• The Journal of the Society of Korean Medicine Diagnostics
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• v.20 no.1
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• pp.45-50
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• 2016

Objectives Although the word Zheng (證) is widely used basic term in nowaday's East Asian traditional medicine, it's definition can't be found in ancient texts before 20th century, and the history in which that term got general meaning in public, have not been clearly introduced. So the present author show the way Zheng confirm it's modern implication. Methods To search the books that contain any contents on Zheng's definition, the author mainly used the electronic texts of Super Star Reader (超星閱讀器). To search modern study article on Zheng's definition, the author used China National Knowledge Infrastructure (www.cnki.net). Results The present study shows that : although Treatments according to disease Pattern Identification (辨證施治) have been prominent treatment modality in East Asian traditional medicine, the general definition of disease Pattern (證) was given in late 20th century. Especially from 1955 to 1965, some major scholars like Ren Ying Qiu (任應秋), Zhu Yan (朱顔), Qin Bo Wei (秦伯未) and Jiang Jian Fu (蔣見復) did important roles in it's concept creation. Conclusions Modern concept of Zheng (證) was defined in late 20th century.

• Asian Pacific Journal of Cancer Prevention
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• v.17 no.3
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• pp.1141-1148
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• 2016

Background: A large number of studies have been published to investigate the association between the null genotype of glutathione S-transferase T1 (GSTT1) with gastric cancer. However, the results were inconsistent and conflicting. The aim of this study was to estimate the relationship between this polymorphism in the GSTT1 gene and gastric cancer risk in Asian populations by meta-analysis. Materials and Methods: A literature search was performed in PubMed, Embase, Chinese Biomedical database (CBM), Weipu database, Wanfang database, and China National Knowledge Infrastructure database (CNKI). Statistical analysis was conducted by using Review Manager 5.3. Results: Thirty-nine studies with a total of 7,737 gastric cancer cases and 10,823 controls were included in this meta-analysis. The meta-analysis of total studies showed that the null genotype in GSTT1 was associated with increased risk of gastric cancer in Asians (OR=1.19, 95% CI=1.08-1.31, p=0.0002). Subgroup analysis showed a significant relationship between GSTT1 null genotype and gastric cancer in East-Asians, as well as in subgroup analysis of hospital-based design. On subgroup analysis by smoking status, alcohol status, Helicobacter pylori infection status, and histology type, no significant association of this polymorphism with susceptibility to gastric cancer was found. Conclusions: In conclusion, the results showed that the null genotype of GSTT1 is significantly associated with an increased risk in gastric cancer in Asian populations.

• KIPS Transactions on Software and Data Engineering
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• v.4 no.4
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• pp.151-160
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• 2015

Internet-of-Things(IoT) is the computing environment to provide valuable services by interacting with multiple devices, where diverse devices are connected within the existing Internet infrastructure and acquire context information by sensing. As the concern of IoT has been increased recently, most of the industries develop many IoT devices. And, many people are focused on the IoT application that is utilizing different technologies, which are sensor network, communication technologies, and software engineering. Developing on-ground IoT application is especially even more active in progress depending on increasing of on-ground IoT devices because it is possible for them to access dangerous and inaccessible situation. However, There are a few studies related IoT. Moreover, since on-ground IoT application, which is different from typical software application, has to consider device's characteristics, communication, and surround condition, it reveal challenges, decreasing reliability. Therefore, in this paper, we analyze reliability challenges related to maturity and fault tolerance, one of reliability attributes, occurring in developing on-ground IoT applications and suggest the effective solutions to resolve the challenges. To verify proposed the challenges and solutions, we show result that is applying the solutions to applications. By presenting the case study, we evaluate the effectiveness of applying the solutions to the application.

• Journal of The Korean Society of Agricultural Engineers
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• v.48 no.7
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• pp.73-86
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• 2006

Concentrated poultry production in the State of Alabama, U.S.A. results in excessive poultry litter. Application of poultry litter to pastures and row crops serves as a cheap alternative to commercial fertilizer. However, over the years, poultry litter application to perennial forage crops in the Appalachian Plateau region of North Alabama has resulted in phosphorus (P) buildup in soils. Phosphorus index (P-index) and comprehensive nutrient management plans (CNMP) are often used as a best management practice (BMP) for proper land application of litter. Because nutrient management planning is often not done for small animal feeding operations (AFOs), and also because, in case of excess litter, litter transportation infrastructure has not been developed, over application of poultry litter to near by area is a common practice. To alleviate this problem, optimal poultry litter management and transportation infrastructure needs to be developed. This paper presents a methodology to optimize poultry litter application and transportation through efficient nutrient management planning and transportation network analysis. The goal was accomplished through implementation of three important modules, a P-Index module, a CNMP module, and a transportation network analysis module within ArcGIS, a Geographic Information System (GIS). The CNMP and P-Index modules assist with land application of poultry litter at a rate that is protective of water quality, while the transportation network analysis module helps transport excess litter to areas requiring litter in the Appalachian Plateau and Black Belt (a nutrient-deficient area) regions. Once fully developed and implemented, such a system will help alleviate water quality problems in the Appalachian Plateau region and poor soil fertility problems in the Black Belt region by optimizing land application and transportation. The utility of the methodology is illustrated through a hypothetical case study.

• Nuclear Engineering and Technology
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• v.50 no.6
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• pp.957-962
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• 2018

The gamma radiation shielding capability (GRSC) of two clay-materials (Ball clay and Kaolin)of Southwestern Nigeria ($7.49^{\circ}N$, $4.55^{\circ}E$) have been investigated by determine theoretically and experimentally the mass attenuation coefficient, ${\mu}/{\rho}(cm^2g^{-1})$ of the clay materials at photon energies of 609.31, 1120.29, 1173.20, 1238.11, 1332.50 and 1764.49 keV emitted from $^{214}Bi$ ore and $^{60}Co$ point source. The mass attenuation coefficients were theoretically evaluated using the elemental compositions of the clay-materials obtained by Particle-Induced X-ray Emission (PIXE) elemental analysis technique as input data for WinXCom software. While gamma ray transmission experiment using Hyper Pure Germanium (HPGe) spectrometer detector to experimentally determine the mass attenuation coefficients, ${\mu}/{\rho}(cm^2g^{-1})$ of the samples. The experimental results are in good agreement with the theoretical calculations of WinXCom software. Linear attenuation coefficient (${\mu}$), half value layer (HVL) and mean free path (MFP) were also evaluated using the obtained ${\mu}/{\rho}$ values for the investigated samples. The GRSC of the selected clay-materials have been compared with other studied shielding materials. The cognizance of various factors such as availability, thermo-chemical stability and water retaining ability by the clay-samples can be analyzed for efficacy of the material for their GRSC.

• Journal of Korea Technology Innovation Society
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• v.12 no.3
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• pp.638-661
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• 2009

With the advance to the knowledge-based economy, science and technology (S&T) has been recognized as key factor in a nation's competitiveness. To cope with this kind of new trend Korean government has tried to increase the R&D investment and to streamline acts and regulations concerning national R&D activities. Korea's total R&D expenditure for the year 2007 amounted to about 31.3 trillion won including government R&D of 8.9trillion won. With these efforts the capacity of Korea S&T has made great strides recently. Korea was ranked world's top 7 in R&D investment, top 12 in S&T paper publication and top 4 in patent application. Korean government enacted several pieces of legislation concerning S&T : the "Technology Transfer Promotion Act (1999)"; the "Framework Act on Science and Technology (2000)"; and the "Presidential Regulation for Managing the Government R&D Programs (2001)." In addition, the government has put a lot of effort into promoting the commercialization of technologies developed in public sector and improving the infrastructure of technology transfer and commercialization. However in spite of these various efforts, the technologies obtained from the public sector have not been transferred to the industry properly. Only 24.2% of technologies developed in the public for the year 2005 were transferred to industry. The royalty revenues of the public for the year 2005 was 1.5% of their total R&D expenditure. It shows only a third of the percentage of royalty revenues for the public sector in the U.S.A. and a second of Europe. There are many obstacles of public technology transfer such as immaturity of technology market, lack of licensing experience, and inadequacy of legal system and government policy. In this study I compared the Korean legislative system of patent management of government R&D outputs with the American system, derived problems from Korean system, and suggested proper alternatives.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.22
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• pp.9693-9698
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• 2014

Background: Associations between the 8473T>C polymorphism (rs5275) in the cyclooxygenase-2 (COX-2) gene and breast cancer (BC) risk are still inconclusive and ambiguous. The aim of this meta-analysis was to comprehensively estimate the genetic risk of 8473T>C polymorphism in the COX-2 gene for BC. Materials and Methods: We searched PubMed, Web of Science, Medline, Chinese biomedical (CBM), Weipu, China national knowledge infrastructure (CNKI), and Wanfang databases, covering all publications (last search was updated on Aug 17, 2014). Statistical analyses were performed using Revman 5.3 and STATA 10.0 software. Results: A total of 6,720 cases and 9,794 controls in 12 studies were included in this study. The results indicated no significant associations between the 8473T>C polymorphism of the COX-2 gene and BC risk for the CC+TC vs TT model (pooled odds ratio (OR)=0.97, 95% confidence interval (CI)=0.90-1.03, and p=0.29). On subgroup analysis, we also found that subdivision on ethnicity among Caucasians, Asians and others also revealed no relationship with BC susceptibility. With the study design (CC+TC vs TT), no significant associations were found in either population-based case-control studies (PCC), or hospital-based case-control studies (HCC). Conclusions: This present meta-analysis suggests that the 8473T>C polymorphism in the COX-2 gene is not a conspicuous low-penetrant risk factor for developing BC.

• The Journal of the Korea Contents Association
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• v.11 no.1
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• pp.1-8
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• 2011

With the development of next IT convergence technology and the construction of infrastructure for personalized services, the importance of services based on user's sensibility status and vital signal is being spotlighted. It is the most crucial factor for the strategy of sensibility engineering to investigate student's vital signal according to the sensibility. In this paper, we proposed the vital signal monitoring simulation system by the various visual stimulus. The proposed method obtained the student's vital signal by the various visual stimulus. And the power spectrum analysis using the fast fourier transform is evaluated the activity level between the sympathetic and the parasympathetic. The analyzed result is monitoring the sensibility by displaying the heath signal light. To evaluate the sensibility between the high school's students and the university's students, we conducted SD profile and paired T-tests so as to verify usefulness. This evaluation found that the difference of sensibility activity by positive and negative stimulus was statistically meaningful. Ultimately, this paper suggests empirical application to verify the adequacy and the validity.

• Nuclear Engineering and Technology
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• v.56 no.3
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• pp.993-1001
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• 2024

The TANDEM project is a European initiative funded under the EURATOM program. The project started on September 2022 and has a duration of 36 months. TANDEM stands for Small Modular ReacTor for a European sAfe aNd Decarbonized Energy Mix. Small Modular Reactors (SMRs) can be hybridized with other energy sources, storage systems and energy conversion applications to provide electricity, heat and hydrogen. Hybrid energy systems have the potential to strongly contribute to the energy decarbonization targeting carbon-neutrality in Europe by 2050. However, the integration of nuclear reactors, particularly SMRs, in hybrid energy systems, is a new R&D topic to be investigated. In this context, the TANDEM project aims to develop assessments and tools to facilitate the safe and efficient integration of SMRs into low-carbon hybrid energy systems. An open-source "TANDEM" model library of hybrid system components will be developed in Modelica language which, by coupling, will extend the capabilities of existing tools implemented in the project. The project proposes to specifically address the safety issues of SMRs related to their integration into hybrid energy systems, involving specific interactions between SMRs and the rest of the hybrid systems; new initiating events may have to be considered in the safety approach. TANDEM will study two hybrid systems covering the main trends of the European energy policy and market evolution at 2035's horizon: a district heating network and power supply in a large urban area, and an energy hub serving energy conversion systems, including hydrogen production; the energy hub is inspired from a harbor-like infrastructure. TANDEM will provide assessments on SMR safety, hybrid system operationality and techno-economics. Societal considerations will also be encased by analyzing European citizen engagement in SMR technology safety.

• The Journal of the Korea Contents Association
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• v.19 no.10
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• pp.511-521
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• 2019

This study is designed to define the smart city as the platform for digital social innovation, and acquire the evaluation indicator for objectively diagnosing domestic cities from the perspective of the implementation process and capability of smart city and analyze its importance. Through prior studies and in-depth interview with experts, candidate groups for evaluation indicators were acquired and the conformance test(T-test) was conducted to finally select 16 detailed indicators in 4 fields. The importance of the evaluation item was found to be high in the policy and system, followed by innovation infrastructure, citizen's participation and infrastructure. The analysis of the 16 detailed indicators for importance showed that the willingness of conducting the smart city by the head of local government, construction of organization dedicated to the smart city have the highest importance. This may reflect the fact that in domestic cities, the smart city is sponsored by public organizations. The analysis of the importance of expert groups (local government and Private sector groups) found that both groups recognized that politics and systems are important factors but they varied in the recognition of importance in the innovation infrastructure and citizen's participation. This study has implication as the indicator for smart city from the perspective of digital social innovation can be acquired for use of the domestic cities and that it can give basic and objective data for the priority of policies on which the domestic smart cities shall focus.