEI) as a cationic polymer were synthesized. Ionic property on the surface of liposomes was determined by the zeta potential. The adsorption characteristics of plasma protein for liposome in bovine serum were determined by the particle size and turbidity change. To estimate the stability of liposome in buffered solution, the change of particle size was measured at room temperature for seven days. The cationic liposomes were absorbed a large amount of plasma protein in bovine serum because plasma protein having anionic charge was fixed on the surface of cationic liposomes. This result indicate that the modification on the surface of liposomes using cationic polyethylenimine enhances the protein adsorption in bovine serum. Additionaly, cationic liposomes showed good stability in buffered solution for seven days.

• Journal of the Mineralogical Society of Korea
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• v.17 no.4
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• pp.327-338
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• 2004

XRD studies on annealed Na-feldspar (Amelia albite) at $1100^{\circ}C$ showed rapid structural changes due to Si-Al disordering, which resulted in phase transformations from low albite to high albite by 4-days annealing test. TEM SAED analyses on the annealed samples revealed a trend of structural changes, but estimation of the structural state was difficult due to a large deviation of the SAED data. Optimum conditions of CBED analyses on albite was established by employing a cooling specimen holder, 120 kV of acceleration voltage, 37 Jim of condenser aperture size and 25 nm of spot size. A proper orientation showing distinct changes of HOLZ lines corresponding to the structure changes of albite turned out to be close to the [418] direction with $-1.2^{\circ}$ tilting, where the width of two HOLZ lines in low albite was opposite to those in high albite.

• Journal of Korea Water Resources Association
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• v.37 no.5
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• pp.353-361
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• 2004

Effective storage in agricultural reservoir has been determined through the reservoir simulation operation based on the water budget analysis. Since each watershed has the native property for runoff, considering the runoff yielding from the basin is feasible to the determination of reservoir effective storage. In this study the stochastic linear programming model considering mainly runoff from watershed has been also formulated to analyze the effective storage of the exiting reservoir. The linear decision rule coupled with chance-constrained model in the linear programming model contributes to reduce the size of linear program model without considering the period of analysis. The Geum-Gang reservoir located in Ansung have been adopted to evaluate the effective storage. It has been shown that the effective storage based on the linear programming model is greater than that based on the water budget analysis. It has been also desired that once the effective storage is obtained through the linear programming model, operation of the reservoir should be performed to check the designed capacity.

• Journal of the Korea Concrete Institute
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• v.16 no.3 s.81
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• pp.383-390
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• 2004

This study has focused on the possibility for recycling tailings from the Sangdong tungsten mine as admixture for concrete. The XRD(X-ray diffraction analysis) and PSA(Particle size analysis) were performed to find mineralogical characteristics. As a result of XRD analysis, the tailings from the Sangdong tungsten fine were composed of quartz, chlorite, anorthite and cordierite etc. As a result of KSLT for cement mortar mixed with tailings from the Sangdong tungsten mine, most of heavy metals were determined as below the guide line for waste material. In addition, the setting time and compressive strength of cement mortar mixed with tailings from the Sangdong tungsten mine were investigated. It was indicated that the initial and final set were retarded according to increasing replacement of tailings from the Sangdong tungsten mine. The compressive strength of mortar was decreased with increasing replacement of failings from the Sangdong tungsten mine.

• Journal of the Korea Concrete Institute
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• v.16 no.6 s.84
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• pp.759-766
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• 2004

The addition of steel fiber with concrete significantly improves the engineering properties of structural members, notably shear strength. The purpose of this study is to determine the steel fiber shape, aspect ratio and volume fraction ratio in a point of practical usage as structural members. Steel fiber factor and volume fraction are also considered to verify the strengthening effect in member level. From the reviewing of previous researches and analyzing of consecutive material test results, the optimum shape and length of steel fiber, which can have a good strengthening effects were defined as a hooked end type and larger than 1.5 times of maximum gravel size. Analyzing the test results of strength and deformation capacity, aspect ratio 75 and volume fraction $1.5\%$ can be having a maximum strengthening effect of steel fiber. Also steel fiber factor, tensile splitting strength, and flexural strength are found as key parameter in shear strengthening effect in member level.

• Ocean and Polar Research
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• v.26 no.2
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• pp.113-120
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• 2004

The abundance, biomass and distribution of phytoplankton, bacterioplankton and heterotrophic protists in the Bering Sea were investigated from July to August 1999. Chlorophyll a concentrations in the surface waters ranged from 0.16 to $3.79{\mu}g\;l^{-1}$ Nano-phytoplankton were found to constitute from 63 to 98% of the total phytoplankton biomass, and were clearly the dominant primary producers. The biomass of bacterioplankton in the surface layers varied from 1.46 to $20.2{\mu}g\;C\;l^{-1}$ and accounted for 30% of the total phytoplankton biomass. The biomass of bacterioplankton integrated over a depth of 0 to 100m averaged 65.4% of the total phytoplankton biomass. The surface biomass of heterotrophic protists ranged from 1.2 to $27.4{\mu}g\;C\;l^{-1}$, and was within the same order of magnitude as that of bacterioplankton. Of the total biomass of heterotrophic protists in the upper 100m of the water column, 65% was attributed to protists in the nano-size class. The results of this study suggest that bacteria and nano-protists are important components of the planktonic community in the Bering Sea during the summer season. The abundance of bacterioplankton and planktonic protists decreased from the western to northeastern and eastern regions of the Bering Sea. The abundance of these organisms also decreased with depth. The available evidence suggests that variation in the abundance and distribution of these organisms may be affected by water currents and vertical temperature variation in the Bering Sea.

• Journal of Navigation and Port Research
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• v.28 no.3
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• pp.253-258
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• 2004

There have been several problems in treating shipbard sewage due to special environmental conditions of ship, such as limited space, rolling and pitching, change of temperature and so on It was suggested that Sequence Batch Reactor (SBR) might be suitable process for overcome these problems in terms of small size, high capacity of treating wastewater and full automation. In this study a SBR process was employed for biological treatment of organic wastes in the shipboard sewage. This process was able to remove nitrogen and phosphorus as well as organic matter efficiently. Afore than 95％ of chemical oxygen demand(COD) were removed. In addition, about 97％ of total nitrogen (T-N) was reduced. The total phosphorus(T-P) reduction averaged 93％. A disturbance operation caused by the treatment of Methylene Blue Active Substances(MBAS) was not observed.

• The Journal of the Korea Contents Association
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• v.11 no.9
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• pp.372-383
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• 2011

Our study was carried out to develop the severity-adjustment model for length of stay in hospital for percutaneous coronary interventions so that we would analysis the factors on the variation in length of stay(LOS). The subjects were 1,011 percutaneous coronary interventions inpatients of the Korean National Hospital Discharge In-depth Injury Survey 2004-2006 data. The data were analyzed using t-test and ANOVA and the severity-adjustment model was developed using data mining technique. After yielding the standardized value of the difference between crude and expected length of stay, we analysed the variation of length of stay for percutaneous coronary interventions. There was variation of LOS in regional differences, size of sickbed and insurance type. The variation of length of stay controlling the case mix or severity of illness can be explained the factors of provider. This supply factors in LOS variations should be more studied for individual practice style or patient management practices and healthcare resources or environment. We expect that the severity-adjustment model using administrative databases should be more adapted in other diseases in practical.

• Progress in Superconductivity
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• v.6 no.1
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• pp.56-63
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• 2004

We consider design factors for a SQUID sensor array to construct a 52-channel magnetocardiogram (MCG) system that can be used to measure tangential components of the cardiac magnetic fields. Nowadays, full-size multichannel MCG systems, which cover the whole signal area of a heart, are developed to improve the clinical analysis with high accuracy and to provide patients with comfort in the course of measurement. To design the full-size MCG system, we have to make a compromise between cost and performance. The cost is involved with the number of sensors, the number of the electronics, the size of a cooling dewar, the consumption of refrigerants for maintenance, and etc. The performance is the capability of covering the whole heart volume at once and of localizing current sources with a small error. In this study, we design the cost-effective arrangement of sensors for MCG by considering an adequate sensor interval and the confidence region of a tolerable localization error, which covers the heart. In order to fit the detector array on the cylindrical dewar economically, we removed the detectors that were located at the corners of the array square. Through simulations using the confidence region method, we verified that our design of the detector array was good enough to obtain whole information from the heart at a time. A result of the simulation also suggested that tangential-component MCG measurement could localize deeper current dipoles than normal-component MCG measurement with the same confidence volume; therefore, we conclude that measurement of the tangential component is more suitable to an MCG system than measurement of the normal component.