• 한국원자력학회:학술대회논문집
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• 한국원자력학회 1998년도 추계학술발표회요약집
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• pp.362-362
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• 1998

• Journal of Microbiology and Biotechnology
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• 제20권6호
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• pp.1022-1026
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• 2010

The different cleavage patterns of pYBamy59 plasmid isolated from E. coli $DH5{\alpha}$ and B. longum MG1 by the cell extract of B. longum MG1 suggested that the main reason for its low transformation efficiency was related to the restriction modification (R-M) system. To confirm the correlation between the R-M system and transformation efficiency, in vitro methylation and site-directed mutagenesis were performed in pYBamy59. Sequence analysis of pYBamy59 fragments digested by the cell extract of B. longum MG1 revealed that all fragments were generated by restriction of the sequence recognized by SacII endonuclease. When pYBamy59 from E. coli was methylated in vitro by CpG or GpC methyltransferase, it was protected from SacII digestion. Site-directed mutagenesis, which removed SacII sites from pYBamy59, or in vitro methylation of pYBamy59 showed 8- to 15-fold increases in the transformation efficiency over intact pYBamy59. Modification of the SacII-related R-M system in B. longum MG1 and in vitro methylation in pYBamy 59 can improve the transformation efficiency in this strain. The results showed that the R-M system is a factor to limit introduction of exogenous DNA, and in vitro modification is a convenient method to overcome the barrier of the R-M system for transformation.

• Archives of Plastic Surgery
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• 제35권2호
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• pp.197-200
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• 2008

Purpose: A congenital lacrimal sac fistula is unusual and consists of a dimple opening below the medial canthal tendon that leads to the lacrimal sac. This anlage ducts occur when the lacrimal anlage cells proliferate and canalize rather than involute. And, the anomaly is usually not associated with any systemic abnormalities. Also congenital cleft of the earlobes is rarely seen among congenital ear anomalies. Therefore, we report rare case with symptomatic bilateral lacrimal fistula with the ear cleft. Methods: A 4-year-old boy was admitted with aggravated chronic maxillary sinusitis, recurrent chronic dacryocystitis, and epiphora. He had two minor anomalies including bilateral lacrimal fistula originated in lacrimal tear sac and unilateral transverse ear cleft. The patient had been operated with fistulectomy and perioperative antibiotics. A small vertical ellipse is made around the opening with sharp dissection. The tract is excised using the probe as the guide. Another probe is placed through the lower canaliculus to prevent the damage. A suture ligature of 6-0 Maxon is placed around the deepest point of the tract, which is then excised. Additional sutures are placed in the tissues to form a tight closure to prevent reestablishment of the fistula. The skin is closed with 6-0 Black Silk. Results: The patient recovered well without any complications such as infection, epiphora, and obstruction of lacrimal sac. Conclusion: Our case illustrates bilateral lacrimal anlage ducts in a patient with unilateral congenital ear cleft. We recommend careful evaluation of lacrimal system in these patients, especially bilateral case and other congenital anomalies. Finally, we recommend excision of the ducts when epiphora, infection, or chronic skin irritation occur.

• 한국통신학회논문지
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• 제30권6C호
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• pp.465-474
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• 2005

본 논문은 잡음이 존재하는 전송 선로를 통해 전송된 영상의 손실 블록에 대해 방향성 복구 방법을 제안한다. 손실된 DCT 계수나 화소값들은 손실된 블록 주위의 마주보는 블록 간 DC값 차이(DDC:Difference of DC)와 AC계수의 유사성(SAC: Similarity of AC)으로 구성된 방향성 척도에 의해 적응적으로 선택되어진 이웃 블록들을 이용해서 선형 보간법으로 복구된다. 본 논문에서 제안하는 방향성 복구 방법은 고정된 이웃 블록을 이용하지 않고 국부 영상 내의 방향성 정보에 따라 적응적으로 변하는 이웃 블록들이 사용하기 때문에 강한 에지 성분이나 텍스쳐 영역에 대해서 효과적이다. 본 논문에서는 DDC와 SAC로 구성된 새로운 방향성 척도(CDS: Combination of DDC and SAC)를 구하고 그 방향성 척도를 통해 국부 영역의 특성에 따라 손실된 블록을 복구하기 위한 블록들을 선택한다. 모의실험에서 제안 방법은 기존의 방법보다 평균적으로 약 0.6dB의 PSNR 개선을 보였다.

• 대한의용생체공학회:의공학회지
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• 제22권6호
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• pp.551-557
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• 2001

크맆현상에 따른 척추경막의 교합 원인과 교합량을 유한요소 모델을 이용하여 정량적으로 구하였다. 교합량은 척추경막의 단면적 변화로 나타내었다. 500 N부터 6000 N가지 수직 방향으로의 축하중과 2 Nm에서 10 Nm 가지의 굴전. 신전 모멘트 변화에 따른 척추경막의 교합량을 구한 결과 2000 N이상에서의 하중에서만 척추경막의 교합이 발생하였다. 신전을 동반한 수직압축의 경우 교합량이 단순 압축에 비해 더 크게 나타났다. 2 kN의 압축력이 8 Nm의 신전 모멘트와 함께 작용되었을 경우 7.4%. 10 Nm의 모멘트와 함께 작용하였을 경우에는 10.5%의 교합량이 발생했다 크릴에 따른 교합량의 변화는 신전시 가장 크게 나타났으며 10 Nm의 모멘트가 작용될 경우에서 6.7%의 교합량과 2.4%의 체적 감소가 계산되었다. 교합현상은 주로 황색인대의 이완과 추간판의 팽륜에 의해 발생되었으며 신전시에는 황색인대가 교합의 주원인이 되었다. 굴전으로 인한 교합현상은 발생되지 않았다.

• Journal of Welding and Joining
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• 제26권5호
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• pp.43-48
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• 2008

Characteristics of Sn-1.7%Bi-0.7%Cu-0.6%In (hereafter, SBIC) lead-free solder was investigated in this study. The results from SBIC were compared to other lead-free solders such as Sn-3.5%Ag-0.7%Cu (hereafter, SAC), Sn-0.7%Cu (hereafter, SC), and lead-bearing Sn-37%Pb (hereafter, SP) alloy. Tensile properties of bulk solder, wettability, spreading index, bridge and dross were evaluated. As experimental results, tensile strength and elongation of SBIC was 62.5MPa and 21.5%, respectively. The tensile strength was comparable to that of SP solder. The wetting time of SBIC was 1.2 sec at $250^{\circ}C$, and its wetting properties including wetting force were as good as the SAC alloy. However, wettability of the SC was not so good as the SBIC and SAC. The spreading index of SBIC at $250^{\circ}C$ was 71 %, and it was similar level to those of SAC and SC solders. Bridging was not found for all solders of SBIC, SAC and SC in the range from 240 to $260^{\circ}C$. In dross test at $250^{\circ}C$ for an hour, the amount of dross produced from SBIC was about 57% compared to that from SAC.

• 대한금속재료학회지
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• 제47권8호
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• pp.500-507
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• 2009

Pb-free solder has recently been used in electronics in efforts to meet environmental regulations, and a number of Pb-free solder alloy choices beyond the near-eutectic SnAgCu solder are now available. With increased demand for thin and portable electronics, the high cost of alloys containing significant amounts of silver and their poor mechanical shock performance have spurred the development of low Ag SnAgCu solder, which provides improved mechanical performance at a reasonable cost. Although low Ag SnAgCu solder exhibits significantly higher fracture resistance under high-strain rates, little thermal fatigue data exist for this solder. Therefore, it is necessary to investigate thermal fatigue reliability of low Ag SnAgCu solder under variation of thermal stress in order to allow its implementation in electronic products with high reliability requirements. In this study, the reliability of Sn0.3Ag0.7Cu(SAC0307), a low Ag solder alloy, is discussed and compared with that of Sn3Ag0.5Cu(SAC305). Three sample types and six samples size are evaluated. Mechanical properties and microstructure of the solder joint are investigated under thermal shock cycles. It was observed that the mechanical strength of SAC0307 dropped slightly with thermal cycling relative to that of SAC305. This reveals that the failure mode of SAC0307 is different from that SAC305 under this critical condition.

• 정보보호학회논문지
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• 제11권4호
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• pp.67-75
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• 2001

비동기식(W-CDMA) 3세대 이동통신의 3GPP는 무선 구간에서의 데이터 기밀성과 무결성을 제공하기 위하여 블록 암호 KASUMI에 기반한 f8과 f9 알고리즘을 제안했다. 또한, 3GPP 인증 및 키 생성 함수들에 대한 예로써 블록 암호 Rijndael에 기반한 Milenage 알고리즘을 제안했다. 따라서 3GPP 알고리즘의 안전성을 분석하기 위해서는 핵심 알고리즘인 KASUMI와 Rijndael의 안전성 분석이 선행되어야 한다. 블록 암호의 여러 구성 요소들 중에서 S-box는 가장 기본적인 안전성 요인들이 함축된 함수로 볼 수 있으므로 본 논문에서 우리는 KASUMI와 Rijndael의 S-box를 비교 분석한다. 더욱이 KASUMI S9-box의 AC 및 SAC특성이 좋지 않지만, S7-box와 S9-box를 포함하고 있는 KASUMI FI 함수의 AC는 Rijndael S-box의 AC와 같고, KASUMI FI 함수의 SAC은 Rijndael S-box의 SAC과 비교해 좋다는 사실을 규명한다.

• Journal of Korean Neurosurgical Society
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• 제67권1호
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• pp.42-49
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• 2024

Objective : There is still controversy regarding whether neck remodeling stent affects the occurrence of silent embolic infarction (SEI) after aneurysm coiling. Thus, the aim of the present study is to investigate the incidence of SEI after stent-assisted coiling (SAC) using Neuroform Atlas Stent (NAS) and possible risk factors. This study also includes a comparison with simple coiling group during the same period to estimate the impact of NAS on the occurrence of SEI. Methods : This study included a total of 96 unruptured intracranial aneurysms in 96 patients treated with SAC using NAS. Correlations of demographic data, aneurysm characteristics, and angiographic parameters with properties of SEI were analyzed. The incidence and characteristics of SEI were investigated in 28 patients who underwent simple coiling during the same period, and the results were compared with the SAC group. Results : In the diffusion-weighted imaging obtained on the 1st day after SAC, a total of 106 SEI lesions were observed in 48 (50%) of 96 patients. Of these 48 patients, 38 (79.2%) had 1-3 lesions. Of 106 lesions, 74 (69.8%) had a diameter less than 3 mm. SEI occurred more frequently in older patients (≥60 years, p=0.013). The volume of SEI was found to be significantly increased in older age (≥60 years, p=0.032), hypertension (p=0.036), and aneurysm size ≥5 mm (p=0.047). The incidence and mean volume of SEI in the SAC group (n=96) were similar to those of the simple coiling group (n=28) during the same period. Conclusion : SEIs are common after NAS-assisted coiling. Their incidence in SAC was comparable to that in simple coiling. They occurred more frequently at an older age. Therefore, the use of NAS in the treatment of unruptured intracranial aneurysm does not seem to be associated with an increased risk of thromboembolic events if antiplatelet premedication has been performed well.

• Nuclear Medicine and Molecular Imaging
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• 제41권1호
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• pp.49-53
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• 2007

목적: CT를 사용한 측정감쇠보정(measured attenuation correction; CT-MAC) PET 영상은 $^{68}Ge$을 사용한 분할감쇠보정(segmented attenuation correction; Ge-SAC) PET 영상보다 섭취값이 높은 것으로 알려져 있다. 이 연구에서는 정상인과 암으로 진단된 또는 암이 의심되는 환자를 대상으로 $^{18}F-FDG$ PET을 시행하고, 감쇠보정방법을 달리하여 각각 4가지 PET 영상을 얻고 이를 서로 정량적으로 비교하였다. 대상 및 방법: 5명의 정상인(남:여=4:1; 평균나이, $29.4{\pm}2.5$세)과 35명의 환자(남17, 여18; 평균나이 $52.7{\pm}15.2$세)를 대상으로 $^{18}F-FDG$ PET을 시행하였다. 먼저, CT 영상(140 KeV, 80 mAs)을 얻은 뒤 방출영상(5 min/bed)과 $^{68}Ge$ 투과영상(3 min/bed)을 차례로 얻었다. Ordered subsets expectation maximization (28 subsets, 2 iterations) 영상재구성법과 CT-MAC, CT-SAC, Ge-MAC, Ge-SAC의 4가지 감쇠보정방법을 사용하여 4가지 PET 영상을 얻었다. 정상인군에서는 대표적인 정상조직의, 환자군에서는 비정상적인 섭취를 보이는 병소의 SUV를 구하고, 이를 서로 비교 하였다. 결과: 정상인 군에서 CT-MAC 사용하여 감쇠보정한 PET 영상의 18개 정상조직의 SUV는 나머지 3가지 종류의 PET 영상에 비하여 모두 유의하게 높았다($3.1%{\sim}4.1%$; p<0.001). 환자군에서는 총 145개 병소의 국소 FDG 섭취증가 병변이 발견되었다. CT-MAC 사용한 PET 영상의 SUV 값은 나머지 3가지 PET 영상에 비하여 모두 유의하게 높았다($2.4%{\sim}5.1%$; p<0.001). Ge-MAC 사용한 PET 영상의 SUV 값은 CT-SAC와 Ge-SAC 사용한 PET 영상에 비하여 유의하게 높았다(p<0.001). 그러나, CT-SAC와 Ge-SAC PET 영상사이의 SUV에는 유의한 차이가 없었다. 폐병변에서는 감쇠보정방법사이에 섭취값이 유의한 차이가 없는 반면, 뼈병변에서는 이러한 차이가 가장 컸다($3.8%{\sim}9.6%$; p<0.01). 결론: $^{18}F-FDG$ PET 영상에서 섭취값은 CT-MAC로 감쇠보정을 했을 때에 가장 높다. CT 감쇠보정 및 MAC 사용, 2가지 모두가 이 차이에 기여했을 것이며, 이 중 MAC 사용이 더 크게 작용한 것으로 보인다. 감쇠보정방법이 다른 PET 영상들사이의 섭취값을 비교할 때는 이러한 차이를 고려해야 할 것이다.