• 제목/요약/키워드: S670e

검색결과 36건 처리시간 0.028초

인간의 Jurkat T세포에서 프로스타글란딘 PGE2) (PGE2)의 cAMP 경로를 통한 인터페론 감마(INF--γ ) 유전자의 methylation (PGE2 Mediated INF-γ Gene Methylation Through cAMP Signaling Pathway in Human Jurkat T Cells)

  • 전병훈;주성민;정재성;김명완;윤용갑;박현;정헌택;한동민;김원신
    • 생명과학회지
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    • 제14권4호
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    • pp.670-675
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    • 2004
  • 본 연구에서 인간의 백혈병세포주인 Jurkat T 세포에서 인터페론 감마(INF-${\gamma}$ 유전자의 methylation에 대한 S-nitroso-N-acetylpenicillamine (SNAP), 프로스타글란딘 $E_2$ (PG $E_2$) 그리고 dibutric cyclic AMP (dbcAMP)의 효과를 조사하였다. 인터페론 감마 유전자의 프로모터기능에 아주 중요한 디뉴클레오티드인 CpG는 SNAP, PG $E_2$, 그리고 dbcAMP를 각각 처리하였을 때 methylation되었다. PG $E_2$에 의해서 유도된 그 methylation은 아데닐산 사이클라제의 저해제의 하나인 2',5'-dideoxyadenosine (DDA)에 의해서 억제되었지만, SNAP에 의해서 유도된 methylation은 DDA에 의해서 억제되지 않았다. PG $E_2$나 dbcAMP를 처리한 세포에서 일산화질소(NO)의 생성의 증가는 나타나지 않았으며, PG $E_2$나 dbcAMP에 의해 유도된 인터페론 감마유전자의 methylation도 일산화질소합 성효소의 저해제인 $N^{G}$ -methyl-L-arginine (L-NMMA)에 의해서 억제되지 않았다. 따라서 인간의 Jurkat T 세포에서 PG $E_2$에 의한 인터페론 감마 유전자의 발현 억제는 세포내의 cAMP생성경로를 통한 인터페론 감마 유전자의 methylation과 연관되어있으나 일산화질소의 생성경로와는 무관한 것으로 보인다.화질소의 생성경로와는 무관한 것으로 보인다.

무중력 유동층 건조기 개발과 성능평가 (A Study on the Development and Performance Test of the Non-gravity Fluidized Dryer)

  • 한지웅;금성민;이창언
    • 대한기계학회:학술대회논문집
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    • 대한기계학회 2001년도 춘계학술대회논문집D
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    • pp.665-670
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    • 2001
  • The purpose of this study is to develop a new type dryer, which is to proceed mixing and drying of wet-materials at the same time and drying process is carried out in a closed system. In this drying system, thermal contact occurs, when a fluidized zone is created by paddle mechanism. Accordingly, wet-materials is dried in a short time without any damage. Also wet-materials could be dried uniformly to low moisture contents. It is suitable to dry a small quantity of multi-kind materials. And drying process is carried out in a closed system, so as for environmental pollution dust not to be emitted into the atmosphere. Accordingly, it could be used to dry not only food and chemical materials, but also environmental pollution materials.

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식물학문헌을 위한 자동분류시스템의 개발 (Developing an Automatic Classification System for Botanical Literatures)

  • 김정현;이경호
    • 한국도서관정보학회지
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    • 제32권4호
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    • pp.99-117
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    • 2001
  • 본 연구는 분류자동화를 위해 이미 연구된 바 있는 농학 및 의학분야의 AutoBC 시스템에 대한 계속적인 연구의 일환으로 식물학분야의 문헌에 대해 분류자동화가 가능한지의 여부를 CC의 원리를 응용하여 실험 및 검증한 것이다. 분류자동화를 위한 데이터베이스는 원통형과 행렬식의 원리에 의해 설계되었으며, 문헌의 표제나 키워드를 입력하여 자동적인 주제인지 및 분류기호가 생성될 수 있는 윈도우용 자동분류시스템을 새로이 개발하여 실험하였다.

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치과 무자격 의술자의 시술 경험 패턴 연구 : 2006 국민 구강건강 실태조사 자료 (The Model Predicting Disqualified Medicine Operation Experience Pattern)

  • 김은엽;함승우;임근옥;부유경
    • 한국산학기술학회:학술대회논문집
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    • 한국산학기술학회 2010년도 춘계학술발표논문집 2부
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    • pp.670-672
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    • 2010
  • 본 연구에서는 치과치료를 무자격 의술자에게 받은 사람들의 특성을 파악하고자 하였다. 2006년 국민구강건강 실태조사 자료를 이용하였다. 본 연구 대상자는 755명으로 치과 무자격시술 경험 유무에 따라 그룹을 나누었다. 무자격 시술 예측 모형을 기 분석에서 살아남은 변수로 CART 모형으로 예측한 결과는 다음과 같다. 의료보험 종류가 의료급여 1종중 66.67%가 무자격 시술경험을 할 것으로 예측되었으나, 직장 또는 미가입 자는 15.46%만 무자격 시술경험을 할 것으로 예측되었다. 연령은 66.5세를 기준으로 66.5세 이상에 해당하는 사람들은 30.0%가 무자격 시술경험을 할 것으로 예측되었으나, 66.5세 미만은 72.7%가 무자격 시술을 경험하는 것으로 나타났다.

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웨딩드레스 색상의 변천과정 연구 (A Research on the Changes of Wedding Dress′ Colors)

  • 이윤정
    • 복식문화연구
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    • 제11권5호
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    • pp.657-670
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    • 2003
  • It is quite common today for bride to wear white-colored wedding-dress in wedding ceremony. When does the color date back to? What does the “white” mean? Which other colors had been used for wedding dress and why? This research paper aims to answer those historical questions through literature review. It is found here that the “white” began to be generally accepted for a wedding dress color in the 18th century, and that the color became an official one since the marriage of Queen Victoria's (i.e. 1840). Prior to that, other colors were taken rather than the “white”. In ancient Greece and Roma, “Red” and “Yellow” were used to remove devils or to bring fortune. In medieval society, luxurious wedding dresses were popular and various colors were adopted in order to show up family power among leading classes. The “White” has meant purity of bride since the 18th century. However, two world wars in the 20th century happened to lead some brides in economic difficulty wear “black” colored wedding dress for a practical reason. After the world wars, some light colors such as white, beige, ivory are to be used in wedding dress.

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특정 상호작용을 갖는 논랜덤 혼합 격자 용액의 깁스 에너지 (Gibbs Energy of Nonrandomly Mixed Lattice Solutions with a Specific Interaction)

  • 정해영
    • 대한화학회지
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    • 제53권6호
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    • pp.663-670
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    • 2009
  • 논랜덤 혼합의 2-성분 격자용액에서 특정상호작용을 갖는 경우의 수에 대한 분포를 난수 모의실험을 통하여 구하였다. 이 분포로부터 2-성분격자용액의 과잉깁스에너지 $G^E$에 대한 근사식을 유도하였다. 이 식을 사용하여 15개의 2-성분용액에 대한 일정압력에서의 액체-증기 상평형 계산을 하였고 Wilson식, Van Laar식, Redlich-Kister식의 계산 결과와 비교하여 보았다.

Wet Cupping (al-hijama) for Mental Health: A Systematic Review

  • Ucun, Yasemin
    • Journal of Acupuncture Research
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    • 제39권2호
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    • pp.89-95
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    • 2022
  • This systematic review aimed to evaluate the effects of wet cupping on the treatment of mental illness. A total of 2,670 studies were retrieved using PubMed, Cochrane Library, Web of Science, Google Scholar, and Science Direct databases, and of these, 2,661 were excluded due to not meeting the inclusion criteria. There were 9 articles included in this review including 1,124 individuals who received wet cupping. Mental health was explored in, those who had migraines, metabolic syndrome, smoking addiction, post-traumatic stress, chronic medical disease, and depression. As an intervention procedure, the triple S technique was used in all studies. Only 3 studies reported that none of the participants complained of adverse events during or after the cupping therapy. In all studies, wet cupping was reported to be effective in reducing psychological symptoms. However, there are few randomized controlled trials testing the e?ectiveness of wet cupping in the treatment of mental health, and most are of poor quality. Therefore, more rigorous studies are required before the effectiveness of wet cupping for the treatment of mental illness can be determined.

DW(DataWarehouse) 고객식별자정보 유출 방지를 위한 시스템 구현 사례 연구 (A Study on DataWarehouse for Client's Distinguish Information Protection System)

  • 유재용
    • 한국정보처리학회:학술대회논문집
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    • 한국정보처리학회 2009년도 추계학술발표대회
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    • pp.669-670
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    • 2009
  • 기업 내부적으로 고객의 정보를 다루는 DataWarehouse 시스템에 대한 활용도가 증대되고 있다. 특히 고객 식별자 정보(주민번호, 고객성명, 전화번호, E-mail, 주소)에 대한 접근을 통해 데이터를 추출하여 분석하고 이를 마케팅이나 고객 Segment 를 위해 활용이 증대되고 있다. 따라서 민감한 고객의 고객의 정보를 전사적인 차원에서 체계적인 관리를 위한 시스템이 필요하다. 본 논문에서는 DW 고객 식별자 정보 이용절차를 개선하여 대량정보 유출 및 불법 이용을 사전에 예방하고 사후 보안 체계를 강화하는 시스템을 구현 모델을 설명하며, 그 결과로 사용자, 관리자, 감사자까지의 각 단계별 검증 프로세스를 통한 고객 식별자 정보 관리의 극대화 방향을 제시한다.

Relationship between Abnormal Hyperintensity on T2-Weighted Images Around Developmental Venous Anomalies and Magnetic Susceptibility of Their Collecting Veins: In-Vivo Quantitative Susceptibility Mapping Study

  • Yangsean Choi;Jinhee Jang;Yoonho Nam;Na-Young Shin;Hyun Seok Choi;So-Lyung Jung;Kook-Jin Ahn;Bum-soo Kim
    • Korean Journal of Radiology
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    • 제20권4호
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    • pp.662-670
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    • 2019
  • Objective: A developmental venous anomaly (DVA) is a vascular malformation of ambiguous clinical significance. We aimed to quantify the susceptibility of draining veins (χvein) in DVA and determine its significance with respect to oxygen metabolism using quantitative susceptibility mapping (QSM). Materials and Methods: Brain magnetic resonance imaging of 27 consecutive patients with incidentally detected DVAs were retrospectively reviewed. Based on the presence of abnormal hyperintensity on T2-weighted images (T2WI) in the brain parenchyma adjacent to DVA, the patients were grouped into edema (E+, n = 9) and non-edema (E-, n = 18) groups. A 3T MR scanner was used to obtain fully flow-compensated gradient echo images for susceptibility-weighted imaging with source images used for QSM processing. The χvein was measured semi-automatically using QSM. The normalized χvein was also estimated. Clinical and MR measurements were compared between the E+ and E- groups using Student's t-test or Mann-Whitney U test. Correlations between the χvein and area of hyperintensity on T2WI and between χvein and diameter of the collecting veins were assessed. The correlation coefficient was also calculated using normalized veins. Results: The DVAs of the E+ group had significantly higher χvein (196.5 ± 27.9 vs. 167.7 ± 33.6, p = 0.036) and larger diameter of the draining veins (p = 0.006), and patients were older (p = 0.006) than those in the E- group. The χvein was also linearly correlated with the hyperintense area on T2WI (r = 0.633, 95% confidence interval 0.333-0.817, p < 0.001). Conclusion: DVAs with abnormal hyperintensity on T2WI have higher susceptibility values for draining veins, indicating an increased oxygen extraction fraction that might be associated with venous congestion.

Hot Wall Epitaxy (HWE) 방법에 의한 CuGaTe$_2$ 단결정 박막 성장과 특성 (Growth and Characterization of CuGaTe$_2$ Sing1e Crystal Thin Films by Hot Wall Epitaxy)

  • 유상하;홍광준
    • 한국전기전자재료학회:학술대회논문집
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    • 한국전기전자재료학회 2002년도 하계학술대회 논문집
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    • pp.273-280
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    • 2002
  • The stochiometric mix of evaporating materials for the CuGaTe$_2$ single crystal thin films was prepared from horizontal furnance. For extrapolation method of X-ray diffraction patterns for the CuGaTe$_2$ polycrystal, it was found tetragonal structure whose lattice constant a$\_$0/ and c$\_$0/ were 6.025 ${\AA}$ and 11.931 ${\AA}$, respectively. To obtain the single crystal thin films, CuGaTe$_2$ mixed crystal was deposited on throughly etched semi-insulator GaAs(100) substrate by the Hot Wall Epitaxy (HWE) system. The source and substrate temperature were 670 $^{\circ}C$ and 410 $^{\circ}C$ respective1y, and the thickness of the single crystal thin films is 2.1 $\mu\textrm{m}$. The crystalline structure of single crystalthin films was investigated by the photoluminescence and double crystal X-ray diffraction (DCXD). Hall effect on this sample was measured by the method of van der Pauw and studied on carrier density and mobility dependence on temperature. The carrier density and mobility of CuGaTe$_2$ single crystal thin films deduced from Hall data are 8.72${\times}$10$\^$23/㎥, 3.42${\times}$10$\^$-2/㎡/V$.$s at 293K, respectively. From the photocurrent spectrum by illumination of perpendicular light on the c - axis of the CuGaTe$_2$ single crystal thin film, we have found that the values of spin orbit coupling Δs.o and the crystal field splitting Δcr were 0.0791 eV and 0/2463eV at 10K, respectively. From the PL spectra at 10K, the peaks corresponding to free bound excitons and D-A pair and a broad emission band due to SA is identified. The binding energy of the free excitons are determined to be 0.0470eV and the dissipation energy of the donor -bound exciton and acceptor-bound exciton to be 0.0490eV, 0.00558eV, respectively.

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