• Title/Summary/Keyword: S100A7

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S-100B in Extracranial Fracture Patients Without Head Trauma (두부 손상이 없는 골절 환자에서 혈중 S100B 단백질의 분석)

  • Park, Tae-Woong;Lee, Dong-Hoon;Lee, Sang-Jin;Kim, Sung-Eun;Kim, Chang-Woong
    • Journal of Trauma and Injury
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    • v.22 no.2
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    • pp.123-127
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    • 2009
  • Purpose: There is an increasing amount of evidence that S100B could function as a marker of brain damage. However, the cerebral specificity of S100B has been questioned, so the extracerebral sources of S100B have been paid attention. We performed this investigation to show serum S100B levels after extracranial fracture in patients without current head injury and without prior neurological disease. Methods: At the emergency department, we obtained the blood samples within 6 hours from trauma patients hospitalized with extracranial fractures. S100B levels were compared between one fracture and more than two fractures, and analyzed according to the presence of soft tissue damage. Results: Patients with one fracture and those with more than two fractures did not differ by age (mean, 54.70 vs. 47.03, p=0.130), and there was no significant difference in the male-to-female ratio(33:32 vs. 21:12, p=0.226). In patients with one fracture, the mean value of S-100B was $0.56{\mu}g/L$ (95% CI: 0.35-0.77) whereas in those with more than two fractures, the corresponding value was $1.09{\mu}g/L$ (95% CI: 0.46-1.7, p=0.048). The S100B level of patients with soft tissue damage($1.32{\pm}0.38$) was higher than that of patients without soft tissue damage($0.81{\pm}0.21$), whether one fracture or more than two fractures(p=0.049). Conclusion: We present here that S100B levels were raised in 77% of patients with extracranial fractures without cerebral injury who were hospitalized from the emergency room and that the presence of soft tissue damage contributed to the increased S100B rather than the size of the fractured bone size or the number of fracturest. Thus, this study suggests that soft tissue injury may be considered as an important extracerebral source of S100B.

Effects of Temperature and Light Intensity on the Early Growth of Tetrasporophytes and Gametophytes of Agarophyton vermiculophyllum (꼬시래기의 사분포자체와 배우체의 초기 생장에 대한 온도와 광도의 영향)

  • Lee, Sang Yong;Choi, Han Gil
    • Ocean and Polar Research
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    • v.42 no.2
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    • pp.133-139
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    • 2020
  • The aim of this study is to examine the physiological characteristics of an agarophyte Agarophyton vermiculophyllum (Ohmi) Gurgel, J.N. Norris et Fredericq in the early life stage of tetrasporophytes (2n) and gametophytes (n) to select appropriate seedlings for mariculture. Growth experiments were carried out at the combinations of four temperatures (20, 25, 30, and 35℃) and three light intensity levels (20, 60, and 100 µmol photons m-2 s-1) in the two ontogenetic stages: discoid holdfasts and erect sporelings. Holdfast areas and sporeling lengths of tetrasporophytes and gametophytes were estimated after 14 days in culture. Relative growth rates (RGRs) for holdfast areas were 7.08-28.38% day-1 for tetrasporophytes and 11.58-23.67% day-1 for gametophytes. At 35℃, holdfasts of tetrasporophytes survived with RGRs of 7.08-23.28% day-1 but those of gametophytes died. Maximal holdfast growth of tetrasporophytes occurred at 30℃ and 100 µmol photons m-2 s-1, which were different from gametophytes (25℃ and 100 µmol photons m-2 s-1). RGRs of tetrasporophytic sporelings were 2.93-11.11% day-1 and were between 0.78-10.82% day-1 for gametophytes. Maximal growth of A. vermiculophyllum sporelings occurred at 25℃ and 60 µmol photons m-2 s-1 for tetrasporophytes, and at 20℃ and 100 µmol photons m-2 s-1 for gametophytes. In conclusion, the present results indicate that carpospores could be used as resources of spore-seedling methods having genetic diversity for mass field cultivation because tetrasporophytes showed higher-temperature tolerance and faster-growing ability than gametophytes of A. vermiculophyllum in the discoid holdfast and sporeling stages.

Effect of Lipopolysaccharides Treatment on Uterine Involution in Dairy Cows with Retained Placenta (후산정체 젖소에 있어서 Lipopolysaccharide의 처리가 자궁 회복에 미치는 영향)

  • Baek, K.S.;Park, S.J.;Park, S.B.;Lee, W.S.;Kim, H.S.;Jeong, G.Y.;Ki, K.S.;Suh, G.H.;Jeon, B.S.;Ahn, B.S.;Kim, T.I.
    • Journal of Embryo Transfer
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    • v.21 no.3
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    • pp.233-239
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    • 2006
  • This study was carried out to investigate the effect of intra-uterine infusion of lipopolysaccharides (LPS) on uterine involution in dairy cows with retained placenta. The LPS isolated from Bacteroides helcogenes and Fusobaoterium varium was infused at the rate of 100 ug (n=11) and 200 ug (n=11) with 30 ml of phosphate buffer saline in each cow at 20 days post-partum. The cows in conrol group (n=11) with retained placenta were infused with 30 ml phosphate buffer saline in each cow at 20 days postpartum. Cross-sectional ultrasonography was performed at days 40 postpartum to examine uterine involution and exudate in the all dairy cows in study. The cows in control group have shown 45.5, 27.3 and 27.3% gravid horn with less than 30 mm (normal), $31{\sim}50mm$ (medium) and more than 51 mm (large) in diameter. Respective average values of gravid horn diameter in cows treated with LPS 200 ug were noticed 72.7, 18.2 and 9.1%. However, the gravid horn diameter in all the cows treated with 100 ug of LPS was less than 30 mm. The 18.2, 63.6 and 54.6% cows in the control, LPS 100 ug and LPS 200 ug, respectively, have shown no exudate in uterine cavity. However, the respective rates of small amount of exudate retention in uterine cavity were 45.5, 0.0, and 9.1%. Approximately 36.4% cows in all 3 treated groups have shown minute quantity of exudate. In conclusion, the LPS intra-uterine infusion promoted postpartum uterine involution in dairy cows with retained placenta.

The recombination velocity at III-V compound heterojunctions with applications to Al/$_x$/Ga/$_1-x$/As-GaAs/$_1-y$/Sb/$_y$/ solar cells

  • 김정순
    • 전기의세계
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    • v.28 no.4
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    • pp.53-63
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    • 1979
  • Interface recombination velocity in $Al_{x}$G $a_{1-x}$ As-GaAs and $Al_{0.85}$, G $a_{0.15}$ As-GaA $s_{1-y}$S $b_{y}$ heterojunction systems is studied as a function of lattice mismatch. The results are applied to the design of highly efficient III-V heterojunction solar cells. A horizontal liquid-phase epitaxial growth system was used to prepare p-p-p and p-p-n $Al_{x}$G $a_{1-x}$ As-GaA $s_{1-y}$S $b_{y}$-A $l_{x}$G $a_{1-x}$ As double heterojunction test samples with specified values of x and y. Samples were grown at each composition, with different GaAs and GaAs Sb layer thicknesses. A method was developed to obtain the lattice mismatch and lattice constants in mixed single crystals grown on (100) and (111)B oriented GaAs substrates. In the AlGaAs system, elastic lattice deformation with effective Poisson ratios .mu.$_{eff}$ (100=0.312 and .mu.$_{eff}$ (111B) =0.190 was observed. The lattice constant $a_{0}$ (A $l_{x}$G $a_{1-x}$ As)=5.6532+0.0084x.angs. was obtained at 300K which is in good Agreement with Vegard's law. In the GaAsSb system, although elastic lattice deformation was observed in (111) B-oriented crystals, misfit dislocations reduced the Poisson ratio to zero in (100)-oriented samples. When $a_{0}$ (GaSb)=6.0959 .angs. was assumed at 300K, both (100) and (111)B oriented GaAsSb layers deviated only slightly from Vegard's law. Both (100) and (111)B zero-mismatch $Al_{0.85}$ G $a_{0.15}$As-GaA $s_{1-y}$S $b_{y}$ layers were grown from melts with a weight ratio of $W_{sb}$ / $W_{Ga}$ =0.13 and a growth temperature of 840 to 820 .deg.C. The corresponding Sb compositions were y=0.015 and 0.024 on (100) and (111)B orientations, respectively. This occurs because of a fortuitous in the Sb distribution coefficient with orientation. Interface recombination velocity was estimated from the dependence of the effective minority carrier lifetime on double-heterojunction spacing, using either optical phase-shift or electroluminescence timedecay techniques. The recombination velocity at a (100) interface was reduced from (2 to 3)*10$^{4}$ for y=0 to (6 to 7)*10$^{3}$ cm/sec for lattice-matched $Al_{0.85}$G $a_{0.15}$As-GaA $s_{0.985}$S $b_{0.015}$ Although this reduction is slightly less than that expected from the exponential relationship between interface recombination velocity and lattice mismatch as found in the AlGaAs-GaAs system, solar cells constructed from such a combination of materials should have an excellent spectral response to photons with energies over the full range from 1.4 to 2.6 eV. Similar measurements on a (111) B oriented lattice-matched heterojunction produced some-what larger interface recombination velocities.ities.ities.s.

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Determination of Bioconcentration Factor on Phosphamidon and Profenofos by Flow-through Fish Test (Flow-through fish test를 이용한 Phosphamidon과 Profenofos의 생물농축계수의 측정)

  • Min, Kyung-Jin;Cha, Chun-Geun;Seo, Seol
    • Journal of Food Hygiene and Safety
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    • v.15 no.2
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    • pp.137-143
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    • 2000
  • The present study was performed to investigate the bioconcentration of phosphamidon and profenofos. The BCFs(bioconcentration factors), depuration rate constants and LC$_{50}$ for two pesticides in zebrafish(Brachydanio rerio) were measured by the flow-through system(OECD guideline 305). The results obtained are summarized as follows: The 24-hrs LC$_{50}$, 48-hrs LC$_{50}$, 72-hrs LC.n and 96-hrs LC$_{50}$ were more than 100 mg/l for phosphamidon. The concentration of phosphamidon in zebrafish reached an equilibrium in 12 hrs at low and high concentrations(0.2 mg/l and 1 mg/1). The average BCF values of phosphamidon were less than 1 at low(0.96, n=7) and high concentrations (0.89, n=7) after 12~168 hrs. Depuration rate constants of phosphamidon were 0.18 hr-1 and 0.21 hr-1, half-life of phosphamidon were 3.85 and 3.30 at low and high concentrations(0.2 mg/l and 1 mg/l), respectively, The concentrations of phosphamidon in zebrafish at low and high concentrations were rapidly decreased after 8(0.04 $\mu\textrm{g}$/g) and 12 hrs(0.07 $\mu\textrm{g}$/g). The 24-hrs LC$_{50}$, 48-hrs LC$_{50}$, 72-hrs LC$_{50}$ and 96-hrs LC$_{50}$ were 2.9, 2.6, 2.2 and 2.0 mg/1 for profenofos. The concentration of profenofos in zebrafish reached an equilibrium in 12 hrs at five-hundredth and one-hundredth concentration of 96-hrs LC$_{50}$(0.004 mgA and 0.02 mg/1). The average BCF values of profenofos were 141.9(n=7) and 111.3(n=7) at five-hundredth and one-hundredth concentration of 96-hrs LC$_{50}$(0.004 mg/l and 0.02 mg/1) after 12~168 hrs. Depuration rate constants of profenofos were 0.09 hr$^{-1}$ and 0.10 hr$^{-1}$, half-life of profenofos were 7.70 and 6.93 at five-hundredth and one-hundredth concentration of 96-hrs LC50(0.004 mg/l and 0.02 mg/1), respectively. The concentrations of profenofos in zebrafish at five-hundredth and one-hundredth concentration of 96-hrs LC$_{50}$ decreased agter 8(0.18 $\mu\textrm{g}$/g) and 12 hrs (0.19 $\mu\textrm{g}$/g). The LC$_{50}$ value in zebrafish showed that acute toxicity of profenofos was higher than that of phosphamidon. The BCF values of profenofos were 100 times higher than those of phosphamidon, and depuration rate of phosphamidon was two times faster than that of profenofos.

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Evaporation Heat Transfer and Pressure Drop of R-410A in a 7.0 mm O.D. Microfin Tube at Low Flow Rates (낮은 유량에서 외경 7.0 mm 마이크로핀 튜브 내 R-410A 증발 열전달 및 압력 손실)

  • Kim, Nae-Hyun
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.39 no.9
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    • pp.761-772
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    • 2015
  • Microfin tubes having an outside diameter (O.D.) of 7.0 mm are widely used in residential air conditioning systems and heat pumps. It is known that the mass fluxes for air conditioners and heat pumps under partial load conditions are several tens of $kg/m^2s$. However, literature surveys reveal that previous investigations were limited to mass flux over $100kg/m^2s$. In this study, we conduct R-410A evaporation heat-transfer tests at low mass fluxes ($50-250kg/m^2s$) using a 7.0 mm O.D. microfin tube. During the test, the saturation temperature was maintained at $8^{\circ}C$, and the heat flux was maintained at $4.0kW/m^2$. For comparison purposes, we also test a smooth tube with a 7.0 mm O.D. The results showed that the heat-transfer enhancement factor of the microfin tube increased as the mass flux decreased up to $150kg/m^2s$, which decreased as the mass flux further decreased. The reason for this was attributed to the change of the flow pattern from an annular flow to a stratified flow. Within the test range, the frictional pressure drops of the microfin tube were approximately the same as those of the smooth tube. We then compare experimental data obtained with the predictions obtained for the existing correlations.

Establishment of Optimum Extraction Conditions and Wrinkle Improvement Evaluation of Glycosaminoglycans in Styela plicata (오만둥이(Styela plicata)에서 글리코스아미노글리칸의 최적 추출조건 설정 및 주름개선 효능)

  • Neri, Therese Ariane N.;Choi, Byeong-Dae
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.53 no.5
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    • pp.717-724
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    • 2020
  • Styela plicata are naturally-occurring marine resources easily found along the coastlines that have established their niche as functional food and nutraceuticals ingredient along with their increasing consumer demand. Ascidian contain a large amount of dietary fiber but only the meat has been utilized and consumed while the rest of its parts are discarded. Also, various studies have been conducted on the meat of ascidians while studies on the functionality of the ascidian tunics, which were mostly undervalued, were scarce. In this study, we investigated and explored the glycosaminoglycans (GAGs) contents in the tunics of S. plicata, and their potential use as functional ingredient in pharmaceutical and nutraceutical applications. Sulfated GAGs and uronic acids contents were 8.9-10.7 g/100 g and 9.4-11.3 g/100 g, respectively. Highest GAGs content was extracted with optimum Brix at 7-9. Extraction efficiency using hot water at 121℃ was 4.22% while enzyme extraction using Protamex was more efficient at 5.91%. GAGs extracted from S. plicata tunics exhibited collagenase inhibitory activity of 75.2% at 100 ㎍/mL and procollagen synthesis activity of 80.1% at 100 ㎍/mL.

Assessment of Heavy Metals Contamination in Children's Playground Soil in Seoul (서울시 어린이놀이터 토양의 중금속 오염 평가)

  • So Young Park;Won Hyun Ji
    • Journal of Environmental Impact Assessment
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    • v.32 no.5
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    • pp.269-278
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    • 2023
  • The pollution status of heavy metals in the soils of children's playground was investigated for a sustainable soil environment in urban parks of Seoul. As sampling sites, 281 locations were selected from a 7 districts in the Seoul city. The overall mean concentrations of the heavy metals (Cd 0.21 mg/kg, Cu 5.97 mg/kg, As 2.40 mg/kg, Pb 7.55 mg/kg, Zn 34.08 mg/kg, Ni 4.22 mg/kg, Hg 0.02 mg/kg and Cr6+ not detected.) in the soils of the palygrounds were lower than the worrisome level in criteria for area 1 in Korea soil environment conservation act. In addition, when the soil pollution grade (SPC) was evaluated as an average value, it was found to be less than 100, the first grade, at all points in the seven autonomous districts, indicating thatthe soil was in good soil condition. However, when evaluated as the maximum value, some of the five districts showed values of 100 or more. Therefore, it was found that continuous management and interest of the local government, which is the management body of children's playgrounds, is necessary for a safe soil environment.

Biological Activities of the Vaporized Liquid of Water-boiled Pine Needle (솔잎 열수 증류액의 생리활성 효과)

  • Lee Hyo-Jin;Cui Cheng-Bi;Choi Hyung-Taek;Kim Soo-Hyun;Ham Young-An;Lee Deuk-Sik;Ham Seung-Shi
    • Food Science and Preservation
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    • v.12 no.2
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    • pp.179-183
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    • 2005
  • This study was performed to determine the antioxidative, antimutagenic, and anticancer effects of vaporized liquid of water-boiled pine needle(VLP) using DPPH free radical donating method, Ames test, and cytotoxicity. VLP showed the highest electron donating activities $(18.4\;{\mu}L)$. The inhibition rate of VLP $(200\;{\mu}L/plate)$ in the Salmonella. typhimurium TA100 strain showed $45.9\%$ inhibition against the mutagenesis induced by MNNG. In addition, the suppression of with same concentration of VLP in the S. typhimurium TA100 strains showed $85.5\%$ inhibition against 4NQO, respectively. The suppressions under the same condition against Trp-P-1 in the TA98 and TA100 strains were $91.0\%$ and $62.1\%$, respectively. The cytotoxic effects of VLP against the cell lines with human lung carcinoma (A549), human hepatocellular carcinoma (HepG2) , human gastric carcinoma (AGS), human breast adenocarcinoma (MCF-7) and human cervical adenocarcinoma (HeLa) were inhibited with increase of the VLP concentration. The treatment of $50\;{\mu}L/well$ VLP showed strong cytotoxicities of $78.7\%,\;90.3\%,\;90.8\%,\;62.3\%$ and $93.7\%$ against A549, HepG2, AGS, MCF-7 and HeLa, respectively.

Effect of Electric Conductivity and Potassium Level of the Culture Solution on the air Pollution Sensibility of Perillar Frutescens Suwon 16 (양액의 전기전도도 및 칼륨 수준이 들깨 수원 16호의 대기오염 지표성에 미치는 영향)

  • Kim, Jeong-Gyu;Lee, Yong-Bum;Koh, Kang-Suk
    • Korean Journal of Soil Science and Fertilizer
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    • v.29 no.4
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    • pp.411-418
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    • 1996
  • This experiment was conducted to investigate the effect of electric conductivity (EC) and potassium (K) concentration level in the culture solution on the growth and the air pollution monitoring capability of Perilla frutescens Suwon 16 which was recognized as a possible bioindicator for air pollution. The plants were exposed to $NO_2$, $O_3$, $SO_2$ and $NO_2+SO_2$ within a phytotron at $25^{\circ}C$ (day) or at $20^{\circ}C$(night) with 70% of relative humidity and evaluated the effect of EC and K level on the injury of the plants, The highest dry weights were gained as 16.3 g/plant at 0.5 dS/m of EC and as 32.3 g/plant at 100 and 200mg/l of K concentration, respectively. The diffusive resistances appeared as low values at 0.5 dS/m of EC and at 50, 100mg/l of K concentration. The increasing of the visible injury with increasing the dose of air pollutants could be taken at 0.5. 1.0 ds/m of EC and at 50, 100mg/l of K. The recommendable level of EC and K of the culture solution were 0.5-1.0 dS/m of electric conductivity. 50-100mg/l of K for the plant as an air pollutant biomonitor, when the 7th or 8th leaf was developed.

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