• Physical Therapy Rehabilitation Science
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• 제8권1호
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• pp.22-31
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• 2019

Objective: For knee osteoarthritis (OA), there is a demand for alternative modalities in order to delay surgery and to avoid the side effects of medications. This study compared the effects of applying seaweed pack and mudpack for the treatment of knee OA. Design: Randomized controlled trial. Methods: Twenty-five patients with knee OA who satisfied the criteria were included. The patients were divided into two groups according to the treatment method: mudpack (n=12) and seaweed pack (n=13). The two groups were treated for 20 minutes, twice a day for five continuous days at the Ocean Healing Center at Wando Island, South Korea. Participants were assessed by clinical scores (Western Ontario and McMaster Universities Osteoarthritis Index, Hospital for Special Surgery Knee Score, Knee injury and Osteoarthritis Outcome Score and 36-Item Short Form Health Survey) and lab results (erythrocyte sedimentation rate, C-reactive protein, insulin-like growth factor-1 [IGF-1], tumor necrosis $factor-{\alpha}$ [$TNF-{\alpha}$]) during the follow-up period. Results: For the most part, clinical scores improved after therapy and maintained improvements for four weeks in both groups (p<0.05). In the seaweed group, $TNF-{\alpha}$ was significantly decreased at two weeks post-therapy (p<0.05). In both groups, IGF-1 was significantly increased immediately post-therapy (p<0.05). There were no statistically significant differences after therapy between the groups in clinical scores and labs. Conclusions: Seaweed packs and mudpacks had similar positive effects for knee OA. Additionally, the seaweed pack group showed decreased levels of $TNF-{\alpha}$ at two weeks post-treatment, which may explain the reduced inflammatory reaction. For rehabilitation therapy, use of seaweed packs may serve as an alternative modality for the treatment of knee OA.

• ALGAE
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• 제37권2호
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• pp.105-121
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• 2022

Modern seaweed farming relies heavily on seedlings from natural beds or vegetative cuttings from previous harvests. However, this farming method has some disadvantages, such as physiological variation in the seed stock and decreased genetic variability, which reduces the growth rate, carrageenan yield, and gel strength of the seaweeds. A new method of seedling production that is sustainable, scalable, and produces a large number of high-quality plantlets is needed to support the seaweed farming industry. Recent use of tissue culture and micropropagation techniques in eucheumatoid seaweed production has yielded promising results in increasing seed supply and growing uniform seedlings in large numbers in a shorter time. Several seaweed species have been successfully cultured and regenerated into new plantlets in laboratories using direct regeneration, callus culture, and protoplast culture. The use of biostimulants and plant growth regulators in culture media increases the seedling quality even further. Seedlings produced by micropropagation grew faster and had better biochemical properties than conventionally cultivated seedlings. Before being transferred to a land-based grow-out system or ocean nets for farming, tissue-cultured seedlings were recommended to undergo an acclimatization process to increase their survival rate. Regular monitoring is needed to prevent disease and pest infestations and grazing by herbivorous fish and turtles during the farming process. The current review discusses recent techniques for producing eucheumatoid and other valuable seaweed farming materials, emphasizing the efficiency of micropropagation and the transition from laboratory culture to cultivation in land-based or open-sea grow-out systems to elucidate optimal conditions for sustainable seaweed production.

• 한국수산과학회지
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• 제40권3호
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• pp.122-127
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• 2007

Photosensitized extracts of 28 seaweed species were tested in vitro to examine the variation in their algicidal activities against the toxic microalga Cochlodinium polykrikoides. When both seaweed extracts and microalgae were exposed to UV and visible light, methanol extracts of Porphyra yezoensis showed 5.7- and 4.4-fold increasesin light-dependent algicidal activity, respectively. When only seaweed extracts were exposed to both UV (365 nm) and visible light (white lamp) at the same time, methanol extracts of Enteromorpha linza and Carpopeltis affinis showed 3.3- and 3.4-fold increases in algicidal activity, respectively. When UV-photosensitized extracts were left in the dark, the algicidal activity of Ecklonia cava increased 13-fold after 5 h. When visible light-photosensitized extracts were left in the dark, the algicidal activity of Monostroma nitidum increased by 3.3-fold in 1 h.

• Fisheries and Aquatic Sciences
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• 제21권7호
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• pp.19.1-19.11
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• 2018

Background: Traditionally, East-Asians (Korea, Japan, and China) utilize seaweeds as a food source and ingredient in traditional medicine. Korea is one of the biggest seaweed producer and consumer in the global trade. Especially, side dishes made from seaweeds are very popular in the traditional Korean cuisines. Seaweeds are popular as fresh vegetable salads and soup or eaten as snacks. Main body: Seaweeds are rich in essential nutrients, minerals, and vitamins as well as a promising source of novel bioactive compounds. The compounds (polysaccharides, polyphenols, and sterols) present in the edible Korean seaweeds possess important bioactive properties such as antioxidant, anti-inflammation, anticancer, anti-diabetic, and anticoagulant properties. Thus, the long-term consumption of seaweed has a potential to reduce the risk of cancer, diabetes, obesity, and inflammation-related complications. However, seaweed consumption is limited to the small population around the globe. Thus, it is important to increase the awareness of the health benefits of seaweeds consumption among the general population. Short conclusion: In the present study, we discussed some popular green and red edible Korean seaweeds and their health-promoting properties. This study might be useful to increase the public awareness of the consumption of seaweed as a food source.

• 한국가금학회:학술대회논문집
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• 한국가금학회 2004년도 제21차 정기총회 및 학술발표회
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• pp.31-32
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• 2004

콩 추출물 함유 미역제품 2.0 % 사료가 급성기 반응중인 육계병아리의 생산성과 영양소 이용성에 미치는 영향을 조사하였다. 콩 추출물 함유 미역제품 2.0 % 사료는 급성기 반응시 감소된 사료섭취를 증가시키고, 급성기 반응시 뇨산태 질소의 배설량을 감소시켜 질소밸런스를 증가시켰다. 콩 추출물 함유 미역제품 2.0 % 사료는 4주령 체중을 높였다. 본 성적은 단백질 축적량의 증가는 단백질 분해량의 감소에 기인한다는 것을 나타낸다. 그리고 사료 중 콩 추출물 함유 미역제품이 육계병아리의 단백질 축적량을 증가시켜 생산성을 증가시키며, 급성기 반응시 사료섭취 증가와 영양소 이용성을 증가시킨다는 것을 나타낸다.

• 대한지역사회영양학회지
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• 제15권3호
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• pp.361-368
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• 2010

This study was carried out to investigate preference and purchase factors of seaweed in some regional residents of Korea. Subjects were residents (n = 1,218) whose residential area was divided into inland and coastal region and the survey was done during December 2007. Especially, purchase factors of seaweeds was conducted only in married females (n = 353). The subjects are composed of 46.5% male and 53.5% female. Regional distribution of subjects was found to be 16~17%, with highest ratio in the age bracket of 20~29 years old. Proportion of students, at 29.8%, was the highest ranking occupation of the subjects. Preference score of seaweeds by region was highest for laver followed by brown seaweed and sea tangle. In terms of preference by gender, female subjects displayed higher preference score for green laver (p < 0.01), seaweed fusiforme, brown seaweed, sea tangle (p < 0.001) than the male subjects. Considerations being made when purchasing seaweeds for each region were in the order of freshness, taste and nutrition. In comparing the inland and coastal region, scores of freshness, convenience, design and color for the coastal region was higher, displaying significant difference.

• 한국식품영양과학회지
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• 제23권1호
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• pp.156-163
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• 1994

To investigate the optimum conditions of seaweed Mooks prepared with sea mustard (Indaria pinnatifida) and sea tangel(Laminaria japonica), pH, viscosity , yield and jelly strength were studied on the sol and /or gel (Mook ) made from homogenized seaweeds. Solubilization conditions of homogenized seaweeds were heating at $65^{\circ}C$ for one hour after mixing homogenized seaweed with 1 % $K_2$HPO$_4$ by 1 ; 1 (v/v) . Gelation conditions were 24 hrs by natural permeation of Ca++ into the sol in three times (v/v) of 1 % CaCl$_2$ solution to solubilized seaweed passed through 60 mesh of sieve. There are generally no relationship between viscosity of solubilized seaweed and jelly strength of Mook produced by gelation of the sol in CaCl$_2$ solution . Jelly strength of sea mustard Mook was more than 500g/$\textrm{cm}^2$ , yield was 87.5% of the solubilized and filtrated seaweed . Jelly strength and specific gravity of sea tangle Mook were higher those of sea mustard Mook, while its yield was lower than that of sea mustard Mook.

• 한국재료학회지
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• 제34권2호
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• pp.95-104
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• 2024

Nanoparticles are commonly used to avoid the opaque white color of TiO₂ based sunscreen. However, a dispersing agent is typically required because of the tendency of the nanoparticles (NPs) to agglomerate. Stearic acid is one kind of dispersing agent often used for sunscreen products. However, according to the MSDS data sheet on stearic acid, stearic acid is highly hazardous to aquatic life and causes irritation on human skin. To avoid this problem, in this study a safer organic dispersing agent extracted from Korean seaweed has been studied to disperse TiO₂ nanoparticles, and further use as an active agent in sunscreen products. The presence of phytochemicals in seaweed extract, especially alginate, can disperse TiO₂ nanoparticles and improve TiO₂ dispersion properties. Results show that seaweed extract can improve the dispersion properties of TiO₂ nanoparticles and sunscreen products. Reducing the agglomeration of TiO₂ nanoparticles improves sunscreen properties, by making it less opaque white in color, and increasing UV protection value. It was also confirmed that adding seaweed extract into sunscreen products had no irritating effects on the human skin, making it more desirable for cosmetics application.

• 문화기술의 융합
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• 제4권2호
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• pp.161-169
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• 2018

본 연구는 해조 다당류 추출물을 화장품 원료로 사용할 수 있는지 평가하고자 하였다. 항균 효과를 평가하기 위해 해조 다당류 추출물로 부터 Staphylococcus aureus (S. aureus) 균주에 대한 항균활성을 측정하였다. 또한, RAW 264.7 세포에서 항염증 효과가 확인되었으며, 해조 다당류 추출물을 Sprague-Dawley (SD) 흰쥐의 등쪽 피부에 적용하여 단회투여독성을 평가하였다. 그 결과, 해조 다당류 추출물은 피부섬유 아세포에서 최대 $1,000{\mu}g/mL$ 농도에서 세포 독성을 나타내지 않았다. 또한, 1 % 해조 다당류 추출물로 처리되었을 때, $1.52{\pm}0.34cm$로 생육저해환이 형성되어 S. aureus 균주에 대한 항균 활성을 확인하였다. 해조 다당류 추출물을 RAW 264.7 세포에 처리하면 농도 의존적으로 산화 질소 (NO)의 생성이 감소하고 인터루킨 1 베타 ($IL1{\beta}$), 종양 괴사 인자 알파 ($TNF{\alpha}$)와 같은 염증 관련 사이토카인의 생성이 증가하였으며, 프로스타글란딘 E2 (PGE2)가 감소 하였다. 해조 다당류 추출물을 여러 농도로 흰쥐에 투여했을 때 증상은 14 일 이상 변하지 않았으며 췌장이나 장기 무게에는 변화가 없었다. 결론적으로 우리는 해조 다당류 추출물이 세포 독성을 나타내지 않았으며 항균 및 항염증 효과가 있음을 발견하였다. 따라서, 화장품 원료로 사용하기에 적합하다고 사료된다.

• 한국식품영양학회지
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• 제15권3호
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• pp.257-266
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• 2002

해조류 조직을 가수분해시켜 기호성 및 응용성이 높은 액상원료로 가공하는 기술 개발의 일환으로 우선 자연계에 존재하는 미생물로서 산, 논, 밭, 해변 및 어판장에서 약 200종류의 미생물군 시료를 수집하여 해조의 조직파괴가 인정되는 8군의 미생물 시료를 사용하여 돌가사리,톳 및 가시파래의 조직파괴와 가수분해 가능성에 대하여 검토하고,추출액 중의 전당과 환원당을 측정하여 추출율과 분해율을 비교하였다. 그 결과 돌가사리, 톳 및 가시파래의 전당 추출량과 추출율은 각각 담수에서 채취한 미생물군 시료(No.27번), 부식한 식물에서 채취한 미생물군 시료(No. 8번) 및 담수에서 채취한 미생물군 시료가 가장 높은 값을 나타내었고, 환원당의 추출량과 추출율에서는 각각 8번, 8번 및 27번 미생물군 시료가 가장 높은 값을 나타내었다. 분해율은 전당의 추출율도 상당히 높으면서 환원당의 추출이 가장 높았던 실험구들이 각각의 해조에서 가장 높은 분해율을 나타내는 결과를 얻었다. 따라서 이들 자연계에서 채취한 미생물군 시료중에 해조 조체를 파괴시키고, 또한 해조에 다량 함유되어 있는 당을 비롯한 유용성분의 추출을 용이하게 하며, 해조를 가수분해시키는 효소를 가진 미생물이 존재할 것으로 판단되었으며, 또한 이들 미생물군에서 단일 또는 복합 해조가수분해 미생물 및 효소의 생산이 가능할 것으로 기대되었다.