• 제목/요약/키워드: SAGE

검색결과 245건 처리시간 0.036초

Quantitative Analysis of Nucleic Acids - the Last Few Years of Progress

  • Ding, Chunming;Cantor, Charles R.
    • BMB Reports
    • /
    • 제37권1호
    • /
    • pp.1-10
    • /
    • 2004
  • DNA and RNA quantifications are widely used in biological and biomedical research. In the last ten years, many technologies have been developed to enable automated and high-throughput analyses. In this review, we first give a brief overview of how DNA and RNA quantifications are carried out. Then, five technologies (microarrays, SAGE, differential display, real time PCR and real competitive PCR) are introduced, with an emphasis on how these technologies can be applied and what their limitations are. The technologies are also evaluated in terms of a few key aspects of nucleic acids quantification such as accuracy, sensitivity, specificity, cost and throughput.

초고해상도 디스플레이를 위한 비압축 HD 가시화 서비스 구현 (Implementation of Uncompressed HD Video Visualization Service for Ultra High Resolution Display)

  • 최기호;;김종원
    • 한국HCI학회:학술대회논문집
    • /
    • 한국HCI학회 2007년도 학술대회 1부
    • /
    • pp.713-718
    • /
    • 2007
  • 본 논문에서는 실시간적인 요소와 높은 경험의 질을 요구하는 다자간 협업 환경에서 고해상도 비디오를 제공하기 위하여, 무손실과 저지연, 저비용의 특징을 갖는 비압축 HD 비디오를 처리할 수 있는 '비압축 HD 비디오 전송 응용' (Scalable Video Tool)을 구현하여 초고해상도 디스플레이를 위한 비압축 HD 가시화 서비스'를 구성한다. Scalable Video Tool (SVT)은 Microsoft 사의 Direct Show를 기반으로, 비압축 HD 카메라와 DV 카메라, WebCam의 영상도 실시간으로 처리가 가능하다. 초고해상도 디스플레이에 고해상도 비디오와 이미지 가시화를 지원하는 SAGE(Scalable adaptive graphics environment)[2]와 SVT를 연동하여 다자간 협업 환경에서 다양한 형태의 고해상도 비디오와 그래픽스 자료를 공유할 수 있는 시스템을 구성한다. 본 논문의 마지막에서는 $5{\times}11$의 격자 형태로 구성된 타일드 디스플레이 (Tiled Display)를 이용하여 제안된 시스템을 검증한다.

  • PDF

A New Approach for SINS Stationary Self-alignment Based on IMU Measurement

  • Zhou, Jiangbin;Yuan, Jianping;Yue, Xiaokui
    • 한국항해항만학회:학술대회논문집
    • /
    • 한국항해항만학회 2006년도 International Symposium on GPS/GNSS Vol.1
    • /
    • pp.355-359
    • /
    • 2006
  • For the poor observability of azimuth misalignment angle and east gyro drift rate of the traditional initial alignment, a bran-new SINS stationary fast self-alignment approach is proposed. By means of analyzing the characteristic of the strapdown inertial navigation system (SINS) stationary alignment seriously, the new approach takes full advantage of the specific force and angular velocity information given by inertial measurement unit (IMU) instead of the mechanization of SINS. Firstly, coarse alignment algorithm is presented. Secondly, a new fine alignment model for SINS stationary self-alignment is derived, and the observability of the model is analysed. Then, a modified Sage-Husa adaptive Kalman filter is introduced to estimate the misalignment angles. Finally, some computer simulation results illustrate the efficiency of the new approach and its advantages, such as higher alignment accuracy, shorter alignment time, more self-contained and less calculation.

  • PDF

RAW 264.7 Cell에서 세이지에 의한 염증성 Cytokine 및 iNOS억제 효과 (Inhibitory Effect of Salvia officinalis on the Inflammatory Cytokines and Inducible Nitric Oxide Synthasis in Murine Macrophage RAW264.7)

  • 현은아;이혜자;윤원종;박수영;강희경;김세재;유은숙
    • 약학회지
    • /
    • 제48권2호
    • /
    • pp.159-164
    • /
    • 2004
  • Primary pro-inflammatory cytokines are a trio: tumor necrosis- $\alpha$ (TNF-$\alpha$), interleukine-$\beta$ (IL-$\beta$), and interleukine-6 (IL-6). These cytokines initiate and regulate the acute-phase inflammatory response during infection, trauma, or stress and appear to play an important role in the immune process. Nitric oxide (NO) is a multi-functional mediator, which plays an important role in regulating various biological functions in vivo. NO production by inducible nitric oxide synthase (iNOS) in macrophages is essential for the defense mechanisms against microorganisms and tumor cells. However, over-expression of iNOS by various stimuli, resulting in over-production of NO, contributes to the pathogenesis of septic shock and some inflammatory and auto-immune disease. Solvent fractions of sage ( Salvia officinalis L.), which is cultivated in Jeju-Do, was assayed for their effects on TNF-$\alpha$ and IL-6 production in LPS-stimulated RAW 264.7 macrophages. Hexane and ethylacetate (EtOAc) fraction of sage inhibited the protein and mRNA expression of TNF-$\alpha$ and IL-6 in LPS stimulated RAW 264.7 cells at the concentration of 100 $\mu\textrm{g}$/$m\ell$. Also, incubation of RAW 264.7 cells with the fraction of hexane or EtOAc (50 $\mu\textrm{g}$/$m\ell$) inhibited the LPS induced nitrite accumulation and the LPS/IFN-${\gamma}$ induced iNOS protein. And this inhibition of iNOS protein is concordant with the inhibition of iNOS mRNA expression. Above results suggest that extract of sage may have anti-inflammatory activity through the inhibition of pro-inflammatory cytokines (TNF-$\alpha$, IL-1$\beta$, IL-6), iNOS and NO.

The Surgical Impact of E-Cigarettes: A Case Report and Review of the Current Literature

  • Fracol, Megan;Dorfman, Robert;Janes, Lindsay;Kulkarni, Swati;Bethke, Kevin;Hansen, Nora;Kim, John
    • Archives of Plastic Surgery
    • /
    • 제44권6호
    • /
    • pp.477-481
    • /
    • 2017
  • We report a case of a 51 years old female with a 25 pack year smoking history who underwent bilateral mastectomy and immediate tissue expander reconstruction for newly diagnosed right breast cancer. The patient reported herself as a non-smoker despite significant e-cigarette use, with resulting significant mastectomy skin flap necrosis and breast reconstruction failure. Little is known about the physiologic effect of e-cigarettes on wound healing and tissue perfusion. To this end, we provide an updated review of the impact of e-cigarettes on surgical outcomes. PubMed, Ovid MEDLINE, and PRS GO were searched for the terms "e-cigarette", "electronic cigarette", "e-cig", "electronic nicotine delivery system", "vaping", "surgery", "surgical", "peri-operative", "operate", "operative", and "wound healing". Abstract review of all articles was performed. 123 articles returned that contained both variants of e-cigarettes and surgery as keywords. Of those, manual assessment returned three articles which were found to be relevant to e-cigarette use in the surgical patient. No articles were found that compared perioperative complications in e-cigarette versus traditional cigarette users in humans. In conclusion, our case report depicts the potential dangers associated with e-cigarette use in the surgical patient. There is a public misconception that e-cigarettes are healthier than traditional cigarettes and as such their use may go unreported by patients. Early evidence suggests e-cigarettes may induce some of the same physiologic changes as traditional cigarettes, and may have a significant deleterious effect on wound healing.

Analysis of Tropical Tropospheric Ozone Derivation from Residual-Type Method

  • Na Sun-Mi;Kim Jae-Hwan
    • 대한원격탐사학회지
    • /
    • 제22권1호
    • /
    • pp.1-10
    • /
    • 2006
  • During the northern burning season, biomass burning is found north of the equator, while satellite estimates from the residual-type method such as the CCD method show higher ozone south of the equator. This discrepancy is called the tropical Atlantic paradox (Thompson et ai., 2000). We use satellite and ground-based measurements to investigate the paradox. When the background tropospheric ozone over the Pacific Ocean from TOMS measurements is subtracted from the latitudinal total ozone distribution (e.g. TOMS-Pacific method), the results show remarkable agreement with the latitudinal stratospheric ozone distribution using the CCD method. The latitudinal tropospheric ozone distribution using the CCD method, with a persistent maximum over the southern tropical Atlantic, is also seen in the latitudinal tropospheric ozone distribution using the TOMS-Pacific method. It suggests that the complicated CCD method can be replaced by the simple TOMS-Pacific method. However, the tropical Atlantic paradox exists in the results of both the CCD and TOMS-Pacific methods during the northern buming season. In order to investigate this paradox, we compare the latitudinal ozone distributions using the CCD and TOMS-Pacific methods by using the SAGE measurements (e.g. TOMS-SAGE method) and the SHADOZ ozonesoundings (e.g. TOMS-Sonde method) assuming zonally invariant stratospheric ozone, which is the same assumption as of the CCD method. During the northern burning season, the latitudinal distributions in the tropospheric ozone derived from the TOMS-SAGE and TOMS-Sonde methods show higher tropospheric ozone over the northern tropical Atlantic than the southern Atlantic due to a stronger gradient in stratospheric ozone relative to that from the CCD and TOMS-Pacific methods. This indicates that the latitudinal tropospheric ozone distribution can be changed depending on the data that is used to determine the latitudinal stratospheric ozone distribution. Therefore, there is a possibility that the north-south gradient in stratospheric ozone over the Atlantic can be a solution of the paradox.

인공광 식물공장내 광질 제어가 작물생육에 미치는 영향 (Effects of Light-Quality Control on the Plant Growth in a Plant Factory System of Artificial Light Type)

  • 허정욱;백정현
    • 한국환경농학회지
    • /
    • 제40권4호
    • /
    • pp.270-278
    • /
    • 2021
  • BACKGROUND: Horticultural plant growth under field and/or greenhouse conditions is affected by the climate changes (e.g., temperature, humidity, and rainfall). Therefore investigation of hydroponics on field horticultural crops is necessary for year-round production of the plants regardless of external environment changes under plant factory system with artificial light sources. METHODS AND RESULTS: Common sage (Salvia plebeia), nasturtium (Tropaeolum majus), and hooker chive (Allium hookeri) plants were hydroponically culturing in the plant factory with blue-red-white LEDs (Light-Emitting Diodes) and fluorescent lights (FLs). Leaf numbers of common sage under mixture LED and FL treatments were 134% and 98% greater, respectively than those in the greenhouse condition. In hooker chives, unfolded leaf numbers were 35% greater under the artificial lights and leaf elongation was inhibited by the conventional sunlight compared to the artificial light treatments. Absorption pattern of NO3-N composition in hydroponic solution was not affected by the different light qualities. CONCLUSION(S): Plant factory system with different light qualities could be applied for fresh-leaf production of common sage, nasturtium, and hooker chive plants culturing under field and/or greenhouse. Controlled light qualities in the system resulted in significantly higher hydroponic growth of the plants comparing to conventional greenhouse condition in present.