• 대한한방소아과학회지
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• 제30권2호
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• pp.72-81
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• 2016

Objectives The purpose of this study is to understand the correlation between spleen deficiency syndrome, body mass index (BMI) and eating habit in children and adolescents and to provide foundation of preventive care and treatment. Methods A survey was conducted with 115 children and adolescents, who were 4th, 5th and 6th grade of elementary school in Gwangju from March 2nd, 2016 to April 8th, 2016. Body mass index (BMI) was calculated using the measured height and weight. Spleen deficiency syndrome and eating habit in children and adolescents were investigated by using the Deficiency of the Spleen Questionnaire and Korean Children's Eating Behaviour Questionnaire (K-CEBQ). A data analysis was performed by using SPSS 23.0 program. Results 1. There was no statistically significant correlation between spleen deficiency syndrome and body mass index (BMI). 2. Children and adolescents with spleen deficiency syndrome were interested in food rather than avoided it. 3. There was a positive correlation between body mass index (BMI) and FR (Food responsiveness), "Food approach". The correlation between the healthy weight group and FR is statistically significant negative correlation. Conclusions Due to various limitations, it is difficult to generalize the correlation between spleen deficiency syndrome, body mass index (BMI) and eating habit in children and adolescents. Therefore additional research is necessary to confirm this study's findings.

• 대한한의학회지
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• 제33권1호
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• pp.68-78
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• 2012

Objectives: The purpose of this study was to analyze the relationship between Yin-deficiency questionnaire score and various biofunctional signals in women. Methods: A retrospective chart review was performed on charts of 195 patients who visited Gangdong Kyung Hee Hospital between April 1st and September 30th, 2011. The subjects were categorized into two groups, a low Yin-deficiency group (n=118) and a high Yin-deficiency group (n=77). The authors analyzed the correlation between Yin-deficiency questionnaire score and biofunctional signals by Pearson's correlation coefficient test and the difference in biofunctional signals between the two groups by independent samples t-test using SPSS for windows. Results: 1. Negative correlations were observed between the temperature difference of back-humerus, standard deviation of all R-R intervals (SDNN), total power (TP), low frequency (LF), high frequency (HF) on heart rate variability parameters, and Yin-deficiency questionnaire score. A positive correlation was observed between the temperature difference of knee-humerus and Yin-deficiency questionnaire score. 2. The temperature difference of back-humerus in the high Yin-deficiency group was significantly higher than that in the low Yin-deficiency group. The temperature difference of knee-humerus, height, waist-hip ratio, SDNN, TP, LF, and HF of the high Yin-deficiency group were significantly lower than those of the low Yin-deficiency group. Conclusions: The results of this study suggest that the comprehensive diagnosis of Yin-deficiency and biofunctional signals is useful.

• 한국생활과학회지
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• 제12권4호
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• pp.403-416
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• 2003

The recent study was examined the effects of stress related to self-esteem upon the types of deficiency, the genders, the grades. A Questionnaire was distributed to 172 elementary school students in 4th, 5th and 6th grades. The results of this study were as follows : First, children's stresses were related to their self-esteem and their self-esteem was explained mostly by the stress from home environment. Second, children's stress upon the birth order was higher in the first than in the second and the third birth order. Third, their self-esteem was explained mostly by the support from friends, teachers, and academic fields. Forth, children's stress of divorced and separated families as a reason of deficiency was higher than their stress upon the separation by death.

• Journal of applied mathematics & informatics
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• 제29권3_4호
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• pp.949-953
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• 2011

It is interesting to know the behavior of a network from its structure. One interesting topic is to find a relation between the existence of a positive equilibrium of the reaction network and its structure. One approach to study this topic is using the concept of deficiency. Another is using some conditions on nodes, which can apply to large-size networks compared to deficiency. In this work, we show the relation between deficiency and the conditions.

• Nutrition Research and Practice
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• 제3권2호
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• pp.122-127
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• 2009

Folate is generally considered as a safe water-soluble vitamin for supplementation. However, we do not have enough information to confirm the potential effects and safety of folate supplementation and the interaction with vitamin $B_{12}$ deficiency. It has been hypothesized that a greater methyl group supply could lead to compensation for vitamin $B_{12}$ deficiency. On this basis, the present study was conducted to examine the effects of high-dose folic acid (FA) supplementation on biomarkers involved in the methionine cycle in vitamin $B_{12}$-deficient rats. Sprague-Dawley rats were fed diets containing either 0 or $100{\mu}g$ (daily dietary requirement) vitamin $B_{12}/kg$ diet with either 2 mg (daily dietary requirement) or 100 mg FA/kg diet for six weeks. Vitamin $B_{12}$-deficiency resulted in increased plasma homocysteine (p<0.01), which was normalized by dietary supplementation of high-dose FA (p<0.01). However, FA supplementation and vitamin $B_{12}$ deficiency did not alter hepatic and brain S-adenosylmethionine (SAM) and S-adenosylhomocysteine (SAH) concentrations and hepatic DNA methylation. These results indicated that supplementation of high-dose FA improved homocysteinemia in vitamin $B_{12}$-deficiency but did not change SAM and SAH, the main biomarkers of methylating reaction.

• Clinical and Experimental Reproductive Medicine
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• 제42권2호
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• pp.72-76
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• 2015

$17{\alpha}$-hydroxylase and 17,20-lyase are enzymes encoded by the CYP17A1 gene and are required for the synthesis of sex steroids and cortisol. In $17{\alpha}$-hydroxylase deficiency, there are low blood levels of estrogens, androgens, and cortisol, and resultant compensatory increases in adrenocorticotrophic hormone that stimulate the production of 11-deoxycorticosterone and corticosterone. In turn, the excessive levels of mineralocorticoids lead to volume expansion and hypertension. Females with $17{\alpha}$-hydroxylase deficiency are characterized by primary amenorrhea and delayed puberty, with accompanying hypertension. Affected males usually have female external genitalia, a blind vagina, and intra-abdominal testes. The treatment of this disorder is centered on glucocorticoid and sex steroid replacement. In patients with $17{\alpha}$-hydroxylase deficiency who are being raised as females, estrogen should be supplemented, while genetically female patients with a uterus should also receive progesterone supplementation. Here, we report a case of a 21-year-old female with $17{\alpha}$-hydroxylase deficiency who had received inadequate treatment for a prolonged period of time. We also include a brief review of the recent literature on this disorder.

• 한국초지조사료학회지
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• 제32권4호
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• pp.343-352
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• 2012

Sulphur deficiency has become widespread over the past several decades in most of the agricultural area. Oilseed rape (Brassica napus L.) is a very sensitive to S limitation which is becoming reduction of quality and productivity of forage. Few studies have assessed the sulphur mobilization in the source-sink relationship, very little is known about the regulatory mechanism in interaction between sulphur and nitrogen during the short-term sulphur deficiency. In this study, therefore, amount of sulphur and nitrogen incorporated into amino acids and proteins as affected by different S-supplied level (Control: 1 mM ${SO_4}^{2-}$, S-deficiency: 0.1 mM ${SO_4}^{2-}$, and S-deprivation: 0 mM ${SO_4}^{2-}$) were examined. The amount of sulphur in sulphate (S-sulphate) was significantly decreased by 25.8% in S-deprivation condition, compare to control, but not nitrogen in nitrate (N-nitrate). The markedly increase of sulphur and nitrogen incorporated amino acids (S-amino acids and N-amino acids) was observed in both S-deficiency and S-deprivation treatments. The amount of nitrogen incorporated proteins (N-protein) was strongly decreased as sulphur availability while the amount of sulphur incorporated into proteins (S-protein) was not affected. A highly significant ($p{\leq}0.001$) relationship between S-sulphate and S-amino acid was observed whereas the increase of N-amino acids is closely associated with decrease of N-proteins. These data indicate that increase of sulphur and nitrogen incorporated into amino acids was from different nitrogen and sulphur metabolites, respectively

• Pediatric Gastroenterology, Hepatology & Nutrition
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• 제12권sup1호
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• pp.46-52
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• 2009

As the most common nutrition deficiency, iron deficiency not only causes anemia but also influences the central nervous system development. Its pathogenesis is supposed to be the alteration of neurometabolism and neurotransmission in major brain structures, and the disruption of myelination. The first two years after birth is a crucial period for cognitive, behavior, and emotional development with fast brain growth. If iron deficiency occurs in this period, cognitive and psychomotor function cannot be restored in spite of adequate iron supplementation. Thus, iron deficiency in infancy should be considered as a serious disease.

• Asian-Australasian Journal of Animal Sciences
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• 제15권4호
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• pp.509-515
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• 2002

Copper deficiency was induced in eight male buffalo calves by adding molybdenum (30 ppm wet basis) to their diet. Copper status was monitored from the liver copper concentration and a level below 30 ppm (DM basis) was considered as deficient. Haemoglobin, haematocrit, total and differential leucocyte numbers were determined. The functions of peripheral neutrophils were assessed by in vitro phagocytosis and killing of Staphylococcus aureus. The effect of molybdenum induced copper deficiency on bone marrow was monitored. The mean total leucocyte count was unaffected whereas a significant fall in neutrophil count coincided with the fall in hepatic copper level to $23.9{\pm}2.69$ ppm. Reduced blood neutrophil numbers was not accompanied by any change in the proportion of different neutrophil precursor cells in bone marrow. It was hypothesised that buffalo calves were more tolerant to dietary molybdenum excess than cattle. It was concluded that neutropenia in molybdenum induced copper deficiency occurred without any effect on their synthesis and maturation process. Bone marrow studies in healthy calves revealed higher percentage of neutrophilic myelocytes and metamyelocytes as compared to cattle.

• 대한한의학원전학회지
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• 제23권1호
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• pp.91-100
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• 2010

In this study, I investigated physiology and pathology of the kidney and then researched deficiency of the kidney-nourishing the Eum music therapy to apply for clinical use, because symptoms such as chronic fatigue, morbus asthenia, anxiety, dizziness, tinnitus, and amnesia are prevalent in our modern societies. These symptoms are due to deficiency of the kidney. The kidney stores vital essence and has a function to keep activities as motive power. If the kidney is abnormal in storing the essence and holding Gi, various symptoms like dizziness, tinnitus, amnesia are caused by deficiency of the kidney. In deficiency of the kidney-nourishing the Eum music therapy, Water-Gi music which can store the essence is mainly used. In case of patients with deficiency of the kidney, dizziness, tinnitus, and amnesia, we can make use of NO.3, BWV 1068, Air of J.S.Bach and Jinyangjo of Geomungo. If there are flaring-up and fidgetiness due to deficiency of vital essence, Earth-Gi music that can help the vigor of spleen and stomach should be used prior to Water-Gi music. In the concrete, Hahyeondodeuri of Yeongsanhoesang played on Geomungo can be used. The tinnitus is caused by wind-heat and fire in the gallbladder. It is good to nourish the Eum through Water-Gi music after dispelling pathogens through Jajinmori among Gayageum sanjo.