• Journal of Chest Surgery
• /
• v.32 no.9
• /
• pp.799-805
• /
• 1999

Background: Leakage, stricture formation, and tumor recurrence at the anastomotic site are serious problems after esophagectomy for cancer of the esophagus or cardia. The prevalence of these postoperative complications may be affected by whether an anastomosis is made in the neck or in the chest, therefore a comparison was made between anastomoses made at these two sites. Material and Method: Between 1987 and 1998, 36 patients with cancer of the esophagus underwent transthoracic esophagectomy with cervical(NA, n=20) or thoracic anastomosis(CA, n=16). The tumors were staged postoperatively(stage IIA, n=13; s tage IIB, n=7; stage III, n=16) and were located in the middle thoracic(n=22) or lower thoracic esophagus and cardia(n=14). Result: The overall operative mortality was 8.3%(5% for NA group, 12.5% for CA group). The anastomotic leak rate for the NA group was 15.0% and 12.5% for the CA group. The anastomotic leak rate differed according to the manual(27.3%) or stapled(8.0%) techniques(p < 0.05). The median proximal resection margins in the NA and CA groups were 9.6 cm and 5.8 cm, and the corresponding rates of anastomotic tumor recurrence were 5.3% and 28.6%(p < 0.05). The prevalence of benign stricture formation (defined as moderate/severe dysphagia) was higher in the NA group(36.8%) than in the CA group(21.4%). When an anastomosis was made by the stapled technique, smaller size of the staple increased the prevalence of stricture formation - 41.7% with 25-mm staple and 9.1% with 28-mm staple(p < 0.05). Conclusion: Wider resection margin could decrease the anastomotic tumor recurrence, and the stapled technique could decrease the anastomotic leak. The prevalence of benign stricture was higher in the cervical anastomosis but the anastomotic leak and smaller size(25-mm) of the staple should be considered as risk factors.

• Vending industry
• /
• v.2 no.5 s.6
• /
• pp.56-62
• /
• 2002

담배자판기의 신규설치를 금지하고 기존 설치된 자판기마저 전면철거하도록 하는 보건복지부의 초강력 규제안이 마침내 철회가 되게 되었다. 보건복지부는 올 들어 확대되는 금연정책에 편승, 기존 흡연 구역 내 담배자판기 신규설치를 금지하고, 기존 설치된 제품들마저 전면철거하는 규제를 담은 국민건강증진법 시행령 개정안을 지난 4월 공고하며 그 입법추진을 진행한 바 있다. 이 공고안은 그간 국무총리실 산하 규제개혁위원회 분과위원회에 상정되어 1,2차 심의를 진행해 오다 지난 9월 27일 본회의를 통해 '보건복지부의 흡연구역 내 담배자판기 신규설치 금지 및 기존 자판기 철거는 명백히 영업활동 자유 및 재산권 침해에 해당된다.'는 이유로 이를 철회토록 하는 결정을 진행했다. 이 결정을 담은 국민건강증진법 개정안은 조만간 법제처 심사 및 차관회의 등을 거쳐 최종 확정 되게 된다. 이같은 규제개혁위원회의 결정은 협회를 중심으로 한 산업의 적극적인 대응이 있었기에 가능했다. 성인인증장치 도입을 통해 청소년 흡연문제를 완전, 해결하겠다는 산업계의 적극적인 자율대책에도 불구하고 아예 담배자판기를 뿌리 채 뽑겠다는 보건복지부의 행정만능주의적인 발상은 도저히 수용하지 못할 부당한 처사라는 데 관련업계가 인식을 같이 했다. 따라서 이를 반대하는 산업계 입장을 분명히 하며 분명히 하며 적극적인 저지 대응을 최근까지 진행해 왔다. 협회에서는 1차적으로 보건복지부 건강증진과에 담배자판기 전면철거에 대한 산업계 반대 입장을 피력하는 소견서 제출하고 적극적인 산업계의 반대의지를 피력하는 작업을 진행했다. 또한 청소년보호위원회를 통해 청소년 흡연감소를 위한 성인인증 담배자판기 설치 활용방안 건의하며 담배자판기의 긍정적인 활용측면을 집중 부각시키기도 했다. 재정경제부를 통해서는 담배사업법 관련 담배자판기 설치기준에 대한 질의를 통해 현행 관련법 내에서의 설치기준을 명확히 하기도 했다. 이같은 대응에 있어서의 핵심 설득 논리는 담배자판기가 이제는 성인인증장치 부착을 통해 청소년 및 사회적 위해 요인을 극소화 할 수 있다는 점에 있었다. 과거와는 달리 담배자판기가 오히려 청소년의 담배 구입루트 차단이라는 긍정적 역할을 할 수 있는 시점에 있어 이를 전면규제하기보다는 합법적인 설치 환경을 확보하여 사회적으로 떳떳하게 존재가치를 평가받을 수 있게 해달라는게 산업계의 초지일관의 주장이었던 것. 협회는 이같은 주장이 결코 산업계의 이기만이 아니라 세계적인 추세라는 점, 또 담배자판기를 전면철거까지 하면서 과당규제를 할 명분이 부족하다는 점을 반대논리로 적극 내세웠다. 규제개혁위원회가 이번 공공 이용시설 중 흡연구역으로 지정된 장소 내에 담배자판기는 설치 금지 및 철거규제에 철회권고를 내리게 된 것은 이러한 산업계의 주장을 적극 수용함에 힘입은 바 크다. 규제개혁위원회는 이번 결정의 주된 이유로 우선 기설치된 자판기에 대한 철거는 재산권 침해로 위헌 소지가 있음을 들고 있다. 또한 흡연자를 위한 흡연구역내에서마저 자판기 설치를 금지하는 등의 규제는 과도하며 흡연자의 권익보호 역시도 필요함을 인정하고 있다. 따라서 전면적인 규제보다는 청소년 이용통제 가능한 흡연구역에 한하여 담배자판기를 설치토록한 현행규정의 실질적 관리를 강화하며, 전체적으로 흡연구역을 축소 제한하는 방향으로 추진함이 바람직하다는 의견을 제시했다. 규제개혁위원회의 이번 결정으로 흡연구역 내 담배자판기의 설치는 현행법의 적용을 받게 되며, 산업계의 자율대책대로 성인인증 장치를 부착한 담배자판기의 설치 확대가 크게 촉발될 수 있을 것으로 기대된다. 담배자판기가 적극적이고 능동적인 사회적 역할을 할 수 있을 때 자연 이를 반대할 수 있는 명분도 약해질 수 밖에 없다. 산업계는 보다 신뢰성 있게 청소년 이용을 차단할 수 있는 담배자판기 관련 기술 수준을 향상시켜야 할 것이며, 협회에서는 담배자판기의 공공성과 역할에 대한 지속적인 계몽 홍보를 통해 소비자 인식을 고양시켜 나갈 수 있게 해야 할 것이다. 비록 전면 규제 완화가 어렵고 힘든 길이기는 하지만 소비자에게 신뢰성을 부여하고 청소년의 담배 구입 루트 차단에 혁혁한 역할을 다할 수 있게 된다면 그 입지기반을 재평가 받을 수 있게 될 것이다. 담배자판기의 내일은 이제 암울함이 아닌 서서히 희망을 비치는 쪽으로 급선회되고 있다.

• Korean Journal of Soil Science and Fertilizer
• /
• v.39 no.1
• /
• pp.1-7
• /
• 2006

To designate rural landscape spatially, land use and topographic features for 383 of "Ri"s or "Dong", which is a basic administrative unit in Korea, were analyzed using GIS application. We have categorized rural landscape into three types such as agricultural, natural and urban landscape by land use. On the basis of spatial landscape pattern, rural area could be classified into 6 groups of Mountainous area (MA), Mountainous village area (MV), Developing mountainous village area (DM), Plain agricultural area (PA), Developing plain village area (DP) and Urbanized area (UA) according to the ratios of land for agricultural and urban use as the criteria. In MA, the ratio of upland area including orchard was slightly larger than that of paddy, while that of paddy was about 1.5 times larger than upland in other groups. Forested area was distributed more than two-thirds among natural landscape area in MA, MV and DM. In plain types (PA and DP), the ratio of irrigated paddy was extremely larger than partially irrigated paddy and the ratio of water body area among the natural landscape area was two times as large as that of forested area. The ratio of land for industrial and livestock facilities among urban landscape area were 20% or more in MV, DM and DP, and it means that these facilities are mainly distributed in the developing ru ral area where residents and industry are closely related each other. According to the relative ratio of sloped land of 6 categorized areas, the MA area have lots of land with E and F slopes and MV and DM have all grades of sloped land evenly distributed in relative to other types of rural landscape. It has been showed that PA, DP and UA occupied more than two-thirds of land with A or B slope. In case of the analysis of topological distribution in 6 types of rural landscape, there were overwhelmingly lager highland areas in MA. Conclusively, we have confirmed that 6 types of rural landscape classified by land use pattern in 3 categorized areas such as agricultural, natural and urban landscape area would be useful for the management of rural area. For development of sustainable agriculture and the preservation of rural amenity, proper management ways should be properly applied according to rural landscape patterns.

• Journal of Wetlands Research
• /
• v.17 no.2
• /
• pp.184-192
• /
• 2015

This study is a basic research for low maintenance constructed wetlands which can prevent water quality deterioration due to wetland soils. The purpose of this study is to analyze water quality control mechanisms of constructed wetland on the artificial ground which installed the modular revetment structure(MRS), a device that separates water and soil. This study was then conducted with two different wetland mesocosms (a treatment plot and a control). These mesocosms were monitored to analyze effects of water quality control of the MRS. A treatment plot was built, and separated into soil and water, by filling the MRS with the decomposed granite soil in the mesocosm made of rubber material. A control plot was built where the decomposed granite soils were exposed to water by leaving the soil on the bottom of the mesocosm made of rubber material. Water quality was then analyzed by using Kolmogorov-Smirnov Z examination which then showed that pH, BOD, SS, Chl-a, T-P, T-N had statistically valid difference between a container with the MRS and one without it. According to the analysis of the water quality, the temperature and the EC level came out similarly and both mesocosm showed same level on pH and DO. A treatment plot had higher levels of BOD, SS Chl-a, and T-P. A control plot's T-N value was little lower than that of the treatment plot. This study suggests method of constructed wetlands using the MRS prevents problems occurring in wetland soils: aridity of wetlands by soil erosion, eutrophication, and algal blooms due to nutrients released from wetland soil. These functions of constructed wetland with the MRS increase aesthetic, ecologic, social, and economic value of the wetland. Outcomes of this research will later enable more proficient way of stabilizing water quality and provide data for planning low maintenance constructed wetlands.

• Journal of Wetlands Research
• /
• v.17 no.2
• /
• pp.124-129
• /
• 2015

In order to get as ecological basic data for river restoration, vegetation investigation was conducted in natural river and analysed it synecological methods, such as ordination cluster. 29 plant communities units were identified and the major dominant plant communites were Quercus mongolica community, Pinus densiflora community, Populus davidiana community, Q. variabilis community and Prunus sargentii community. River vegetations were classified into ravine and gorge forest type and riverine softwood forest type. Ravine and gorge forest was dominanted by hardwood which located in steep slope and in high elevation, and riverine softwood forest by softwood, salix spp. Naturality was an important criterion for the selection of rivers, so many of the selected rivers are located in the upper stream and mid stream rather than the lower stream, where more human intervention is involved. Plant communities were consisted of hardwood forest(44 plots, 92%) and softwood forest(4 plot, 8%), respectively. PCA with total layer data showed 5 groups of communities: Q. mongolica community group, Prunus sargentii community group, Pinus densiflora community group, Prunus sargentii community - Pinus densiflora community group and the rest communities group. PCA with tree layer showed 3 groups: Q. mongolica community group, Prunus sargentii community group, and the rest community group. Cluster analysis also a showed a similar communities group to PCA ordination, but Magnolia sieboldii community and Prunus sargentii community were distinguished from the PCA result. From the result, it can be concluded that the plant communities of riparian be divided into hardwood and softwood forest by statistical techniques. It was appropriate to plant species such as Quercus mongolica, Pinus densiflora, Populus davidiana, Quercus variabilis and Prunus sargentii, at levee zone and high water level. And Sliax spp. were appropriate for planted plants at waterfront and low water level. The herb species to be planted on the floodplain were recommanded in the species composition co-occurred with the woody species.

• Korean Journal of Weed Science
• /
• v.5 no.1
• /
• pp.73-84
• /
• 1985

25 tank-mixed combinations between Haloxyfop-methyl at 0, 0.05, 0.1, 0.15 and 0.2 kg ae/ha and Acifluorfen at 0, 0.082, 0.163, 0.245 and 0.326 kg ai/ha were applicated at post-emergence on the late-season cropped soybean(Glycine max) fields predominated by grasses and assessed on the weeding efficacy. A most abundant weed species on the experimented fields were found at September (25 species). The broadleaved weed species and sedges were successively and proportionately emerged by the control rate of grass species. From the mono-treatment of each herbicide, Haloxyfop-methyl was recognized as a highly selective one between grasses and soybean, and Acifluorfen between broadleaf weeds and soybean, respectively. By combined application with both herbicides a synergistic weeding efficacy was detected on total weed species, however antagonistic or additive on each weed groups. Among other traits of soybean, stem dry weight was influenced by weed competitions during October, number of pods per plant during August and seed yields during whole periods. For most effective and reasonable weeding, no less than 0.4 kg ai/ha of each herbicides should be applicated in combinations.

• Korean Journal of Weed Science
• /
• v.12 no.2
• /
• pp.144-157
• /
• 1992

The study was conducted to compare the interprete methods and examine the feasibility of mixture use of oxyfluorfen and bensulfuron in controlling principal Paddy weeds, annuals and perennials. Application ratio of both chemicals were obtained from the combinations of 5 levels(0, 5, 10, 15, 20 g ai/ha) of each chemicals, respectively. All the treatments were applied at 5 days after transplanting and water was maintained at 3.0cm in depth. Shoot fresh-weight of weeds was assessed at 35 days after treatments. Data obtained was analysed by Colby, Isobole, Calculus, Regression and EQM method, respectively. The results from the analysis of variance on the principal weeds treated with oxyfluorfen and bensulfuron showed significant interactions at 1% level on both Echinochloa crus-galli and Eleocharis Kuroguwai, and total species at 0.5% level on both Potamogeton distinctus and Cyperus serotinus, but non significant on Scirpus juncoides and Sagittaria pygmaea. Thereafter, the results of the models applied to Echinochloa crus-galli, Eleocharis kuroguwai and total species were as follows ; 1. The Colby method gave values nearly identical to regression estimate method (both multiplicative models) as provided by Akobundu et al. The Colby method and Regression method indicated synergistic toward Echinochloa curs-galli, and total species, but antagonistic toward Eleocharis kuroguwai. 2. The Isobole method shows synergism on Echinochloa crus-galli at $ID_{50}$, and total species at $ID_{60}$ on Eleochari kuroguwai. 3. The Calculus method gave positive signs for the first differentiation and negative signs for the second differentiation except for some rates on Echinochloa crus-galli and total species, but reverse on Eleocharis kuroguwai. These result does not agree with the observed values. 4. ${\theta}$ value from the EQM method was greater than one at all combinations. This result was quite different from those of other methods. 5. The various models did not show the same results, but mixture of oxyfluorfen and bensulfuron tend to have synergistic effect. Weeding effect also was high. Treatment in terms of two chemical combination was expected to reduce rates, and to enhence weeding efficacy compared with single treatment.

• Korean Journal of Weed Science
• /
• v.12 no.2
• /
• pp.124-131
• /
• 1992

Not only reducing the carry-over effects of quinclorac [3, 7-dichloro-8-quinoline carboxylic acid] used in paddy field to some following vegetable crops but also rationalizing agro-ecology conservation and farm economy, the reducing feasibility of application rates by various cropping patterns and application timing after rice seeding and transplanting. Four cropping patterns namely dry direct seeding(DDS), flooded direct seed(FDS), transplanting of 8 days old early seedlings(EST) and 25 days old machinery seedling(MST) were experimented with 7 application timings as 0, 5, 10, 15, 20, 25, 30 days after seeding/transplanting and 9 levels of application rates as 0, 75, 150, 225, 300, 375, 450, 525, and 600g ai/ha of the chemical, respectively. Within the maximum permitted limit of rice phytotoxicity, the minimum application rate of quinclorac to complete control of Echinochloa crus-galli as influenced by various cropping patterns with application timing could be evaluated as follows : A. Dry direct seeding : The minimized application rate at application timing upto 10 days after seeding (DAS) was counted 150g ai/ha, and delaying upto 15-30 DAS, the rates were increased upto 225-525g ai/ha. B. Flooded direct seeding and transplanting : The application rates were minimized 75g ai/ha at application timing upto 10 days after seeding/transplanting(DAS/T), 150g ai/haupto 15 DAS/T, and 225g ai/ha at later than 20 DAS/T, respectively.

• The Korean Society of Law and Medicine
• /
• v.16 no.2
• /
• pp.263-291
• /
• 2015

In May, 2015, a 68 years old man, who has been Middle East Saudi Arabia and the United Arab Emirates, had high fever, muscle aches, cough and shortness of breath. he went two local hospital near his house and the S Medical Center emergency center. He was diagnosed MERS(Middle East respiratory syndrome) and the diseases had put South Korea the fear of epidemics for three months. Especially, this disease has firstly reported in Middle East Asia in September 2012 and spreaded to twenty-six countries. In 21, July, 2015, European Center for disease prevention and control reported 533 people were died and in South Korea, 186 people were infected, 36 people were died and 16,693 people were isolated from MERS. South Korea government were faced into epidemic control and blamed from public. Especially, hospital acquired infection, disease control chain, opening of information, ventilation, lack of isolation bed, the problem of function of local health center, the issue of reparation for hospital and insurance cover rate, the classification of disease, the role of Korea Centers for disease control and prevention, the culture of visiting hospital to see sick people, the issue of hospital multiple room and other related social support policy. it is time to study and discuss to solve these problems. South Korea citizens felt fear and fright from MERS. What is wore, they thought the dieses were out of their government control. It was unusual case for word except Middle East Asia. numerous tourists canceled visiting korea. South korea economic were severly damaged especially, tourism industry. South korea government should admit that they had failed initial action against MERS and take full reasonability from any damages. The government have to open information to public in terms of epidemic diseases and try to prevent any other epidemic diseases and try to work with local governments.

• Journal of Physiology & Pathology in Korean Medicine
• /
• v.20 no.1
• /
• pp.163-170
• /
• 2006

Nardostachyos Rhizoma (N. Rhizoma) belonging to the family Valerianaceae has been anti-arrhythmic effect, and sedation to the central nerve and a smooth muscle. We reported that the water extract of N. Rhizoma induced apoptotic cell death and differentiation in human promyelocytic leukemia (HL-60) cells. Cytotoxicity of N. Rhizoma was detected only in HL-60 cells (IC50 is about 200 ${\mu}g/ml$). The cytotoxic activity of N. Rhizoma in HL-60 cells was increased in a dose-dependent manner. We used several measures of apoptosis to determine whether these processes were involved in N. Rhizoma-induced apoptotic cell death. The high-dose (200 ${\mu}g/ml$) treatment of N. Rhizoma to HL-60 cells showed cell shrinkage, cell membrane blobbing, apoptotic bodies, and the fragmentation of DNA, suggesting that these cells underwent apoptosis. Treatment of HL-60 cells with N. Rhizoma time-dependently induced activation of caspase-3, caspase-8, and caspase-9 and proteolytic cleavage of poly(ADP-ribose) polymerase. Also, we investigated the effect of N. Rhizoma on cellular differentiation and proliferation in HL-60 cells. Differentiation and proliferation of HL-60 cells was determined through expression of CD11b and CD14 surface antigens using flow cytometry and nitroblue tetrazolium (NBT) assay, and through analysis of cell cycle using propidium iodide assay, respectively. N. Rhizoma induced the differentiation of HL-60 at the low-dose (100 ${\mu}g/ml$) treatment, as shown by increased expression of differentiation surface antigen CD11b, but not CDl4 and increased reducing activity of NBT. When HL-60 cells were treated with N. Rhizoma at concentration of $50{\mu}g/ml\;and\;100{\mu}g/ml$, NBT-reducing activities induced approximately 1.5-fold and 20.0-fold as compared with the control. In contrast, HL-60 cells treated with the N. Rhizoma-ATRA combination showed markedly elevated levels of 26.3-fold at $50{\mu}g/ml$ N. Rhizoma-0.1 ${\mu}M$ ATRA combination and 27.5-fold at 50 ${\mu}g/ml$ N. Rhizoma-0.2 ${\mu}M$ ATRA combination than when treated with N. Rhizoma alone or ATRA alone. It may be that N. Rhizoma plays important roles in synergy with ATRA during differentiation of HL-60 cells. DNA flow-cytometry indicated that N. Rhizoma markedly induced a G1 phase arrest of HL-60 cells. N. Rhizoma-treated HL-60 cells increased the cell population in G1 phase from 32.71% to 42.26%, whereas cell population in G2/M and S phases decreased from 23.61% to 10.33% and from 37.78% to 33.98%, respectively. We examined the change in the $p21^{WAF1/Cip1}\;and\;p27^{Kip1}$ proteins, which are the CKIs related with the G1 phase arrest. The expression of the CDK inhibitor $p27^{Kip1},\;but\;not\;p21^{WAF1/Cip1}$ were markedly increased by N. Rhizoma. Taken together, these results demonstrated that N. Rhizoma induces apoptotic cell death through activation of caspase-3, and potently inhibits the proliferation of HL-60 cells via the G1 phase cell cycle arrest in association with $p27^{Kip1}$ and granulocytic differentiation induction .