• Title/Summary/Keyword: RssB

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Evidence for VH Gene Replacement in Human Fetal B Cells

  • Lee, Jisoo;Cho, Young Joo;Lipsky, Peter E.
    • IMMUNE NETWORK
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    • v.2 no.2
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    • pp.79-85
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    • 2002
  • Background: In contrast to evidences of Ig H chain receptor editing in transformed cell lines and transgenic mouse models, there has been no direct evidence that this phenomenon occurs in human developing B cells. Methods: $V_HDJ_H$ rearrangements were obtained from genomic DNA of individual $IgM^-$ B cells from liver and $IgM^+B$ cells from bone marrow of 18 wk of gestation human fetus by PCR amplification and direct sequencing. Results: We found three examples of H chain receptor editing from $IgM^+$ and $IgM^-human$ fetal B cells. Two types of $V_H$ replacements were identified. The first involved $V_H$ hybrid formation, in which part of a $V_H$ gene from the initial VDJ rearrangement is replaced by part of an upstream $V_H$ gene at the site of cryptic RSS. The second involved a gene conversion like replacement of CDR2, in which another $V_H$ gene donated a portion of its CDR2 sequence to the initial VDJ rearrangement. Conclusion: These data provide evidence of receptor editing at the H chain loci in developing human B cells, and also the first evidence of a gene conversion event in human Ig genes.

Vertical Handoff Decision System based on Support Vector Machine

  • Oh, Ryong;Yu, Jae-Hak;Kim, Tae-Sub;Lim, Chi-Hun;Ryu, Seung-Wan;Cho, Choong-Ho
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.36 no.7B
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    • pp.771-779
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    • 2011
  • It is expected that many heterogeneous wireless systems, such as 3GPP LTE systems, WiMAX systems and WLAN systems, will coexist in the next generation wireless communication environments. Integrated radio resource management and seamless vertical handoff (VHO) should be supported to provide integrated communication services over multi-radio access networks. A new class of adaptive VHO system that views the handoff problem as a pattern recognition problem is proposed. In this paper, we propose a unified radio resource management (URRM) architecture and Support Vector Machine (SVM) based vertical handoff decision system. Extensive simulation studies show the proposed VHO algorithm outperforms RSS based VHO algorithms in terms of throughput and service cost.

Leg Fracture Recovery Monitoring Simulation using Dual T-type Defective Microstrip Patch Antenna (쌍 T-형 결함 마이크로스트립 패치 안테나를 활용한 다리 골절 회복 모니터링 모의실험)

  • Byung-Mun Kim;Lee-Ho Yun;Sang-Min Lee;Yeon-Taek Park;Jae-Pyo Hong
    • The Journal of the Korea institute of electronic communication sciences
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    • v.18 no.4
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    • pp.587-594
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    • 2023
  • In this paper, we present the design and optimization process of an on-body microstrip patch antenna with a paired T-type defect for monitoring fracture recovery of human legs. This antenna is designed to be light, thin and compact despite the improvement of return loss and bandwidth performance by adjusting the size of the T-type defect. The structure around the applied human leg is structured as a 5-layer dielectric plane, and the complex dielectric constant of each layer is calculated using the 4-pole Cole-Cole model parameters. In a normal case without bone fracture, the return loss of the on-body antenna is -66.71dB at 4.0196GHz, and the return loss difference ΔS11 is 37.95dB when the gallus layer have a length of 10.0mm, width of 1.0mme, and height of 2.0mm. A 3'rd degree polynomial is presented to predict the height of the gallus layer for the change in return loss, and the polynomial has a very high prediction suitability as RSS = 1.4751, R2 = 0.9988246, P-value = 0.0001841.

Three Common Subunits in the Editing Domains of Class Ia tRNA Synthetases.

  • Lee, Keun-Woo;Kwon, Yong-Jung;Briggs, James M.
    • Journal of Industrial Technology
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    • v.24 no.B
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    • pp.139-142
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    • 2004
  • To identify conserved structural or functional subunit(s) in the CP1 (editing) domains of class Ia tRNA synthetases, five available structures were compared and analyzed. Through sequence alignments of the CP1 domains, three conserved regions were found near the amino acid binding site in the editing domain. Structural overlapping of the three subunits clearly showed that there exist three common structural subunits in all of the five editing RS structures. The new alignment suggests a translocation movement of the CP1 domain caused by the binding with tRNA. Based on the experimental and modeling results, it is proposed that subunits 1 and 3 accommodate the incoming amino acid binding, while subunit 2 contributes to the interactions with the adenosine ring of the A76 to stabilize the overall tRNA binding.. Since these subunits are critical for the editing reaction, we expect that these key structures should be conserved through all class Ia editing RSs.

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Survey of Fungicide Resistance for Chemical Control of Botrytis cinerea on Paprika

  • Yoon, Cheol-Soo;Ju, Eun-Hee;Yeoung, Young-Rog;Kim, Byung-Sup
    • The Plant Pathology Journal
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    • v.24 no.4
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    • pp.447-452
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    • 2008
  • Four hundred and sixty six isolates of B. cinerea were obtained from infected leaves, stems and fruits of paprika grown in greenhouses or plastic film houses in Gangwon province, Korea, between August and November in 2006 and 2007. These isolates were classified into five representative phenotypes of resistant (R) and sensitive (S) reactions as SSR, SRR, RSS, RRS and RSR according to the responses of isolates against benzimidazole, dicarboximide and N-phenyl-carbamate fungicide in order. The percentage of five phenotypes were 51.3, 2.4, 35.6, 8.1 and 2.6%, respectively. The SSR phenotype (51.3%) was the most common. Among the nineteen fungicide products evaluated to compare their efficacy against gray mold pathogen on the paprika fruit inoculated with fungal mycelia, the mixture of diethofencarb and carbendazim was the most effective followed by iprodione, boscalid, the mixture of iprodione and thiophanate-methyl, fludioxonil, polyoxin-B, fluazinam, the mixture of tebuconazole and tolyfluanid and procymidone; while in the assay methods inoculated with fungal spores, the mixture of tebuconazole and tolyfluanid was the most effective in controlling gray mold followed by boscalid, fludioxonil, the mixture of diethofencarb and carbendazim and the mixture of pyrimethanil and chlorothalonil.

Positioning Scheme Based on Iterative Path-Loss Exponent Estimation in WSNs (무선 센서 네트워크에서 반복적인 Path-Loss Exponent 추정을 통한 위치추정 기법)

  • Choi, Jun-Ho;Choi, Jae-Kark;Yoo, Sang-Jo
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.37B no.10
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    • pp.889-900
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    • 2012
  • In wireless sensor networks, the positioning scheme using received signal strength (RSS) has been widely considered. Appropriate estimation of path-loss exponent (PLE) between a sensor node and an anchor node plays a key role in reducing position error in this RSS-based positioning scheme. In the conventional researches, a sensor node directly uses the PLEs measured by its nearest anchor node to calculate its position. However, the actual PLE between a sensor node and the anchor node can be different from the PLE measured by its nearest anchor node. Thus, if a sensor node directly uses the PLEs measured by its nearest anchor node, the estimated position is different from the actual position of the sensor node with a high probability. In this paper, we describe the method how a sensor node estimates PLEs from the anchor nodes of interest by itself and calculates its position based on these self-estimated PLEs. Especially, our proposal suggests the mechanism to iteratively calculate the PLEs depending on the estimated distances between a sensor node and anchor nodes. Based on the recalculated PLEs, the sensor node reproduces its position. Through simulations, we show that our proposed positioning scheme outperforms the traditional scheme in terms of position error.

Changes in Sensitivity Levels of Botrytis cinerea Populations to Benzimidazole, Dicarboximide, and N-Phenylcarbamate Fungicides (잿빛곰팡이병균(Botrytis cinerea)의 Benzimidazole계, Dicarboximide계 및 N-phenylcarbamate계 살균제에 대한 감수성 변화)

  • 김병섭;박은우;조광연
    • Korean Journal Plant Pathology
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    • v.14 no.6
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    • pp.693-699
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    • 1998
  • Three three hundred and ninety seven isolates of Botrytis cinerea were isolated from infected plants of strawberry, tomato and cucumber from several areas in Korea during 1994∼1996 and the resistance of these isolates against some fungicides were examined. The isolation frequency of phenotypes resistant to carbendazim, procymidone, and diethofencarb were found to be 69.9 43.7, and 31.8%, respectively. The isolates were divided into six phenotypic groups; SSR, SRR, RSS, RRS, RSR and RRR, representing sensitive (S) or resistant (R) to benzimidazole, dicarboximide, and N-phenylcarbamate fungicides in order. The percentage of six phenotypes were 28.2, 2.0, 27.2, 41.0, 0.9 and 0.8%, respectively. On the basis of the mycelial growth inhibition (%) B. cinerea isolates were divided into three classes (class 1; 0∼50%, class 2; 51-99%, class 3; 100% inhibition) on carbendazim and three classes (class 1; 0∼75%, class 2; 76∼99%, class 3; 100% inhibition) on procymidone and the mixture of carbendazim+diethofencarb, respectively. Changes in sensitivity levles to carbendazim and carbendazim+diethofencarb were affected by introduction and increasing ratio of the use of diethofencarb.

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A Spectrally Efficient Macrodiversity Handover Technique for Interference-Limited IEEE 802.16j Multihop Wireless Relay Networks

  • Sultan, Jamil;Misran, Norbahiah;Ismail, Mahamod;Islam, Mohammad Tariqul
    • ETRI Journal
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    • v.33 no.4
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    • pp.558-568
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    • 2011
  • In this paper, we propose an efficient macrodiversity handover (MDHO) technique for time-division-based interference-limited IEEE 802.16j multihop wireless relay networks. In the proposed MDHO, when the diversity set members of the mobile station (MS) are a base station (BS) and relay station (RS), the MS receives the signal transmitted by the BS in the first phase. During the second phase, it also receives the simultaneous transmissions of the BS and RS. Furthermore, when the diversity set members are two RSs or two BSs, the MS receives only the simultaneous transmissions of the diversity set members. The superiority of the proposed MDHO is validated using analytical and simulation results. The performance analysis metrics are the average downlink (DL) carrier to interference and noise ratio (CINR), the average DL spectral efficiency, and the average service outage probability. Evaluation results show that the proposed MDHO significantly outperforms the conventional MDHO. The CINR gain achieved using the proposed MDHO is 4.71 dB compared to the conventional MDHO.

An Adaptive Coverage Control Algorithm for Throughput Improvement in OFDMA-based Relay Systems (OFDMA 기반 Relay 시스템에서 Throughput 성능 향상을 위한 적응적 커버리지 조절 기법)

  • Hyun, Myung-Reun;Hong, Dae-Hyoung;Lim, Jae-Chan
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.34 no.9B
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    • pp.876-882
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    • 2009
  • In this paper, we propose a sub-cell coverage control algorithm for enhancement of the cell throughput in OFDMA based relay systems. Relay station (RS) is exploited for improved quality of the received signal in cellular communication systems, especially in shadow areas. However, since a RS requires additional radio resource consumption for the link between the base station (BS) and the RS, we have to carefully control the coverage areas if a mobile station (MS) is serviced via the BS or the RS considering the cell throughput. We consider radio resource reuse as well for the sub-cell coverage configuration by applying various reuse patterns between RSs. We also consider a time varying system by adaptively changing the threshold for coverage depending on the MSs' traffic in the cell. We initially determine the sub-cell coverage of the system depending on the ratio of received signal-interference-noise-ratio (SINR) of the MS from the BS and RSs, respectively. Then, the "sub-cell coverage threshold" varies based on the "effective transmitted bits per sub-channel" with time. Simulation result shows that the proposed "time varying coverage control algorithm" leads to throughput improvement compared to the fixed sub-cell coverage configuration.

Performance Analysis of Single-frame Mode and Multi-Frame Mode in IEEE802.16j MMR System (IEEE802.16j MMR 시스템에서 Single-Frame 방식과 Multi-Frame 방식의 성능 분석)

  • Kim, Seung-Yeon;Kim, Se-Jin;Yoo, Chang-Jin;Ryu, Seung-Wan;Lee, Hyong-Woo;Cho, Choong-Ho
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.33 no.6B
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    • pp.403-410
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    • 2008
  • In this paper, we investigate the performance of MMR system in Non-transparent mode. The IEEE 802.16j MMR system has two node of operation, Single-frame (in band) and Multi-frame (out band) mode. In the analysis, we assume that channel interference between MR-BS and RS, or between RSs anywhere in the given area is ignored. The performance is presented in terms of the delay and the frame efficiency by varying number of RS and BS coverage to RS coverage ratio and the maximum coverage area of a BS by varying traffic density. Analytical results show that the Single-frame is more efficient than Multi-frame in frame efficiency and coverage extension.