• 한국정보디스플레이학회:학술대회논문집
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• 2004.08a
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• pp.471-474
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• 2004

We investigated field emission (FE) characteristics of multi-walled carbon nanotubes (CNTs) grown on all over patterned cathode electrode lines (CL pattern) and grown on along the central areas of the cathode lines(CL pattern). The CNTs grown on the SL pattern showed a lower threshold voltage and higher emission current than those on the CL pattern, due to the concentration of electric fields at the edges of the cathode lines. For the SL-patterned CNTs, however, the FE gradually spread out to the neighbors with time, and was instantly extinguished in some area and then slowly resumed again. Such areal- spread FE did not occur for the CL-patterned sample, leading to the stable FE together with the instant turn-on capability. It is suggested that the spread FE and instability for the SL-patterned CNTs may be related to the electrical charging on the insulator surface around the cathode line edges.

• Journal of the Society of Naval Architects of Korea
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• v.42 no.4 s.142
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• pp.388-395
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• 2005

A numerical procedure is proposed as a mesh-size insensitive structural stress definition that gives a stress state at a weld toe with relatively large mesh size. The structural stress values obtained using different finite element types, i.e. shell element and solid element, are examined for typical weld structures. The calculation procedures are performed using the balanced nodal forces and moments obtained from finite element solutions. A consistent formulation based on work equivalent argument has been implemented to transform the balanced nodal forces and moments from shell to line force and line moments at each nodal position. The mesh-insensitivity, the effect of distance $\delta$(where the stress is calculated) and the potential limitations of the structural stress method are examined for various types of weldments. Based on the results from this study, it is expected to develop a more precise stress estimation technique for fatigue strength assessment of welded structures.

• Journal of Sensor Science and Technology
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• v.19 no.1
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• pp.25-30
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• 2010

This paper presents a low noise CMOS regulator for a low power capacitive sensor interface in a $0.5{\mu}m$ CMOS standard technology. Proposed LDO regulator circuit consist of a voltage reference block, an error amplifier and a new buffer between error amplifier and pass transistor for a good output stability. Conventional source follower buffer structure is simple, but has a narrow output swing and a low S/N ratio. In this paper, we use a 2-stage wide band OTA instead of source follower structure for a buffer. From SPICE simulation results, we got 0.8 % line regulation and 0.18 % load regulation.

• International Journal of Aeronautical and Space Sciences
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• v.13 no.3
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• pp.349-360
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• 2012

In this study, the accuracy of CSD (Comprehensive Structural Dynamics) analysis on the evaluation of blade aeroelastic responses and structural loads of HART(Higher harmonic Aeroacoustic Rotor Test) II baseline rotor is assessed using a comprehensive rotorcraft dynamics code, CAMRAD II, and a nonlinear flexible multi-body dynamics analysis code, DYMORE. Considering insufficient measurement data for HART II rotor, prescribed airloads computed by a three-dimensional compressible flow solver KFLOW are used to replace the lifting-line airloads and thereby enhance the prediction capability of the comprehensive analyses. The CSD results on blade elastic deflections using the prescribed airloads indicate more oscillatory behavior than those by lifting-line based approaches, but the wave pattern becomes improved by including artificial damping into the rotor system. It is demonstrated that the structural load predictions are improved significantly by the prescribed airloads approach against the measured data, as compared with an isolated CSD analysis.

• Journal of Microbiology and Biotechnology
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• v.11 no.6
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• pp.1055-1060
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• 2001

Experimental data for the on-line estimation of cell concentration and growth rate are presented. For this purpose, we utilized the on-line calculation of the oxygen uptake rate (OUR), which was derived from a liquid phase dynamic mass balance for the oxygen during the active growth phase in cyclosporin A (CyA) fermentation. The cell yield coefficient, based on the oxygen $(Y_{x/o})$for both suspended and immobilized cells of Tolypocladium inflatum, was estimated as $1.9 gDCW/gO_2$ from a very good linear correlation between the cell mass produced and the total oxygen consumed. The calculated yield showed a good agreement with the value of $(Y_{x/o})$ generated from the correlation between the cell growth rate and the oxygen uptake rate. In addition, further experimental data are given, which were also applied to determine the specific oxygen uptake rate of T. inflatum cells during the exponential phase of CyA fermentation. A theoretical basis for the analysis of these fermentation parameters is also provided.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.6
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• pp.2753-2758
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• 2012

Rubia cordifolia Linn, which belongs to the Rubiaceae family, is a well-known herb used in Ayurvedic medicine. In the present study, we investigated the influence of a methanolic extract (RC) on the induction of apoptosis in HEp-2 (human laryngeal carcinoma) cell line, as evidenced by cytotoxicity, morphological changes and modification in the levels of pro-oxidants. Inhibition of cell proliferation and lactate dehydrogenase (LDH) release increased in a time and dose-dependent manner. Further, reduced glutathione (GSH), glutathione transferase (GST) and protein levels decreased and lipid peroxidation increased significantly on RC treatment in a dose dependent manner when compared to controls. Based on the results we determined the optimal dose as 30mg/ ml and the apoptotic effect of RC extract (30 mg/ml) on HEp-2 cells was confirmed by fluorescent microscopy and transmission electron microscopy (TEM) based on morphological and ultrastructural changes. RC extract suppressed the proliferation of HEp-2 oral cancer cells inducing apoptotic cell death in vitro. These results point to potential of RC extract as an agent for the treatment of laryngeal squamous cell carcinoma.

• Proceedings of the Korean Society of Applied Pharmacology
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• 1994.11a
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• pp.147-172
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• 1994

Aziridinylbenzoquinones such as 3, 6-diaziridinyl-1, 4-benzoquinone (DZQ) and its 2, 5-methyl analog (MeDZQ) require bioreductive activation in order to elicit their anticancer activities. To determine the involvement of DTD in the activation of these drugs, we have used a ligation-mediated polymerase chain reaction to map the intracellular alkylation sites in a sing1e copy gene at the nucleotide level. We have performed this analysis in two human colon carcinoma cells, one proficient (HT-29) and one deficient (BE) in DT-diaphorase (DTD) activity. In the DTD proficient HT-29 cell line, DZQ and MeDZQ were found to alkylate both 5'-(A/T)G(C)-3' and 5'-(A/T)A-3' sequences. This is consistent with the nucleotide preferences observed when DZQ and MeDZQ are activated by purified DTD to reactive metabolites capable of alkylating DNA in vitro [Lee, C. -S., Hartley, J. A., Berardini, M. D., Butler, J., Siegel., D., Ross, D., & Gibson, N. W. (1992) Biochemistry, 31: 3019-3025]. Surprisingly in the DTD-deficient BE cell line a pattern of alkylation induced by DZQ and MeDZQ similar to that observed in the DTD-proficient HT-29 cells was observed. This suggests that reductive enzymes other than DTD can be involved in activating DZQ and MeDZQ to DNA reactive species in vivo.

• The Bulletin of The Korean Astronomical Society
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• v.42 no.1
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• pp.51.3-51.3
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• 2017

To investigate the connection between radio activity and AGN outflows, we present a study of ionized gas kinematics by using [O III] ${\lambda}5007$ emission line along the radio jet for six radio AGNs. These AGNs are selected based on the radioactivity (L1.4GHz ${\geq}$ 1039.8 erg s-1) as well as optical properties as type 2 AGNs. By using the high spatial resolution of the Red Channel Cross Dispersed Echellette Spectrograph at the Multiple Mirror Telescope, we investigate in detail the [O III] and stellar kinematics. We spatially resolve and probe the central AGN-photoionization sizes, which is important in understanding the structures and evolutions of galaxies. We find that the typical central AGN-photoionization sizes of our targets are in range of 1.8-3.8 kpc. We study the [O III] kinematics along the radio jets to test whether there is a link between gas outflows in the narrow-line region and radio jet emissions. Contrary to our expectation, we find no evidence that the gas outflows are directly connected to radio jet emission.

• International Journal of Reliability and Applications
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• v.11 no.2
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• pp.107-122
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• 2010

This paper deals with the reliability analysis of a complex system, which consists of two subsystems A and B connected in series. Subsystem A has only one unit and B has two units $B_1$ and $B_2$. Marked process has been applied to model the complex system. Present reliability model incorporated two repairmen: supervisor and novice to repair the failed units. Supervisor is always there and the novice remains in vacation and is called for repair as per demand. The repair rates for supervisor and novice follow general and exponential distributions respectively and the failure time for both the subsystems follows exponential distribution. The model is analyzed under "Head of line repair discipline". By employing supplementary variable technique, Laplace transformation and Gumbel-Hougaard family of copula various transition state probabilities, reliability, availability and cost analysis have been obtained along with the steady state behaviour of the system. At the end some special cases of the system have been taken.

• Proceedings of the Korean Society for Technology of Plasticity Conference
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• 2007.10a
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• pp.364-367
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• 2007

In nano-imprint lithography (NIL) process, which has shown to be a good method to fabricate polymeric patterns, several kinds of pattern defects due to thermal effects during polymer flow and mold release operation have been reported. A typical defect in NIL process with high aspect ratio and low resist thickness pattern is a resist fracture during the mold release operation. It seems due to interfacial adhesion between polymer and mold. However, in the present investigation, FEM simulation of NIL molding process was carried out to predict the defects of the polymer pattern and to optimize the process by FEA. The embossing operation in NIL process was investigated in detail by FEM. From the analytical results, it was found that the lateral flow of polymer resin and the applied pressure in the embossing operation induce the weld line and the drastic lateral strain at the edge of pattern. It was also shown that the low polymer-thickness result in the delamination of polymer from the substrate. It seems that the above phenomena cause the defects of the final polymer pattern. To reduce the defect, it is important to check the initial resin thickness.