• Biomolecules & Therapeutics
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• 제19권3호
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• pp.315-319
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• 2011

Galanin (Gal) is a 29-amino-acid neuropeptide which is expressed in superior cervical ganglion (SCG) neurons and plays a trophic role in the adult animal and acts as an inhibitory modulator of cholinergic and noradrenergic neurotransmission. Whether activation or inhibition of alpha-adrenoreceptors infl uences Gal mRNA expression in SCG neurons remains unknown. Here, we have evaluated the possible regulation of Gal mRNA expression with acute (4 h) and chronic (4 days) stimulation of alpha 1- and alpha 2-adrenoreceptor agonists or antagonists in primary cultured SCG neurons. The results showed that the amount of Gal mRNA expression in cultured SCG neurons increased signifi cantly after chronic stimulation with alpha 2-adrenoreceptor antagonist yohimbine compared with control SCG neurons at the same time point, whereas the amount of Gal mRNA expression decreased signifi cantly after chronic stimulation with alpha 2-adrenoreceptor agonist clonidine as compared with that in control group. All these effects were not dose-dependent on the administration of alpha 2-adrenoreceptor agonist clonidine or alpha 2-adrenoreceptor antagonist yohimbine. Alpha 1-adrenoreceptor agonist phenylephrine or antagonist prazosin chronic stimulation did not have effects on Gal mRNA expression. Acute exposure of these agents did not have effects on Gal mRNA expression. The present study showed that Gal may be regulated by activation or inhibition of alpha 2-adrenoreceptors, but not alpha 1-adrenoreceptors in sympathetic neurons.

• Asian Pacific Journal of Cancer Prevention
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• 제13권3호
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• pp.781-784
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• 2012

The aim of this study was to evaluate the effect of the adenovirus-mediated double suicide gene (CD/TK) for selective killing of gastric cancer cells. Gastric cancer cells SCG7901 and normal gastric epithelial cell lines were infected by adenoviruses Ad-survivin/GFP and Ad-survivin/CD/TK. GFP expression and CD-TK were detected by fluorescence microscopy and reverse transcriptase polymerase chain reaction (RT-PCR), respectively. After treatment of the infected cells with the pro-drugs ganciclovir (GCV) and/or 5-FC, the cell growth status was evaluated by methyl thiazolyl tetrazolium assay. Cell cycle changes were detected using flow cytometry. In nude mice bearing human gastric cancer, the recombinant adenovirus vector was injected directly into the tumor followed by an intraperitoneal injection of GCV and/or 5-FC. The subsequent tumor growth was then observed. The GFP gene driven by survivin could be expressed within the gastric cancer line SCG7901, but not in normal gastric epithelial cells. RT-PCR demonstrated the presence of the CD/TK gene product in the infected SCG7901 cells, but not in the infected normal gastric epithelial cells. The infected gastric cancer SCG7901, but not the gastric cells, was highly sensitive to the pro-drugs. The CD/TK fusion gene system showed significantly greater efficiency than either of the single suicide genes in killing the target cells (P<0.01). Treatment of the infected cells with the pro-drugs resulted in increased cell percentage in G0-Gl phase and decreased percentage in S phase. In nude mice bearing SCG7901 cells, treatment with the double suicide gene system significantly inhibited tumor growth, showing much stronger effects than either of the single suicide genes (P<0.01). The adenovirus-mediated CD/TK double suicide gene driven by survivin promoter combined with GCV an 5-FC treatment could be an effective therapy against experimental gastric cancer with much greater efficacy than the single suicide gene CD/TK combined with GCV or 5-FC.

• 한국건설순환자원학회논문집
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• 제10권1호
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• pp.15-22
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• 2022

이 연구에서는 매년 대량으로 발생하는 커피찌꺼기를 건설소재로 재활용하기 위해 커피찌꺼기와 커피찌꺼기 애시를 혼입한 시멘트 모르타르의 수화반응성을 검토하고 강도 특성을 조사하였다. 연구 결과, 커피찌꺼기의 소성온도가 높아질수록 유기물의 연소로 인한 질량 손실은 커졌으나 밀도는 증가하는 것으로 나타났다. 또한 커피찌꺼기를 혼입했을 때는 시멘트 수화반응성이 저조하여 압축강도가 현저히 낮아졌다. 반면, 800 ℃에서 소성시킨 커피찌꺼기 애시는 수화반응이 원활하였으며, 압축강도는 OPC 모르타르와 동등한 수준으로 나타났다.

• 대한전기학회:학술대회논문집
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• 대한전기학회 2009년도 제40회 하계학술대회
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• pp.468_469
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• 2009

The application of renewable energy in electric power systems is growing rapidly in order to make provision for the inequality of the climate, the dwindling supplies of coal, oil and natural gas and a further rise in oil prices. Solar cell generators(SCG) is one of the fastest growing renewable energy. A study on the renewable energy is getting more important for the application of renewable energy. This paper presents the capacity factor of SCG by calculating the probabilistic production energy of SCG.

• 한국정보과학회:학술대회논문집
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• 한국정보과학회 2007년도 한국컴퓨터종합학술대회논문집 Vol.34 No.1 (D)
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• pp.389-394
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• 2007

SCG엔진 (Service Convergence Gateway Engine)은 UPnP와 웹 서비스간의 서비스를 변환해 주는 엔진이며, 동시에 홈 네트워크와 외부를 이어주는 게이트웨이이다. 홈 멀티미디어 통합 시스템을 구축하기 위해 홈 네트워크에서는 UPnP를 사용하고, 홈 네트워크에서 홈 네트워크 외부에서 미디어 컨텐츠를 사용하기 위해 웹 서비스를 사용하며, SCG엔진을 통해 UPnP와 웹 서비스 간의 서비스 변환을 하여 시스템을 구현해 보고자 한다. 본 논문에서는 SCG엔진을 사용한 홈 멀티미디어 통합 시스템을 설계 및 구현하여 홈 네트워크 내외의 미디어 컨텐츠를 통합하여 사용할 수 있도록 하는 방법에 대해 설명한다.

• 한국정보과학회:학술대회논문집
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• 한국정보과학회 2007년도 한국컴퓨터종합학술대회논문집 Vol.34 No.1 (D)
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• pp.537-540
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• 2007

분산된 서비스의 통합의 중요성이 커지고 있는 최근의 유비쿼터스 환경에서 SOA(Service Oriented Architecture)의 구현기술인 웹 서비스는 이러한 분산된 서비스를 연계하는 표준기술로서 기업내, 외부뿐만 아니라 방송/통신 융합, 정보가전/홈네트워크, 임베디드 환경 등 다양한 분야에서 사용되어 지고 있다. 본 논문에서는 홈네트워크에서 사용되는 디바이스등을 상호 이질적인 플랫폼이나 프로토콜에 유연하게 제공하기 위한 서비스 변환 게이트웨이 역할을 하는 SCG 엔진(Service Convergence Gateway Engine)과 서비스 연계의 표준기술로 자리잡고 있는 웹 서비스를 기반으로 SOA를 지원하고 S/W Service와 Application Component간의 연동을 위한 경량화된 Backbone의 역할을 수행하는 ESB(Enterprise Service Bus)를 사용하여 서비스를 통합하고 관리하는 구조를 제안 한다.

• 대한전기학회:학술대회논문집
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• 대한전기학회 1998년도 추계학술대회 논문집 학회본부A
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• pp.103-105
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• 1998

This paper presents the compensated 2-D magnetic fields analysis of superconducting AC generator(SCG) by using efficient 2-D model. 3-D analysis is necessary for the accurate analysis because SCG has a large leakage flux owing to the air cored winding and end ring structure. However, in 3-D FEM, considering the movement of rotor is difficult, so efficient 2-D model which can compensate the leakage flux has been proposed and the movement of rotor is easily considered. The characteristics in transient state of SCG and the prime role of damper also have been evaluated.

• 대한전기학회논문지
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• 제40권1호
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• pp.24-30
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• 1991

This paper deals with the analysis of the transient characteristics of a superconducting a.c. generator(SCG) using Finite Element Method. Since the magnetic field induced by the field current and the armature currents are not sinusoidally distributed in a generator, the conventional equivalent circuit method, in general, uses the fundamental component only and is done in frequency domain. But the finite element analysis makes it possible to analyze the transient magnetic field distribution and the electrical characteristics of the double shields of SCG in time domain.

• Journal of the Optical Society of Korea
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• 제18권3호
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• pp.207-216
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• 2014

In this work, we report detailed numerical analysis of the near-elliptic core index-guiding triangular-lattice and square-lattice photonic crystal fiber (PCFs); where we numerically characterize the birefringence, single mode, cut-off behavior and group velocity dispersion and effective area properties. By varying geometry and examining the modal field profile we find that for the same relative values of $d/{\Lambda}$, triangular-lattice PCFs show higher birefringence whereas the square-lattice PCFs show a wider range of single-mode operation. Square-lattice PCF was found to be endlessly single-mode for higher air-filling fraction ($d/{\Lambda}$). Dispersion comparison between the two structures reveal that we need smaller lengths of triangular-lattice PCF for dispersion compensation whereas PCFs with square-lattice with nearer relative dispersion slope (RDS) can better compensate the broadband dispersion. Square-lattice PCFs show zero dispersion wavelength (ZDW) red-shifted, making it preferable for mid-IR supercontinuum generation (SCG) with highly non-linear chalcogenide material. Square-lattice PCFs show higher dispersion slope that leads to compression of the broadband, thus accumulating more power in the pulse. On the other hand, triangular-lattice PCF with flat dispersion profile can generate broader SCG. Square-lattice PCF with low Group Velocity Dispersion (GVD) at the anomalous dispersion corresponds to higher dispersion length ($L_D$) and higher degree of solitonic interaction. The effective area of square-lattice PCF is always greater than its triangular-lattice counterpart making it better suited for high power applications. We have also performed a comparison of the dispersion properties of between the symmetric-core and asymmetric-core triangular-lattice PCF. While we need smaller length of symmetric-core PCF for dispersion compensation, broadband dispersion compensation can be performed with asymmetric-core PCF. Mid-Infrared (IR) SCG can be better performed with asymmetric core PCF with compressed and high power pulse, while wider range of SCG can be performed with symmetric core PCF. Thus, this study will be extremely useful for designing/realizing fiber towards a custom application around these characteristics.

• 한국균학회지
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• 제40권4호
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• pp.292-295
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• 2012

구름버섯은 온대지역에서 흔히 발견되는 목재 부후균으로서 중요한 약용버섯의 일종이다. 본 연구에서는 커피박, 과립커피 및 과립 디카페인 커피의 구름버섯 균사체 생장에 미치는 영향을 조사하였다. 그 결과, 커피박은 10% 농도에서까지 그리고 과립커피의 경우 1% 미만에서 균사체 생육을 촉진시키는 것으로 확인되었다. 1% 커피박의 경우 무처리에 비해 10배 정도의 건조중량 증가가 측정됨으로써 구름균사체의 생육촉진제로서의 커피 효능을 확인할 수 있었다. 또한 커피는 균사체의 페놀화합물 및 항산화 효능 증대를 위한 유용 물질로 판단되었다.