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Distributed Social Medical IoT for Monitoring Healthcare and Future Pandemics in Smart Cities

  • Mansoor Alghamdi;Sami Mnasri;Malek Alrashidi;Wajih Abdallah;Thierry Val
    • International Journal of Computer Science & Network Security
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    • v.24 no.5
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    • pp.135-155
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    • 2024
  • Urban public health monitoring in smart cities focuses on the control of conditions and health challenges in urban environments. Considering the rapid spread of diseases and pandemics, it is important for health authorities to trace people carrying the virus. In smart cities, this tracing must be interoperable and intelligent, especially in indoor surfaces characterized by small distances between people. Therefore, to fight pandemics, it is necessary to start with the already-existing digital equipment of the Internet of Things, such as connected objects and smartphones. In this study, the developed system is employed to provide a social IoT network and suggest a strategy which allows reliable traceability without threatening the privacy of users. This IoT-based system allows respecting the social distance between persons sharing public services in smart cities without applying smartphone applications or severe confinement. It also permits a return to normal life in case of viral pandemic and ensures the much-desired balance between economy and health. The present study analyses previous proposed social distance systems then, unlike these studies, suggests an intelligent and distributed IoT based strategy for positioning students. Two scenarios of static and dynamic optimization-based placement of Bluetooth Low Energy devices are proposed and an experimental study shows the contribution and complementarity of the introduced contact tracing strategy with the applications on smartphones.

Human Papillomavirus Genotype Distribution and E6/E7 Oncogene Expression in Turkish Women with Cervical Cytological Findings

  • Tezcan, Seda;Ozgur, Didem;Ulger, Mahmut;Aslan, Gonul;Gurses, Iclal;Serin, Mehmet Sami;Giray, Burcu Gurer;Dilek, Saffet;Emekdas, Gurol
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.9
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    • pp.3997-4003
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    • 2014
  • Background: Infection with certain human papillomavirus (HPV) genotypes is the most important risk factor related with cervical cancer. The objective of the present study was to investigate the prevalence of HPV infection, the distribution of HPV genotypes and HPV E6/E7 oncogene mRNA expression in Turkish women with different cervical cytological findings in Mersin province, Southern Turkey. Materials and Methods: A total of 476 cytological samples belonging to women with normal and abnormal cervical Pap smears were enrolled in the study. For the detection and genotyping assay, a PCR/direct cycle sequencing approach was used. E6/E7 mRNA expression of HPV-16, 18, 31, 33, and 45 was determined by type-specific real-time NASBA assay (NucliSENS EasyQ$^{(R)}$HPV v1.1). Results: Of the 476 samples, 106 (22.3%) were found to be positive for HPV DNA by PCR. The presence of HPV was significantly more common (p<0.001) in HSIL (6/8, 75%) when compared with LSIL (6/14, 42.9%), ASC-US (22/74, 29.7%) and normal cytology (72/380, 18.9%). The most prevalent genotypes were, in descending order of frequency, HPV genotype 66 (22.6%), 16 (20.8%), 6 (14.2%), 31 (11.3%), 53 (5.7%), and 83 (4.7%). HPV E6/E7 oncogene mRNA positivity (12/476, 2.5%) was lower than DNA positivity (38/476, 7.9%). Conclusions: Our data present a wide distribution of HPV genotypes in the analyzed population. HPV genotypes 66, 16, 6, 31, 53 and 83 were the predominant types and most of them were potential carcinogenic types. Because of the differences between HPV E6/E7 mRNA and DNA positivity, further studies are required to test the role of mRNA testing in the triage of women with abnormal cervical cytology or follow up of HPV DNA positive and cytology negative. These epidemiological data will be important to determine the future impact of vaccination on HPV infected women in our region.

Slope Failure Prediction through the Analysis of Surface Ground Deformation on Field Model Experiment (현장모형실험 기반 표층거동분석을 통한 사면붕괴 예측)

  • Park, Sung-Yong;Min, Yeon-Sik;Kang, Min-seo;Jung, Hee-Don;Sami, Ghazali-Flimban;Kim, Yong-Seong
    • Journal of the Korean Geosynthetics Society
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    • v.16 no.3
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    • pp.1-10
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    • 2017
  • Recently, one of the natural disasters, landslide is causing huge damage to people and properties. In order to minimize the damage caused by continuous landslide, a scientific management system is needed for technologies related to measurement and monitoring system. This study aims to establish a management system for landslide damage by prediction of slope failure. Ground behavior was predicted by surface ground deformation in case of slope failure, and the change in ground displacement was observed as slope surface. As a result, during the slope failure, the ground deformation has the collapse section, the after collapse precursor section, the acceleration section and the burst acceleration section. In all cases, increase in displacement with time was observed as a slope failure, and it is very important event of measurement and maintenance of risky slope. In the future, it can be used as basic data of slope management standard through continuous research. And it can contribute to reduction of landslide damage and activation of measurement industry.

A Study on Hybrid Grout Material for Reservoir Embankment reinforcement (저수지 제방 보수보강을 위한 하이브리드형 그라우트재 연구)

  • Park, Sung-Yong;Shim, Houng-Gen;Kang, Hee-Jin;Lim, One-Bin;Sami, Ghazali-Flimban;Kim, Yong-Seong
    • Journal of the Korean Geosynthetics Society
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    • v.16 no.3
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    • pp.21-30
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    • 2017
  • Cement grouting method is generally applied for the purpose of reinforcement of deteriorated reservior. Problems have been raised due to the limit of the injection material. In order to solve these problems, various grout materials have been developed. However, there are many cases in which the grounds are disturbed in actual field. In this study, the physical properties of hybrid grout with high fineness and high viscosity characteristics were analyzed to enable penetration into the ground. Optimum inflation agent was selected and mixed with the grout. The pressure and compaction effect on expansion was examined and its effectiveness was verified. From the result of confirming expansion ratio, uniaxial compressive strength, expansion pressure and compaction effect, the HI-E (2%) sample was analyzed to be excellent in improvement effect by the inflation agent. Hence, hybrid grout can be effectively applied for the impermeable and reinforcement method of deterioration reservoir and tide embankment.

Risk of Breast Cancer among Young Women and Importance of Early Screening

  • Memon, Zahid Ali;Kanwal, Noureen;Sami, Munam;Larik, Parsa Azam;Farooq, Mohammad Zain
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.17
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    • pp.7485-7489
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    • 2015
  • Background: Breast cancer is the most common type of cancer in women throughout the world. However, in comparison with Western women, it presents relatively early in women of Asian ethnicity. Early menarche, late menopause, use of OCP's, family history of benign or malignant breast disease, exposure to radiation and BMI in the under-weight range are well known risk factors for the development of breast cancer in premenopausal women. Early detection with the use of breast self-examination (BSE) and breast cancer screening programs can lead to a reduction in the mortality rates due to breast cancer. The aim of our study was to assess the risk factors for breast cancer among young women and to emphasize the importance of early screening among them. Materials and Methods: We conducted a cross-sectional study among women aged 18 to 25 using a self-administered questionnaire. Data was collected over a period of 6 months from June to December, 2014. A total of 300 young women selected randomly from Dow Medical College and various departments of Karachi University successfully completed the survey. Results: Respondents were 18-25 years of age (mean age=21.5). Out of the 300 young females, 90 (30%) had at least one risk factor, 90 (30%) had two, 40 (13%) had three, 8 (2.7%) had four, 2 (0.7%) had five while one female was found to have six positive risk factors for breast cancer. Some 66 women (22%) experienced symptoms of breast cancer such as non-cyclical pain and lumps. While 222 women (74%) had never performed breast self-examination, 22 (7.3%) had had a breast examination done by a health professional while 32 (10.7%) had participated in breast screening programs. A total of 223 (74.3%) women considered breast cancer screening important for young women. Conclusions: The percentage of young women with risk factors for breast cancer was found to be alarmingly high. Therefore, screening for breast cancer should start at an early age especially in high risk groups. Awareness about breast self-examination should be emphasized. Moreover, screening programs should be started to ensure early detection and reduction of mortality rates caused by breast cancer also in young Pakistani females.

Properties of Permeable Block using Artificial Permeable Pipe and Polymer Powder VAE to Improve Permeability (투수성을 개선시키기 위해 인공투수관 및 분말형 폴리머 VAE를 사용한 투수블록의 특성)

  • Yoo, Beong-Young;Lee, Won-Gyu;Pyeon, Su-Jeong;Kim, Dea-Yeon;Lee, Sang-Soo
    • Journal of the Korea Institute of Building Construction
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    • v.18 no.5
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    • pp.447-453
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    • 2018
  • Since 1960, Korea the town center was developed intensively due to rapid industrial development. As a result of the development, the population was concentrated in urban areas and the green area was decreased. Due to the decrease of the green area, the circulation system of the rainwater was changed, hence the rainwater was not introduced into the groundwater., On the other hand, the water on the surface of the road was changed into the water for flowing to the river and evaporation. The changes in the water flow cause many problems, and the depletion of the groundwater does not create an environment in which microorganisms and plants can live. in Korea, permeable pavement construction is increased to solve these problems, but existing pavement blocks have many problems. The pores of the permeable block are clogged due to the accumulation of dust or whitening phenomenon, and the permeability is lost. In this study, the solution of the problems of existing permeable block were suggested by using polymer and artificial permeable pipe, and strength, permeability and service life are increased, The relationship between the substitution rate of the polymer and the mixing ratio of the artificial permeable pipe was analyzed.

Appearance Patterns of Freshwater Fish in Western DMZ Adjacent Areas, Gyeonggi-do, Korea (서부 DMZ 인접지역의 담수어류 출현양상)

  • Ko, Myeong-Hun;Ko, Jae Geun;Kim, Hyeong Su
    • Korean Journal of Ecology and Environment
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    • v.48 no.1
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    • pp.38-50
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    • 2015
  • Appearance patterns of freshwater fish were investigated in the western Demilitarized Zone (DMZ) adjacent areas near Imjin River in Gyeonggi-do, Korea, of 2014. A total of 61 species belonging to 14 families were found in the river during the survey. The dominant and subdominant species were Zacco platypus (Relative abundance, 20.3%) and Zacco koreanus (12.6%), respectively. Other abundant species include Rhinogobius brunneus (9.2%), Pungtungia herzi (4.4%), Acheilognathus yamatsutae (4.4%), and Pseudogobio esocinus (4.0%). Among the residing species, 24 species (39.3%) were endemic to Korea; and 1 species, Carassius cuvieri, was non-indigenous species. Hemibarbus mylodon is a natural monument, and Lethenteron reissneri, Acheilognathus signifer, Pseudopungtungia tenuicorpa, Gobiobotia brevibarba, G. macrocephala, and G. naktongensis are endangered species in Korea. In addition, Anguilla japonica and Plecoglossus altivelis are catadromous and amphidromous species, respectively. Among the investigated sites, the lower part of Sami Stream (St. 5, 6) and Gunnarm-dam region (St. 11, 14) are particularly valuable for the conservation of species diversity, because many fish species (33~42 species) including a natural monument and several endangered species inhabit in these regions.

Comprehensive investigations of key mitochondrial metabolic changes in senescent human fibroblasts

  • Ghneim, Hazem K.;Alfhili, Mohammad A.;Alharbi, Sami O.;Alhusayni, Shady M.;Abudawood, Manal;Aljaser, Feda S.;Al-Sheikh, Yazeed A.
    • The Korean Journal of Physiology and Pharmacology
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    • v.26 no.4
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    • pp.263-275
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    • 2022
  • There is a paucity of detailed data related to the effect of senescence on the mitochondrial antioxidant capacity and redox state of senescent human cells. Activities of TCA cycle enzymes, respiratory chain complexes, hydrogen peroxide (H2O2), superoxide anions (SA), lipid peroxides (LPO), protein carbonyl content (PCC), thioredoxin reductase 2 (TrxR2), superoxide dismutase 2 (SOD2), glutathione peroxidase 1 (GPx1), glutathione reductase (GR), reduced glutathione (GSH), and oxidized glutathione (GSSG), along with levels of nicotinamide cofactors and ATP content were measured in young and senescent human foreskin fibroblasts. Primary and senescent cultures were biochemically identified by monitoring the augmented cellular activities of key glycolytic enzymes including phosphofructokinase, lactate dehydrogenase, and glycogen phosphorylase, and accumulation of H2O2, SA, LPO, PCC, and GSSG. Citrate synthase, aconitase, α-ketoglutarate dehydrogenase, succinate dehydrogenase, malate dehydrogenase, isocitrate dehydrogenase, and complex I-III, II-III, and IV activities were significantly diminished in P25 and P35 cells compared to P5 cells. This was accompanied by significant accumulation of mitochondrial H2O2, SA, LPO, and PCC, along with increased transcriptional and enzymatic activities of TrxR2, SOD2, GPx1, and GR. Notably, the GSH/GSSG ratio was significantly reduced whereas NAD+/NADH and NADP+/NADPH ratios were significantly elevated. Metabolic exhaustion was also evident in senescent cells underscored by the severely diminished ATP/ADP ratio. Profound oxidative stress may contribute, at least in part, to senescence pointing at a potential protective role of antioxidants in aging-associated disease.