• Analyses & Alternatives
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• v.2 no.2
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• pp.111-141
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• 2018

By the middle of 2018 there are signs of China's entry into a new period of development, characterized by a change in the old model: "market reforms-inner-party democratization - moderate foreign policy" to another: "market reforms - Xi Jinping personality cult - offensive foreign policy." This model contains the risks of arising of the contradiction between economic freedom and political-ideological rigidity which can lead to destabilization of the political life. However, in the current positive economic dynamics, these risks may come out, rather, in the medium and long term. Today, the political situation in China remains stable - despite growing dissatisfaction in scientific expert and educational circles due to increased control over the intellectual sphere by the authorities. The need for a new redistribution of power between central and provincial authorities could potentially disrupt political stability in the medium term, but, at the moment, is not a critical negative factor. The economic situation is positive-stable. Forecasts indicate a possible increase in China's GDP in 2018 at 6.5%. At the same time, there are negative expectations in connection with the Sino-US and potentially Sino-European "trade war". In the Chinese foreign policy, as a response to Western pressure, China increasingly uses the Russian direction of its diplomacy in the expanded version of Russia + SCO. The nuance here is seen in China's adjusted approach to the SCO: first of all, not as a mechanism for cooperation with Russia, but as an organization that allows using Russia's potential for pressure on the US in the Sino-US strategic rivalry. In the second half of 2018, the Chinese economy will continue to develop steadily, albeit with unresolved traditional problems (debts of provinces and state-owned enterprises, ineffective state sector, risks on the financial and real estate market). In politics, discontent with the cult of Xi will accumulate, but without real threats to its power. Weakening in economic opposition between China and the United States is possible due to Beijing's search for compromises on tariffs, intellectual property, trade deficit. To find such trade-offs, Xi will use the so-called. "Personal diplomacy" of direct contacts with Trump.

• Journal of the Korean Society of Systems Engineering
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• v.13 no.2
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• pp.65-74
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• 2017

Supercritical carbon dioxide power system is the next generation electricity technology expected to be highly developed. The power system can improve net efficiency, simplify cycle configuration, and downsize equipment compared to conventional steam power system. In order to dominate the new market in advance, it is required to found Front End Engineering Design (FEED) Framework of the system. Therefore, this study developed the FEED framework including design processes for the supercritical carbon dioxide power system, information elements for each process, and relationships for each element. The developed FEED framework is expected to be able to secure systematic technological capabilities by establishing a common understanding and perspective among multi-field engineers participating in the design.

• Bulletin of the Korean Space Science Society
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• 2008.10a
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• pp.23.2-23.2
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• 2008

We presented the accurate absolute dimensions and distances of fifteen main sequence eclipsing binaries. The photometric and spectroscopic solutions of the binary systems were determined by analyzing light curves and radial velocity curves collected from the literature using the Wilson-Devinney computer code. The fifteen double-line spectroscopic binaries consist of nine detached systems; QX Car, AH Cep, CW Cep, ZZ Cep, XY Cet, RX Her, V451 Oph, VV Pyx and V760 Sco, six semi-detached systems; LY Aur, IU Aur, AO Cas, DM Per, V Pup and HU Tau. The temperatures of the binary systems were determined from their colors using the color-temperature calibrations. Then the temperature of each component star were determined using the temperature ratio which was adjusted from the light curves. We estimated the possible Z values and ages for the detached systems by adopting the Y2 (Yonsei-Yale) stellar evolutionary tracks. The derived distances are in good agreement of the Hipparcos distances whose error of parallax is within 10 %. Finally these well-investigated systems will be used as the standard eclipsing binaries.

• Journal of Microbiology and Biotechnology
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• v.18 no.7
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• pp.1216-1220
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• 2008

Sequence analysis of the metabolically rich genome of Streptomyces peucetius ATCC 27952 revealed a 2,199 bp sesquiterpene alcohol (germacradienol) synthase-encoding gene from the germacradienol synthase/terpene cyclase gene cluster. The gene was named spterp13, and its putative function is as a germacradienol synthase/terpene cyclase. The amino acid sequence of Spterp13 shows 66% identity with SAV2163 (GeoA) from S. avermitilis MA4680 and 65% identity with SCO6073 from S. coelicolor A3(2), which produces germacradienol/geosmin. The full-length recombinant protein was heterologously expressed as a his-tagged fusion protein in Escherichia coli, purified, and shown to catalyze the $Mg^{2+}$-dependent conversion of farnesyl diphosphate to the germacradienol, which was verified by gas chromatography/mass spectrometry.

• Journal of information and communication convergence engineering
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• v.2 no.2
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• pp.80-83
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• 2004

The core purpose of the system proposed in this paper is to help learners pursue proactive and self-oriented education by allowing learners to proactively configure their own content, that is, learners no longer have to be restricted by prescribed sequence of lectures. Although a variety of standardization and Learning Management System (LMS) were produced to develop and effectively manage web contents in response to active diffusion of internet application, practical changes to assist online learners are not yet to be found. In this paper, I would like to introduce a LMS that can support self-leading education by providing various types of learners at Virtual University with delicately organized educational contents for maximum efficiency. The system allows a learner to select a lecture or a chapter which has been presorted to meet his educational needs and intellectual ability. In general, most LMSs cannot meet every individual's educational needs because they structure their programs by letting learners simply choose from a list of available lectures at prescribed level or difficulty. However the Self-Leading LMS eliminates such boundaries by allowing learners to choose contents and difficulty within the limit set by their own educational competence.

• Publications of The Korean Astronomical Society
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• v.32 no.1
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• pp.101-103
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• 2017

We have carried out the near-infrared spectroscopic observations of recent classical novae (e.g., V2468Cyg, V1280Sco) within a few years from the outburst with AKARI as a part of AKARI Open Time Observing Program for Phase 3-II "Spectral Evolution of Novae in the Near-Infrared based on AKARI Observations (Proposal ID: SENNA)". The homogeneous datasets of near-infrared spectra from $2.5{\mu}m$ to $5{\mu}m$ with AKARI/IRC collected in this program are useful to infer the physical conditions of the shell formed by the ejected materials, to examine the chemical properties of the ejecta gas, and to examine the properties of dust formed in the nova ejecta.

• Proceedings of the Korean Institute of Building Construction Conference
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• 2008.11a
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• pp.49-52
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• 2008

The present study was to develop a dry PFB method similar to the existing gypsum board construction method in order to apply the existing wet PFB method that uses fire-resistant adhesive. It was found that the existing wet method can produce concrete compressive strength of 80MPa and fire resistance of 3 hours with 30mm PF boards. The goal of development in this study was fire resistance of 3 hours through dry construction of 15mm fire-resistant boards. 1. Improved PF board was prepared by adding inorganic fiber to existing board and using aggregate with grain size of 3mm or less. Molding was done at temperature higher than that for existing PF board molding. While wet curing is used for existing PF boards, this study used dry curing in order to enhance heat insulation performance. 2. According to the results of fire resistance test, when the dry PF method was applied, the temperature of the main reinforcing bar was 116℃ in 15mm, 103.8℃ in 20mm, and 94℃ in 25mm, and these results satisfied the current standards for fire resistance control presented by the Ministry of Land, Transport and Maritime Affairs. When a 3-hour fire resistance test was performed and the external properties of the specimen were examined, the outermost gypsum board hardly remained and internal PF board maintained its form without thermal strain.

• Biomolecules & Therapeutics
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• v.29 no.1
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• pp.98-103
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• 2021

The demand for natural substances with anti-melanogenic activity is increasing due to the recent interest in skin whitening. Intensive investigation on the culture broth of Streptomyces sp. SCO-736, a marine bacterium from the Antarctica coast, has led to the isolation of a new natural product named antaroide (1). The chemical structure was established through the interpretation of MS, UV, and NMR spectroscopic data. Antaroide is a nine-membered macrolide with lactone and lactam moieties. To investigate its applicability in skin whitening cosmetics, its anti-melanogenic activity in B16F10 murine melanoma cells was examined. As a result, antaroide displayed strong inhibitory activities against melanin synthesis and also attenuated the dendrite formation induced by the α-melanocyte stimulating hormone (α-MSH). Antaroide suppressed the mRNA expression of the melanogenic enzymes such as tyrosinase, TRP-1 and TRP-2. This suggests that it may serve as a transcriptional regulator of melanogenesis. Collectively, the discovery of this novel natural nine-membered macrolide and its anti-melanogenic activity could give new insights for the development of skin whitening agents.

• KSBB Journal
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• v.23 no.2
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• pp.153-157
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• 2008

Maca (Lepidium meyenii) has been used as a food and medicine in Peru for thousands of years. More recently a wide array of commercial maca products have gained popularity as dietary supplements with claims of anabolic and aphrodisiac effects. Even though the biologically active principles of maca are not fully known, the lipidic extract of maca tubers containing macamides showed promising physiological activities. In this study, the lipidic extract were collected from maca tubers by using supercritical carbon dioxide ($SCO_2$). Substance estimated as macamide in the extract was isolated and purified by preparative HPLC with recycling system. Two of the purified substance was identified as N-benzyl-5-oxo-6E,8E-octadecadienamide and N-benzylhexadecan amide by LC/MS, $^1H$-NMR and $^{13}C$-NMR analyses.

• Journal of Microbiology and Biotechnology
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• v.22 no.6
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• pp.736-741
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• 2012

In this study, we analyzed the oxidative stress response of wblA ($\underline{w}$hi$\underline{B}$-$\underline{l}$ike gene $\underline{A}$, SCO3579), which was previously shown to be a global antibiotic down-regulator in Streptomyces coelicolor. Ever since a WblA ortholog named WhcA in Corynebacterium glutamicum was found to play a negative role in the oxidative stress response, S. coelicolor wblA has been proposed to have a similar effect. A wblA-deletion mutant exhibited a less sensitive response to oxidative stress induced by diamide present in solid plate culture. Using real-time RT-PCR analysis, we also compared the transcription levels of oxidative stress-related genes, including sodF, sodF2, sodN, trxB, and trxB2, between S. coelicolor wild type and a wblA-deletion mutant in the presence or absence of oxidative stress. Target genes were expressed higher in the wblA-deletion mutant compared with wild type, both in the absence and presence of oxidative stress. Moreover, expression of these target genes in S. coelicolor wild type was stimulated only in the presence of oxidative stress, suggesting that WblA plays a negative role in the oxidative stress response of S. coelicolor, similar to that of C. glutamicum WhcA, through the transcriptional regulation of oxidative stress-related genes.