• Title/Summary/Keyword: S-GPT

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A Study on the Chemical Constituents of Acanthopanax koreanum Nakai and Its Pharmaco-biological Activities (Acanthopanax koreanum Nakai의 약효성분에 관한 연구)

  • 한덕룡;김창종;김정희
    • YAKHAK HOEJI
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    • v.29 no.6
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    • pp.357-361
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    • 1985
  • Two glycosides, assumed to be one of the potential active principles, is isolate from the root bark of Acanthopanax koreanu Nakai, identified to be acanthoside D, $C_{34}H_{46}O_{18}$, mp $242^{\circ}C$, and syringo side, $C_{17}H_{24}O_{9}$ mp $192^{\circ}C$. Acanthoside D has been found to have s-GPT, s-GOT lowering effect, BSP-retention rate and survival rate in the toxic state through the bio-pharmacological experiments.

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A Case Report on Hepatic Abscess in a Grant′s Zebra (얼룩말에 있어서 Streptococcus equi에 의한 간농양 발생 1례)

  • Shin Nam-Sik;Kwon Soo-Wahn;Han Duk-Hwan
    • Journal of Veterinary Clinics
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    • v.10 no.1
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    • pp.131-135
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    • 1993
  • In this case, Grant's Zebra which had been bred and exhibited in Farmland Zoological Garden for 4 years, died after treated dystocia. Result in autopsy, she had large hepatic abscess, and blood chemistry were increased G07, GPT and total billirubin. The microbiological culture with the hepatic abscess idetified the Streptococcus equi. It is diagnosed of hepatic abscess which was caused by Streptococcus equi infection.

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Antidiabetic activity of Cultivated Cordyceps pruinosa

  • Kim, Tae-Woong;Sung, Jae-Mo;Yang, Ki-Sook
    • Proceedings of the PSK Conference
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    • 2003.10b
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    • pp.209.3-209.3
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    • 2003
  • Cordyceps species has been used as antiinflammatory, antitoxic, diuretic in folk remedies. Recent research has been reported the effect of anticancer, antidiabetic, antimutagenic, antilipid peroxidation. We examined the antidiabetic activity of cultivated Cordyceps pruinosa on streptozotocin-induced diabetic rats. The blood glucose level was recovered by treatment with Cordyceps pruinosa ethanol extract. The contents of GPT, total cholesterol and xanthine oxidase, glutathione peroxidase, catalase activities of the cytosol were significantly decreased as compared to the diabetic group. (omitted)

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The Serum and Immunohistochemical Analysis on the Anti-infammatory Effect of Aqueous Extract from Artemisia capillaris in the Liver of Lipopolysaccharide-injected Rat (인진추출물이 lipopolysaccharide주입에 의한 흰쥐 간의 염증반응에 미치는 혈청학적 및 면역조직화학적 영향)

  • 길영기;이준혁;최병태
    • Journal of Life Science
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    • v.14 no.2
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    • pp.215-220
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    • 2004
  • We investigated the anti-inflammatory effects of aqueous extract of Artemisia capillaris Thunb. (AEAC), a traditional Korean herb for remedying liver disease, for suppression in the process of lipopolysaccharide (LPS)-induced inflammation in the liver of rat. Level of glutamate oxaloacetate transaminase (GOT), glutamate pyruvate transaminase (GPT) and lactate dehydrogenase (LDH) was increased in the serum of LPS-treated rats compared to normal, however, in the rats pretreated with AEAC, the increase of GOT, GPT and LDH value was arrested. More severe histological changes of liver such as cloudy swelling, hydropic degeneration, Kupffer cell reaction and inflammatory cells infiltration were demonstrated in the rats challenged with LPS compared with normal. Fewer scores of these changes were observed in rats pretreated with AEAC. Immunohistochemical analysis showed that while the expression of the nuclear factor (NF)-kBp65, inducible nitric oxide synthase (iNOS), tumor necrosis factor (TNF)-$\alpha$ and COX (cyclooxygenase)-2 tended to increase, that of inhibitory (I)-kBa was decreased in the hepatocytes of rats challenged with LPS. A slight decline of NF-kBp65, TNF-$\alpha$ and COX-2, but increase of I-kB$\alpha$ were observed in the hepatocytes of the rats pretreated with AEAC. These results suggest that AEAC may act as a therapeutic agent for liver disease through a regulation of inflammation-related proteins.

Reduction of Cadmium Poisoning by Polyphenol Compounds Prepared from Persimmon Leaves (Diospyros kaki folium) (감나무 잎(Diospyros kaki folium)으로부터 분리한 Polyphenol 화합물이 카드뮴 중독 흰쥐의 피해경감 효과에 미치는 영향)

  • Jo, Guk-Young;Choi, Hee-Jin;Son, Jun-Ho;Bae, Du-Kyung;Woo, He-Sob;An, Bong-Jeon;Bae, Man-Jong;Choi, Cheong
    • Applied Biological Chemistry
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    • v.42 no.4
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    • pp.361-365
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    • 1999
  • In order to inspect safety and function regarding the reduction of cadmium poisoning by polyphenol compounds prepared from persimmon leaves (Diospyros kaki folium), animal test was done. Rats, group P-1 and P-2, were treated with cadmium and polyphenols of persimmon leaves. A control was just treated with cadmium. GOT activities in P-1 and in P-2 were lower than that of the control without considerable difference, whereas GPT activities decreased in P-1 and P-2. The SOD activity of liver tissue increased in P-l and P-2 compared with that of the control. GST activity was higher than that of the control without considerable difference in P-1; however, it increased in P-2. Lipid peroxide value considerably increased in both P-1 and P-2.

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Effects of Horticultural Occupational Therapy on the Physical and Psychological Rehabilitation of Patients with Hemiplegia after Stroke (반신마비 뇌졸중 환자의 심리와 정서적 재활에 대한 원예작업치료 효과)

  • Kim, Mi-Young;Kim, Gui-Soon;Mattson, Neil S.;Kim, Wan-Soon
    • Horticultural Science & Technology
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    • v.28 no.5
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    • pp.884-890
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    • 2010
  • To examine the effects of horticultural occupational therapy (HOT) on the physical and psychological rehabilitation of stroke patients with paralysis on one side of the body, a horticultural therapy (HT) program was implemented along with occupational therapy (OT) in 20 patients with hemiplegia after stroke (treatment group). In the control group, another 20 patients with hemiplegia after stroke received OT but no HT. The HOT program consisted of various indoor horticultural activities that proceeded stepwise on a weekly basis over the course of four weeks. The selected horticultural occupations were organized into four-phases: motivation, adaptation, sociality, and interpersonal relationships and communication. The grooved pegboard test (GPT), geriatric depression scale (GDS), and functional independent measure (FIM) were tested to the patients in this study. Unlike control group, the treatment group showed statistically significant differences in GPT, GDS, and FIM ($p$<0.001). In addition, communication, social cognition, and self-care scores as FIM subordinate factors were improved significantly by HOT program which motivated patients to engage in rehabilitation therapy. This finding suggests that HOT has the potential to be used as an OT program for stroke patients with hemiplegia.

Effects of Bisroot in the Diet on Growth, Body Composition, Immume responses of Nile Tilapia, Oreochromis niloticus (사료 중 비스루트가 나일틸라피아, Oreochromis niloticus의 성장, 체조성 및 면역 방응에 미치는 영향)

  • 김용화;오승용;황미혜;조재윤;박수일;김유희;윤길하;박정환
    • Journal of Aquaculture
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    • v.11 no.4
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    • pp.495-503
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    • 1998
  • The present study investigated the effects of Bisroot, that contains live bacteria (Bacillus polyfermenticus, Bacillus mesentericus, Streptococcus faecalis, & Bifidobacterium breve) and digestive enzymes (protease, lipase), on the growth, body composition and immune response of Nile tilapia fingerlings. One percent of the Bisroot was added to the experimenta feed. All exprimental fish were fed for 60 days. The weigh gains among the experimental fish were not significntly different (P>0.05). Hematocrit value, hemoglobin, total protein, glucose, GOT, and GPT were unaffected by Bisroot treatment. However, it was observed that glucose, GOT, and GPT value in the fish that were fed Bisroot, were lower than the control. The complement activity ($CH_50$) tended to be significantly increased by Bisroot treatment, but not lysozyme activity. Phagocytosis and respiratory burst activities of macrophages in the head kidney were enhanced by Bisroot. Therefore, the Bisroot diet enhances the cellular immune activities were enhanced by Bisroot. Therefore, the Bisroot diet enhances the cellular immune activities of non-specific immune responses. When fish were challenged with a virulent strain of Edwardsiella tarda, the Bisroot treated fish were more resistant than the control. The present results suggest that the introduction of Bisroot into the diet of Nile tilapia could increase their resistance against bacterial infection, reduce fish mortality, and offers economic benefits.

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The Effect of the Unsaturated Oil on the Normal Liver and Lipid Metabolism of Rats Fed Several Plant Oils (불포화도가 다른 식물성 유지를 섭취시킨 흰쥐에서 정상적 간 및 지질대사변화의 고찰)

  • 서화중;김선희;정두례
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.20 no.5
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    • pp.426-432
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    • 1991
  • To investigate the effect of the unsaturated plant oil on the normal liver and lipid metabalism rats were fed the daily dose of 1.57ml/kg body weight of perilla oil (Iodine value 190~207), corn oil (Iodine value 115~130) and olive oil (Iodine value 80~85) respectively for 28 days. The results were as follows. For the 14 days the test groups showed normal weight gain with 7.86~20.89% increase rate. In the period of the 3rd and the 4th week the increase rate of the perilla oil group was decreased significantly under 17.53~13.8% of control level, but the remainders(corn oil, olive oil) keep normal. The feeding of corn and olive oil for 28 days did show any harmful effect on normal GOT, GPT activity, ALK-P, serum cholesterol and serum triglyceride value of rat. The perilla oil feeding for 21~28 days slightly increased the GOT, GPT activity as 174.87, 93.46u but decreased the cholesterol and triglycerids value as 54.6~0.36mg/dl compared to control. In the pathological finding of test group liver some rats in 28 days feeding group showed reactive vesicula nuclei in corn oil group and mild fatty metamorphosis in olive oil group. But most subjects did not show any characterized sign of acute or subacute liver damage.

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Comparing Corporate and Public ESG Perceptions Using Text Mining and ChatGPT Analysis: Based on Sustainability Reports and Social Media (텍스트마이닝과 ChatGPT 분석을 활용한 기업과 대중의 ESG 인식 비교: 지속가능경영보고서와 소셜미디어를 기반으로)

  • Jae-Hoon Choi;Sung-Byung Yang;Sang-Hyeak Yoon
    • Journal of Intelligence and Information Systems
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    • v.29 no.4
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    • pp.347-373
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    • 2023
  • As the significance of ESG (Environmental, Social, and Governance) management amplifies in driving sustainable growth, this study delves into and compares ESG trends and interrelationships from both corporate and societal viewpoints. Employing a combination of Latent Dirichlet Allocation Topic Modeling (LDA) and Semantic Network Analysis, we analyzed sustainability reports alongside corresponding social media datasets. Additionally, an in-depth examination of social media content was conducted using Joint Sentiment Topic Modeling (JST), further enriched by Semantic Network Analysis (SNA). Complementing text mining analysis with the assistance of ChatGPT, this study identified 25 different ESG topics. It highlighted differences between companies aiming to avoid risks and build trust, and the general public's diverse concerns like investment options and working conditions. Key terms like 'greenwashing,' 'serious accidents,' and 'boycotts' show that many people doubt how companies handle ESG issues. The findings from this study set the foundation for a plan that serves key ESG groups, including businesses, government agencies, customers, and investors. This study also provide to guide the creation of more trustworthy and effective ESG strategies, helping to direct the discussion on ESG effectiveness.

Development and mathematical performance analysis of custom GPTs-Based chatbots (GPTs 기반 문제해결 맞춤형 챗봇 제작 및 수학적 성능 분석)

  • Kwon, Misun
    • Education of Primary School Mathematics
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    • v.27 no.3
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    • pp.303-320
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    • 2024
  • This study presents the development and performance evaluation of a custom GPT-based chatbot tailored to provide solutions following Polya's problem-solving stages. A beta version of the chatbot was initially deployed to assess its mathematical capabilities, followed by iterative error identification and correction, leading to the final version. The completed chatbot demonstrated an accuracy rate of approximately 89.0%, correctly solving an average of 57.8 out of 65 image-based problems from a 6th-grade elementary mathematics textbook, reflecting a 4 percentage point improvement over the beta version. For a subset of 50 problems, where images were not critical for problem resolution, the chatbot achieved an accuracy rate of approximately 91.0%, solving an average of 45.5 problems correctly. Predominant errors included problem recognition issues, particularly with complex or poorly recognizable images, along with concept confusion and comprehension errors. The custom chatbot exhibited superior mathematical performance compared to the general-purpose ChatGPT. Additionally, its solution process can be adapted to various grade levels, facilitating personalized student instruction. The ease of chatbot creation and customization underscores its potential for diverse applications in mathematics education, such as individualized teacher support and personalized student guidance.