• Title/Summary/Keyword: S670e

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PGE2 Mediated INF-γ Gene Methylation Through cAMP Signaling Pathway in Human Jurkat T Cells (인간의 Jurkat T세포에서 프로스타글란딘 PGE2) (PGE2)의 cAMP 경로를 통한 인터페론 감마(INF--γ ) 유전자의 methylation)

  • Jeon, Byung-Hun;Ju, Sung-Min;Jeong, Jae-Sung;Kim, Myung-Wan;Yun, Young-Gab;Park, Hyun;Chung Hun-taeg;Han, Dong-Min;Kim, Won-Sin
    • Journal of Life Science
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    • v.14 no.4
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    • pp.670-675
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    • 2004
  • We have examined the effects of S-nitroso-N-acetylpenicillamine (SNAP), prostaglandin $E_2$ (PG $E_2$) and dibutric cyclic AMP (dbcAMP) on the methylation of interferon- ${\gamma}$ (IFN- ${\gamma}$ ) gene in human Jurkat T cells. The CpG dinucleotide which is critical for promoter function of IFN- ${\gamma}$ gene was methylated by treatment with SNAP, PG $E_2$ and dbcAMP, respectively. The DNA methylation induced by PG $E_2$ was suppressed by the addition of 2',5'-dideoxyadenosine (DDA), an inhibitor of adenylyl cyclase, but the suppression was not observed in SNAP treated cells. The NO production was not enhanced in PG $E_2$ or dbcAMP treated cells. The methylation induced by PG $E_2$ and dbcAMP was not suppressed by the addition of $N^{G}$-methyl-L-arginine (L-NMMA), NO synthase inhibitor. In conclusion, the inhibition of INF- ${\gamma}$ gene expression by PG $E_2$ was associated with the methylation of INF- ${\gamma}$ gene by elevation of intracellular cAMP in human Jurkat T cells. However, the methylation induced by PG $E_2$ might not be mediated through the NO production.rough the NO production.

A Study on the Development and Performance Test of the Non-gravity Fluidized Dryer (무중력 유동층 건조기 개발과 성능평가)

  • Han, J.W.;Kum, S.M.;Lee, C.E.
    • Proceedings of the KSME Conference
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    • 2001.06d
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    • pp.665-670
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    • 2001
  • The purpose of this study is to develop a new type dryer, which is to proceed mixing and drying of wet-materials at the same time and drying process is carried out in a closed system. In this drying system, thermal contact occurs, when a fluidized zone is created by paddle mechanism. Accordingly, wet-materials is dried in a short time without any damage. Also wet-materials could be dried uniformly to low moisture contents. It is suitable to dry a small quantity of multi-kind materials. And drying process is carried out in a closed system, so as for environmental pollution dust not to be emitted into the atmosphere. Accordingly, it could be used to dry not only food and chemical materials, but also environmental pollution materials.

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Developing an Automatic Classification System for Botanical Literatures (식물학문헌을 위한 자동분류시스템의 개발)

  • 김정현;이경호
    • Journal of Korean Library and Information Science Society
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    • v.32 no.4
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    • pp.99-117
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    • 2001
  • This paper reports on the development of an automatic book classification system using the faced classification principles of CC(Colon Classification). To conduct this study, some 670 words in the botanical field were selected, analyzed in terms [P], [M], [E], [S], [T] employed in CC 7, and included in a database for classification. The principle of an automatic classification system is to create classification numbers automatically through automatic subject recognition and processing of key words in titles through the facet combination method of CC. Particularly, a classification database was designed along with a matrix-principle specifying the subject field for each word, which can allow automatic subject recognition possible.

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The Model Predicting Disqualified Medicine Operation Experience Pattern (치과 무자격 의술자의 시술 경험 패턴 연구 : 2006 국민 구강건강 실태조사 자료)

  • Kim, E.Y.;Ham, S.W.;Lim, K.O.;Pu, Y.K.
    • Proceedings of the KAIS Fall Conference
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    • 2010.05b
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    • pp.670-672
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    • 2010
  • 본 연구에서는 치과치료를 무자격 의술자에게 받은 사람들의 특성을 파악하고자 하였다. 2006년 국민구강건강 실태조사 자료를 이용하였다. 본 연구 대상자는 755명으로 치과 무자격시술 경험 유무에 따라 그룹을 나누었다. 무자격 시술 예측 모형을 기 분석에서 살아남은 변수로 CART 모형으로 예측한 결과는 다음과 같다. 의료보험 종류가 의료급여 1종중 66.67%가 무자격 시술경험을 할 것으로 예측되었으나, 직장 또는 미가입 자는 15.46%만 무자격 시술경험을 할 것으로 예측되었다. 연령은 66.5세를 기준으로 66.5세 이상에 해당하는 사람들은 30.0%가 무자격 시술경험을 할 것으로 예측되었으나, 66.5세 미만은 72.7%가 무자격 시술을 경험하는 것으로 나타났다.

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A Research on the Changes of Wedding Dress′ Colors (웨딩드레스 색상의 변천과정 연구)

  • 이윤정
    • The Research Journal of the Costume Culture
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    • v.11 no.5
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    • pp.657-670
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    • 2003
  • It is quite common today for bride to wear white-colored wedding-dress in wedding ceremony. When does the color date back to? What does the “white” mean? Which other colors had been used for wedding dress and why? This research paper aims to answer those historical questions through literature review. It is found here that the “white” began to be generally accepted for a wedding dress color in the 18th century, and that the color became an official one since the marriage of Queen Victoria's (i.e. 1840). Prior to that, other colors were taken rather than the “white”. In ancient Greece and Roma, “Red” and “Yellow” were used to remove devils or to bring fortune. In medieval society, luxurious wedding dresses were popular and various colors were adopted in order to show up family power among leading classes. The “White” has meant purity of bride since the 18th century. However, two world wars in the 20th century happened to lead some brides in economic difficulty wear “black” colored wedding dress for a practical reason. After the world wars, some light colors such as white, beige, ivory are to be used in wedding dress.

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Gibbs Energy of Nonrandomly Mixed Lattice Solutions with a Specific Interaction (특정 상호작용을 갖는 논랜덤 혼합 격자 용액의 깁스 에너지)

  • Jung, Hae-Young
    • Journal of the Korean Chemical Society
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    • v.53 no.6
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    • pp.663-670
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    • 2009
  • Performing random number simulations, we obtained an approximate distribution of the number of ways arranging molecules in a binary lattice solution of nonrandom mixing with a specific interaction. From the distribution an approximate equation of excess Gibbs energy for a binary lattice solution was derived. Using the equation, liquid-vapor equilibrium at constant pressure for 15 binary solutions were calculated and compared with the result from Wilson equation, Van Laar equation and Redlich-Kister equation.

Wet Cupping (al-hijama) for Mental Health: A Systematic Review

  • Ucun, Yasemin
    • Journal of Acupuncture Research
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    • v.39 no.2
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    • pp.89-95
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    • 2022
  • This systematic review aimed to evaluate the effects of wet cupping on the treatment of mental illness. A total of 2,670 studies were retrieved using PubMed, Cochrane Library, Web of Science, Google Scholar, and Science Direct databases, and of these, 2,661 were excluded due to not meeting the inclusion criteria. There were 9 articles included in this review including 1,124 individuals who received wet cupping. Mental health was explored in, those who had migraines, metabolic syndrome, smoking addiction, post-traumatic stress, chronic medical disease, and depression. As an intervention procedure, the triple S technique was used in all studies. Only 3 studies reported that none of the participants complained of adverse events during or after the cupping therapy. In all studies, wet cupping was reported to be effective in reducing psychological symptoms. However, there are few randomized controlled trials testing the e?ectiveness of wet cupping in the treatment of mental health, and most are of poor quality. Therefore, more rigorous studies are required before the effectiveness of wet cupping for the treatment of mental illness can be determined.

A Study on DataWarehouse for Client's Distinguish Information Protection System (DW(DataWarehouse) 고객식별자정보 유출 방지를 위한 시스템 구현 사례 연구)

  • Yu, Jae-Yong
    • Proceedings of the Korea Information Processing Society Conference
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    • 2009.11a
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    • pp.669-670
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    • 2009
  • 기업 내부적으로 고객의 정보를 다루는 DataWarehouse 시스템에 대한 활용도가 증대되고 있다. 특히 고객 식별자 정보(주민번호, 고객성명, 전화번호, E-mail, 주소)에 대한 접근을 통해 데이터를 추출하여 분석하고 이를 마케팅이나 고객 Segment 를 위해 활용이 증대되고 있다. 따라서 민감한 고객의 고객의 정보를 전사적인 차원에서 체계적인 관리를 위한 시스템이 필요하다. 본 논문에서는 DW 고객 식별자 정보 이용절차를 개선하여 대량정보 유출 및 불법 이용을 사전에 예방하고 사후 보안 체계를 강화하는 시스템을 구현 모델을 설명하며, 그 결과로 사용자, 관리자, 감사자까지의 각 단계별 검증 프로세스를 통한 고객 식별자 정보 관리의 극대화 방향을 제시한다.

Relationship between Abnormal Hyperintensity on T2-Weighted Images Around Developmental Venous Anomalies and Magnetic Susceptibility of Their Collecting Veins: In-Vivo Quantitative Susceptibility Mapping Study

  • Yangsean Choi;Jinhee Jang;Yoonho Nam;Na-Young Shin;Hyun Seok Choi;So-Lyung Jung;Kook-Jin Ahn;Bum-soo Kim
    • Korean Journal of Radiology
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    • v.20 no.4
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    • pp.662-670
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    • 2019
  • Objective: A developmental venous anomaly (DVA) is a vascular malformation of ambiguous clinical significance. We aimed to quantify the susceptibility of draining veins (χvein) in DVA and determine its significance with respect to oxygen metabolism using quantitative susceptibility mapping (QSM). Materials and Methods: Brain magnetic resonance imaging of 27 consecutive patients with incidentally detected DVAs were retrospectively reviewed. Based on the presence of abnormal hyperintensity on T2-weighted images (T2WI) in the brain parenchyma adjacent to DVA, the patients were grouped into edema (E+, n = 9) and non-edema (E-, n = 18) groups. A 3T MR scanner was used to obtain fully flow-compensated gradient echo images for susceptibility-weighted imaging with source images used for QSM processing. The χvein was measured semi-automatically using QSM. The normalized χvein was also estimated. Clinical and MR measurements were compared between the E+ and E- groups using Student's t-test or Mann-Whitney U test. Correlations between the χvein and area of hyperintensity on T2WI and between χvein and diameter of the collecting veins were assessed. The correlation coefficient was also calculated using normalized veins. Results: The DVAs of the E+ group had significantly higher χvein (196.5 ± 27.9 vs. 167.7 ± 33.6, p = 0.036) and larger diameter of the draining veins (p = 0.006), and patients were older (p = 0.006) than those in the E- group. The χvein was also linearly correlated with the hyperintense area on T2WI (r = 0.633, 95% confidence interval 0.333-0.817, p < 0.001). Conclusion: DVAs with abnormal hyperintensity on T2WI have higher susceptibility values for draining veins, indicating an increased oxygen extraction fraction that might be associated with venous congestion.

Growth and Characterization of CuGaTe$_2$ Sing1e Crystal Thin Films by Hot Wall Epitaxy (Hot Wall Epitaxy (HWE) 방법에 의한 CuGaTe$_2$ 단결정 박막 성장과 특성)

  • 유상하;홍광준
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 2002.07a
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    • pp.273-280
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    • 2002
  • The stochiometric mix of evaporating materials for the CuGaTe$_2$ single crystal thin films was prepared from horizontal furnance. For extrapolation method of X-ray diffraction patterns for the CuGaTe$_2$ polycrystal, it was found tetragonal structure whose lattice constant a$\_$0/ and c$\_$0/ were 6.025 ${\AA}$ and 11.931 ${\AA}$, respectively. To obtain the single crystal thin films, CuGaTe$_2$ mixed crystal was deposited on throughly etched semi-insulator GaAs(100) substrate by the Hot Wall Epitaxy (HWE) system. The source and substrate temperature were 670 $^{\circ}C$ and 410 $^{\circ}C$ respective1y, and the thickness of the single crystal thin films is 2.1 $\mu\textrm{m}$. The crystalline structure of single crystalthin films was investigated by the photoluminescence and double crystal X-ray diffraction (DCXD). Hall effect on this sample was measured by the method of van der Pauw and studied on carrier density and mobility dependence on temperature. The carrier density and mobility of CuGaTe$_2$ single crystal thin films deduced from Hall data are 8.72${\times}$10$\^$23/㎥, 3.42${\times}$10$\^$-2/㎡/V$.$s at 293K, respectively. From the photocurrent spectrum by illumination of perpendicular light on the c - axis of the CuGaTe$_2$ single crystal thin film, we have found that the values of spin orbit coupling Δs.o and the crystal field splitting Δcr were 0.0791 eV and 0/2463eV at 10K, respectively. From the PL spectra at 10K, the peaks corresponding to free bound excitons and D-A pair and a broad emission band due to SA is identified. The binding energy of the free excitons are determined to be 0.0470eV and the dissipation energy of the donor -bound exciton and acceptor-bound exciton to be 0.0490eV, 0.00558eV, respectively.

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