• Restorative Dentistry and Endodontics
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• v.28 no.4
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• pp.295-302
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• 2003

본 연구에서는 인산 칼슘 근관 봉함재 [Apatite Root Sealer (ARS) Type I, II, III]의 세포독성을 혼합후의 시간 경과에 따라서 다른 4계열의 근관 봉함재 (Pulp Canal Sealer EWT, AH Plus, Sealapex, Ketac Endo)와 비교하여 평가하였다. 근관 봉함재를 혼합한 후 1시간, 8시간, 24시간, 48시간, 1주, 2주,4주의 기간동안 배양액을 이용하여 추출액을 얻었다. L929 쥐섬유아세포를 24시간동안 각 시간군에서 얻은 추출액과 함께 배양한 후 dimethylthiazol diphenyltetrazolium (MTT) assay와 neutral red (NR) assay를 이용하여 세포독성(%)을 평가하였다. 실험 결과 ARS Type I, II, III는 전 시간군에 걸쳐 낮은 세포독성을 보였고 (23.65-0.55%) 특히 경화 초기에 다른 계열의 근관 봉함재보다 유의성 있게 낮은 세포독성을 나타내었다. ARS Type I, II, III간의 세포독성은 각 시간군에서 유의성 있는 차이를 보이지 않았다. AH Plus와 Ketac Endo는 초기에 높은 세포독성을 보였으나 AH Plus는 8시간 이후에, Ketac Endo는 24시간 이후에 독성이 급격히 감소하여 ARS와 유의성 있는 차이를 보이지 않았다. Pulp Canal Sealer EWT와 Sealapex는 4주까지 지속적인 세포독성을 나타내었다. 그리고 MTT assay와 NR assay를 이용하여 얻은 각 근관봉함재의 세포독성은 시간 경과에 따라서 비슷한 변화 양상을 나타내었다. 인산 칼슘 근관 봉함재는 생체적합성이 우수한 재료로써 앞으로 지속적인 개발과 평가가 필요할 것으로 사료된다.

• Restorative Dentistry and Endodontics
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• v.41 no.3
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• pp.189-195
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• 2016

Objectives: A variety of root canal sealers were recently launched to the market. This study evaluated physicochemical properties, biocompatibility, and sealing ability of a newly launched resin-based sealer (Dia-Proseal, Diadent) compared to the existing root canal sealers (AHplus, Dentsply DeTrey and ADseal, Metabiomed). Materials and Methods: The physicochemical properties of the tested sealers including pH, solubility, dimensional change, and radiopacity were evaluated. Biocompatibility was measured using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay. For microleakage test, single-rooted teeth were instrumented, and obturated with gutta-percha and one of the sealers (n = 10). After immersion in 1% methylene blue solution for 2 weeks, the specimens were split longitudinally. Then, the maximum length of staining was measured. Statistical analysis was performed by one-way analysis of variance followed by Tukey test (p = 0.05). Results: Dia-Proseal showed the highest pH value among the tested sealers (p < 0.05). ADseal showed higher dimensional change compared to AHplus and Dia-Proseal (p < 0.05). The solubility values of AHplus and Dia-Proseal were similar, whereas ADseal had the lowest solubility value (p < 0.05). The flow values of sealer in increasing order were AHplus, DiaProseal, and ADseal (p < 0.05). The radiopacity of AHplus was higher than those of ADseal and Dia-Proseal (p < 0.05). The cell viability of the tested materials was statistically similar throughout the experimental period. There were no significant differences in microleakage values among the tested samples. Conclusions: The present study indicates that Dia-Proseal has acceptable physicochemical properties, biocompatibility, and sealing ability.

• Restorative Dentistry and Endodontics
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• v.12 no.2
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• pp.65-72
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• 1987

The purpose of this study was to examine the influence of several root canal sealers on the discoloration of internal surface after root canal obstruction. Twenty four sound human premolars, extracted for orthodontic or prosthodontic purposes, were randomly selected and divided into eight groups. Extracted premolars were prepared, and the following seven materials were introduced into the pulp cavities: AH 26, Fuji ionomer (Type I) cement, N2, Oxypara "Murakami", Kerr sealer, PCA sealer, and G-C's Propac ZOE cement. After 7 weeks of incubation; the discolored tooth crowns were hemisectioned, and the internal staining patterns were examined. Then, with an association of observed values the mean intensity scores and percentage of coverage scores of the internal staining patterns in teeth attained by two observers using for Chisquare test were analyzed. The results were as follows: 1. All the experimental premolar's crown showed various ranged discoloration of internal surface. 2. There was no significance between the association scores of two observers participated into this experiments:% coverage scores (P > 0.05) and intensity (P > 0.05) 3. The crowns filled with PCA sealer, AH 26, and Fuji ionomer cement was visible within a depth of one third of dentin. (P> 0.05) 4. For N2, Kerr sealer, and G-C's Propac cement, A slight dentinal staining was recorded, which penetrated up to half way into the dentin. (P> 0.05) 5. It was noticed that the teeth filled with Oxypara "Murakami" were discolored more than two thirds of the dentinal layer. 6. On the control group, there was no discoloration.

• Restorative Dentistry and Endodontics
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• v.24 no.2
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• pp.356-363
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• 1999

The purpose of this study was to compare the apical sealing effect of Microseal obturation technique with lateral condensation technique in 26 recently extracted single rooted teeth. The root canals were instrumented using step-back technique and obturated with laterally condensed gutta-percha or Microseal. Teeth were suspended in methylene blue dye for 2 days and then longitudinary splited. The apical microleakage and the adaptability of gutta-percha to the root canal wall were examined under a stereomicroscope at ${\times}20$ magnification. The results were as follows: 1. The mean leakage was 1.38${\pm}$1.18 mm for laterally condensed gutta-percha group, and 0.71${\pm}$0.57 mm for Microseal gutta-percha group. But there was no statistical difference between two groups. 2. In Microseal gutta-percha group, they showed no gap between the master cone and Microseal gutta-percha, and showed homogeneous mass. 3. In contrast, laterally condensed gutta-percha group showed some gaps not only between gutta-percha cones, but also between gutta-percha cones and the canal walls, and the gaps were filled with some sealer. And also this group showed some amout of sealer on the root canal walls, Within the limits of the results of this experiment, Microseal gutta-percha obturation technique demonstrated relatively favorable apical sealing effect and shorter obturation time. Thus, it is thought that this obturation technique is a acceptable method for clinical use but further studies on this matter should be conducted.

• Proceedings of the KACD Conference
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• 2002.11a
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• pp.697-697
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• 2002

No Abstract, See Full Text

• Restorative Dentistry and Endodontics
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• v.17 no.2
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• pp.365-382
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• 1992

The purpose of this study was to evaluate the adaptation of filling material to the dentinal walls of root canals with and without smear layer. Fifty extracted upper and lower anterior teeth were selected, and the root canals were instrumented with K - files 1mm short of the apical foramen by step - back method. The teeth were randomly divided into two groups of 25 each : in the group I, smear layers were not removed, and in the group II, smear layers were removed by 15% EDTA solution. Again the two groups 25 teeth were randomly divided into unfilled contol group and filling groups(lateral, ultrasonic, ULTRAFIL, McSpadden compaction group). Upon completion of root canal filling, the teeth were grooved on the both the labial and lingual surfaces and then split with mallet and chisel. Each specimens were examined with JSM - 840 Scanning Electron Microscope (JEOL., Japan). The results were as follows : 1. In the contol group, dentinal tubules of group I couldn't be distinguished in the canal wall, but those of group II appeared to be open and patent. 2. In the filling groups of group I, the tubular penetration of the sealer or gutta percha couldn't be seen, but in the filling groups of group II, it could be seen except McSpadden compaction group. 3. In the filling groups, ULTRAFIL group showed the best adaptation of filling material to root canal wall among the group I, and lateral and ultrasonic condensation group showed the best adaptation of filling material among the group II. McSpadden compaction group showed the worst adaptation in group I, II. 4. Generally, the group II showed better adapation of filling material to root canal wall than the group I.

• Journal of Korean Dental Science
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• v.14 no.2
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• pp.61-68
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• 2021

Purpose: The aim of this study was to investigate the outcomes of endodontic treatment of mandibular second molar with C-shaped canal in elderly patients and related factors affecting the survival of the tooth. Materials and Methods: From 2010 to 2015, the survival rate following endodontic treatment was evaluated in elderly patients over 60 years who visited the Veterans Health Service Medical Center for endodontic treatment. The presence of C-shaped canals was confirmed using clinical records and radiographic features. Patient's age, sex, systemic diseases, tooth location, vitality, signs and symptoms, fractures, caries, apical radiolucency, canal shaping methods, sealer leakage, filling voids, and restoration of prosthesis were included in the analyses as confounding variables. The survival rate of teeth was analyzed using Kaplan-Meire analysis and the relationship between the survival rate and variables was analyzed using Simple and Multiple Cox regression analysis. Result: In total, 107 teeth in elderly patients had C-shaped canal. The survival rate of teeth that received endodontic treatment was 63.70%. None of the factors investigated significantly influenced the survival rate (P>0.05). Conclusion: In elderly patients with C-shaped canal, the survival rate after root canal treatment was not significantly different from that of other mandibular molars.

• Restorative Dentistry and Endodontics
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• v.48 no.1
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• pp.5.1-5.22
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• 2023

This systematic review and network meta-analysis aimed to answer the following focused research question: "Does the type of endodontic sealer affect the postoperative pain in patients who received endodontic treatment?" Different databases and grey literature were surveyed. Only one randomized controlled trial were included. The risk of bias in the studies was evaluated by using the Cochrane Collaboration's tool. A random-effects meta-analysis was conducted to compare the risk and intensity of postoperative pain. The quality of the body of evidence was assessed using the Grading of Recommendations Assessment, Development, and Evaluation approach. Out of 11,601 studies, 15 remained for qualitative analyses and 12 for meta-analysis. Seven studies were classified at high risk of bias, and 8 studies raised some concerns. No significant differences between the endodontic materials were observed in the direct comparisons, both in risk and in intensity of postoperative pain (pairwise comparisons with 2 studies: I² = 0%; p > 0.05 and 8 studies: I² = 23%; p > 0.05, respectively). The certainty of the evidence was graded as low or moderate. There was no difference in the risk and intensity of postoperative pain after filling with different endodontic sealers. Further systematic reviews should be conducted.

• Restorative Dentistry and Endodontics
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• v.28 no.1
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• pp.89-99
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• 2003

The purpose of this study was to investigate the bonding of resin- based root canal sealer, AH26 when the sealer was applied as a thin layer between dentine and gutta-percha surface. In this study forty non-caries extracted human molars and resin-based root canal sealer(AH 26, DeTrey/Dentsply, Germany) were used. Disks of gutta-percha, 6mm in diameter.6mm thick (Diadent/Dentsply, Korea) for thermoplastic obturation were used and dentin surfaces were treated with 2% NaOCl(Group 1) or 2%NaOCl+17% EDTA(Group 3). Disks of gutta-Percha, 6mm in diameter.6mm thick (Diadent/Dentsply, Korea) for conventional obturation were used and dentin surface were treated with 2% NaOCl(Group 2) or 2%NaOCl+17% EDTA(Group 4). Enamel was removed by a horizontal section 1mm below the deepest portion of the central occlusal groove by using a watercooled low speed diamond saw. A second horizontal section was done around cementoenamel junction. Exposed dentin surface was cut to approximately $8{\times}8{\;}mm$ rectangular shape and was ground against 320, 400, 600 grade silicon carbide abrasive paper serially. After grinding, the dentine surface were soaked in a solution of 2% NaOCl for 30 minutes and twenty of specimens were treated with 17% EDTA solution for 1 minute. The treated specimens were washed and dried, Root canal sealer, AH26 was prepared according to the manufacture's instructions The Gutta-percha and dentin surface were coated with a thin layer of the freshly mixed seal or. The specimens were left overnight at room temperature. After their initial set, they were transferred to an incubator at $37$^{\circ}C$ for 72 h. After 72 hours, resin blocks were made. The resin block was serially sectioned vertically into stick of $1{\cdot}1mm$. Twenty sticks were prepared from each group. After that, tensile bond strength f3r each stick was measured with Microtensile Tester Failure patterns of the specimens at the interface between gutta-percha and dentin were observed under the SEM(x1000) and Stereomicroscope (LEICA M42O, Meyer Inst., TX U.S.A) at 1.25 x25 magnification. The results were statistically analysed by using a One-way ANOVA and Tukey's test. The results were as follows; 1. Tensile bond strengths($mean{\pm}SD$) were expressed with ascending order as follows: Group 1, $3.09{\pm}$ 1.05Mpa : Group 2, $6.23{\pm}1.16MPa$ : Group 3, $7.12{\pm}1.07MPa$ : Group 4, $10.32{\pm}2.06MPa$. 2. Tensile bond strengths of the group 2 and 4 used disks of gutta-percha for conventional obturation were significantly higher than that of the group 1 and 3 used fir thermoplastic obturation. (p < 0.05). 3. Tensile bond strengths of the group 3 and 4 treated with 2% NaOC1+17% EDTA were significantly higher than that of the group 1 and 2 treated with 2% NaOCl. (p < 0.05). 4. In analysis of failure patterns at the interface between sealer and gutta-percha, there were observed 49 (61%)cases of adhesive failure patterns and 31 (39%) cases of mixed failures patterns.

• Restorative Dentistry and Endodontics
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• v.13 no.1
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• pp.103-111
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• 1988

The purpose of this study was to, examine the sealing ability of the denting bonding agent, when used with gutta percha cone, as a root canal sealer. Seventy two upper and lower extracted human teeth with single root were randomly selected and instrumented in a conventional method with K-file. After instrumentation and dry the canal with paper point, there were divided into three groups and twenty four teeth in each group were filled with the following material; In group I: Scotchbond in combination with gutta percha cone. In group II: AH 26 in combination with gutta percha cone. In group III: Tubli-Seal in combination with gutta percha cone. All specimens were immersed in Indian Ink, decalcified, and cleared. The depth of dye penetration into the canals were evaluated by caliper at the intervals of 1 day, 1 week, 2 weeks. The results were as follows; 1. Depth of dye penetration for all groups increased with time. 2. As to difference in mean dye penetration at time interval of 1 day and 14 days, Scotchbond group exhibited the smallest value as 0.53mm and Tubli-Seal group exhibited the largest value as 0.70mm. 3. There was the difference of dye penetration between each group, but its difference was not significant, statistically.