• Proceedings of the Korean Society of Propulsion Engineers Conference
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• 2011.04a
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• pp.465-465
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• 2011

Rolls-Royce is a global company producing advanced power systems for use on land, at sea and in the air. In order to develop competitive products and services, Rolls-Royce invests in technology, infrastructure and capability with much of the research carried out in a global network of University Technology Centres, such as the UTC in Thermal management at Pusan National University. Heat exchangers and thermal management play a critical role in today's gas turbine engines, maintaining the fuel and oil temperatures within the correct operational range. Future products are likely to place an increased duty on the thermal management system and thus require advances in heat exchanger design, installation and manufacturing. Heat exchangers further have the potential to play a vital role in Advanced Cycle Gas Turbine products. The Intercooled and recuperated WR21 marine gas turbine engine recently entered service with the Royal Navy and is delivering very attractive fuel burn in service. The development of an advanced cycle aero-engine is a significantly greater challenge, requiring better understanding of compact and light weight heat exchanger surfaces, novel installations and ducting systems and may required novel manufacturing techniques to achieve the volume, weight and cost necessary to realise a viable advanced cycle gas turbine aero-engine.

• Journal of Dairy Science and Biotechnology
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• v.37 no.2
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• pp.83-93
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• 2019

Food spoilage by fungi is responsible for considerable food waste and economical losses. Among the food products, fermented dairy products are susceptible to deterioration due to the growth of fungi, which are resistant to low pH and can proliferate at low storage temperatures. For controlling fungal growth in dairy products, potassium sorbate and natamycin are the main preservatives used, and natamycin is approved by most countries for use in cheese surface treatment. However, a strong societal demand for less processed and preservative-free food has emerged. In the dairy products, lactic acid bacteria (LAB) are naturally present or used as cultures and play a key role in the fermentation process. Fermentation is a natural preservation technique that improves food safety, nutritional value, and specific organoleptic features. Production of organic acids is one of the main features of the LAB used for outcompeting organisms that cause spoilage, although other mechanisms such as antifungal peptides obtained from the cleavage of food proteins and competition for nutrients also play a role. More studies for better understanding these mechanisms are required to increase antifungal LAB available in the market.

• Korean Circulation Journal
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• v.48 no.12
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• pp.1135-1144
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• 2018

Background and Objectives: Mitochondria play a key role in the pathophysiology of heart failure and mitochondrial permeability transition pore (MPTP) play a critical role in cell death and a critical target for cardioprotection. The aim of this study was to evaluate the protective effects of cyclosporine A (CsA), one of MPTP blockers, and morphological changes of mitochondria and MPTP related proteins in monocrotaline (MCT) induced pulmonary arterial hypertension (PAH). Methods: Eight weeks old Sprague-Dawley rats were randomized to control, MCT (60 mg/kg) and MCT plus CsA (10 mg/kg/day) treatment groups. Four weeks later, right ventricular hypertrophy (RVH) and morphological changes of right ventricle (RV) were done. Western blot and reverse transcription polymerase chain reaction (RT-PCR) for MPTP related protein were performed. Results: In electron microscopy, CsA treatment prevented MCT-induced mitochondrial disruption of RV. RVH was significantly increased in MCT group compared to that of the controls but RVH was more increased with CsA treatment. Thickened medial wall thickness of pulmonary arteriole in PAH was not changed after CsA treatment. In western blot, caspase-3 was significantly increased in MCT group, and was attenuated in CsA treatment. There were no significant differences in voltage-dependent anion channel, adenine nucleotide translocator 1 and cyclophilin D expression in western blot and RT-PCR between the 3 groups. Conclusions: CsA reduces MCT induced RV mitochondrial damage. Although, MPTP blocking does not reverse pulmonary pathology, it may reduce RV dysfunction in PAH. The results suggest that it could serve as an adjunctive therapy to PAH treatment.

• Journal of Korean Neurosurgical Society
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• v.62 no.1
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• pp.123-129
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• 2019

Objective : Ventriculoperitoneal (VP) shunt surgery is a common and effective treatment for hydrocephalus and cerebrospinal fluid disorders. Infection remains a major cause of morbidity and mortality after a VP shunt. There is evidence that a deep skin flora microbiome may have a role to play in post-operative infections. In this technical note, we present a skin preparation technique that addresses the issue of the skin flora beyond the initial incision. Methods : The patient is initially prepped, as standard, with. a single layer of 2% CHG+70% isopropyl alcohol. The novel stage is the 'double incision' whereby an initial superficial incision receives a further application of povidone-iodine prior to completing the full depth incision. Results : Of the 84 shunts inserted using the double-incision method (September 2015 to September 2016), only one developed a shunt infection. Conclusion : The double incision approach to skin preparation is a unique operative stage in VP shunt surgery that may have a role to play in reducing acute shunt infection.

• Safety and Health at Work
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• v.9 no.4
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• pp.447-453
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• 2018

Background: Patient safety and accurate implementation of medication orders are among the essential requirements of par nursing profession. In this regard, it is necessary to determine and prevent factors influencing medications errors. Although many studies have investigated this issue, the effects of psychosocial factors have not been examined thoroughly. Methods: The present study aimed at investigating the impact of psychosocial factors on nurses' medication errors by evaluating the balance between effort and reward. This cross-sectional descriptive study was conducted in public hospitals of Tehran in 2015. The population of this work consisted of 379 nurses. A multisection questionnaire was used for data collection. Results: In this research, 29% of participating nurses reported medication errors in 2015. Most frequent errors were related to wrong dosage, drug, and patient. There were significant relationships between medications errors and the stress of imbalance between effort and reward (p < 0.02) and job commitment and stress (p < 0.027). Conclusion: It seems that several factors play a role in the occurrence of medication errors, and psychosocial factors play a crucial and major role in this regard. Therefore, it is necessary to investigate these factors in more detail and take them into account in the hospital management.

• Journal of Korean Biological Nursing Science
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• v.21 no.2
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• pp.152-159
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• 2019

Purpose: To understand awareness, attitude and knowledge levels of muscle health of adults over 18 years old. Methods: This study was a cross-sectional study using questionnaires. A total of 401 questionnaires were included for final analysis. Mean and standard deviation of the continuous variables were analyzed and frequency analysis of categorical variables was performed. To identify differences according to general characteristics, t-test was used. Results: Awareness scores about the importance of muscle health and exercises were 8.3 and 13.0, respectively. Attitude score and knowledge score were 12.4 and 15.0, respectively. There were differences in attitude toward muscle health according to gender, age, physical activity, and diet habits. However, there was no difference in attitude toward muscle health according to educational level, smoking, drinking, or sleeping. Conclusion: It is necessary to seek a strategy to improve awareness and attitude toward muscle health based on knowledge, not merely to raise knowledge level about muscle health. Since nurses play a central role in health promotion and disease prevention, they should also play an important role in strategic development and application of intervention.

• East Asian Journal of Business Economics (EAJBE)
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• v.10 no.4
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• pp.65-74
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• 2022

Purpose - With the increasing medical demands of the public, the development of future Internet medical care has come to represent a major problem. Therefore, the purpose of this study is to discuss future development strategies for Interne medical care while taking China's Internet hospitals as an example case. Research design, data, and methodology - This study conducted a case study of China's Internet hospitals to summarize the fundamental problems faced by Internet hospitals and propose future development strategies to overcome these problems for Internet medical care. Result - Although Internet hospitals have been regarded as the ultimate product of Internet medical care, from the perspective of the government, medical institutions, platforms builders and maintainers, and patients, they still face some basic issues. Conclusion - This study concludes that the government and medical institutions play an important role in the future development of Internet medical care and suggests that the government should make overall plans for the policies and standards and should play the main role in enhancing the public trust in Internet medical care, while medical institutions should take steps such as seizing policy opportunities, driving online and offline collaborations, and constructing suitable evaluation systems to promote the development of Internet medical care.

• Korea Trade Review
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• v.44 no.5
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• pp.65-92
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• 2019

The purposes of this study are to examine the impact of LMX on psychological empowerment, job engagement, and customer orientation, and to analyze the dual mediation effect of psychological empowerment and job engagement. To conduct this study, we used 333 questionnaires collected by members of domestic companies and organizations. Analyses results are as follows: First, LMX has no positive effect on customer orientation. Second, in the relationship between LMX and customer orientation, psychological empowerment and job engagement play a mediating role. Third, in the relationship between LMX and customer orientation, psychological empowerment and Job Engagement play a dual mediating role. The results of this study suggest the following implications. The theoretical implication is that this study once again confirmed behavior patterns such as cognition, emotion, attitude, and behavior of members in the organization. In addition, this study contributes to the literature by explaining that these behavior patterns by way of social exchange theory. The practical implication is that this study confirmed that members in the management field need to utilize a customer orientation in order to achieve the organization's goal efficiently and effectively.

• Proceedings of the PSK Conference
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• 2002.10a
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• pp.330.2-330.2
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• 2002

The conformational study on cyclic Ac-Cys-Pro-Xaa-Cys-NHMe (Ac-CPXC-NHMe: X = Ala, Val. Leu. Aib. Gly. His. Phe, Tyr. Asn. and Ser) peptides has been carried out using the ECEPP/3 force field and the hydration shell model in the unhydrated and hydrated states. This work has been undertaken to investigate structural implications of the CPXC sequence as the chain reversal for the initiation of protein folding and as the motif for active site of disulfide oxidoreductases. The backbone conformation DAAA is in common the most feasible for cyclic CPXC peptides in the hydrated state. which has a type 1${\beta}$-turn at the Pro-Xaa sequence. The proline residue and the hydrogen bond between backbones of two cystines appear to play a role in stabilizing this preferred conformation of cycilc CPXC peptides. However. the distributions of backbone conformations and ${\beta}$-turns may indicate that the cyclic CPXC peptide seems to exist as an ensemble of ${\beta}$-turns and coiled conformations. The intirnsic stability of the cyclic CPXC motif itself the active conformation appears to play a role in determining electrochemical properties of disulfide oxidoreductases.

• The Journal of Asian Finance, Economics and Business
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• v.9 no.6
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• pp.325-329
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• 2022

Enterprises play an increasingly important role in economic development in each country. Effective businesses will make the economies of countries also become efficient and develop. Enterprises play a role in creating jobs, improving labor productivity, and connecting foreign trade and import-export activities. The study aims to evaluate the factors affecting the profitability of small and medium enterprises in Hanoi by using a study of 210 enterprises in the area as well as advanced econometric regression analysis. The research results show that firm size and human capital have no impact on business performance. However, older firms are likely to have higher firm performance, and conversely, younger firms have lower firm performance. The research also confirms that the growth of businesses often has higher firm performance than low-growth ones. Furthermore, a firm with greater value is also more likely to stimulate business performance than lower its value, and this effect is the largest among the analyzed factors. Finally, the study also has some recommendations for the Vietnamese government to develop small and medium enterprises. Specifically, the government needs to create an open mechanism for the start-up movement and create a favorable financial mechanism for small and medium-sized enterprises to be able to access.