• Journal of Animal Reproduction and Biotechnology
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• v.36 no.2
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• pp.116-120
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• 2021

Three different cats who had chronic kidney disease (CKD) were treated for more than one month with fluid therapy in an animal clinic. Although this long-term treatment and hospitalization, there was no clinical improvement in clinical signs as well as serum biochemical indexes including blood urea nitrogen (BUN), creatinine (CREA), and phosphate (PHOS). All cases were then injected three times with allogeneic stem cells through an intravenous route for treatment on Day 0, 7, and 14 or 30. On the same day, clinical observation and blood tests for serum biochemistry were conducted together. Upon administrating stem cells to the CKD cats, clinical conditions and the indexes of BUN and CREA were clinically improved within normal ranges. Additionally, one of the cats who had the renal cysts presented clinical improvement with showing decreased cysts size than before.

• Proceedings of the Korea Information Processing Society Conference
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• 2013.11a
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• pp.400-401
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• 2013

Mobility in a network causes link disconnections and link recovery is vital for reliability of a network. A link failure affects all the preceding nodes on a damaged routing path; creates communication delay, throughput degradation, and congestion. This paper proposes link recovery mechanisms in CCN based networks. Packet overhearing is used to update neighboring nodes information. The recovery is done by forwarding node resulting in low control overhead, and better efficiency. The proposed mechanisms increase overall performance of a typical CCN and simulation results show that our proposed scheme works very well in densely populated networks with high mobility.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.18 no.5
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• pp.1215-1223
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• 2014

In multi-hop wireless networks, a message transmission path is set up on demand by a route discovery step, where a shortest path is used in general. The shortest path, however, normally uses the nodes near the center area, which causes a high traffic load in that area and reduces the message transmission reliability. We propose a stable routing protocol considering the remaining energy of nodes. Our protocol uses ETX as a link performance estimator and tries to avoid the nodes with smaller energy. By doing this, we can reduce the route failure probability and packet loss. We have evaluated the performance of the proposed protocol using QualNet and compared with AODV and MRFR protocols. The simulation result shows that our protocol has a similar performance as MRFR in terms of end-to-end message reception ratio, average message delay and delay jitter, but outperforms MRFR in terms of traffic load distribution.

• Journal of KIISE:Computer Systems and Theory
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• v.33 no.9
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• pp.677-683
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• 2006

If a node stops functioning in an ad-hoc wireless network, routing paths involving the node will also fail, when construction of replacement routes is required. A major cause of node failure is energy exhaustion, and route replacements may in turn lead to successive node failures by making more nodes consume their energy. The result could be performance degradation of networks. Therefore it is important to ensure that nodes with limited remaining energy are not included in route construction from the beginning. In this paper we propose a new routing protocol, which takes residue energy of nodes into account in order to prevent node failures resulting from energy shortage. Our routing protocol examines the smallest value of node residue energy ($E_{m}$) from each of all possible routing paths and selects the path which has the largest value of $E_{m}$. We prove, through simulation, that our routing protocol extends the lifetime of nodes which have limited amount of energy, reducing chances of path replacement. It is also shown that our proposed protocol helps alleviate network performance degradation.

• The Microorganisms and Industry
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• v.25 no.1
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• pp.2-9
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• 1999

A study was made on enzymes of carbohydrate metabolism in T. concretivorus grown with and without glucose. The present results show that T. concretivorus possesses high activities of pentose shunt pathway and related enzymes, glucokinase, G-6-P dehydrogenase, 6-PG dehydrogenase, and phosphoglucoisomerase, but low activities of enzymes unique to EMP(fructose-1,6-diphosphate aldolase). Although the synthesis of the latter enzymes remains largely unaffected by the growth enviroment, that of the former is stimulated by glucose. And the failure to detect ED pathway enzymes in cells grown in thiosulate or thiosulfate-glucose medium eliminates the ED pathway as a significant route of glucose catabolism in T.concretivorus. These results suggest that pentose shunt pathway performs an energetic role in glucose metabolism by T.concretivorus with EMP as a subway. The absence of ED pathway and the presence of pentose shunt pathway which is the major route of catabolism in T.concretivorus are similar to those of other obligately chemolitho-trophic thiobacilli. The G-6-P and 6-PG dehydrogenase are both NAD and NADP specific, but MAD predominant. However, the 3-PGAL dehydrogenase is only NAD specific. Since the specific activity of 3-PGAL generated from glucose is converted mainly into pyruvate which is channeled into the TCA cycle. All enzymes of the TCA cycle tested and NADH oxidase are detected in the cells of T.concretivorus grown in thiosulfate. The specific activities of fumarase and isocitrate dehydrogenase are high and others are low. The presence of two isocitrate dehydrogenase (NAD-and NADP-linked) may have important regulatory function for this organism. The activity of NAD-oxidase, which is implicated in the energy generating metabolism, was very high in the crude cell-free extract of T.concretivorus, recording 55.11 m.mu. mole/min/mg protein. This well coincides with the fact that activities of NAD-linked G-6-P dehydrogenase, 6-PG dehydrogenase and 3-PGAL dehydrogenase were high.

• Korean Journal of Microbiology
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• v.11 no.1
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• pp.1-18
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• 1973

A study was made on enzymes of carbohydrate metabolism in T. concretivorus grown with and without glucose. The present results show that T. concretivorus possesses high activities of pentose shunt pathway and related enzymes, glucokinase, G-6-P dehydrogenase, 6-PG dehydrogenase, and phosphoglucoisomerase, but low activities of enzymes unique to EMP(fructose-1, 6-diphosphate aldolase). Although the synthesis of the latter enzymes remains largely unaffected by the growth enviroment, that of the former is stimulated by glucose. And the failure to detect ED pathway enzymes in cells grown in thiosulate or thiosulfate-glucose medium eliminates the ED pathway as a significant route of glucose catabolism in T.concretivorus. These results suggest that pentose shunt pathway performs an energetic role in glucose metabolism by T.concretivorus with EMP as a subway. The absence of ED pathway and the presence of pentose shunt pathway which is the major route of catabolism in T.concretivorus are similar to those of other obligately chemolitho-trophic thiobacilli. The G-6-P and 6-PG dehydrogenase are both NAD and NADP specific, but MAD predominant. However, the 3-PGAL dehydrogenase is only NAD specific. Since the specific activity of 3-PGAL generated from glucose is converted mainly into pyruvate which is channeled into the TCA cycle. All enzymes of the TCA cycle tested and NADH oxidase are detected in the cells of T.concretivorus grown in thiosulfate. The specific activities of fumarase and isocitrate dehydrogenase are high and others are low. The presence of two isocitrate dehydrogenase (NAD-and NADP-linked) may have important regulatory function for this organism. The activity of NAD-oxidase, which is implicated in the energy generating metabolism, was very high in the crude cell-free extract of T.concretivorus, recording 55.11 m$\mu$ mole/min/mg protein. This well coincides with the fact that activities of NAD-linked G-6-P dehydrogenase, 6-PG dehydrogenase and 3-PGAL dehydrogenase were high.

• Journal of the Korean Society of Marine Environment & Safety
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• v.22 no.5
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• pp.389-401
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• 2016

This study attempted to present the monthly distribution of the inshore gill netters for the prevention of propeller failure caused by the damage of fishing gear by the merchant vessels in the West Sea. This study was conducted using the transmitting device of fishing location (V-Pass) data for 1 year in 2014. The grid intervals are $30minute{\times}30minute$ ($latitude{\times}longitude$) based on the section of the sea. A total of 56 sections were analyzed by constructing a grid. The results revealed that the section no. 194 with the highest density index showed no fishing gear damage accident. But the section no. 193 with a relatively lower density index showed more frequent fishing gear damage accident. It is because the section no. 193 is included in the main route of the merchant vessels. Based on this analysis, it is found that the fishing gears are not damaged in proportion to density index but risk of damage exists according to the main routes of merchant vessels. Therefore, for the safe navigation of the merchant vessels, notifying the waters of $34.5^{\circ}{\sim}35.5^{\circ}$ at latitude and $125.67^{\circ}{\sim}126^{\circ}$ at longitude, as a navigational warning area from May through September, will prevent marine accident, such as propeller failure and fishing gear damage. Accordingly, when the merchant vessels navigate in the section no. 193 and 203, the area of $34.5^{\circ}{\sim}35.5^{\circ}$ at latitude and $125.5^{\circ}{\sim}125.67^{\circ}$ at longitude is recommended for the safe navigation.

• Journal of Veterinary Clinics
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• v.23 no.3
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• pp.320-324
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• 2006

The purpose of the present study was to compare pulsatile type(Twin Pulse Life Support; TPLS) with rotary type hemodialyzer(AK95) in order to reduce the dialysis time and to improve dialysis effect. Three healthy dogs(about 30 kg BW) were used. Experimental renal failure was induced by the ligation of bilateral renal artery. A pair of catheters were implanted in jugular vein for dialysis. Daily investigated parameters included clinical signs such as vomiting, fecal appearance and activity, and also laboratory data such as PCV, TP, BUN and creatinine. Hemodialysis was started above 90 mg/100 ml BUN level and, laboratory data were measured every an hour for 4 hours. Heparin was administered 300 IU/Kg before dialysis and 150 IU/Kg via IV route every 90 minutes during dialysis. Clinical signs after induction renal failure were shown severe vomiting, anorexia, diarrhea, mucous feces, ataxia, dilated pupil and episcleral hyperemia. The average of BUN value decreased hourly $99{\pm}12.1,\;84{\pm}12.2,\;72{\pm}8.0,\;58{\pm}7.1,\;48{\pm}5.2,\;and\;39{\pm}3.2mg/100ml$ by hemodialysis. The average of creatinine value decreased $7.8{\pm}0.61,\;6.4{\pm}0.40,\;5.3{\pm}0.42,\;4.5{\pm}0.23,\;4.0{\pm}0.41,\;and\;3.4{\pm}0.42mg/100ml$ according to hemodialysis an hour. There are not significantly differences BUN, creatinine, PCV and TP values between pulsatile and rotary type hemodialysis. These results suggested that effects of hemodialysis with Pulsatile type(TPLS) are not significantly difference as compared with hemodialysis of rotary type(AK95). Further research is needed in order to estimate the influence of cardiovascular and pulmonary system in hemodialysis of pulsatile type.

• Journal of the Korean Data and Information Science Society
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• v.22 no.3
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• pp.389-400
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• 2011

This study was carried out to analysis factors related to in-hospital mortality of community-acquired peumonia using administrative database. The subjects were 5,353 community-acquired pneumonia inpatients of the Korean National Hospital Discharge Injury Survey 2004-2006 data. The data were analyzed using chi-squared test and decision tree model in the data mining technique. Among the decision tree model, C4.5 had the best performance. The critical factors on in-hospital mortality of communityacquired pneumonia are admission route, respiratory failure, congenital heart failure including age, comorbidity, and bed size. This study was carried out using the administrative database including patients' characteristics and comorbidity. However further study should be extensively including hospital characteristics, regional medical resources, and patient management practice behavior.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.16 no.7
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• pp.1541-1548
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• 2012

This paper proposes a new multipath-based routing protocol on MANETs with Fast-Recovery of failures. The proposed protocol establishes the primary and secondary paths between a source and a destination considering the end-to-end packet reception reliability of routes. The primary path is used to transmit messages, and the secondary path is used to recover the path when detecting failures on the primary path. If a node detects a link failure during message transmission, it can recover the path locally by switching from the primary to the secondary path. By allowing the intermediate nodes to recover locally the route failure, the proposed protocol can reduce the number of packet loss and the amount of control packets for setting up new paths. The simulation result using QualNet simulator shows that the proposed protocol was about 10-20% higher than other protocols in terms of end-to-end message delivery ratio and the fault recovery time in case of link fault was about 3 times faster than the other protocols.