• Current Optics and Photonics
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• v.2 no.1
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• pp.23-26
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• 2018

Optical-layer restoration has been demonstrated with a wavelength-blocker (WB) -based reconfigurable optical add/drop multiplexer (ROADM). Two $2{\times}2$ optical switches with a control circuit were placed before and after a WB-based ROADM to provide automatic path restoration under fiber-failure conditions. Using the proposed node configuration, a 3-node self-healing ring (SHR) network has been implemented to demonstrate the feasibility of the automatic optical-layer restoration. From the results, the restoration time was measured to be ~4 ms under fiber-failure conditions, without any additional power penalty in receiver sensitivity.

• YAKHAK HOEJI
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• v.28 no.5
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• pp.249-256
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• 1984

The effects of $Ca^{2+}-antagonist$, cinnarizine, on the antihypertensive effects of propranolol and metoprolol were investigated in normal cat (i. v.) and SHR (p. o.). Cinnarizine increased the antihypertensive effect of propranolol, but not of metoprolol. It inhibited the heart rate decreasing effects of propranolol and metoprolol slightly. It decreased the norepinephrine-induced blood pressure increasing effect and isoproterenol-induced blood pressure decreasing effect when coadministered with metoprolol orally for 4 weeks in SHRs.

• YAKHAK HOEJI
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• v.28 no.5
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• pp.257-263
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• 1984

In our former report we observed that cinnarizine influenced the antihypertensive effect of propranolol beneficially, but not of metoprolol in SHR and normal cat. Cardiac contractilities and smooth muscle relaxations induced by above drugs were measured to elucidate their mechanism of action. In cinnarizine and propranolol treated group, both of negative inotropic and ${\beta}-blocking$ activity of propranolol in perfused rat hearts were increased and propranolol induced contraction in isolated arterial and trachea smooth muscle of the guinea pig was antagonized comparing to propranolol alone treated group. However, in the cinnarizine and metoprolol treated group, no significant differences in activity on the above were observed compared to metoprolol alone treated group.

• Korean Journal of Pharmacognosy
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• v.11 no.2
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• pp.61-65
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• 1980

As a folkloric medicine, Siegesbeckia pubescens has been used for treatment of brain stroke and hypertension. Diterpene compound, 16,17-dihydroxy 16-${\beta}-(-)$ kaurane-19-oic acid, was isolated from the plant. Its potential antihypertensive activity was evaluated againstan animal model of hypertension, Okamoto-SHR. When diterpene compound with dose of 50mg/kg/day was orally administered, it exhibited mild antihypertensive activity comparable with propranolol administration dose of 75mg/kg/day.

• Bulletin of Food Technology
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• v.12 no.3
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• pp.8-13
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• 1999

키틴/키토산은 지질흡수의 억제, 혈중 콜레스테롤의 저하, 항고혈압활성, 면역활성, 항종양/항암활성 등 다양한 생체기능성을 나타내어 건강지향적인 기능성 식품으로서의 이용가치가 매우 큰것으로 평가되고 있다. 키토산은 성인남자의 혈중 콜레스테롤을 감소시키고 HDL cholesterol은 증가시켜 동맥경화지수를 낮추며 비만환자에게 투여시 체중, 중성지질, LDL cholesterol을 유의하게 낮춤으로서 고지혈증과 비만증의 개선에 유용한 것으로 평가된다. 키토산은 또한 성인의 고염식에 의한 혈압상승을 억제하며 3량체 내외의 키틴/키토산 올리고당은 혈압상승의 중요인자인 angiotensin converting enzyme과 직접 반응하여 활성을 현저히 저하시키고 SHR에서의 혈압을 유의하게 억제하는 특성을 보여 고혈압의 억제 및 치료에도 응용가치가 클 것으로 생각된다. 키틴/키토산 및 그 올리고당은 sarcoma 180, Meth-A solid tumor의 성장을 저해하고 L1210와 같은 negative charge를 갖는 malignant cell을 흡착시키는 등 항종양/항암활성을 보이는데 이는 tumoricidal immunocite의 활성화에 의한 것으로 추정되고 있다. 키틴/키토산의 생체활성은 분자크기, 탈아세틸화도, 유도체의 종류 및 적용방법 등에 따라 차이를 보이기 때문에 키틴/키토산을 기능성 식품으로서 폭넓게 이용하게 위해서는 용도에 맞는 적절한 규격 설정이 요구되고 있다.

• The Journal of Korean Physical Therapy
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• v.14 no.3
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• pp.297-307
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• 2002

We have isolated a sesquiterpene lactone, cumambrin A from the dried flowers of Chrysanthemum boreale Makino and reported its chemical structure. The aim of the present study was to investigate whether the exogenous administration of cumambrin A has a pharmacological effect on normalization of blood pressure in the spontaneously hypertensive rats (SHR). In vitro studies: Relaxative response induced by cumambrin A was increased with dose-dependent manner and showed maximizing response at a concentration of 5?0-4 M. Further, this relaxative response was significantly increased at a condition of endothelium present than that of endothelium denuded. in vivo studies: The normalizing effect of cumambrin A on blood pressure was also increased with time-dependent manner and then gradually recovered to normal condition at approximately 4 hrs after cumambrin A treatment.

• Proceedings of the Korean Operations and Management Science Society Conference
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• 1994.10a
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• pp.337.1-337
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• 1994

동기식 광전송망에서는 망의 생존도를 고려하여 다양한 형태의 망구조가 제안되고 있다. 본 연구에서는 수요가 한 방향으로만 처리되는 ADM을 이용한 USHR선정문제를 다룬다. USHR설계문제에서는 노드간의 수요를 처리하기 위하여 장비의 위치선정, ADM간의 연결을 위한 Ring 경로선정문제, ADM이 설치되지 않은 노드와 ADM간의 연결방법, Ring용량결정등 많은 의사 결정이 이루어져야 한다. 특히 주어진 노드 간에 하나 이상의 SHR을 설치해야 하는 경우에는 매우 복잡한 문제가 되기 때문에 최적화 모형을 수립하여 문제를 해결하는 것이 불가능하다. 따라서 본 연구에서는 주어진 노드집합에 대하여 모든 노드에 ADM이 설치되는 가정하에서 Ring의 용량제약을 고려한 USHR선정모형 및 효과척인 해법을 제시한다.

• International Journal of Aerospace System Engineering
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• v.2 no.1
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• pp.18-23
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• 2015

Based on real jobs, this study was carried out the Railway maintenance works in Taiwan. It hopes to use Geographic Information System(GIS) and Building Information Modeling(BIM) for changing the maintenance model from "post-damage repair" to "preventive maintenance". Accordingly, this research will build a Railway Repairing Database that installs all repair data. This database will also connect to GIS so that can be the source of analysis and statistic for repair paln. The main results of research are as follows: I. All data stored on cloud space that raises the ability to manage and plan on repair. II. Simplify the file work and increase the quantity of case data to the manager who can get more reliable source. III. The data offer objective judgment to avoid subjective argument. IV. Add the GIS information to improve the maintenance because of good analisis.

• International Journal of Aerospace System Engineering
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• v.2 no.2
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• pp.15-18
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• 2015

In general, most of the function and using of building is for single purpose. However, current buildings combine several functions that causes a lot of problems not on firefighting only but also on environment engineering. Because of hard integration on different fields that causes a lot of conflict. That wastes cost and time. That also threaten the safety of firefighting. This search focuses on the drawing verification and field inspection on firefighting. These two items both remain paper work. To complete the current work, it needs to bring a great amount of drawing papers in the field. By BIM, integrated data can be extracted. It makes the drawing verification and field inspection easier and increases the efficiency. That is the main point of this research.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.32 no.6A
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• pp.511-518
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• 2007

One of the major issues that has to be carefully considered when upgrading current transport network capacity, is network scalability. A novel full-meshed connected ring expansion methodology and planning tool have been proposed. A 3 to 15 node expansion ring has been studied by demonstrating a dramatic system SNR improvement when the proposed planning tool was used. The results are that node output signal and optical SNR have been improved from -16dBm/10dB to +005dBm/21dB by NPOT.