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Health Related Quality of Life among Organ Transplant Recipients (장기이식환자의 건강관련 삶의 질)

  • 김금순;강지연;정인숙
    • Journal of Korean Academy of Nursing
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    • v.33 no.3
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    • pp.365-375
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    • 2003
  • Purpose: This study was aimed to investigate the health related quality of life and related factors of organ transplant recipients. Method: The participants were 188 people who had liver(86), kidney(81), or heart(24) transplanted. Data on the demographic characteristics, transplantation-related characteristics, symptom frequency or discomfort measured by Transplant Symptom Frequency and Symptom Distress Scale by Lough et al(l987), and health related quality of life measured by SF-36(version 2) were collected. Result: Overall health related quality of life score was 492.1 for 100scoring and, 344.9 for norm based. Physical functioning showed the highest quality of life score (77.5) and vitality showed the lowest(51.l). The kidney transplanted showed the highest quality of life (504.4) and the heart transplanted showed the lowest(426.7) Quality of life was related with occupation(p=.016) and symtom discomfort(p < .0001). Conclusion: The health related quality of life of transplated patients was lower than the norm of American. Further studies need to be done to identify the norm of Korean and to investigate the effect of releving symptom discomfort on the increasing the health related quality of life.

Molecular Cloning and Characterization of a Vitellogenin of the Bumblebee Bombus ignitus

  • Lee, Kyung-Yong;Yoon, Hyung-Joo;Lee, Sang-Beom;Park, In-Gyun;Sohn, Hung-Dae;Jin, Byung-Rae
    • International Journal of Industrial Entomology and Biomaterials
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    • v.18 no.1
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    • pp.33-40
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    • 2009
  • A vitellogenin cDNA was cloned from the bumblebee Bombus ignitus. The cDNA encoding B. ignitus vitellogenin (BiVg) is 5473 bases long with an open reading frame of 1773 amino acid residues. BiVg possesses two consensus (RXXR/S) cleavage sites and has the conserved DGXR and GL/ICG motif near its C-terminus. The deduced amino acid sequence of BiVg cDNA showed significant similarity with hymenopteran Vgs (51% identity to Apis mellifera Vg, and $33{\sim}36%$ to other insect Vgs). The BiVg cDNA was expressed as a 200-kDa polypeptide in baculovirus-infected insect Sf9 cells. Northern and Western blot analyses showed the expression of BiVg in fat bodies of pupae and adults. In queens, the expression of BiVg was first detected in late pupal stage fat bodies, and secreted BiVg was also observed in late pupal stage hemolymph.

Personal Resource and Parenting Stress of Mothers of Children with Congenital Heart Disease (선천성 심장병을 가진 아동의 어머니의 개인적 자원과 양육스트레스)

  • Lee, Sun-Hee;Yoo, Il-Young
    • Child Health Nursing Research
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    • v.13 no.1
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    • pp.73-80
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    • 2007
  • Purpose: As a result of dramatic advances in the medical and surgical management of congenital heart disease (CHD), many babies born with cardiac anomalies today can expect to reach adulthood. The main purpose of this study was to examine the relationship between parenting stress and personal resources of mothers of children with CHD. Method: Fifty-one mothers of children with CHD were recruited at the pediatric cardiac outpatient clinic from July 14th to September 25th 2006. Abidin's parenting stress index/short form (PSI/SF) and Brandt and Weinert's personal resource questionnaire (PRQ) were used. PSI has 3 sub-concepts; parental role distress, dysfunctional parent-child interaction, and difficult child. PRQ has 4 sub-concepts; intimacy, social integration, worth, and assistance. Data were analyzed using SPSS 13.0 version. Results: Correlation analysis showed that parenting stress was significantly related to 'intimacy', 'social integration', and 'worth' of mothers. Multiple regression analysis showed that parenting stress was significantly related to personal resource of mother and information by internet. Conclusion: Mothers who felt they had supportive friends and family, high self esteem, and social integration reported lower parenting stress. Also, internet may be an effective method to provide information and share experience for mothers of children with CHD.

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Design of Residual Treatment Process with Filter Backwash Recycle System (역세척수 회수시스템이 포함된 배출수처리공정의 설계)

  • Bae, Byung-Uk;Choi, Kyung-Hwan
    • Journal of Korean Society on Water Environment
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    • v.28 no.1
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    • pp.109-114
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    • 2012
  • In this study, both sedimentation and thickening experiments were conducted for residuals produced from an advanced water treatment plant for more accurate and practical design of residual treatment train. In order to design a backwashed residual sedimentation basin (SRSB) in the filter backwash water recycle system, two kinds of backwash waters, one from sand filter (SFBW) and the other from GAC adsorption bed (GACBW), were separately collected and their surface loading rate measured. In addition, in order to design a gravity thickener, batch thickening tests were conducted for concentrated residuals taken from sedimentation basin and their limiting solid flux ($SF_{L}$) measured. From the experimental results and consideration of the seasonal characteristics of the residual, surface loading rate of $70m^{3}/m^{2}{\cdot}d$ was proposed as a design parameter for SRSB and solid loading rate of 20 kg $TS/m^{2}{\cdot}d$ was proposed as a design parameter for gravity thickeners. Finally, the material mass-balance was made for the design of each unit process in the residual treatment train.

Transposition of IntAs into the Conserved Regions of IS3 Family Elements

  • Han, Chang-Gyun
    • Journal of Microbiology
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    • v.42 no.1
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    • pp.56-59
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    • 2004
  • Together with the previous reports, my computer survey revealed that several bacteria contain six copies of the type group II intron IntA. The sequence analysis of IntAs showed the high level of homology in the nucleotide sequence (91.9-99.8%). The consensus sequence, 2,270 base pair long, was derived from the nucleotide sequences of all IntA members. The size of the open reading frame intA was 502 amino acids long, that is homologous to reverse transcriptase-like proteins encoded within the group II introns. It was reported that EPEC.IntA and Sf.IntA were inserted into IS911 and IS629, respectively. The sequence of the flanking region IntA was analyzed here. The data show the insertion of EC.IntA into IS629, the insertion of EHEC.IntA into IS3, the insertion of Yp.IntA into IS904-like sequence, and the insertion of EK12.IntA into IS911. Interestingly, these IS elements nested by IntAs were the members of IS3 family elements. The sequences of the IS3 members correspond to the OrfB with the DDE motif conserved in retroviral integrases. Alignment of the flanking sequences of IntAs revealed that the flanking regions -25 to + 10 of insertion sites, that are generally believed to be required for the retrohoming, were not strongly conserved. The data presented here suggests that the retrohoming pathway of IntA seems to differ from those of other group II introns.

Factors associated with Health-related Quality of Life in Vulnerable Elderly Women (취약계층 여성노인의 연령주기별 건강관련 삶의 질 관련 요인)

  • Shin, Gyeyoung;Kim, Eun Kyung
    • Journal of Korean Public Health Nursing
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    • v.28 no.3
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    • pp.419-431
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    • 2014
  • Purpose: The aim of this study was to understand the determinants of health-related quality of life (HRQOL) according to age groups in vulnerable elderly women. Methods: We conducted a cross-sectional study with 1,533 elderly women beneficiaries of the visiting health care program in Seoul. The participants were divided into three age groups: the young-old (n=753, 65-74 years), old-old (n=602, 75-84 years), and oldest-old (n=178, 85 years or older) groups. HRQOL was measured using the SF-8 questionnaire. Results: HRQOL was found to be worse in the oldest-old group (p=.007). Factors associated with HRQOL differ by age groups. In the young-old and old-old groups, higher HRQOL showed significant correlation with a higher level of self-rated health (SRH) and a lower level of depression, instrumental activities of daily living (IADL) dependence, and the number of chronic diseases. In addition, higher HRQOL was observed for elderly living alone than for those living with family. In the oldest group, higher HRQOL showed significant correlation with a lower level of depression, activities of daily living (ADL) dependence, and a higher level of SRH. Conclusions: In age specific groups, lower levels of HRQOL were observed for the oldest-old group than for the other age groups. Age group-specific nursing strategies may be required for improving HRQOL levels of vulnerable elderly women.

The Relationship between Social Support, Health Status, College Adjustment and Academic Achievement in College Students (대학생들의 사회적 지지와 건강상태, 대학생활 적응 및 학업성취도와의 관계)

  • Jeon, So-Youn
    • The Journal of Korean Society for School & Community Health Education
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    • v.11 no.1
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    • pp.93-115
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    • 2010
  • Objectives: This study intends to understand the difference of social support levels and the relationship between social support the health status, college adjustment and academic achievement in the college student. Methods: Data were obtained from self-administered questionnaire of 416 college student. We measured the demographic characteristics, social support (tangible support, appraisal support, belonging support, self-esteem support), health status (36-item short-form health survey(SF-36), center for epidemiologic studies-depression(CES-D), perceived stress scale(PSS)), student adaptation to college questionnaire(SACQ), average grades point. Chi-square test, t-test, ANOVA test, pearson correlation analysis were used for analysis factors relation of the social support of the college students. Results: In considering the degree of social support by the demographic characteristics in the college students, the social support was better for the female college students. In considering the relation between social support and health status, the students who get better social support, were good in health depression and perceived stress status. When they got better social support their college adjustment and academic achievement were good. The result was statistically significant. Conclusions: Social support for students has great influence on health, college adjustment and academic achievement of students. Psychological aspects of students should be included in the strategy of social support for students.

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Molecular Cloning, Gene Structure, Expression, and Enzyme Activity of a Serine Protease from Water Scorpion, Laccotrephes japonensis (Hemiptera: Nepidae)

  • Park, Kwan Ho;Choi, Young Cheol;Nam, Seong Hee;Hwang, Jae Sam;Nho, Si Kab
    • International Journal of Industrial Entomology and Biomaterials
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    • v.25 no.2
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    • pp.187-193
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    • 2012
  • Serine proteases are major insect enzymes involved in the digestion of dietary proteins and in the process of blood meal digestion. In this study, cDNA was constructed using the whole body of Laccotrephes japonensis. The flanking sequences of the 5- and 3- end of this gene were characterized by RACE-PCR. Sequence analysis showed that this gene contained a 963-bp ORF encoding 320 amino acids. The deduced amino acid sequence showed 62% identity with the Creontiades dilutus serine protease, 58% with the Lygus lineolaris trypsin precursor, and 54% with the Triatoma infestans salivary trypsin. To assess the expression of the L. japonensis serine protease (JGsp), the JGsp gene was cloned into a baculovirus transfer vector, pBac-1, and expressed in Sf9 cells (Spodoptera frugiperda). SDS-PAGE and western blot analysis have shown that the JGsp recombinant protein was a monomer with a molecular weight of about 32 kDa. Recombinant JGsp has shown activity in the protease enzyme assay using gelatin as a substrate.

Surface Discharge Characteristics in Dry-Air (Dry-Air의 연면방전 특성)

  • Park, He-Rie;Choi, Eun-Hyuck;Lee, Sang-Ho;Park, Sung-Gyu;Kim, Jung-Bae;Park, Kwang-Seo;Kim, Lee-Kuk;Lee, Kwang-Sik
    • Proceedings of the KIEE Conference
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    • 2008.05a
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    • pp.125-126
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    • 2008
  • 본 연구에서는 챔버 내에 압력 $1{\sim}7$[atm]의 Dry-Air를 주입한 후, AC전압을 인가하여, 전극의 모양에 따라 불평등 전계/준평등 전계를 형성하였을 시, 전극 사이에 넣은 고체절연물의 두께에 따른 연면방전 특성을 실험을 통하여 측정 비교한 것이다. 고체절연물로는 열경화성 플라스틱을 사용하였다. 챔버 내 Dry-Air의 주입압력이 높일수록 연면 절연파괴 전압이 높았고, 준평등 전계에서보다 불평등 전계 인가시 더 높은 절연파괴 저압을 얻을 수 있었다. 또한 고체절연물의 두께가 두꺼울수록 고체의 절연파괴 전압이 높았으며, 고체절연물의 두께가 2[mm]일 경우, Dry-Air의 연면방전 특성이 $SF_6$보다 평균적으로 $12{\sim}51$[%] 낮고, 3[mm]의 경우도 Dry-Air의 연면방전 특성이 $14{\sim}45$[%] 가량 낮았다.

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Bacterial Sporulation and germination of Biocontrol agent Bacilus subtilis YBL-7 (항진균성 길항세균 Bacillus subtilis YBL-7의 종자피막용 포자체의 생산과 발아조건)

  • 장종원;김상달
    • Microbiology and Biotechnology Letters
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    • v.23 no.2
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    • pp.236-242
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    • 1995
  • Biological control of soilborne plant pathogens by the addition of antagonistic microorganisms to the soil may offer a practical supplement or alternative to existing disease management strategies that depend heavily on chemical pesticides. Soil amendment with antagonistic microbes was non-effective because of high cost, low efficacy, and inconvenient usage on the treatment course. Therefore, seed coating formulation for the application of biological seed treatments has been being to apply successful disease suppression for many important crops. The objectives of this study were to investigate the optimal condition for the spore production of biocontrol agent Bacillus subtilis YBL-7 and the liquid coating formulation that contained a suspension of a proper aqueous binder, as well as a ground fine solid particulate material. The maximum yield has been obtained from 60 hrs-old culture at 30$\circ$C in spore forming (SF) medium containing 0.8% nutrient broth, 0.05% yeast extract, 10$^{-1}$ M MgCl$^{2}$, 10$^{-4}$ M MnCl$^{2}$, 10$^{-5}$ M dipicolinic acid, and pH 6.5. The optimal condition of dried spore preparation was achieved when cells of B. subtilis YBL-7 was heat-dried with 50$\circ$C for 2 hrs.

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