• Title/Summary/Keyword: Rps

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Red pepper seed water extract inhibits preadipocyte differentiation and induces mature adipocyte apoptosis in 3T3-L1 cells

  • Kim, Hwa-Jin;You, Mi-Kyoung;Lee, Young-Hyun;Kim, Hyun-Jung;Adhikari, Deepak;Kim, Hyeon-A
    • Nutrition Research and Practice
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    • v.12 no.6
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    • pp.494-502
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    • 2018
  • BACKGROUND/OBJECTIVES: Reducing the number of adipocytes by inducing apoptosis of mature adipocytes as well as suppressing differentiation of preadipocytes plays an important role in preventing obesity. This study examines the anti-adipogenic and pro-apoptotic effect of red pepper seed water extract (RPS) prepared at $4^{\circ}C$ (RPS4) in 3T3-L1 cells. MATERIALS/METHODS: Effect of RPS4 or its fractions on lipid accumulation was determined in 3T3-L1 cells using oil red O (ORO) staining. The expressions of AMP-activated protein kinase (AMPK) and adipogenic associated proteins [peroxisome proliferator-activated receptor-${\gamma}$ ($PPAR-{\gamma}$), CCAAT/enhancer-binding proteins ${\alpha}$ (C/EBP ${\alpha}$), sterol regulatory element binding protein-1c (SREBP-1c), fatty acid synthase (FAS), and acetyl-CoA carboxylase (ACC)] were measured in 3T3-L1 cells treated with RPS4. Apoptosis and the expression of Akt and Bcl-2 family proteins [B-cell lymphoma 2 (Bcl-2), Bcl-2-associated death promoter (Bad), Bcl-2 like protein 4 (Bax), Bal-2 homologous antagonist/killer (Bak)] were measured in mature 3T3-L1 cells treated with RPS4. RESULTS: Treatment of RPS4 ($0-75{\mu}g/mL$) or its fractions ($0-50{\mu}g/mL$) for 24 h did not have an apparent cytotoxicity on pre and mature 3T3-L1 cells. RPS4 significantly suppressed differentiation and cellular lipid accumulation by increasing the phosphorylation of AMPK and reducing the expression of $PPAR-{\gamma}$, C/EBP ${\alpha}$, SREBP-1c, FAS, and ACC. In addition, all fractions except ethyl acetate fraction significantly suppressed cellular lipid accumulation. RPS4 induced the apoptosis of mature adipocytes by hypophosphorylating Akt, increasing the expression of the pro-apoptotic proteins, Bak, Bax, and Bad, and reducing the expression of the anti-apoptotic proteins, Bcl-2 and p-Bad. CONCLUSIONS: These finding suggest that RPS4 can reduce the numbers as well as the size of adipocytes and might useful for preventing and treating obesity.

Analysis for Annualized Returns of Island Microgrid IPP According to CER Price (CER 가격에 따른 도서지역용 MG 발전사업자의 연평균수익률 분석)

  • Kim, Mi-Young
    • The Transactions of The Korean Institute of Electrical Engineers
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    • v.67 no.4
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    • pp.512-521
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    • 2018
  • Islands that is far away from onshore have used internal-combustion engine driving alternators to secure electric power. However, with Paris convention on climate change, there is a growing interest in eco-friendly energy independent island that replaces microgrid(MG) consisting of photovoltaic, wind power, and energy storage system with alternators for internal combustion engines. And also, national emission trading has been implemented, and the price of certified emission reduction(CER) has a influence on system marginal price(SMP). Because, the low cost generation source decides SMP when CER price is low, while the more expensive generation source decides SMP when CER price is high. Therefore, the increasing of CER price has a strong influence on the annualized return of MG independent power producer. Moreover, the fixed RPS price is implemented from 2017, which the increasing of CER price under the fixed RPS price or the variable RPS price affects annualized return differently. In this paper, the annualized return according to CER price is analyzed for large, middle, and small scaled islands, the effect of CER price on the annualized return was confirmed.

2-Dimensional Numerical Analysis of Crossing Tunnel under Railroad using Roof Panel Shield Method (RPS공법을 이용한 철도횡단터널의 2차원수치해석)

  • Shin, Eun-Chul;Roh, Jeong-Min;Lee, Eun-Soo;Kim, Kyeong-Mo;Kim, Jung-Hyi;Jung, Byung-Chul
    • Proceedings of the Korean Geotechical Society Conference
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    • 2005.10a
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    • pp.591-600
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    • 2005
  • There are many cross tunnelling methods such as NTR, TRCM, Messer Shield, Front Jacking, and Pipe Roof Method. The advantages of adopting RPS(roof panel shield) method in crossing tunnel construction with comparing other existing cross tunnelling method are needed a little space and easy to change the direction of cutting shoe during the construction of pipe roof. The numerical analysis of RPS was performed for the application in the crossing tunnel under railroad. The earth pressure distribution and settlement were predicted when the RPS method was applied during the excavation for crossing railroad tunnel construction.

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A Study on the Method about the Economic Feasibility Estimation Considering Renewable Energy (신재생에너지원을 고려한 집단에너지 경제성평가 방법론에 관한 연구)

  • Shin, Hye-Kyeong;Choi, Young-Jun;Choi, In-Sun
    • 한국신재생에너지학회:학술대회논문집
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    • 2008.10a
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    • pp.372-374
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    • 2008
  • Korea classified into a development country when UNFCCC was concluded in 1995. So Korea doesn't have a GHG reduction duty until 2012. As the UNFCCC is strengthened, recently there is a growing interest in renewable energy and energy usage efficiency improvement for reducing GHG emission. It is associated with CES and renewable energy. CES is a total energy (heat, cooling and power)supplier in aggregated demand zone like a hotel, building, hospital and redevelopment district using CHP and it improves energy usage efficiency. At present, renewable energy is needed for GHG reduction duty but renewable energy doesn't have economic feasibility. So renewable energy is needed various support system to popularize which is a FIT and RPS. Especially RPS is carrying out instead of FIT in many advanced country and it will be inroduced in Korea. RPS is a duty which electricity service provider must guarantee renewable energy as much as specific ratio of total capacity. Therefore this study conducts an economic feasibility estimation of CES considering renewable energy when RPS will introduced in the future.

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A Study on the Present State of Duty Performance According to the RPS System and Improvement Plan (RPS제도 시행에 따른 의무이행 현황 분석 및 개선방안 연구)

  • Kim, Jun-Hui;Lee, Eung-Jik
    • Journal of the Korean Solar Energy Society
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    • v.33 no.6
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    • pp.98-104
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    • 2013
  • At the moment, in Korea, over 90% of energy resources depend on imports, and nearly 60% of electric energy is produced using fossil fuel. Therefore, the government adopted the Climatic Change Convention and has implemented the RPS system since 2012 to actively cope with the dependence on imported energy, and to grow and expand the new renewable energy industry. This study examined the performance results of mandatory supply of solar photovoltaic energy and non-solar photovoltaic energy assigned to providers and the present state after implementation of the RPS system. As a result, the achievement rate in 2012 was 64.7%. Especially, solar photovoltaic energy showed a high achievement rate of 95.7%, whereas non-solar photovoltaic energy showed a low achievement rate of 63.3% due to several problems and was highly dependent on the government. In 2013, the burden of each provider has increased due to more mandatory supply and addition of unfulfilled supply of 2012, and the separate mandatory supply of solar photovoltaic energy established for protection of the solar photovoltaic market is restricting investment. Therefore, there is a need to assign mandatory supply in consideration of the available amount of each new renewable energy.

Assessment of Microorganism-derived Adjuvants for Scuticociliate Miamiensis avidus Vaccine (스쿠티카충Miamiensis avidus 주사백신용 미생물유래 면역보조제의 평가)

  • Jung, Myung-Hwa;Jung, Sung-Ju
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.54 no.5
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    • pp.652-659
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    • 2021
  • Microorganism-derived compounds, such as peptidoglycan, lipoteichoic acid, and β-glucan were supplemented in the scuticociliate Miamiensis avidus (M. avidus) vaccine to verify the specify component contribution to the adjuvant effect. Vaccine was formulated with the inactivated M. avidus antigen (YS2, 4.44×105 cells/fish) in combination with either peptidoglycan (10 ㎍ and 100 ㎍/fish), lipoteichoic acid (5 ㎍ and 50 ㎍/fish), or β-glucan (10 ㎍ and 100 ㎍/fish). Olive flounder injected with peptidoglycan supplemented vaccine (10 ㎍ and 100 ㎍/fish) exhibited significant protection, and the relative percent survival (RPS) was 55% and 65% at 4 weeks post vaccination (wpv), respectively, at the corresponding doses. The vaccine groups with added lipoteichoic acid (5 ㎍ and 50 ㎍/fish) exhibited RPS of 40% and 5%, respectively. Additionally, the group with added β-glucan (100 ㎍/fish) exhibited RPS of 35%, but no effect was observed in the group with added 10 ㎍/fish β-glucan. At 8 wpv, olive flounder injected with peptidoglycan and lipoteichoic acid supplemented vaccines exhibited protection with RPS range of 11/11% and 5/21%, respectively, at the respective doses. M. avidus vaccine containing 10 ㎍ and 100 ㎍/fish of β-glucan exhibited the RPS of 32% and 37%, respectively. Conclusively, peptidoglycan contributed in high protection of the M. avidus vaccine, and thus, it can be used as an effective adjuvant in the M. avidus vaccine.

Mapping the Star Formation Activity of Five Jellyfish Galaxies in Massive Galaxy Clusters with GMOS/IFU

  • Lee, Jeong Hwan;Lee, Myung Gyoon;Mun, Jae Yeon
    • The Bulletin of The Korean Astronomical Society
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    • v.46 no.2
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    • pp.43.2-43.2
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    • 2021
  • Ram-pressure stripping (RPS) is known as the main driver of quenching the star formation (SF) activity in cluster galaxies. However, galaxies undergoing RPS in galaxy clusters often show blue star-forming knots in their disturbed disks and tails. The existence of these "jellyfish galaxies" implies that RPS can temporarily boost the SF activity of cluster galaxies. Thus, jellyfish galaxies are very unique and interesting targets to study the influence of RPS on their SF activity, in particular with integral field spectroscopy (IFS). While there have been many IFS studies of jellyfish galaxies in low-mass clusters (e.g., the GASP survey), IFS studies of those in massive clusters have been lacking. We present an IFS study of five jellyfish galaxies in massive clusters at intermediate redshifts using the Gemini GMOS/IFU. Their star formation rates (SFRs) are estimated to be up to 15 Mo/yr in the tails and 50 Mo/yr in the disks. These SFRs are by a factor of 10 higher than those of star-forming galaxies on the main sequence in the M*-SFR relation at similar redshifts. Our results suggest that the SF activity of jellyfish galaxies tends to be more enhanced in massive clusters than in low-mass clusters. This implies that strong RPS in massive clusters can trigger strong starbursts.

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Problem Solving of Kitchen Knife using RPS-TRIZ (RPS-TRIZ를 활용한 식칼의 문제해결)

  • Leem, Sa-Hwan;Huh, Yong-Jeong;Lim, Ju-Yeon
    • Proceedings of the KAIS Fall Conference
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    • 2011.05b
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    • pp.638-640
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    • 2011
  • 주방 등에서 사용하는 식칼은 음식물을 절단하는 경우 음식물이 식칼에 달라붙어 잘 떨어지지 않는 문제를 가지고 있다. 이로 인하여 식칼과 음식물이 쉽게 분리되지 않아 조리작업 및 조리시간이 많이 소요된다. 따라서 조리작업 및 조리시간을 단축하기 위하여 식칼에 음식물이 붙지 않아야 한다. 본 논문은 주방에서 사용하는 식칼의 문제점을 RPS-TRIZ를 활용하여 해결하였다.

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A Study on the Change in Production Costs and Electricity Tariffs with the Introduction of Renewable Portfolio Standard (RPS(Renewable Portfolio Standard) 제도 도입을 고려한 전기요금변화에 관한 연구)

  • Hong, Hee-Jung;Han, Soek-Man;Kim, Bal-Ho
    • The Transactions of The Korean Institute of Electrical Engineers
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    • v.58 no.4
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    • pp.708-717
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    • 2009
  • Recently, Korea government decided to introduce RPS (Renewable Portfolio Standard) mechanism which requires electricity providers to gradually increase the amount of renewable energy sources such as wind, solar, bioenergy, and geothermal. As a consequence, it is expected that the long-term fuel mix would be changed to result in more expensive production and the increased production costs would be distributed to the rate payers via electricity tariffs. This paper presents the change in long-term fuel mix in year 2020 with the four RPS scenarios of 3%, 5%, 10% and 20%, and the methodologies for collecting the increased production costs through new tariff schedule. The studies on long-term fuel mix have been carried out with the GATE-PRO (Generation And Transmission Expansion Program) optimization package, a mixed-integer program developed by the Korea Energy Economics Institute and Hongik university. Three methodologies for distributing the production costs to the rate payers have also been demonstrated.