• 디지털융복합연구
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• 제14권11호
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• pp.333-345
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• 2016

이 연구의 목적은 간호사의 DISC성격유형, 자기효능감, 임상수행능력사이의 관계를 규명하기 위함이다. 자료는 K시의 5개 병원에 근무하는 302명의 간호사로부터 수집하였다. 기술통계, t-test, ANOVA, 피어슨 상관관계 분석을 이용하여 분석하였다. 자기효능감과 임상수행능력은 D형이 I형과 S형보다 더 높음을 나타냈다. 임상수행능력의 하위 영역에서는 간호과정, 간호기술, 전문직발전에서 D유형이 S유형보다 높았고, 자기효능감에서도 D유형이 I유형과 S유형보다 높았다. DISC 유형별 자기효능감과 임상수행능력은 I 유형 (r = .66, p<.01), S 유형 (r = .60, p<. 01), D유형(r =.56, p<.01), C 유형 (r = .52, p<.01)으로 양의 상관관계를 나타냈다. D유형에서 대인관계/의사소통이 가장 낮은 상관관계를 보였으며, I유형과 S유형에서는 교육/협력관계가 가장 낮았다. C유형에서는 간호기술이 가장 높고, 간호과정이 가장 낮았다. 본 연구결과를 특성별 교육 프로그램이나 간호사 부서 배치에 활용한다면 효과적인 업무수행 결과를 가져올 수 있으리라 사료된다.

• 생약학회지
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• 제28권2호
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• pp.88-92
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• 1997

The full NMR assignment of hispidulin 7-0-neohesperidoside (1) isolated from Cirsium japonicum var. ussuriense was made with the aid of 2D correlation NMR techniques such as HMQC and HMBC. To investigate detoxification of bromobenzene-induced hepatic lipid peroxidation by compound 1, hepatic lipid peroxide level and the activities of enzymes responsible for production and removal of epoxide were studied. The level of lipid peroxide elevated by bromobenzene was significantly reduced by compound 1. This compound administered daily over one week before intoxication with bromobenzene did not affect the activities of aminopyrine N-demethylase, aniline hydroxylase, glutathione S-transferase. Epoxide hydrolase activity was decreased significantly by bromobenzene, which was restored to the control level by pretreatment of persicarin. The results suggest that the bromobenzene-induced hepatic lipid peroxidation by compound 1 is reduced by enhancing the activity of epoxide hydrolase, an enzyme removing bromobenzene epoxide.

• 한국수자원학회논문집
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• 제48권11호
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• pp.945-955
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• 2015

The technology of the SWG (Smart Water Grid) as one of most important national projects results in significant assignment that is closely associated with systematic management and effective operation. The individual component technics are required to establish directory and classification for the purpose of effectively managing their information related to research and development (R&D). The national science technology (S&T) standard classification tree which results in the representative example has been established with an intention to manage R&D information, human resource, and budget. It has been also revised every five years and then used in the various fields related to the evaluation, administration, and prediction of the national R&D projects. In addition, the standard classification system for R&D projects has been widely used in the UNESCO (United Nations Educational, Scientific and Cultural Organization) and EU (European Union) since the Frascati Manual was established in the Organization for Economic Cooperation and Development (OECD). Therefore, it is necessary for SWG techniques to develop the standard S&T classification tree for research management and evaluation. For this, it is essential to draw the core techniques for the SWG, which are incorporated with IT (Information Technology), NT (Nano Technology), and BT (Biology Technology).

• 대한원격탐사학회지
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• 제21권2호
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• pp.145-162
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• 2005

SAR 자료의 분류에서 토지 피복 구분 분류 정확도의 향상을 위해 이 논문은 다중 시기 SAR 자료를 이용한 분류에서의 특징 추출과 정보 융합 방법론을 제시하였다. 다중 시기 SAR 센서의 산란 특성을 고려하여 평균 후방 산란계수, 시간적 변이도와 긴밀도를 특징으로서 추출하였다. 이렇게 추출된 특징의 효율적인 응합을 위해 Dempster-Shafer theory of evidence(D-S 이론)와 퍼지 논리를 적용하였다. 특히 D-S 이론의 적용시 특징 기반 mass function 할당을 제안하였고, 퍼지 논리의 적용시 다양한 퍼지 결합 연산자의 결과를 비교하였다. 다중 시기 Radarsat-1 자료에의 적용 결과, 추출된 특징들은 서로 상호 보완적인 정보를 제공할 수 있으며 수계, 논과 도심지를 효율적으로 구분할 수 있었다. 그러나 산림과 밭은 구분이 애매한 경우가 나타났다. 정보 융합 방법론 측면에서, D-S 이론과 퍼지 Max와 Algebraic Sum 연산자를 제외한 다른 퍼지 연산자는 서로 유사한 분류 정확도를 나타내었다.

• 대한전기학회:학술대회논문집
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• 대한전기학회 1997년도 하계학술대회 논문집 D
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• pp.891-893
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• 1997

In this paper an intelligent power transformer protective relaying algorithm based on Fuzzy Decision-Making is presented. The introduced protection algorithm contains several internal fuzzy rule-bases including bpa(Basic Probability Assignment: m) which are subject to off-line pre-installation by the analysis of the transformer transient characteristics for detecting the internal fault. Dempster-Shafer's rule of combination is used for the inference method with rules to decide the situation of a transformer, The proposed algorithm immunes to the saturation of transformer, inrush conditions, over excitation, and external fault. The included results of testing show practically sufficient sensitivity and selectivity of the proposed algorithm.

• Asian Pacific Journal of Cancer Prevention
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• 제14권12호
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• pp.7473-7482
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• 2013

The G-protein coupled receptor 87 (GPR87) is a recently discovered orphan GPCR which means that the search of their endogenous ligands has been a novel challenge. GPR87 has been shown to be overexpressed in squamous cell carcinomas (SCCs) or adenocarcinomas in lungs and bladder. The 3D structure of GPR87 was here modeled using two templates (2VT4 and 2ZIY) by a threading method. Functional assignment of GPR87 by SVM revealed that along with transporter activity, various novel functions were predicted. The 3D structure was further validated by comparison with structural features of the templates through Verify-3D, ProSA and ERRAT for determining correct stereochemical parameters. The resulting model was evaluated by Ramachandran plot and good 3D structure compatibility was evidenced by DOPE score. Molecular dynamics simulation and solvation of protein were studied through explicit spherical boundaries with a harmonic restraint membrane water system. A DRY-motif (Asp-Arg-Tyr sequence) was found at the end of transmembrane helix3, where GPCR binds and thus activation of signals is transduced. In a search for better inhibitors of GPR87, in silico modification of some substrate ligands was carried out to form polar interactions with Arg115 and Lys296. Thus, this study provides early insights into the structure of a major drug target for SCCs.

• Bulletin of the Korean Chemical Society
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• 제35권5호
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• pp.1422-1432
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• 2014

Convergent all-electron multi-reference configuration-interaction (MRCI) calculations are performed for a lithium dimer with Kaufmann's Rydberg basis functions. A comparison of the results of these calculations with those of the effective core potential/core polarization potential (ECP/CPP) method and experimental data reveals the deficiency of the all-electron ab initio method. The deficiency is related to the mere 51.9% attainment of electron correlation for the ground state. The percent attainment of electron correlation for the first excited state is slightly better than that for the ground state, preventing us from obtaining better agreements with experimental data by means of increasing the size of basis sets. The Kaufmann basis functions are then used with the ECP/CPP method to obtain the accurate convergent potential energy curves for the $^1\prod_u$ states correlated to Li(2p) + Li(2p) and Li(2s) + Li(n = 2, 3, 4). Quantum defect curves (QDCs) calculated for both the $X^2\sum_g$ and 1 $^2\prod_u$ states of the $Li{_2}^+$ ion and the Lu-Fano plot reveal a strong series-series interaction between the two $2snp{\pi}$ and $2pnp{\pi}$ Rydberg series. The QDCs are then used to resolve assignment problems in the literature. The reassignments, performed by Jedrzejewski-Szemek et al., of the dissociation product of the D $^1\prod$ state from (2s+3d) to (2s+3p) and that of the 6 $^1\prod_u$ from (2s+4d) to (2s+4p) are found to be incorrect. It may be more natural to assign their $2snp{\pi}$ Rydberg series as a $2snd{\pi}$ series. The state, assigned as 5p $^1\prod_u$ by Ross et al. and 4d $^1\prod$ by Jedrzejewski-Szemek et al., is assigned as the 7 $^1\prod_u$ state, correlated to the Li(2s) + Li(4f) limit.

• 생약학회지
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• 제44권1호
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• pp.6-9
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• 2013

Two fraxinellone-based hydrogenated derivatives were prepared from fraxinellone, a well-known degraded limonin, via catalytic hydrogenation in the presence of $PtO_2$ in HOAc. Their structures were confirmed as (3S,3aR,3'R)-3a,7-dimethyl-3-(tetrahydrofuran-3-yl)-3a,4,5,6-tetrahydroisobenzofuran-1(3H)-one and (3S,3aR,2'R)-3-((R)-1-hydroxybutan-2-yl)-3a,7-dimethyl-3a,4,5,6-tetrahydroisobenzofuran-1(3H)-one on the basis of 2D NMR assignments. The $^{13}C$ NMR assignments of two quaternary carbons in the ${\alpha}$,${\beta}$-unsaturated carbonyl moiety of ${\gamma}$-butyrolactone core of fraxinellone should be revised.

• 한국화재소방학회:학술대회논문집
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• 한국화재소방학회 2011년도 추계학술논문발표회 논문집
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• pp.135-138
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• 2011

최근 국내의 경우 FDS를 이용한 성능설계, 화재영향평가 및 피난안전성평가등 다양한 분야에서 활발하게 사용되고 있으며 더불어 제조물책임법(PL법)과 실화책임에 대한 법률등이 새롭게 제정됨에 따라 화재조사 및 감정분야에 화재시물레이션이 적용될것으로 예상됨으로서 이러한 분야에 대한 화재시물레이션의 적용이 큰 이슈로 등장하고 있으며 이에 따라 소방방재청에서도 차세대소방기술에 대한 R&D로서 수행중에 있다. 본 연구는 이러한 상황에서 FDS를 화재조사에 활용함에 따른 문제점과 개선대책을 검토한 것이다.

• Applied Biological Chemistry
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• 제38권2호
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• pp.184-189
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• 1995

인삼의 다이올계 조사포닌 분획으로 부터 및 단계의 화학반응을 이용하여 (20S)-ginsenoside $Rh_2$ 및 그 입체이성체인 (20R)-ginsenoside $Rh_2$를 제조하였다. 또한 DEPT, $^1H-^1H$ COSY, HMQC, HMBC 및 NOESY와 같은 NMR 기법을 이용하여 두 화합물의 $^1H-NMR$과 $^{13}C-NMR$의 signal들을 완전히 동정하였다.