• 제목/요약/키워드: S100A12

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톡소포자충 RH tachyzoites에 대한 감마선 조사가 충체의 숙주세포내 증식에 미치는 영향 (Effects of gamma-irradiation on intracellular proliferation of Toxoplasma gondii RH tachyzoites)

  • 국진아;오성희
    • Parasites, Hosts and Diseases
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    • 제33권3호
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    • pp.173-178
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    • 1995
  • 톡소포자충(RH strain) tachyzoltes를 감마선에 조사하여 인체 백혈병 세포인 HL-60 세포와 정상 마우스의 복강 대식세포에 감염시킨 다음 충체 증식 능력에 어떠한 변화가 오는지 $^3H-uracil$ 흡수시험을 통하여 알아보았다 감마선 조사량은 30, 70, 100및 300 Gy로 하였고 tachyzoite감염은 시켰으나 감마선을 조사하지 않은 비조사군(NI군)과 tachyzoites를 넣지 않고 숙주세포만을 배양한 비감염군을 각각 두었다. 3H-uracil 흡수시험 결과 12-24시간 후 대식세포의 NI 군은 2,190-4,787(countperminute. 이하 같음), HL-60세포의 NI 군은 2,967-8,254의 높은 흡수량을 보였으나. 감마선 조사군은 대식세포 감염시 381-703(100 Gy조사군) 및 218-408(300 Gy조사군), HL-60 세포 감염시 1,911-2,618(30 Gy), 1,253-1,384(70 Gy), 1,013-1,090(100 Gy) 및 483-588(300 Gy)의 흡수량을 각각 보였다. 충체 증식에 대한 억제율은 300 Gy 조사시 12-24시간에 대식세포의 경우 90-92%. HL-60 세포의 경우 80-94%이었다. 이상과 같이 톡소포자충 RH tachyzoites가 감마선 조사 후 세포내 분열증식 능력에 치명적인 영향을 받는다는 것을 uracil 흡수 시험법으로 확인하였다.

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대체 감미료와 high methoxyl pectin을 이용한 저열량 pectin gel의 제조 (Replacement of sucrose with other sweeteners and high methoxyl pectin in low caloric pectin gels)

  • 오혜숙;이명희;문수재
    • 한국식품조리과학회지
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    • 제9권4호
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    • pp.284-288
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    • 1993
  • Replacement of sucrose with sugar alcohols in high methoxyl pectin(HMP) jellies were studied. HMP jellies were sweetened with 100% sucrose, 75% sucrose and 25% maltitol, 50% sucrose and 50% maltitol, and 50% sucrose, 25% maltitol, 12.5% sorbitol and 12.5% mannitol. The effect of sugar alcohols in HMP jellies were investigted. There was only slight differences in sweetness intersity in HMP jellies. Color(p<0.05), texture(p<0.01) and preference(p<0.01) of 100fl sucrose jelly were significantly higher than other Jellies sweetened with sugar and sugar alcohols mixtures. Hunter's L(lightness), a(redness), b(yellowness) values of 100%, sucrose jellies and jellies substituted with maltitol up to 25% were not signignificantly different. But as the ratio and the number of sugar alcohols used for substition were increased, L, a and b values had been lowered signigicantly(p<0.01). Instru-mental characteristics of jelly texture were examined. Hardness of 100% sucrose jelly sweetened with sucrose and 3 kind of sugar alcohols were higher than others(p<0.05). As substitution ratio was higher, springiness and chewiness of HMP jellies were lowered(p<0.01). Springiness of HMP jellies indicated positive correlation with general acceptance of sensory scores at 5% significant level. Brittleness, gum-miness and cohesiveness in all types of jellies were not significantly different.

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수종 치주큐렛의 작업측 마모도의 비교연구 (Evaluation of Wear of Periodontal Curet's Lateral Surface in Working-end)

  • 신동환;임성빈;정진형
    • Journal of Periodontal and Implant Science
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    • 제29권3호
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    • pp.703-715
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    • 1999
  • The purpose of this study was to evaluate the degree of wear of periodontal curet's cutting edges made by three different manufacturers. In the first case of the experiment, this study was done with each new curett in the following three experiment. Twelve new double-ended No. 11/12 Gracy curettes from three different manufacturers (A, B and C) was randomly selected from our stock at first test. They were weared by wear tester with fixed pressure and limited distance. This study measured the width of worn curettes'cutting edge. The results were as follows ; 1)In 50 times experiment, this study discoverd that each manufacturer's curette was appeared with different degree of wear (p<0.01) 2)In 100 times experiment, this study result similarly to the 50 times experiment(p<0.01). 3)In 150 times experiment, the result of this study were alike as the X50 experiment and X100 experiment. In the second case of the experiment, the study was done with a curett of a manufacturer in the following three experiment. Two double-ended No. 11/12 Gracy curette from three different manufactures (A, B and C) was randomly selected from our stock at second test. 1)In 50 times experiment, this study discovered that each manufacturer's curette was appeared with different degree of wear (p<0.05). 2)In 100 times experiment, the result was same, compared with the 50 times experiment. 3)In 150 times experiment, this study also discovered that the result was same with the result of the upper two cases. In conclusion, this study discovered that the two cases of experimental were shown with a same result.

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Transmission Performance Comparison of Direction Detection-Based 100-Gb/s Modulation Formats for Metro Area Optical Networks

  • Chung, Hwan Seok;Chang, Sun Hyok;Lee, Jonghyun;Kim, Kwangjoon
    • ETRI Journal
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    • 제34권6호
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    • pp.800-806
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    • 2012
  • Transmission performances of direct detection-based 100-Gb/s modulation formats are investigated and compared for metro area optical networks. The effects of optical signal-to-noise ratio sensitivity, chromatic dispersion, cross-channel nonlinearity, and transmission distance on the performance of differential 8-ary phase-shift keying (D8PSK), differential phase-shift keying plus three-level amplitude-shift keying (DPSK+3ASK), and dual-carrier differential quaternary phase-shift keying (DC-DQPSK) are evaluated. The performance of coherent dual-polarization quadrature phase-shift keying (DP-QPSK) with block phase estimation and coherent DP-QPSK with digital differential detection are also presented for reference. According to our analysis, all three direct detection modulation formats could transmit a 100-Gb/s signal over several hundred kilometers of a single-mode fiber link. The results also show that DC-DQPSK outperforms D8PSK and DPSK+3ASK, and the performance of DC-DQPSK is comparable to that of coherent DP-QPSK with digital differential detection. The maximum transmission distance of DC-DQPSK is over 1,000 km, which is enough distance for metro applications.

능동산의 양사면에서 식물 군락과 종 분포 (Plant Community and Species Distribution In Both Slopes of the Mt. Neungdong)

  • 허만규
    • 생명과학회지
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    • 제19권6호
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    • pp.693-697
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    • 2009
  • 본 조사는 능동산의 산림지 2곳에 대한 목본류의 다양성 양상을 조사하기 위해 12 plot $(100{\times}100 m)$를 설정하였다. 흉고직경 10 cm 이상의 목본류 2,157 그루를 동정한 결과 총 35과 135종이었다. 최소 유의성 차이(LSD)에서 지역 A (울주군 석남사 방향)가 지역 B (밀양시 얼음골 방향)보다 높았다. Shannon-Wiener의 다양성 지수에서 지역 A는 1.822, 지역 B는 2.118로 두 지역간 유의한 차이가 있었다(F=4.12, p<0.05). 곰솔-갈참나무군락이 두 지역에서 우점 하였다. 그러나 지역 A의 중간 고도는 소나무가 우점인 반면 지역 B의 중간 고도부위는 참나무속 식물군락과 서어나무군락이 우점 하였다. 공간 분포 분석에서 능동산의 동서지역의 식물상은 서로 이질적이며 미세기후와 패치(patchy)구조를 나타내었다.

겸재 정선의 진경산수화에 나타난 조망행동 - 진경산수화 100엽을 대상으로 - (Prospect Behavior in the Analysis of Kyumjae Chung Sun's One Hundred Scenes from the Real Landscape Painting)

  • 강영조;배미경
    • 한국조경학회지
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    • 제30권5호
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    • pp.1-15
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    • 2002
  • The purpose of this study is to consider the relationship between point of view and prospect behavior occurring in the experience of a painted landscape. This study analyzes one hundred scenes from the 'real landscape painting' by Kyumjae, one of the most famous landscape painters in 18th century Korea. The results of the study are as follows: 1. It clarified that Kyumjae's real landscape painting's 100 scenes have many view points such as roads, bridges, pavilions, mansions, towers, terraces, hillsides, bases of mountains, broad flat roots, brooksides, and ferries that are apt to occur in the experience of a landscape. The spatial characteristics of view points are expanded fields of vision, evening and night scenes, edges of landforms and structures from which to improve ones vantage point. 2. It showed that 99 out of real landscape painting's 100 scenes depict a view point'to look'and 79 of 'to look through', 73 of 'look around'and 24 of 'to look over'. 3. It showed that real landscape painting's 100 scenes depict that the view point 'to look' is mainly upon a road from which people are looking over an elevated landscape such as the top of a mountain or rockwall. The view behaviors of looking down are depict 15 pavilions, 14 mansions, 2 broad rocks and 10 mountain tops on which people experience landscapes such as fields, rural communities and streams. The view behaviors to look depict 33 ships, 24 roads, 24 pavilions, 19 mansions and 12 terraces on which people experience landscapes such as distant views of mountains, rivers and landscapes. The view behaviors to look around to obtain orientation of landscape are depict 16 pavilions, 10 mountaintops. To glimpse on the way of journey depict 33 ships and 29 roads. To look over depict 11 mansions and 6 pavilions on which experience borrows the landscape. To look through landscapes such as rivers, mountains and rockwalls depict 15 roads, 14 pavilions and 11 mansions. To exchange looks depict 30 ships, 14 roads, 12 pavilions and 12 mansions. We expect that these results might give clues toward the experience of landscapes and the practice of landscape design methods which select viewpoints, and in the design of view points suitable to prospect behaviors.

비지박 함유 먹이원 급이 흰점박이꽃무지 유충의 영양성분 비교분석 (Comparative Analysis of Nutritional Components of Protaetia brevitarsis Larvae Fed Soybean Curd Cake)

  • 김선영;유태호;지상민;송정훈;김소윤;장규동
    • 생명과학회지
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    • 제32권12호
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    • pp.997-1004
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    • 2022
  • 비지박을 포함하는 먹이원을 급이한 흰점박이꽃무지 유충의 영양학적 우수성과 안전성을 검증하고자 비지박 함유 먹이원과 참나무 발효톱밥만으로 사육한 유충의 영양성분과 유해물질을 비교분석하였다. 조단백질 함량은 비지박 함유 먹이원을 급이한 유충(SCC)에서 50.0%로 참나무 발효톱밥으로 사육한 유충(FOS) 44.7%보다 1.1배 많았다. 다량무기질 중 가장 많은 함량을 나타낸 칼륨은 SCC (3169.6 mg/100 g)에서 FOS(1245.9 mg/100 g)보다 2.5배 더 많았다. 미량무기질 중 아연은 SCC (103.0 mg/100 g)에서 FOS (8.2 mg/100 g)보다 12.6배 높은 함량을 나타냈다. 유해물질 분석 결과, SCC와 FOS에서 납, 카드뮴, 비소 모두 식용곤충 중금속 기준에 적합하였고, 병원성 미생물인 대장균과 살모넬라균은 모두 불검출되었다. 위의 연구 결과에 따르면, 비지박을 급이한 흰점박이꽃무지 유충은 다양한 영양성분을 포함하고 있으며, 안전성 또한 검증되었으므로 식용으로 활용하기에 적합할 것으로 판단된다.

소형화된 헤어핀 링 공진기를 이용한 발진기 설계 및 제작에 관한 연구 (A Study on the Design and Implementation of the Oscillator Using a Miniaturized Hairpin Ring Resonator)

  • 김장구;최병하
    • 한국항행학회논문지
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    • 제12권2호
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    • pp.122-131
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    • 2008
  • 본 논문에서는 마이크로스트립 헤어핀 형태의 링 공진기를 이용하여 저위상 잡음을 개선한 소형화된 S 대역에 사용가능한 발진기를 설계 및 제작하였다. 기판은 고조파 특성이 우수한 유전율 ${\varepsilon}_r$=3.5 기판두께 h=20mil 금속두께 t=17um 손실 탄젠트 $tan{\delta}$=0.0025 인 TACONIC사의 RF-35를 사용하였다. 측정된 결과 발진 주파수는 2.45 GHz에서 출력전력은 20.9 dBm으로서 기존의 발진기에 비하여 상당히 높은 출력을 얻었고, 위상 잡음 특성은 100 kHz offset에서 -100.5 dBc/Hz 로서 기존의 발진기 성능과 비교하면 우수한 특성이 있음을 확인할 수 있었고, 고조파 억압 특성은 32 dBc 이상으로서 우수한 특성을 갖는 발진기임을 보여주었다. 본 논문에서 제안된 발진기의 형태를 이용하여 RFIC, MIC, MMIC 형태로 제작한다면 발진기를 소형화할 수 있을 것이며, 이 제작된 발진기는 S-밴드의 주파수원으로 이용 가능할 수 있을 것으로 사료된다.

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각종 효소를 이용한 맥주 폐효모로부터 효모추출물 제조 (Preparation of Yeast Extract from Waste Brewer's Yeast using Various Enzymes)

  • 이옥환;이성갑;손종연;김경임;김현덕;이부용
    • 한국식품과학회지
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    • 제34권5호
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    • pp.867-872
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    • 2002
  • 정미성이 높은 효모 추출물을 얻고자 각종 효소의 사용에 대한 최적 조합 및 공정법을 알아보기 위하여 맥주 폐효모박을 각종 효소로 처리하여 효모추출물 중의 정미성분(IMP, GMP 및 유리아미노산)을 측정하여 비교, 분석하였다. Glucanase(0.5%) 처리에 의한 효모추출물중의 조단백질 함량은 33.6% 이었다. Tunicase(1%) 28.0% 와 무처리구 21.1%에 비해 최고 1.6배의 증가를 보였다. 단백질 분해효소처리에 의한 조단백질의 함량은 bromelin(1%), protamex(1%) 처리에서 각각 30.8%, 29.8%로 무처리구에 비해 최고 1.4배의 증가를 보였다. 효소 복합처리에 의한 상승효과는 glucanase(0.5%)+protamex(1%) 처리구에서 조단백질의 함량이 34.4%로 나타나 glucanase 단독처리구의 33.6%보다 높은 함량을 나타냈다. IMP+GMP 총함량은 glucanase + phophodiesterase + adenyldeaminase (G+P+A) 혼합 처리구에서 1,066 mg/100 g, glucanase + ptotamex + phophodiesterase + adenyldeaminase (G+Pro+P+A) 혼합 처리구에서는 1,047 mg/100 g으로 비슷하였다. 유리아미노산의 함량은 protamex가 첨가된 G+Pro+P+A 혼합처리구에서 2,302 mg/100 g으로 가장 높게 나타났다. 따라서 IMP, GMP 및 유리아미노산의 함량을 모두 고려해 볼 때 세포벽 분해효소 (gulcanase 0.5%, 12시간), 단백질 분해효소 (protamex 1%, 3시간), 핵산 분해효소 (phosphodiesterase 0.1%, 3시간) 및 핵산 전이효소 (adenyldeaminase 1%, 1.5시간)를 순차적으로 적용시켜 가수분해시키는 것이 효모 추출물의 정미성을 높이는 최적의 효소 복합 사용공정으로 판단되었다.

항암제 취급간호사의 항암제 체내흡수에 관한 조사 (Biological Monitoring on the Absorption of Antineoplastic Drugs in Nursing Personnel)

  • 김봉임
    • 대한간호학회지
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    • 제27권3호
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    • pp.520-530
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    • 1997
  • Antineoplastic agents may exhibit effects not only in patients therapeutically exposed, but also in health workers who prepare and administer these drugs. This study was done to clarify whether nurses who handle anticancer drugs show signs of drug absorption. The experimental group was 14 nurses handling anticancer drugs at three medical wards of a hospital in J city ; the control group was 12 psychiatric nurses at the same hospital. The test materials were the nurses' 24hr urine specimens, which were concentrated by XAD-2 column chromatograpy. Tester strains were TA98(±S9mix), TA100(±S9 mix), TA1535(±S9 mix) and TA1537(±S9 mix) : the salmonella mammalian microsomal test (Ames test) was used for the urinary mutagenicity assay. The results are summarized as follow : 1. In qualitative analysis of the results, both experimental group and control group showed 15.4% urine toxicity. 2. The experimental group revealed significantly higher urinary mutagenicity both in the activation method test and non-activation method test of the tester strains TA98, TA100 and TA1535. In the case of TA1537, the two groups showed no difference in the non-activation method test, but the activation method revealed a difference. 3. In urinary mutagenicity of the experimental group by ward career, there was a significant difference between the group with more than 20 months experience and the group with less than 20 months on the tester strains TA98, TA100, and TA1537. No Significant difference was found between two groups by the tester strain TA1535.

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