• Asian Pacific Journal of Cancer Prevention
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• 제17권7호
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• pp.3123-3129
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• 2016

Background: Cancer is the fourth leading cause of death in Sabah Malaysia with a reported age-standardized incidence rate was 104.9 per 100,000 in 2007. The incidence rate depends on non-mandatory notification in the registry. Under-reporting will provide the false picture of cancer control program effectiveness. The present study was to evaluate the performance of the cancer registry system in terms of representativeness, data quality, simplicity, acceptability and timeliness and provision of recommendations for improvement. Materials and Methods: The evaluation was conducted among key informants in the National Cancer Registry (NCR) and reporting facilities from Feb-May 2012 and was based on US CDC guidelines. Representativeness was assessed by matching cancer case in the Health Information System (HIS) and state pathology records with those in NCR. Data quality was measured through case finding and re-abstracting of medical records by independent auditors. The re-abstracting portion comprised 15 data items. Self-administered questionnaires were used to assess simplicity and acceptability. Timeliness was measured from date of diagnosis to date of notification received and data dissemination. Results: Of 4613 cancer cases reported in HIS, 83.3% were matched with cancer registry. In the state pathology centre, 99.8% was notified to registry. Duplication of notification was 3%. Data completeness calculated for 104 samples was 63.4%. Registrars perceived simplicity in coding diagnosis as moderate. Notification process was moderately acceptable. Median duration of interval 1 was 5.7 months. Conclusions: The performances of registry's attributes are fairly positive in terms of simplicity, case reporting sensitivity, and predictive value positive. It is moderately acceptable, data completeness and inflexible. The usefulness of registry is the area of concern to achieve registry objectives. Timeliness of reporting is within international standard, whereas timeliness to data dissemination was longer up to 4 years. Integration between existing HIS and national registration department will improve data quality.

• Journal of Periodontal and Implant Science
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• 제32권3호
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• pp.577-588
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• 2002

Osseointegrated implants have been established as the standard treatment modality for full/partial edentulous patients since the 1960's, and the long term results for full edentulous patients have proven to be successful. Based on these results osseointegrated implants are now widely used for partial edentulous patients. There has been an increased interest towards the efficacy of wide implants, despite many reports mentioning the lower success rate of wide implants compared to regular implants. Recently, mandibular molar area defects are commonly restored using 2 wide implants, but it is not determined whether which treatment modality-3 regular implants or 2 wide implants-shows superior success rate. In this study, 2 wide implants and 3 regular implants used for the restoration of mandibular molar area are used to compare the survival rate of 1-4 years, and to analyze and compare the failure factors. The following conclusions could be drawn from this study. 1. Wide implants and regular implants showed 94.5% and 97,6% of survival rate respectively. After prosthodontic work, the survival rate was 100% and 98.1% for wide implants and regular implants respectively. 2. 5 failed implants have been removed. 2 wide implants and 1 regular implant have been removed due to failure of osseointegration. 1 wide implant was removed due to abscess formation caused by over-heating, and 1 regular implant was removed due to mechanical failure caused by over-loading within the first year of function. 3. No statistically significant difference was observed with respect to the amount of marginal bone loss of wide and regular implants.(P>0.05) In conclusion, restoration of the mandibular molar area using 3 regular implants was found to be a good treatment modality, and 2 wide implants could he considered a good treatment modality when success factors are taken into account.

• Journal of Preventive Medicine and Public Health
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• 제36권2호
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• pp.101-107
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• 2003

Objectives : Dementia has emerged as a leading public health problem in elderly persons, and its early detection is important for the treatment of curable cases, and in the educational support for other family members. Although dementia screening tests are available, they have not gained widespread use in community or primary care settings. Our goal was to validate the Tine and Change (T&C) Test, -including its validity and reliability in patients, and to assess it as a simple, standardized method for the screening of dementia in the rural elderly. Methods : The participants in this study comprised of 59 patients from an urban hospital and 405 persons from a rural community aged 65 years or older. The time test evaluated the understanding of clock hands indicating 11:10, and the change test the ability to make 1,000 Won from a group of coins, consisting of one 500, seven 100, and seven 50 Won coins. The T&C ratings were validated against a reference standard based on the physician's diagnosis of the patients. The convergent validity in relation to other cognitive measure, test-retest agreement, and inter-observer reliability were assessed. To assess the relationship between the Korean Mini-Mental State Exam (K-MMSE) and the T&C Test, the mean K-MMSE scores were compared with the results of the T&C Test in the elderly from a rural community. Results The T&C Test had a sensitivity and specificity of 73.0, and 90.9%, and positive and negative predictive values of 93.1, and 66.7%, respectively. The test-retest and inter-observer agreement rates were both 95%. The K-MMSE scores and T&C Test were significantly related in the elderly from a rural community (p<0.01), The T&C Test was not influenced by the educational status. The Time and Change Tests took a mean of 6.3 and 12.7 seconds, respectively, to complete Conclusion : The T&C Test is a simple, accurate and reliable, performance-based tool in the screening for dementia. Because it is quick, and easy-to-use, it is hoped the T&C Test will be used for the widespread cognitive screening of aging populations.

• 한국식품과학회지
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• 제45권4호
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• pp.409-415
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• 2013

국내 유통되는 감귤류 총 100건을 대상으로 LC-MS을 이용하여 감귤류에 대한 수확 후 처리 농약 잔류량을 조사하였다. 보다 효율적인 농약 분석을 위해 LC-MS를 이용하여 직선성, 정확성, 정밀성, 검출한계 및 정량한계로 분석법의 유효성 검증을 하였다. 상관계수($R^2$)는 0.999이상의 우수한 직선성을 보였고, 농약의 회수율은 80.2-98.3%였고, RSD는 0.48-3.93%로 우수한 재현성을 나타냈다. 검출한계는 0.002-0.008 mg/kg였고, 정량한계는 0.006-0.027 mg/kg였다. 확립된 분석법에 의해 분석한 결과 최고 잔류 수준은 carbendazim은 0.541 mg/kg, thiabendazole은 0.958 mg/kg, imazalil은 0.721 mg/kg, azoxystrobin은 0.052 mg/kg였다. 본 연구결과에서 나타난 수확 후 처리 살균제는 잔류허용기준(MRL) 이내에서 안전하게 관리되고 있으나, 농약의 잔류성을 줄이기 위한 지속적인 모니터링이 필요하다.

• 치위생과학회지
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• 제15권1호
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• pp.54-59
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• 2015

본 연구는 시중에 널리 사용되는 치과용 지르코니아 코어를 이용하여 서로 다른 형태의 지대치를 대상으로 작업모형을 제작한 후, 치과용 스캐너를 통해 3차원 디지털 모형을 전환한 데이터를 토대로 지르코니아 코어를 제작하였으며, 각 실험군별 변연 적합도를 측정하여 비교분석하고자 하였다. 이와 같은 결과로 형태가 다른 지대치가 CAD/CAM system으로 치과 보철물 제작 시 적합도의 영향여부를 비교하였다. 제한된 조건 하에서 수행된 본 연구에서 다름과 같은 결과를 보였다. 지대치의 형태가 다른 작업모형으로 제작된 지르코니아 코어의 변연 적합도는 큰 차이가 없었다(p>0.05). 작업모형의 부위를 4등분으로 나누어 측정한 변연 적합도 또한 통계적으로 유의한 차이를 보이지 않았다. 결론적으로 3종류의 다른 지대치 모두 유사한 지르코니아 코어의 변연 적합도를 보였으며, 측정된 결과는 선행연구에 비추어 볼 때 임상적으로 허용 가능한 수치($100{\sim}120{\mu}m$)를 초과하는 실험군은 없었다. 이와 같은 결과를 토대로 다른 형태의 지대치를 사용하여 제작되었더라도 지르코니아 코어의 변연 적합도에 큰 영향을 주지 않을 것으로 생각된다.

• 한국동물위생학회지
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• 제30권3호
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• pp.429-436
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• 2007

This study was performed to make helpful standard for discrimination of cows from heifers by uterine and ovarian section inspection. A total of 3,736 heifers and 249 cows were inspected from January to November 2006 in Karak Market Slaughter house. Firstly, it was obvious that non-corpus albicans were observed in almost heifers(3,597/3,736, 96.3%), but there were distinctive corpus albicans in all cows (249/249 100%). Secondly, another evident was that the length and diameter of the horn in uterus was below 30mm in 94.5% (3,267/3,736) heifers, but above 30mm in 90.4% (225/245) cows, and it was easy to distinguish between right and left horn by difference of size in 87.6% (218/249) cows. Thirdly the diameters of pelvic cavity was below 220mm in 96.8% (3,615/3,736) heifers, but was over 200mm in 85.1% (212/249) cows. Fourthly another difference was found in second sacrum union condition and 13th thoracic vertebral process's states. In case of heifers, it was distinctive five lines in each second sacrum, but it was non-distinctive or united in the same each lines of the sacrum in cows. Fifthly in the results of 13th thoracic vertebral colors, the ratio between red color and white color was 7 : 3 in heifers (3,385/3,736, 90.6%), but that was 2 : 8 in cows (199/249, 79.9%). Consequently, it was possible to use the method which discriminated cows from heifers by uterine and ovarian section inspection in large scaled field slaughter house.

• 대한전자공학회논문지
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• 제16권4호
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• pp.36-46
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• 1979

본 연구에서는 N -채널 실리콘 게이트 제작기술에 의하여 일련의 크기를 가지는 커페시터와 트렌지스터들이 제작되었다. 그 결과 다양한 이온 주입 조걸, 즉 B 의 경우 에너지 30keV∼60keV와 도오스 3 × 10 ~ 5 × 10 개/㎠ 그리고 P 의 경우 에너지 1001keV∼ 175keV와 4 ×10 ~ 7×11개/㎠ 도오스 영역에서 이들에 대한 D.C. 인자들의 측정치들이 이론적인 계산치들과 비상, 분석되어 있다. 이 D.C. 인자들에는 threshold전압, 공핍층의 폭, 게이트 산화물 두께, 표면상태, 가동 하전입자 밀도, 전자의 이동도 그리고 마지막으로 누설전류가 있는데, 이중 실제 MOS의 제작에 있어서 특허 중요한 threshold전압에 있어서는, 커어브트레이서와 C - V plot을 통하여 측정된 값들이 실제 재산에서 이용된 SUPREM II 컴퓨우터 프로그램에 의한 결과와 훌륭히 접근하고 있다. 그 밖에 여기나온 D.C.인자들 중에서 도오핑 수준은 기판의 역 게이트 바이어스에서 threshold전압들로 부터 계산된 것이고, 역전도는 정의된 subthreshold 기울기로 부터 추산된 것임을 밝혀 둔다. 마지막으로 이와같은 D. C. 시험 결과들을 종합적으로 평가해 볼 때 만들어진 커페시터와 트렌지스터들이 N -채널 MOS I. C. 기억소자용으로 적합함을 보여주고 있다.

• 한국동물위생학회지
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• 제34권4호
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• pp.321-331
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• 2011

Mycobacterium bovis, a member of the M. tuberculosis complex (MTC), is the causative agent of bovine tuberculosis. Detection of M. bovis and M. tuberculosis using conventional culture- and biochemical-based assays is time-consuming. Therefore, a simple and sensitive molecular assay for rapid detection would be of great help in specific situations such as faster diagnosis of bovine tuberculosis (bTB) infection in the abattoirs. We developed a novel multiplex real-time PCR assay which was applied directly to biological samples with evidence of bTB and it was allowed to differentiate between M. bovis and M. tuberculosis. The primers and TaqMan probes were designed to target the IS1081 gene, the multi-copy insertion element in the MTC and the 12.7-kb fragment which presents in M. tuberculosis, not in the M. bovis genome. The assay was optimized and validated by testing 10 species of mycobacteria including M. bovis and M. tuberculosis, and 10 other bacterial species such as Escherichia coli, and cattle lymph nodes (n=113). The tests identified 96.4% (27/28) as M. bovis from the MTC-positive bTB samples using conventional PCR for specific insertion elements IS1081. And MTC-negative bTB samples (n=85) were tested using conventional PCR and the real-time PCR. When comparative analyses were conducted on all bovine samples, using conventional PCR as the gold standard, the relative accuracy of real-time PCR was 99.1%, the relative specificity was 100%, and the agreement quotient (kappa) was 0.976. The detection limits of the real-time PCR assays for M. bovis and M. tuberculosis genomic DNA were 10 fg and 0.1 pg per PCR reaction, respectively. Consequently, this multiplex real-time PCR assay is a useful diagnotic tool for the identification of MTC and differentiation of M. bovis and M. tuberculosis, as well as the epidemiologic surveillance of animals slaughtered in abattoir.

• 재활간호학회지
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• 제4권1호
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• pp.31-45
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• 2001

The purpose of this study was to investigate the relationship between self-concept and self-care activities of the cerebral palsied adolescents and to gain the baseline data for development of effective rehabilitation nursing intervention program of the cerebral palsied adolescents. The design of this study was a descriptive correlational study. The subjects of the study were 160 cerebral palsied adolescents attending at special schools located in Seoul and Kyonggi and rehabilitation centers located in Seoul, Kyonggi and Kyongnam province. The data was collected from May 20 to July 20, 2000. The instrument used for this study were the self-concept scale(50items 4point scale) and self-care activities scale(29items 4point scale). Self-Concept Scale had developed by Fitt(1965), which was standardized by Chung(1968) and modified by Kim(1984). Self-Care Activities Scale developed by the researcher through out the consulting of expert and pilot study on the basis of ADL check list developed by Kang(1984) and LDSQ-3(Lambeth Disability Screening Questionnair-3) developed by Na et al. (1995). The data was analyzed by the SPSS/PC+program using frequency, percentage, mean, standard deviation, t-test, ANOVA & Scheffe test and Pearson's correlation coefficient. The results of this study were as follows; 1. The mean score of self-concept was $138.55{\pm}17.20$(range: 50-100), which the item mean score was $2.77{\pm}0.34$(range: 1-4). The score of subarea of the self-concept was the highest score in family self ($3.01{\pm}0.54$) and the lowest score in physical self ($2.52{\pm}0.42$). 2. The mean score of self-care activities was $95.25{\pm}21.69$ (range: 29-116), which the item mean score was $3.28{\pm}0.75$ (range: 1-4). The score of subarea of the self-care activities was the highest score in feeding($3.75{\pm}0.59$) and the lowest score in walking($2.64{\pm}1.21$). 3. There were statistically significant difference in the score of self-concept according to the age (F=3.24, P=.04), the grads (F=4.36, P=.01), and types of cerebral palsy (F=2.42, P=.03). 4. There were statistically significant difference in the score of self-care activities according to the age (F=8.29, P=.00), the grads (F=16.05, P=.00), types of living place (F=6.46, P=.00), types of cerebral palsy (F=48.92, P=.00), whether or not receiving a rehabilitation therapy (t=-3.64, P=.00), whether or not receiving a vocational training (t=2.14, P=.03), and whether or not using a device (t=-7.42, P=.00). 5. There was not significant correlation between self-concept and self-care activities (r=.081, P=.311).

• 한국항해항만학회지
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• 제36권5호
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• pp.401-407
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• 2012

본 연구는 요트관광산업 활성화를 위한 소비자의 요트관광 선호도와 활성화 방안에 대한 인식도 조사를 통해 요트관광 마케팅 전략수립과 보다 효과적인 요트관광 활성화 방안을 수립하는데 기초자료를 제공하기 위해 수행되었다. 이러한 연구목적을 달성하기 위해 본 연구에서는 B광역시 요트경기장과 해수욕장을 방문한 외부 방문객 및 시민 300명을 조사대상으로 선정해 현장에서 설문조사를 실시하여 다음과 같은 결론을 도출하였다. 첫째, 요트관광 상품 구매의사는 64%로 요트관광 수요는 낙관적이었으며, 지불가능 지출액은 일일기준 10만원 미만인 것으로 나타났다. 둘째, 소비자들의 요트관광에 대한 선호도는 요트체험 및 교육 중심 프로그램으로 주말이나 방학 및 휴가기간을 이용해 당일 또는 1박 2일 요트관광 상품을 선호하고 있었으며 요트관광의 목적은 여가 및 위락 그리고 선호 동행인은 가족 및 친구인 것으로 나타났다. 셋째, 소비자들의 요트관광 제약요인은 요트관광 비용, 시간소비형 관광활동 그리고 다양한 상품의 부재가 주요인이었으며, 선택요인은 관광비용, 연계관광 상품 그리고 요트관광 상품의 질인 것으로 파악되었다. 마지막으로 요트관광 활성화 방안 중에 요트관광 상품의 개발, 기반여건 조성 그리고 마케팅에 대한 중요성이 상대적으로 높게 나타났다.